AIDS and Behavior最新文献_第6页

Pain Severity and Experiences with Pain Management Predict Alcohol Use Among Men Who Have Sex with Men Living with HIV.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04652-8

Erin Ferguson, David W Pantalone, Peter M Monti, Kenneth H Mayer, Christopher W Kahler

{"title":"Pain Severity and Experiences with Pain Management Predict Alcohol Use Among Men Who Have Sex with Men Living with HIV.","authors":"Erin Ferguson, David W Pantalone, Peter M Monti, Kenneth H Mayer, Christopher W Kahler","doi":"10.1007/s10461-025-04652-8","DOIUrl":"https://doi.org/10.1007/s10461-025-04652-8","url":null,"abstract":"Unhealthy alcohol use is prevalent among people with HIV, particularly among men who have sex with men (MSM). Pain frequently co-occurs with unhealthy alcohol use and is associated with suboptimal HIV care outcomes. The present study examined the effects of pain severity and experiences with pain management care (i.e., satisfied, dissatisfied, managing pain on own) on alcohol use. Participants were MSM with HIV reporting heavy alcohol use and pain in the past 30 days who were enrolled in a clinical trial targeting alcohol use (N = 125, 78.4% White, Mage=41.2). Participants completed measures of unhealthy alcohol use [alcohol-related problems, heavy drinking days, drinks per week, drinking to manage pain (yes/no)], pain severity, and pain management care experiences. An analysis of variance examined differences in pain severity by pain management experience. Regression analyses examined the associations of pain severity and pain management experience with unhealthy alcohol use. Pain severity was significantly associated with drinking to manage pain and heavy drinking days, but not drinks per week or alcohol-related problems. MSM with HIV who were dissatisfied with pain care reported significantly greater pain severity compared to those who were satisfied or managing pain on their own. Compared to satisfaction, dissatisfaction with pain care was also associated with significantly higher odds of drinking to manage pain, although the inclusion of pain severity attenuated this association. Results highlight pain severity as a key factor related to pain management experience and unhealthy alcohol use among MSM with HIV. Future studies should prioritize pain-alcohol integrated intervention development.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of COVID-19-Related Disruptions on Antiretroviral Therapy Adherence Among Young Adults Living with HIV in Southern Uganda.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04634-w

Abel Zemedkun Girma, Rachel Brathwaite, Yvonne Karamagi, Fatumah Nakabuye, Noeline Nakasujja, William Byansi, Proscovia Nabunya, Ozge Sensoy Bahar, Fred M Ssewamala

{"title":"Impact of COVID-19-Related Disruptions on Antiretroviral Therapy Adherence Among Young Adults Living with HIV in Southern Uganda.","authors":"Abel Zemedkun Girma, Rachel Brathwaite, Yvonne Karamagi, Fatumah Nakabuye, Noeline Nakasujja, William Byansi, Proscovia Nabunya, Ozge Sensoy Bahar, Fred M Ssewamala","doi":"10.1007/s10461-025-04634-w","DOIUrl":"https://doi.org/10.1007/s10461-025-04634-w","url":null,"abstract":"We investigated how COVID-19-related disruptions influenced antiretroviral therapy (ART) adherence among young adults living with HIV (YALHIV) in Southern Uganda, a region with limited resources and high rates of HIV. Data were analyzed from 499 YALHIV aged 19 to 25, participating in the Suubi+Adherence-R2 COVID-19 Supplement study. The study measured COVID-19 disruptions using an 8-item Coronavirus Impact Scale and evaluated ART adherence through self-reported measures. Our analytical framework was informed by the Health Belief Model and generalized estimating equations were estimated. We find no statistically significant association between COVID-19 disruptions, as quantified by the COVID-19 Impact Score, and sub-optimal ART adherence (OR = 0.99, 95% CI [0.87-1.14]). However, findings revealed that being employed (OR = 1.99, 95% CI [1.07-3.71]) and older age (OR = 1.18, 95% CI [1.02-1.37]) was associated with higher likelihood of poor adherence highlighting the complex interplay between economic activity, working schedules, and health management. Other notable predictors included marital status, with cohabiting individuals showing decreased odds of poor adherence (OR = 0.25, 95% CI [0.08-0.74]) compared to single and separated YALHIV. These insights emphasize the need for multifaceted intervention strategies that consider both individual and systemic factors affecting ART adherence. Tailored interventions must address the socioeconomic challenges intensified by the pandemic and leverage the inherent resilience within this population to enhance ART adherence outcomes for YALHIV in challenging environments. Trial Registration ClinicalTrials.gov, ID: NCT01790373.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Peer Referral on Pre-Exposure Prophylaxis Adherence and Persistence Among Men Who Have Sex with Men: A Cohort Study in China.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-025-04651-9

