{"title":"[氨基酸在创伤后急性代偿性肾功能衰竭中的应用]。","authors":"E Bock","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Three patient groups compensated acute renal failure and previous surgery were evaluated, who had been nourished isocaloric (1700 kcal) and practically isonitrogen (33-35 g amino acid), but of various mixtures of amino acids. Besides the uniform daily energy intake of 750 ml of 40% invert sugar and 250 ml of 20% Lipofundin, the daily amino acid infusion of group I (n = 13) was only 500 ml EAS pfrimmer (34.5 g), of group II (n = 10) 250 ml EAS pfrimmer and 250 ml of 7.5% Intrafusin, and of group III (n = 16) 250 ml EAS pfrimmer and 350 ml Aminofusin Hepar (33.1 g). During evaluation of the aminograms, low initial values under the bottom reference region of glycine, serine, arginine and histidine in serum were recorded at the start of the trial in all 3 patient groups. During the course of the 4-day infusion therapy, the serum values of patients in groups II and III appeared to improve more than those in group I. Contrarily, the serum levels of phenylalanine, methionine and 3-methyl histidine were 2-3 times higher than the reference region at the start of the trial. With regard to a decrease in the high serum levels, patient group II appeared to be superior to groups I and III. No significant differences were observed during the clinical course.</p>","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"13 6","pages":"254-60"},"PeriodicalIF":0.0000,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Amino acid administration in acute, compensated renal failure in the post-traumatic phase].\",\"authors\":\"E Bock\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Three patient groups compensated acute renal failure and previous surgery were evaluated, who had been nourished isocaloric (1700 kcal) and practically isonitrogen (33-35 g amino acid), but of various mixtures of amino acids. Besides the uniform daily energy intake of 750 ml of 40% invert sugar and 250 ml of 20% Lipofundin, the daily amino acid infusion of group I (n = 13) was only 500 ml EAS pfrimmer (34.5 g), of group II (n = 10) 250 ml EAS pfrimmer and 250 ml of 7.5% Intrafusin, and of group III (n = 16) 250 ml EAS pfrimmer and 350 ml Aminofusin Hepar (33.1 g). During evaluation of the aminograms, low initial values under the bottom reference region of glycine, serine, arginine and histidine in serum were recorded at the start of the trial in all 3 patient groups. During the course of the 4-day infusion therapy, the serum values of patients in groups II and III appeared to improve more than those in group I. Contrarily, the serum levels of phenylalanine, methionine and 3-methyl histidine were 2-3 times higher than the reference region at the start of the trial. With regard to a decrease in the high serum levels, patient group II appeared to be superior to groups I and III. No significant differences were observed during the clinical course.</p>\",\"PeriodicalId\":75931,\"journal\":{\"name\":\"Infusionstherapie und klinische Ernahrung\",\"volume\":\"13 6\",\"pages\":\"254-60\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1986-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infusionstherapie und klinische Ernahrung\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infusionstherapie und klinische Ernahrung","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
三组患者补偿急性肾功能衰竭和既往手术进行评估,谁曾被滋养等热量(1700千卡)和实际等氮(33-35克氨基酸),但不同的氨基酸混合物。除了统一的每日能量摄入750毫升的40%转化糖和250毫升的20% Lipofundin,每日氨基酸输液组(n = 13)只有500毫升EAS pfrimmer (34.5 g),第二组(n = 10) Intrafusin EAS pfrimmer 250毫升和250毫升的7.5%,和第三组(n = 16) EAS pfrimmer 250毫升和350毫升Aminofusin肝(33.1 g)。在氨基酸谱的评价,较低的初始值在底部参考地区的甘氨酸,丝氨酸,在试验开始时记录3组患者血清精氨酸和组氨酸水平。在4天的输注治疗过程中,II组和III组患者的血清值比i组改善更多,相反,苯丙氨酸、蛋氨酸和3-甲基组氨酸的血清水平在试验开始时比参考区域高2-3倍。关于高血清水平的降低,患者II组似乎优于I组和III组。在临床过程中未观察到显著差异。
[Amino acid administration in acute, compensated renal failure in the post-traumatic phase].
Three patient groups compensated acute renal failure and previous surgery were evaluated, who had been nourished isocaloric (1700 kcal) and practically isonitrogen (33-35 g amino acid), but of various mixtures of amino acids. Besides the uniform daily energy intake of 750 ml of 40% invert sugar and 250 ml of 20% Lipofundin, the daily amino acid infusion of group I (n = 13) was only 500 ml EAS pfrimmer (34.5 g), of group II (n = 10) 250 ml EAS pfrimmer and 250 ml of 7.5% Intrafusin, and of group III (n = 16) 250 ml EAS pfrimmer and 350 ml Aminofusin Hepar (33.1 g). During evaluation of the aminograms, low initial values under the bottom reference region of glycine, serine, arginine and histidine in serum were recorded at the start of the trial in all 3 patient groups. During the course of the 4-day infusion therapy, the serum values of patients in groups II and III appeared to improve more than those in group I. Contrarily, the serum levels of phenylalanine, methionine and 3-methyl histidine were 2-3 times higher than the reference region at the start of the trial. With regard to a decrease in the high serum levels, patient group II appeared to be superior to groups I and III. No significant differences were observed during the clinical course.