AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04701-2
Adrian Szczepański, Karolina Klesiewicz, Kamil Drożdż, Magdalena Ankiersztejn-Bartczak, Aldona Olechowska-Jarząb, Monika Brzychczy-Włoch
{"title":"Assessment of the Impact of Gender, Age, Sexual Orientation and PrEP on HIV Infection: Analysis of Anonymous HIV Tests of People in Voluntary Counselling and Testing Points (VCTs) in Poland in 2015-2023.","authors":"Adrian Szczepański, Karolina Klesiewicz, Kamil Drożdż, Magdalena Ankiersztejn-Bartczak, Aldona Olechowska-Jarząb, Monika Brzychczy-Włoch","doi":"10.1007/s10461-025-04701-2","DOIUrl":"https://doi.org/10.1007/s10461-025-04701-2","url":null,"abstract":"<p><p>Human immunodeficiency virus (HIV) is still an important global health burden and remains a common sexually transmitted infection (STI). Voluntary Counselling and Testing points (VCTs) in Poland allow free and anonymous access to HIV testing among the adult population. The aim of the study was to investigate whether there is an increased occurrence of HIV infection among individuals who identify as homosexual and to profile three distinct groups among VCTs clients: the most common patient coming for testing, the most frequent HIV-positive individual, and the most typical Pre-Exposure Prophylaxis (PrEP) user. Data obtained from 29 VCT points in Poland between 2015 and 2023 were retrospectively analyzed. The prevalence of HIV infection in this cohort was calculated and a model for HIV infection risk among various populations was built. 295,556 patient reports revealed that heterosexual men aged 25-34 years (13.43%) tested most frequently. In total, the average prevalence of HIV-positive patients amounted to 1.36%. Among the tested population, HIV infection was the most prevalent among homosexual men aged 25-34 (0.34%). Moreover, we showed that the risk of receiving a positive HIV result was almost five times higher among homosexual and bisexual patients than among heterosexual individuals. The findings highlight the urgent need for targeted HIV prevention efforts, particularly among homosexual and bisexual men. Ongoing monitoring and education are necessary even among PrEP users to prevent new infections.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04700-3
Cruz S Sebastião, Domingos Jandondo, João Vigário, Felícia António, Joana M K Sebastião, Maria L S Silva, Victor Pimentel, Ana Abecasis, Euclides Sacomboio, Jocelyne Neto Vasconcelos, Joana Morais
{"title":"Seroprevalence and Risk Factors of STIs among Rejected Blood Donors at the National Blood Transfusion Service in Angola.","authors":"Cruz S Sebastião, Domingos Jandondo, João Vigário, Felícia António, Joana M K Sebastião, Maria L S Silva, Victor Pimentel, Ana Abecasis, Euclides Sacomboio, Jocelyne Neto Vasconcelos, Joana Morais","doi":"10.1007/s10461-025-04700-3","DOIUrl":"https://doi.org/10.1007/s10461-025-04700-3","url":null,"abstract":"<p><p>Sexually transmitted infections (STIs) are a global health concern. Blood donation centres employ comprehensive screening measures to identify donors with STIs, such as HIV, HBV, HCV, and syphilis, which can also transmitted through blood transfusions. Herein, we investigated the seroprevalence of STIs and demographic determinants related to multiple infections among rejected blood donors at the National Blood Transfusion Service (NBTS) in Angola. This was a cross-sectional study conducted with 1885 rejected blood donors serologically screened for anti-HBsAg, anti-HCV, anti-HIV, and anti-TP during pre-donation screening at the NBTS, located in Luanda, the capital city of Angola, between March 2022 to July 2023. Overall, HIV (11.2%), HBsAg (71.7%), HCV (9.30%), and Syphilis (8.80%) were detected. The multiple infection rate was 2.30%. HIV and syphilis were associated with age (p < 0.05). HBV was related to age, areas of residence, and occupation (p < 0.05). HCV was related to areas of residence and educational level (p < 0.05). No relationship was observed between demographic characteristics with multiple infections (p > 0.05). Individuals aged over 40 years (OR: 2.48, p = 0.393), males (OR: 1.33, p = 0.639), non-urbanized regions (OR: 1.18, p = 0.594), low educational level (OR: 3.46, p = 0.222), and employed (OR: 1.34, p = 0.423), were more likely to have multiple infections. Our results demonstrate a high rate of circulation of STIs among blood donation candidates in Luanda. HBV was the main reason for the rejection of candidates. However, nucleic acid-based screening techniques should be considered to ensure better quality screening for occult infections in blood donor candidates.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04649-3
