AIDS and Behavior最新文献_第7页

Test-to-PrEP: An Egocentric Approach to Promoting HIV Discussions and Resource Sharing in PrEP Clients’ Social Networks 测试到PrEP：在PrEP客户的社会网络中促进HIV讨论和资源共享的自我中心方法。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04635-9

E. Rodriguez, A. L. Johnson, L. Craker, S. Butts, M. Kanamori, Susanne Doblecki-Lewis

{"title":"Test-to-PrEP: An Egocentric Approach to Promoting HIV Discussions and Resource Sharing in PrEP Clients’ Social Networks","authors":"E. Rodriguez, A. L. Johnson, L. Craker, S. Butts, M. Kanamori, Susanne Doblecki-Lewis","doi":"10.1007/s10461-025-04635-9","DOIUrl":"10.1007/s10461-025-04635-9","url":null,"abstract":"<div><p>Test-to-PrEP, a bundled HIV self-test (HIVST) and PrEP educational kit was distributed to the social networks (SN) of PrEP clients using social network strategies (SNS). PrEP clients (<i>n</i> = 100) distributed kits to their SN members (<i>n</i> = 415). Multilevel analysis assessed the relationship between demographic/network characteristics and likelihood of PrEP discussions. Higher network density (e.g., the level of linkage among network members) and daily contact were associated with having previously talked about PrEP. Networks that were denser (more ties/connections), more frequently in contact, and had a relationship type that assumes greater closeness (proximal relations) resulted in greater likelihood of having had PrEP conversations. This work demonstrates the feasibility of using SNS to increase routine HIV testing and PrEP knowledge. The Test-To-PrEP SNS strategy is a promising tool to increase HIV prevention and care access to all who may benefit.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1663 - 1668"},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-025-04635-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Individual and Contextual Determinants of ART Adherence Among a Sample of Young Black Gay, Bisexual, and Other Men Who Have Sex with Men Living with HIV in the United States. 美国年轻黑人同性恋、双性恋和其他与艾滋病毒感染者发生性行为的男性样本中抗逆转录病毒治疗依从性的个体和环境决定因素

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04650-w

Casey Morgan Luc, Kara Herrera, Sierra Upton, Jeb Jones, Meaghan Woody, Paul Burns, Li Liu, Antonio Jimenez, Mark S Dworkin

{"title":"Individual and Contextual Determinants of ART Adherence Among a Sample of Young Black Gay, Bisexual, and Other Men Who Have Sex with Men Living with HIV in the United States.","authors":"Casey Morgan Luc, Kara Herrera, Sierra Upton, Jeb Jones, Meaghan Woody, Paul Burns, Li Liu, Antonio Jimenez, Mark S Dworkin","doi":"10.1007/s10461-025-04650-w","DOIUrl":"https://doi.org/10.1007/s10461-025-04650-w","url":null,"abstract":"<p><p>The Information-Motivation-Behavioral Skills (IMB) model of antiretroviral therapy (ART) adherence describes self-reported ART adherence determinants among people living with HIV (PLWH) who struggle to achieve optimal adherence, but less is known about young Black gay, bisexual, and other men who have sex with men (MSM), a group reported to have less than optimal ART adherence levels, partially affected by depression. Using the IMB model, we analyzed baseline data from 315 Black MSM living with HIV aged 18-34 years struggling with ART adherence enrolled in a multi-state mobile health (mHealth) randomized controlled trial. Generalized structural equation modeling was used to estimate the direct and indirect effects of (1) ART-related information, (2) motivation and (3) behavioral skills, or treatment self-efficacy, on non-optimal self-reported ART adherence (< 80%, Wilson's adherence measure). Prevalence of non-optimal ART adherence was 28.3%. Low behavioral skills were directly associated with non-optimal ART adherence (β = 0.69, SE = 0.10, p <.001). Low behavioral skills significantly mediated the relationship between low motivation and non-optimal ART adherence (Sobel z = 4.12, p <.001). Low information was not associated with treatment self-efficacy. Low motivation had a greater overall effect on non-optimal ART adherence among those with none/mild depressive symptomatology (β = 0.30, SE = 0.13, p <.001), and the direct effect of low motivation on non-optimal adherence was null among those with moderate/severe depressive symptomatology. Development of combination HIV prevention interventions designed to improve ART adherence should combine culturally appropriate mental health care into HIV treatment that go beyond social support among those who may be experiencing depressive symptomatology.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pain Severity and Experiences with Pain Management Predict Alcohol Use Among Men Who Have Sex with Men Living with HIV. 与艾滋病毒感染者发生性行为的男性中，疼痛严重程度和疼痛管理经历可预测其酒精使用情况。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04652-8