Chengxin Fan, Zhuoheng Yin, Chunyan Li, Yifan Dai, Heping Zhao, Gifty Marley, Quanmin Li, Songjie Wu, Haojie Huang, Aniruddha Hazra, Jonathan Lio, Ke Liang, Linghua Li, Renslow Sherer, Joseph D Tucker, Weiming Tang

{"title":"Impact of Peer Referral on Pre-Exposure Prophylaxis Adherence and Persistence Among Men Who Have Sex with Men: A Cohort Study in China.","authors":"Chengxin Fan, Zhuoheng Yin, Chunyan Li, Yifan Dai, Heping Zhao, Gifty Marley, Quanmin Li, Songjie Wu, Haojie Huang, Aniruddha Hazra, Jonathan Lio, Ke Liang, Linghua Li, Renslow Sherer, Joseph D Tucker, Weiming Tang","doi":"10.1007/s10461-025-04651-9","DOIUrl":"https://doi.org/10.1007/s10461-025-04651-9","url":null,"abstract":"Peer referral leverages social networks to connect individuals with health services, potentially enhancing pre-exposure prophylaxis (PrEP) use. This study aims to investigate the impact of peer referral on PrEP adherence and persistence among men who have sex with men (MSM) in China. This study is nested in a 12-month PrEP (FTC/TDF) demonstration trial in China from September 2021 to December 2023. Peer referral was defined as participants being referred by peers already enrolled in the trial. PrEP adherence was measured as taking four or more pills per week for daily users or following the 2 + 1 + 1 event-driven regimen at least 75% of the time. PrEP persistence was defined as the time from initiation to discontinuation. We collected data from the first 6 months of follow-up and used generalized estimating equations and Cox regression models to evaluate the association between peer referral and PrEP adherence and persistence. A total of 1,131 MSM initiated PrEP, with 121 (10.7%) referred by peers. At month 6, adherence rates were 75.0% for peer-referred MSM and 67.1% for non-peer-referred MSM. Peer-referred MSM had higher adherence than non-peer-referred MSM (aRR = 1.11, 95% CI: 1.01-1.22). Regarding persistence, 812 (71.8%) MSM continued using PrEP at 6 months of follow-up, and peer-referred MSM were more likely to persist with PrEP (aHR = 1.85, 95% CI: 1.17-2.91). These findings demonstrate the potential of peer referral in promoting PrEP use among MSM, suggesting the value of powerful peer-based interventions like peer navigation in future PrEP outreach.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facilitators and Barriers to Hiv Pre-Exposure Prophylaxis Adherence and Retention Among Young Men Who have Sex With Men: A Meta-Ethnographic Scoping Review.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-10 DOI: 10.1007/s10461-024-04582-x

Le Anh Tuan, Loc Quang Pham, Tong Thi Khuyen, Bui Minh Hao, Nguyen Thi Phuong Hoa, Kim-Duy Vu, Tran Hoang My Lien, Pham Thi Thanh Duyen, Hai Thanh Phan, Le Minh Giang, Sophia M Bartels, Sarah E Rutstein

{"title":"Facilitators and Barriers to Hiv Pre-Exposure Prophylaxis Adherence and Retention Among Young Men Who have Sex With Men: A Meta-Ethnographic Scoping Review.","authors":"Le Anh Tuan, Loc Quang Pham, Tong Thi Khuyen, Bui Minh Hao, Nguyen Thi Phuong Hoa, Kim-Duy Vu, Tran Hoang My Lien, Pham Thi Thanh Duyen, Hai Thanh Phan, Le Minh Giang, Sophia M Bartels, Sarah E Rutstein","doi":"10.1007/s10461-024-04582-x","DOIUrl":"https://doi.org/10.1007/s10461-024-04582-x","url":null,"abstract":"Retention and adherence to daily oral pre-exposure prophylaxis (PrEP) are critical for effective HIV prevention; however, YMSM exhibit lower rates of both compared to other populations. This is important because young men who have sex with men (YMSM) are at higher risk for HIV, and understanding their challenges can help create better support and interventions. This scoping review synthesizes evidence on the facilitators and barriers to HIV PrEP retention and adherence among YMSM, focusing on individuals aged 10 to 29 years. The review adheres to PRISMA-ScR and eMERGe guidelines, examining 14 studies involving 3,178 participants. It emphasizes the complex interactions of individual, interpersonal, community, and societal factors influencing PrEP adherence and retention. Key facilitators include psychological strategies, supportive health systems, and supportive social networks. Conversely, significant barriers encompass financial burdens, interpersonal stigma, and behavioral factors. The review highlights the critical role of tailored, multi-level interventions and the need for healthcare provider training in youth-specific approaches to care. This work contributes to a nuanced understanding of PrEP retention among YMSM, offering insights crucial for designing effective public health strategies to enhance prevention-effective PrEP utilization in this high-risk population.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying Subgroups of Intersectional Stigma, Discrimination, and the Association with Mental Health Outcomes Among HIV-Positive Men Who Have Sex with Men: A Latent Class Analysis

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-04 DOI: 10.1007/s10461-024-04583-w