Sylvia Caldwell, Olivia Kirby, Tabor Flickinger, Gustavo Frietas, Karen Ingersoll, Amanda D. Castel, on behalf of the DC Cohort-PositiveLinks Study team
{"title":"Curating an HIV mHealth App for People Living with HIV in Washington, DC Through Think-Aloud Usability Testing and Beta Testing","authors":"Sylvia Caldwell, Olivia Kirby, Tabor Flickinger, Gustavo Frietas, Karen Ingersoll, Amanda D. Castel, on behalf of the DC Cohort-PositiveLinks Study team","doi":"10.1007/s10461-025-04649-3","DOIUrl":"10.1007/s10461-025-04649-3","url":null,"abstract":"<div><p>This study evaluated the usability of a mobile health application for persons with HIV (PWH) in the District of Columbia (DC) area in preparation for a pragmatic cluster randomized efficacy trial of the PositiveLinks (PL) app. Fourteen participants from the DC Cohort, a multi-site longitudinal prospective HIV cohort study, participated in Think-aloud usability testing. Participants viewed a demonstration version of the PL app and narrated their thoughts, impressions, navigation, and comments as they moved through the app functions. A second set of fourteen DC Cohort participants used the PL app for a one-month period of Beta testing to identify any bugs or glitches, then completed an in-depth interview and System Usability Survey (SUS). A majority of participants identified as male and non-Hispanic Black. Qualitative data from the Think-alouds and Beta testing interviews were audio recorded, transcribed and analyzed in Dedoose using an iterative approach. Think-aloud and Beta testing showed that users viewed the app positively and considered it to be user- friendly. Participants particularly liked the daily reminders and ability to communicate with peers with HIV and their HIV care team. Although most participants reported no dislikes, they requested more customization and more resources. The app achieved a high mean SUS score of 76 and high response rates for app features. No bugs or glitches were identified. The version of PL to be used by participants in the DC Cohort was well liked and highly usable, and participant input informed optimization of the app prior to launching the efficacy trial.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 6","pages":"1810 - 1820"},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04702-1
Adrian Albernas, Maitri D Patel, Robert L Cook, Krishna Vaddiparti, Mattia Prosperi, Yiyang Liu
{"title":"HIV Risk Score and Prediction Model in the United States: A Scoping Review.","authors":"Adrian Albernas, Maitri D Patel, Robert L Cook, Krishna Vaddiparti, Mattia Prosperi, Yiyang Liu","doi":"10.1007/s10461-025-04702-1","DOIUrl":"https://doi.org/10.1007/s10461-025-04702-1","url":null,"abstract":"<p><p>Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors and the performance of HIV risk prediction models. We analyzed 18 studies published since 2010, which featured logistic regression, survival analysis, and machine learning techniques. These studies focused on diverse populations, including men who have sex with men, emergency department visitors, and the general population. Key predictors of HIV risk included demographics (age, sex, race) and behavioral factors (sexual practices, drug use). Electronic health records (EHR) documenting diagnoses of sexually transmitted infection (STI) were significant in all models. Behaviors like condomless sex, multiple sexual partners, and drug use were also strongly linked to increased risk scores. However, we noted a lack of social determinants of health in risk models, and a gap in studies focusing on cis female and transgender populations.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04686-y