Erin Ferguson, David W Pantalone, Peter M Monti, Kenneth H Mayer, Christopher W Kahler

{"title":"Pain Severity and Experiences with Pain Management Predict Alcohol Use Among Men Who Have Sex with Men Living with HIV.","authors":"Erin Ferguson, David W Pantalone, Peter M Monti, Kenneth H Mayer, Christopher W Kahler","doi":"10.1007/s10461-025-04652-8","DOIUrl":"10.1007/s10461-025-04652-8","url":null,"abstract":"<p><p>Unhealthy alcohol use is prevalent among people with HIV, particularly among men who have sex with men (MSM). Pain frequently co-occurs with unhealthy alcohol use and is associated with suboptimal HIV care outcomes. The present study examined the effects of pain severity and experiences with pain management care (i.e., satisfied, dissatisfied, managing pain on own) on alcohol use. Participants were MSM with HIV reporting heavy alcohol use and pain in the past 30 days who were enrolled in a clinical trial targeting alcohol use (N = 125, 78.4% White, M<sub>age</sub>=41.2). Participants completed measures of unhealthy alcohol use [alcohol-related problems, heavy drinking days, drinks per week, drinking to manage pain (yes/no)], pain severity, and pain management care experiences. An analysis of variance examined differences in pain severity by pain management experience. Regression analyses examined the associations of pain severity and pain management experience with unhealthy alcohol use. Pain severity was significantly associated with drinking to manage pain and heavy drinking days, but not drinks per week or alcohol-related problems. MSM with HIV who were dissatisfied with pain care reported significantly greater pain severity compared to those who were satisfied or managing pain on their own. Compared to satisfaction, dissatisfaction with pain care was also associated with significantly higher odds of drinking to manage pain, although the inclusion of pain severity attenuated this association. Results highlight pain severity as a key factor related to pain management experience and unhealthy alcohol use among MSM with HIV. Future studies should prioritize pain-alcohol integrated intervention development.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting Trajectories of Everyday Functioning in Adults Aging with HIV Using Latent Growth Mixture Modeling 使用潜伏生长混合物模型预测成年HIV感染者的日常功能轨迹。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04623-z

Lillian Ham, Scott Roesch, Donald R. Franklin, Ronald J. Ellis, Igor Grant, David J. Moore

{"title":"Predicting Trajectories of Everyday Functioning in Adults Aging with HIV Using Latent Growth Mixture Modeling","authors":"Lillian Ham, Scott Roesch, Donald R. Franklin, Ronald J. Ellis, Igor Grant, David J. Moore","doi":"10.1007/s10461-025-04623-z","DOIUrl":"10.1007/s10461-025-04623-z","url":null,"abstract":"<div><p>As the U.S. population of people with HIV (PWH) ages, PWH exhibit high rates of adverse health outcomes including everyday functioning decline. We aimed to (1) identify trajectories of self-reported everyday functioning and (2) examine baseline predictors (demographics, cognitive domains, psychiatric and medical comorbidities, HIV-disease characteristics) of trajectories among PWH. 742 PWH completed up to five semi-annual visits over two years. Latent growth mixture modeling identified a linear 3-class solution with good statistical fit and interpretability. Most PWH (88%) had good baseline functioning with stability. Two classes had elevated baseline functional declines with worsening (7%) or improvement (5%). Greater depressive symptoms and motor skills impairment predicted higher odds of impaired functioning. Having chronic pulmonary disease increased odds of improvement, which may reflect connection to care, while older age increased odds of worsening. Most aging PWH demonstrate stable everyday functioning; however, interventions for depression and motor skills may improve functioning.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1525 - 1539"},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-025-04623-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Peer Referral on Pre-Exposure Prophylaxis Adherence and Persistence Among Men Who Have Sex with Men: A Cohort Study in China. 同伴转诊对中国男男性行为者暴露前预防依从性和持久性的影响：一项队列研究

