[Amino acid administration in acute, compensated renal failure in the post-traumatic phase].

Abstract

Three patient groups compensated acute renal failure and previous surgery were evaluated, who had been nourished isocaloric (1700 kcal) and practically isonitrogen (33-35 g amino acid), but of various mixtures of amino acids. Besides the uniform daily energy intake of 750 ml of 40% invert sugar and 250 ml of 20% Lipofundin, the daily amino acid infusion of group I (n = 13) was only 500 ml EAS pfrimmer (34.5 g), of group II (n = 10) 250 ml EAS pfrimmer and 250 ml of 7.5% Intrafusin, and of group III (n = 16) 250 ml EAS pfrimmer and 350 ml Aminofusin Hepar (33.1 g). During evaluation of the aminograms, low initial values under the bottom reference region of glycine, serine, arginine and histidine in serum were recorded at the start of the trial in all 3 patient groups. During the course of the 4-day infusion therapy, the serum values of patients in groups II and III appeared to improve more than those in group I. Contrarily, the serum levels of phenylalanine, methionine and 3-methyl histidine were 2-3 times higher than the reference region at the start of the trial. With regard to a decrease in the high serum levels, patient group II appeared to be superior to groups I and III. No significant differences were observed during the clinical course.