Infusionstherapie und klinische Ernahrung最新文献_第5页

The safety of and the strain on the donor during thrombocytapheresis on the cell separator. A psychological study. 细胞分离器上采血小板过程中供体的安全性和毒株。一项心理学研究。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-09-01 DOI: 10.1159/000226203

H D Basler, C Steinfelder, U Hartnack, V Kretschmer

{"title":"The safety of and the strain on the donor during thrombocytapheresis on the cell separator. A psychological study.","authors":"H D Basler, C Steinfelder, U Hartnack, V Kretschmer","doi":"10.1159/000226203","DOIUrl":"https://doi.org/10.1159/000226203","url":null,"abstract":"The study deals with the question as to what extent and under which existing personal characteristics does thrombocytapheresis on the cell separator (Fenwal CS-3000) lead to psychological stress for the blood donor? A comparison is made with the stress experienced during the established 450 ml full-blood donation. Because of the different procedural conditions, it was postulated that the donation on the cell separator creates greater psychological stress than the established type of donation. To examine this hypothesis, a sample group of 76 cell-separator and full-blood donors were asked to complete a questionnaire concerning the stress they experienced and their attitude before, during, and after the donation. Their personalities were also examined. A control group of 45 full-blood donors was examined in the same way. No significant statistical difference was found regarding the extent of stress under both conditions of donation. These findings are verified by the general satisfaction expressed by the cell-separator donors. Although it is confirmed that the personal cost to the donor is greater, it involves, on the other hand, a greater commitment, a positive evaluation of the more intimate involvement of the donor, and an increase in self-esteem. Since it could not be proven that there is an increase in the amount of stress during cell-separator donation, it also seems plausible that no clear decrease in stress would be observed after repeated donations. On the whole, it seems that the cell separator is well accepted by the donors. The extent of experienced stress is related to the donor's habitual anxiety and negative expectations. Since negative expectations can be influenced, it is to be expected that an informative conversation in a quiet atmosphere would further decrease the stress experienced.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"14 Suppl 4 ","pages":"36-42"},"PeriodicalIF":0.0,"publicationDate":"1987-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000226203","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14799033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

[Implementation of apparative hemapheresis for collecting blood component stores. Recommendations of the Hemapheresis Commission of the German Society of Transfusion Medicine and Immunohematology]. 实施幻影采血法采集血液成分库。德国输血医学和免疫血液学学会的采血委员会的建议]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-09-01

V Kretschmer, H Borberg, D Giannitsis, D Kamanabroo, W Mempel, V Müller, N Müller, H Neumeyer

引用次数: 0

Side-effects and technical problems in cytapheresis with cell separators. Results of a retrospective multicenter study. 用细胞分离器进行细胞分离的副作用和技术问题。一项回顾性多中心研究结果。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-09-01 DOI: 10.1159/000226199

V Kretschmer

{"title":"Side-effects and technical problems in cytapheresis with cell separators. Results of a retrospective multicenter study.","authors":"V Kretschmer","doi":"10.1159/000226199","DOIUrl":"https://doi.org/10.1159/000226199","url":null,"abstract":"On the basis of a survey, the acute side-effects and technical problems in a total of 77,525 cytaphereses (IFC 36,530, CFC 40,995) in donors at 39 hemapheresis centers were retrospectively analysed statistically. In general, relevant donor side-effects (0.78%-1.05%) were more rare than the primary donor-independent disturbances (1.65%-2.63%). The donor side-effects predominated merely with the use of the cell separators Haemonetics M30/Belco (1.06% vs. 0.57%). These were mainly circulatory reactions (0.83%), which were generally much more frequent with IFC (0.54%) than with CFC (IBM/Cobe 0.11%, CS-3000 0.19%). Potentially fatal complications were not reported. The frequency of side-effects, disturbances and discontinuations correlated inversely with the separation rate of the individual centers per method. Centers in which two or three methods were applied simultaneously reported a higher frequency of side-effects and disturbances. Hemolysis was only observed with IFC (0.09%), but not with the use of the Haemonetics V50. The greater susceptibility to disturbances of technical/methodological/operational origin essentially results from the more elaborate, but not yet perfected technology, including computer control and monitoring, as well as defects in the production of the much more complicated disposable sets. Thus the highest rate of discontinuations was calculated for the system which is so far the most sophisticated technically (CS-3000, 1.85%). Although the primary donor-independent problems sometimes correlate directly with the manifestation of donor side-effects, the greater technological sophistication of automatically controlled and monitored systems cannot be dispensed with, since only in this way can potentially fatal risks for the donors be largely ruled out.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"14 Suppl 4 ","pages":"7-16"},"PeriodicalIF":0.0,"publicationDate":"1987-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000226199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14443633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