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04651-9

Chengxin Fan, Zhuoheng Yin, Chunyan Li, Yifan Dai, Heping Zhao, Gifty Marley, Quanmin Li, Songjie Wu, Haojie Huang, Aniruddha Hazra, Jonathan Lio, Ke Liang, Linghua Li, Renslow Sherer, Joseph D Tucker, Weiming Tang

{"title":"Impact of Peer Referral on Pre-Exposure Prophylaxis Adherence and Persistence Among Men Who Have Sex with Men: A Cohort Study in China.","authors":"Chengxin Fan, Zhuoheng Yin, Chunyan Li, Yifan Dai, Heping Zhao, Gifty Marley, Quanmin Li, Songjie Wu, Haojie Huang, Aniruddha Hazra, Jonathan Lio, Ke Liang, Linghua Li, Renslow Sherer, Joseph D Tucker, Weiming Tang","doi":"10.1007/s10461-025-04651-9","DOIUrl":"https://doi.org/10.1007/s10461-025-04651-9","url":null,"abstract":"<p><p>Peer referral leverages social networks to connect individuals with health services, potentially enhancing pre-exposure prophylaxis (PrEP) use. This study aims to investigate the impact of peer referral on PrEP adherence and persistence among men who have sex with men (MSM) in China. This study is nested in a 12-month PrEP (FTC/TDF) demonstration trial in China from September 2021 to December 2023. Peer referral was defined as participants being referred by peers already enrolled in the trial. PrEP adherence was measured as taking four or more pills per week for daily users or following the 2 + 1 + 1 event-driven regimen at least 75% of the time. PrEP persistence was defined as the time from initiation to discontinuation. We collected data from the first 6 months of follow-up and used generalized estimating equations and Cox regression models to evaluate the association between peer referral and PrEP adherence and persistence. A total of 1,131 MSM initiated PrEP, with 121 (10.7%) referred by peers. At month 6, adherence rates were 75.0% for peer-referred MSM and 67.1% for non-peer-referred MSM. Peer-referred MSM had higher adherence than non-peer-referred MSM (aRR = 1.11, 95% CI: 1.01-1.22). Regarding persistence, 812 (71.8%) MSM continued using PrEP at 6 months of follow-up, and peer-referred MSM were more likely to persist with PrEP (aHR = 1.85, 95% CI: 1.17-2.91). These findings demonstrate the potential of peer referral in promoting PrEP use among MSM, suggesting the value of powerful peer-based interventions like peer navigation in future PrEP outreach.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19-Related Disruptions on Antiretroviral Therapy Adherence Among Young Adults Living with HIV in Southern Uganda 与covid -19相关的中断对乌干达南部感染艾滋病毒的年轻成年人坚持抗逆转录病毒治疗的影响

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04634-w

Abel Zemedkun Girma, Rachel Brathwaite, Yvonne Karamagi, Fatumah Nakabuye, Noeline Nakasujja, William Byansi, Proscovia Nabunya, Ozge Sensoy Bahar, Fred M. Ssewamala