Hellen Babu, Stuart Gilmour, Mbilu Byron, Rhoda Kabuti, Festus K Muriuki, Jinghua Li, Junko Tanuma, Joshua Kimani
{"title":"Trends in HIV Incidence among Female Sex Workers and Men who Have Sex with Men in Nairobi, Kenya, 2009-2021.","authors":"Hellen Babu, Stuart Gilmour, Mbilu Byron, Rhoda Kabuti, Festus K Muriuki, Jinghua Li, Junko Tanuma, Joshua Kimani","doi":"10.1007/s10461-025-04686-y","DOIUrl":"https://doi.org/10.1007/s10461-025-04686-y","url":null,"abstract":"<p><p>Female Sex Workers (FSW) and men who have sex with men (MSM) in Kenya remained disproportionately burdened by HIV. Our study aims to estimate trends in HIV incidence and identify characteristics associated with the rate of infection among these populations over the past decade. Data were collected at Sex Workers Outreach Program (SWOP) in Nairobi County from 2009 to 2021. We included records of 3,595 FSW and 581 MSM with a negative HIV test at enrolment and at least one follow-up test. We compared survival time between MSM and FSW using the Kaplan Meier log-rank test and used multiple Poisson regression to estimate incidence rate ratios. A steady decline in HIV infection was observed from 2009 to 2019 but increased in 2020 and 2021. The crude incidence rate was 1.46 (95% CI: 1.29-1.65) cases per 100 person-years. The incidence rate among MSM was 8.08 (6.73-9.69) per 100 person-years and 0.8 (95% CI: 0.7-1.0) per 100 person-years of follow-up among the FSW. In multivariate analysis, MSM had 16.14 times the risk of HIV infection compared to FSW (95% CI: 9.20-28.32), with relative risk declining in older age groups until over 50, where MSM and FSW experienced similar risk. For every successive year since 2009, the risk of HIV infection declined (annual IRR:0.73, 95% CI: 0.71-0.75). Continued and accelerated efforts targeted at MSM and FSW are needed to ensure the observed decline in HIV incidence continues in line with the UNAIDS-2030 global targets.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04668-0
Robert A. Bonacci, Nivedha Panneer, Anne Marie France, Angela B. Hutchinson, Ram K. Shrestha, Md Hafizul Islam, Paul G. Farnham, Alexandra M. Oster
{"title":"Minimal Reduction in HIV Transmission Needed for HIV Cluster Detection and Response to be Cost Saving","authors":"Robert A. Bonacci, Nivedha Panneer, Anne Marie France, Angela B. Hutchinson, Ram K. Shrestha, Md Hafizul Islam, Paul G. Farnham, Alexandra M. Oster","doi":"10.1007/s10461-025-04668-0","DOIUrl":"10.1007/s10461-025-04668-0","url":null,"abstract":"<div><p>HIV cluster detection and response (CDR) provides a framework for identifying rapid HIV transmission and guiding implementation of proven HIV prevention and care strategies. Characterizing the relative benefits of CDR is important for guiding policy makers in resource allocation for HIV prevention. We sought to understand how many HIV infections would need to be averted by CDR activities to achieve various return-on-investment (ROI) thresholds. We conducted an ROI analysis of CDR in 2022, incorporating costs and benefits across US jurisdictions funded for HIV surveillance and prevention. Setting ROI thresholds between 1 and 5, we estimated the number of HIV infections that would need to be averted annually by CDR activities to reach ROI thresholds. A scenario was considered cost saving if the ROI > 1. Based on the number of people in national priority molecular clusters and estimated transmission in these clusters, we determined the percent reduction in transmission within these clusters that would be required to achieve the threshold number of HIV infections averted. The number of HIV infections needing to be averted annually ranged from 19 infections (ROI = 1) to 94 infections (ROI = 5). Among 657 HIV transmissions within national priority molecular clusters, the percent reduction in HIV transmission needed to meet ROI thresholds ranged from 2.9% (ROI = 1) to 14.3% (ROI = 5). In conclusion, CDR activities would need to avert a minimal number of HIV infections nationally to achieve cost savings.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 6","pages":"2016 - 2021"},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04696-w