[The safety of apparative cytapheresis]. 【幻影取卵术的安全性】。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-09-01

R Böhm, H Borberg

{"title":"[The safety of apparative cytapheresis].","authors":"R Böhm, H Borberg","doi":"","DOIUrl":"","url":null,"abstract":"In a retrospective analysis 1568 platelet apheresis procedures and 652 leukocytophereses performed from April 1976 to June 1986 were examined. 886 procedures were performed using the Fenwal CS 3000, 777 with the IBM 2997, and 293 with the Haemonetics V50, whereas in 264 procedures the Model 30 was used. The study aims to answer 3 donor-related questions: To what extent are the blood cells changed by the donation? How does the donor respond to the technical requirements of the donation, such as length of the procedure, blood volume processed, amount of concentrate removed during the donation? How often did side-effects or undesired reactions occur? We found that thrombocytapheresis led to a decrease in platelets in the peripheral blood of between 20% (CS3000) and 33.7% (IBM), and an increase in leukocytes of between 4.24% (IBM) and 17.8% (Model 30), whereas erythrocytes, hemoglobin and hematocrit showed a similar decrease within a range of between 1.1% and 2.67% in all systems. Following leukocytapheresis the leukocyte counts of the peripheral blood were decreased by up to 12%, erythrocyte counts by up to 5% and platelets between 15% (IBM) and 29% (Model 30). The list of irregularities included technical problems and donor reactions (e.g., citrate reactions, reactions of blood circulation, and blood flow in the donor). There were no serious side-effects. Early terminations of 42 (= 1.9%) donations were for prophylactic reasons exclusively. Few moderate undesired reactions occurred (4 = 0.2%), but none of the donors contributing to the more than 2,000 donations were ever hospitalized, demonstrating the safety of cytapheresis with all separators.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"14 Suppl 4 ","pages":"18-27"},"PeriodicalIF":0.0,"publicationDate":"1987-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14799031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Intracellular amino acid concentrations in various disease states]. [不同疾病状态下的细胞内氨基酸浓度]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-08-01

E Roth, J Karner

引用次数: 0

Isolated perfused rat liver: an experimental model for studies on ammonium and amino acid metabolism. 离体灌注大鼠肝脏:氨和氨基酸代谢研究的实验模型。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-08-01 DOI: 10.1159/000222210

D Häussinger

{"title":"Isolated perfused rat liver: an experimental model for studies on ammonium and amino acid metabolism.","authors":"D Häussinger","doi":"10.1159/000222210","DOIUrl":"https://doi.org/10.1159/000222210","url":null,"abstract":"Isolated perfused rat liver is a well-established experimental model for studies on hepatic amino acid and ammonia metabolism. Some aspects and modifications of the liver-perfusion technique are discussed. Perfusion studies with the intact liver have the fundamental advantage that the structural and functional organization of the liver is preserved; however, the experimental system is more complex in view of subcellular and intercellular compartmentation and the recently demonstrated metabolic interactions of different cell populations at the acinar level. These problems of complexity by compartmentation can be largely solved by introducing further techniques such as organ spectrophotometry, the retrograde/antegrade perfusion technique, use of micro-oxygen-electrodes, use of selective inhibitors, radiolabeled compounds, different fractionation techniques of the liver tissue. By means of these approaches, intracellular events can be followed up not only indirectly by analyzing the composition of the perfusate before and after a liver passage, but also directly in the different subcellular and subacinar compartments of a structurally and metabolically intact liver.","PeriodicalId":75931,"journal":{"name":"Infusionstherapie und klinische Ernahrung","volume":"14 4","pages":"174-8"},"PeriodicalIF":0.0,"publicationDate":"1987-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000222210","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14799904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Intrazelluläre Aminosäurenkonzentrationen bei verschiedenen Krankheitszuständen 不同状态下的细胞内氨基酸浓度

Infusionstherapie und klinische Ernahrung Pub Date : 1987-08-01 DOI: 10.1159/000222204

E. Roth, J. Karner

引用次数: 0

[Hepatic vein catheter technic: method for the detection of metabolic and hormonal variables in the splanchnic area]. [肝静脉导管技术:内脏区代谢和激素变量的检测方法]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-08-01

P R Bratusch-Marrain, S Gasic

引用次数: 0

[The isolated perfused hindlimb of the rat. Method and use]. [离体灌注的大鼠后肢。方法和用途]。

Infusionstherapie und klinische Ernahrung Pub Date : 1987-08-01

P Schadewaldt