{"title":"Impact of COVID-19-Related Disruptions on Antiretroviral Therapy Adherence Among Young Adults Living with HIV in Southern Uganda","authors":"Abel Zemedkun Girma, Rachel Brathwaite, Yvonne Karamagi, Fatumah Nakabuye, Noeline Nakasujja, William Byansi, Proscovia Nabunya, Ozge Sensoy Bahar, Fred M. Ssewamala","doi":"10.1007/s10461-025-04634-w","DOIUrl":"10.1007/s10461-025-04634-w","url":null,"abstract":"<div><p>We investigated how COVID-19-related disruptions influenced antiretroviral therapy (ART) adherence among young adults living with HIV (YALHIV) in Southern Uganda, a region with limited resources and high rates of HIV. Data were analyzed from 499 YALHIV aged 19 to 25, participating in the Suubi+Adherence-R2 COVID-19 Supplement study. The study measured COVID-19 disruptions using an 8-item Coronavirus Impact Scale and evaluated ART adherence through self-reported measures. Our analytical framework was informed by the Health Belief Model and generalized estimating equations were estimated. We find no statistically significant association between COVID-19 disruptions, as quantified by the COVID-19 Impact Score, and sub-optimal ART adherence (OR = 0.99, 95% CI [0.87–1.14]). However, findings revealed that being employed (OR = 1.99, 95% CI [1.07–3.71]) and older age (OR = 1.18, 95% CI [1.02–1.37]) was associated with higher likelihood of poor adherence highlighting the complex interplay between economic activity, working schedules, and health management. Other notable predictors included marital status, with cohabiting individuals showing decreased odds of poor adherence (OR = 0.25, 95% CI [0.08–0.74]) compared to single and separated YALHIV. These insights emphasize the need for multifaceted intervention strategies that consider both individual and systemic factors affecting ART adherence. Tailored interventions must address the socioeconomic challenges intensified by the pandemic and leverage the inherent resilience within this population to enhance ART adherence outcomes for YALHIV in challenging environments.</p><p>\u0000 <b>Trial Registration</b> ClinicalTrials.gov, ID: NCT01790373.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1640 - 1649"},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facilitators and Barriers to Hiv Pre-Exposure Prophylaxis Adherence and Retention Among Young Men Who have Sex With Men: A Meta-Ethnographic Scoping Review 年轻男男性行为者艾滋病暴露前预防依从性和保留性的促进因素和障碍：一项元人种志范围审查。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-024-04582-x

Le Anh Tuan, Loc Quang Pham, Tong Thi Khuyen, Bui Minh Hao, Nguyen Thi Phuong Hoa, Kim-Duy Vu, Tran Hoang My Lien, Pham Thi Thanh Duyen, Hai Thanh Phan, Le Minh Giang, Sophia M. Bartels, Sarah E. Rutstein

{"title":"Facilitators and Barriers to Hiv Pre-Exposure Prophylaxis Adherence and Retention Among Young Men Who have Sex With Men: A Meta-Ethnographic Scoping Review","authors":"Le Anh Tuan, Loc Quang Pham, Tong Thi Khuyen, Bui Minh Hao, Nguyen Thi Phuong Hoa, Kim-Duy Vu, Tran Hoang My Lien, Pham Thi Thanh Duyen, Hai Thanh Phan, Le Minh Giang, Sophia M. Bartels, Sarah E. Rutstein","doi":"10.1007/s10461-024-04582-x","DOIUrl":"10.1007/s10461-024-04582-x","url":null,"abstract":"<div><p>Retention and adherence to daily oral pre-exposure prophylaxis (PrEP) are critical for effective HIV prevention; however, YMSM exhibit lower rates of both compared to other populations. This is important because young men who have sex with men (YMSM) are at higher risk for HIV, and understanding their challenges can help create better support and interventions. This scoping review synthesizes evidence on the facilitators and barriers to HIV PrEP retention and adherence among YMSM, focusing on individuals aged 10 to 29 years. The review adheres to PRISMA-ScR and eMERGe guidelines, examining 14 studies involving 3,178 participants. It emphasizes the complex interactions of individual, interpersonal, community, and societal factors influencing PrEP adherence and retention. Key facilitators include psychological strategies, supportive health systems, and supportive social networks. Conversely, significant barriers encompass financial burdens, interpersonal stigma, and behavioral factors. The review highlights the critical role of tailored, multi-level interventions and the need for healthcare provider training in youth-specific approaches to care. This work contributes to a nuanced understanding of PrEP retention among YMSM, offering insights crucial for designing effective public health strategies to enhance prevention-effective PrEP utilization in this high-risk population.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 4","pages":"1075 - 1088"},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-024-04582-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying Subgroups of Intersectional Stigma, Discrimination, and the Association with Mental Health Outcomes Among HIV-Positive Men Who Have Sex with Men: A Latent Class Analysis 识别交叉污名、歧视的亚群，以及与男男性行为的hiv阳性男性心理健康结果的关联：一项潜在分类分析