Peter Meylakhs, Tatiana Rodionova, Arsen Davitadze, Alexey Lakhov, Ksenia Eritsian, Dmitry Kislitsyn, Daria Antonova, Roman Skochilov
{"title":"Two Drug Epidemics in St. Petersburg, Russia? Substance Use, Risk Behaviors, and HIV and HCV Prevalence Among Young and Older People Who Inject Drugs Attending a Harm Reduction Facility.","authors":"Peter Meylakhs, Tatiana Rodionova, Arsen Davitadze, Alexey Lakhov, Ksenia Eritsian, Dmitry Kislitsyn, Daria Antonova, Roman Skochilov","doi":"10.1007/s10461-025-04696-w","DOIUrl":"https://doi.org/10.1007/s10461-025-04696-w","url":null,"abstract":"<p><p>Russia has an estimated 1.3-1.8 million people who inject drugs (PWID). In recent years concomitant decline of opioid use and rise of new psychoactive substances (NPS) use was observed. We conducted secondary analysis of survey data collected in 2019-2021 by a harm reduction organization in Saint-Petersburg, Russia (n = 978). Older PWID group (30+) was significantly more likely to use opioids (87.5% vs. 32.4%) than young PWID; young PWID used NPS four times more frequently than older ones (79.9% vs. 21.5%). The odds ratio of being an exclusive stimulant user but not an opioid user among younger cohorts is more than forty-five times higher than among older cohorts all else being equal (AOR = 47.38; 95% CI 21.90-102.53; p < 0.001). The younger respondents were more than four times less likely to be HIV-positive than older participants (8.4% vs. 36.7%) and more than three times less likely to be HCV-positive (23.5% vs. 80.6%). Young PWID were significantly more prone to risk behaviors (syringes sharing in past month; having overdose in the last 12 months; and inconsistent condom use during past 3 months) than older PWID, which renders them vulnerable to rapid HIV and HCV transmission both by parenteral and sexual routes. It is possible that currently we are observing two epidemics- an \"old\" opioid epidemic among older generations of PWID and a new synthetic cathinones epidemic among younger generations of PWID. New forms of harm reduction tailored to the needs of NPS users along with expansion of existing harm reduction programs for opioid users are urgently needed.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04685-z
Tea Nynne Sanders, Anna Katrine Haslund Roed, Malene Missel, Selina Kikkenborg Berg, Susanne Dam Nielsen, Mette Linnet Olesen, Ole Kirk
{"title":"Barriers to Retention in Care among Adults with HIV in Developed Countries: An Integrative Review.","authors":"Tea Nynne Sanders, Anna Katrine Haslund Roed, Malene Missel, Selina Kikkenborg Berg, Susanne Dam Nielsen, Mette Linnet Olesen, Ole Kirk","doi":"10.1007/s10461-025-04685-z","DOIUrl":"https://doi.org/10.1007/s10461-025-04685-z","url":null,"abstract":"<p><p>Focusing on factors hindering viral suppression is essential for improving the health outcomes of people with Human Immunodeficiency Virus (HIV) and working towards ending the HIV/AIDS epidemic. The aim of this integrative review is to create an overview of barriers to retention in care among adults with HIV living in developed countries. Based on a systematic literature search across EMBASE, PubMed, Scopus, CINAHL, and PsycInfo, 4,089 studies of various methodology were identified. A total of 52 studies met the inclusion criteria. Quality assessment was performed using the Mixed Method Appraisal Tool. Based on thematic analysis, the following five main themes were identified as most common barriers to retention in care: financial challenges, logistical challenges, stigma, mental health problems, and substance use. The integrative review highlights that various factors can hinder retention in care and underscores that strategies to promote retention in care should be person-centered and targeted the individual person's barriers to retention in care.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04695-x
Mar J F Ollero, Pablo Ryan, Helen Dolengevich-Segal, Joanna Cano-Smith, Luis Ramos-Ruperto, Alfonso Cabello, Matilde Sanchez-Conde, Noemí Cabello, Jose Sanz, Lucio Jesus García-Fraile, Leire Perez-Latorre, Otilia Bisbal, Sara De La Fuente, Juan Emilio Losa, Alicia González-Baeza