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-04 DOI: 10.1007/s10461-024-04583-w

Liying Wang, Kathy Trang, Casey Xavier Hall, Lin Zhu, R. N. Eugenia Millender, Crim Sabuncu, Jack Barile, Grace Ma, Avrum Gillespie, Gina Simoncini, Frankie Wong

{"title":"Identifying Subgroups of Intersectional Stigma, Discrimination, and the Association with Mental Health Outcomes Among HIV-Positive Men Who Have Sex with Men: A Latent Class Analysis","authors":"Liying Wang, Kathy Trang, Casey Xavier Hall, Lin Zhu, R. N. Eugenia Millender, Crim Sabuncu, Jack Barile, Grace Ma, Avrum Gillespie, Gina Simoncini, Frankie Wong","doi":"10.1007/s10461-024-04583-w","DOIUrl":"10.1007/s10461-024-04583-w","url":null,"abstract":"<div><p>This study aimed to (1) identify latent classes of stigma and discrimination experiences among men who have sex with men (MSM) living with HIV; (2) examine the associations between class membership and mental health outcomes, and (3) investigate the moderating effects of social support and resilience. The study used the baseline (<i>N</i> = 224) and six-month follow-up data (<i>N</i> = 118) from a longitudinal cohort study on HIV and hypertension among African American and Asian Pacific American MSM in Hawai’i and Philadelphia from 2019 to 2023. Latent class analysis was conducted to characterize the patterns of stigma and discrimination experience. Multivariable regression was conducted to examine the association between class membership and mental health outcomes. Interaction terms were added to examine the moderation effects of social support and resilience on the association between class memberships and mental health outcomes. A five-class model was identified: Class (1) high on internalized homophobia and low on all discrimination experiences; Class (2) high on racial discrimination; Class (3) high on sexual identity discrimination; Class (4) low on internalized homophobia and all discrimination experiences; Class (5) high on physical disability discrimination and internalized homophobia. Class 5 consistently predicted worse mental health outcomes, compared to Class 4. The association between Class 2 (high racial discrimination) and depression was moderated by perceived social support. The study reveals complex experiences of intersectional stigma and discrimination among MSM living with HIV, highlighting the need for further research on the intersecting effects of multiple disadvantages among aging sexual minorities.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 3","pages":"1011 - 1027"},"PeriodicalIF":2.7,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socio-ecological Determinants of Detectable Viremia among Pregnant People Living with HIV in South Brazil: The Role of Stimulant Use Disorder and Homelessness. 在巴西南部感染HIV的孕妇中可检测到病毒血症的社会生态决定因素：兴奋剂使用障碍和无家可归的作用。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04639-5

Christopher Justin Hernandez, Fernando Echegaray, Kavya Sundar, Lanbo Z Yang, Mary Catherine Cambou, Eddy R Segura, Marineide Gonçalves de Melo, Breno Riegel Santos, Ivana Rosângela Dos Santos Varella, Karin Nielsen-Saines

{"title":"Socio-ecological Determinants of Detectable Viremia among Pregnant People Living with HIV in South Brazil: The Role of Stimulant Use Disorder and Homelessness.","authors":"Christopher Justin Hernandez, Fernando Echegaray, Kavya Sundar, Lanbo Z Yang, Mary Catherine Cambou, Eddy R Segura, Marineide Gonçalves de Melo, Breno Riegel Santos, Ivana Rosângela Dos Santos Varella, Karin Nielsen-Saines","doi":"10.1007/s10461-025-04639-5","DOIUrl":"10.1007/s10461-025-04639-5","url":null,"abstract":"<p><p>Pregnant patients living with HIV are a priority group for the recruitment into the HIV healthcare cascade to prevent adverse maternal and neonatal health outcomes. Understanding the structural, interpersonal, and individual factors that are associated with detectable HIV viremia is of importance to guide outreach and intervention priorities. This was a retrospective cohort study of pregnant patients living with HIV who delivered from January 1, 2017, to December 31, 2023, at a tertiary-level hospital and referral institution for HIV care in Porto Alegre, Brazil. The socio-ecological model was used to guide hypothesis testing regarding associations with detectable viremia. In total, 549 patients were included, of whom 110 (20%) were found to have detectable viremia. Significant differences between detectable and undetectable viremia included prenatal care, homelessness, having a sero-different partner, and stimulant use. Multivariable associations included prenatal care (adjusted Risk Ratio [aRR] = 0.20, 95% Confidence Interval [95% CI] = 0.15-0.26), homelessness (aRR = 4.02, 95% CI = 2.74-0.26), stimulant use disorder (aRR = 3.30, 95% CI = 2.23-4.87), crack use (aRR = 2.82, 95% CI = 1.85-4.29), and cocaine use (aRR = 1.89, 95% CI = 1.17-3.06). Intervention research should focus on housing and mental health services, and how to mitigate their impact on HIV healthcare. Intervention research is greatly needed as current tools may not be sufficient to tackle the issue of stimulant use disorder and its effects on ART adherence.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measuring Implementation Outcomes Change Over Time Using an Adapted Checklist for Assessing Readiness to Implement (CARI). 使用改进的实施准备评估清单（CARI）衡量实施结果随时间的变化。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04614-0

Beth Bourdeau, Mary A Guzé, Greg M Rebchook, Starley B Shade, Demetrios Psihopaidas, Nicole S Chavis, Janet J Myers

{"title":"Measuring Implementation Outcomes Change Over Time Using an Adapted Checklist for Assessing Readiness to Implement (CARI).","authors":"Beth Bourdeau, Mary A Guzé, Greg M Rebchook, Starley B Shade, Demetrios Psihopaidas, Nicole S Chavis, Janet J Myers","doi":"10.1007/s10461-025-04614-0","DOIUrl":"https://doi.org/10.1007/s10461-025-04614-0","url":null,"abstract":"<p><p>In 2017, the Health Resources and Services Administration's HIV/AIDS Bureau funded an Evaluation Center (EC) to assess the rapid implementation of 11 evidence-informed interventions at 25 HIV care and treatment providers across the U.S. The EC conducted an implementation science-based evaluation, including longitudinal assessment of implementation outcomes as defined by Implementation Outcome Framework (IOF) of the Conceptual Model for Implementation Research. The EC adapted a measure originally designed for implementation readiness to capture seven implementation outcomes and administered the measure to site leadership every six months, from intervention launch through the end of the initiative. The adapted measure demonstrated adequate internal consistency within and across time periods. Individual outcomes changed over the course of implementation, with the greatest period of growth during the first six months. Longitudinal relationships between outcomes posited to be most relevant at early, mid- or late-implementation were not evident in these analyses; rather, relationships between the outcomes were significant within time periods. Finally, there were differences in the trajectory of outcomes based on characteristics of the site's larger context. The use of this adapted measure across multiple implementation settings, assessing multiple interventions, is an important step forward in the comparability of implementation outcomes more broadly.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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