{"title":"Drug Addiction in Gay and Bisexual Men Living with HIV Engaged in Sexualized Drug Use: Recent Drug Use, Polydrug and Depressive Symptoms as Predictors.","authors":"Mar J F Ollero, Pablo Ryan, Helen Dolengevich-Segal, Joanna Cano-Smith, Luis Ramos-Ruperto, Alfonso Cabello, Matilde Sanchez-Conde, Noemí Cabello, Jose Sanz, Lucio Jesus García-Fraile, Leire Perez-Latorre, Otilia Bisbal, Sara De La Fuente, Juan Emilio Losa, Alicia González-Baeza","doi":"10.1007/s10461-025-04695-x","DOIUrl":"https://doi.org/10.1007/s10461-025-04695-x","url":null,"abstract":"<p><p>Evidence shows that engaging in sexualized drug use (SDU) can be associated with sexual health problems and poor mental health. However, the prevalence of drug-related problems associated with SDU remains unclear. Our study aimed to examine the prevalence and associated factors of drug-related problems and drug dependence in a sample of gay, bisexual, and other men who have sex with men living with HIV (HIV + GBMSM). We included 101 HIV + GBMSM who had engaged in SDU in the last year. Participants completed an online survey featuring a validated questionnaire (the DUDIT test) to assess the risk of drug-related problems and drug dependence. Univariate and multivariate analyses were conducted to explore variables associated with drug-related problems. 80% of our sample had symptoms suggestive of drug-related problems, with 5% showing likely drug dependence. Additionally, 10% had suffered an overdose with loss of consciousness, 9% experienced suicidal thoughts associated with SDU, and approximately 20% had sexual difficulties during sober sex since using drugs for sex. Multivariate analysis identified that recent drug use (less than 15 days prior), polydrug use, and depressive symptoms are independent predictors of drug-related problems. Our study revealed a high prevalence of drug-related problems among HIV + GBMSM engaged in SDU. The factors associated with drug-related problems identified in our study can serve as key markers in clinical settings where HIV + GBMSM receive care. These indicators can help detect community members most at risk and facilitate the provision of resources and interventions to prevent SDU-related harm.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AIDS and BehaviorPub Date : 2025-04-05DOI: 10.1007/s10461-025-04673-3
Paul C J Berthe, Yanis Ben Amor
{"title":"A Rapid Review of HIV-Related Stigma-Reduction Randomized Controlled Trials.","authors":"Paul C J Berthe, Yanis Ben Amor","doi":"10.1007/s10461-025-04673-3","DOIUrl":"https://doi.org/10.1007/s10461-025-04673-3","url":null,"abstract":"<p><p>We conducted a rapid review to identify and describe randomized controlled trials (RCTs) aimed at reducing HIV-related stigma. Using a rapid review design in accordance with PRISMA guidelines, we searched five major databases (PubMed, PsycINFO, OVID/Medline, EMBASE, and Scopus) from July 1981 to June 2023, and analyzed 27 studies from an initial pool of 2,383 articles. Our analysis revealed three primary intervention strategies: (1) alleviating internalized stigma through confidence-building and emotional validation, (2) addressing anticipated and enacted stigma via training and sensitization campaigns, and (3) challenging institutional and cultural beliefs through macro-scale interventions. Community-driven approaches and locally-engaged interventions demonstrated particular promise, especially in resource-constrained settings. While intrapersonal and interpersonal approaches-particularly those involving professional discussions, peer education, and in-person training-showed the most positive outcomes, digital and infotainment interventions yielded mixed results. Our findings highlight the complexity of HIV-related stigma, revealing the importance of holistic strategies that address intersecting psychosocial factors and potential unintended consequences of stigma-reduction efforts. By studying the nuanced landscape of stigma intervention, this review provides insights for developing more comprehensive and contextually sensitive approaches to reducing HIV-related stigma.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}