Liying Wang, Kathy Trang, Casey Xavier Hall, Lin Zhu, R. N. Eugenia Millender, Crim Sabuncu, Jack Barile, Grace Ma, Avrum Gillespie, Gina Simoncini, Frankie Wong

{"title":"Identifying Subgroups of Intersectional Stigma, Discrimination, and the Association with Mental Health Outcomes Among HIV-Positive Men Who Have Sex with Men: A Latent Class Analysis","authors":"Liying Wang, Kathy Trang, Casey Xavier Hall, Lin Zhu, R. N. Eugenia Millender, Crim Sabuncu, Jack Barile, Grace Ma, Avrum Gillespie, Gina Simoncini, Frankie Wong","doi":"10.1007/s10461-024-04583-w","DOIUrl":"10.1007/s10461-024-04583-w","url":null,"abstract":"<div>This study aimed to (1) identify latent classes of stigma and discrimination experiences among men who have sex with men (MSM) living with HIV; (2) examine the associations between class membership and mental health outcomes, and (3) investigate the moderating effects of social support and resilience. The study used the baseline (N = 224) and six-month follow-up data (N = 118) from a longitudinal cohort study on HIV and hypertension among African American and Asian Pacific American MSM in Hawai’i and Philadelphia from 2019 to 2023. Latent class analysis was conducted to characterize the patterns of stigma and discrimination experience. Multivariable regression was conducted to examine the association between class membership and mental health outcomes. Interaction terms were added to examine the moderation effects of social support and resilience on the association between class memberships and mental health outcomes. A five-class model was identified: Class (1) high on internalized homophobia and low on all discrimination experiences; Class (2) high on racial discrimination; Class (3) high on sexual identity discrimination; Class (4) low on internalized homophobia and all discrimination experiences; Class (5) high on physical disability discrimination and internalized homophobia. Class 5 consistently predicted worse mental health outcomes, compared to Class 4. The association between Class 2 (high racial discrimination) and depression was moderated by perceived social support. The study reveals complex experiences of intersectional stigma and discrimination among MSM living with HIV, highlighting the need for further research on the intersecting effects of multiple disadvantages among aging sexual minorities.</div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 3","pages":"1011 - 1027"},"PeriodicalIF":2.7,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socio-ecological Determinants of Detectable Viremia among Pregnant People Living with HIV in South Brazil: The Role of Stimulant Use Disorder and Homelessness.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04639-5

Christopher Justin Hernandez, Fernando Echegaray, Kavya Sundar, Lanbo Z Yang, Mary Catherine Cambou, Eddy R Segura, Marineide Gonçalves de Melo, Breno Riegel Santos, Ivana Rosângela Dos Santos Varella, Karin Nielsen-Saines

{"title":"Socio-ecological Determinants of Detectable Viremia among Pregnant People Living with HIV in South Brazil: The Role of Stimulant Use Disorder and Homelessness.","authors":"Christopher Justin Hernandez, Fernando Echegaray, Kavya Sundar, Lanbo Z Yang, Mary Catherine Cambou, Eddy R Segura, Marineide Gonçalves de Melo, Breno Riegel Santos, Ivana Rosângela Dos Santos Varella, Karin Nielsen-Saines","doi":"10.1007/s10461-025-04639-5","DOIUrl":"10.1007/s10461-025-04639-5","url":null,"abstract":"Pregnant patients living with HIV are a priority group for the recruitment into the HIV healthcare cascade to prevent adverse maternal and neonatal health outcomes. Understanding the structural, interpersonal, and individual factors that are associated with detectable HIV viremia is of importance to guide outreach and intervention priorities. This was a retrospective cohort study of pregnant patients living with HIV who delivered from January 1, 2017, to December 31, 2023, at a tertiary-level hospital and referral institution for HIV care in Porto Alegre, Brazil. The socio-ecological model was used to guide hypothesis testing regarding associations with detectable viremia. In total, 549 patients were included, of whom 110 (20%) were found to have detectable viremia. Significant differences between detectable and undetectable viremia included prenatal care, homelessness, having a sero-different partner, and stimulant use. Multivariable associations included prenatal care (adjusted Risk Ratio [aRR] = 0.20, 95% Confidence Interval [95% CI] = 0.15-0.26), homelessness (aRR = 4.02, 95% CI = 2.74-0.26), stimulant use disorder (aRR = 3.30, 95% CI = 2.23-4.87), crack use (aRR = 2.82, 95% CI = 1.85-4.29), and cocaine use (aRR = 1.89, 95% CI = 1.17-3.06). Intervention research should focus on housing and mental health services, and how to mitigate their impact on HIV healthcare. Intervention research is greatly needed as current tools may not be sufficient to tackle the issue of stimulant use disorder and its effects on ART adherence.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measuring Implementation Outcomes Change Over Time Using an Adapted Checklist for Assessing Readiness to Implement (CARI).

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04614-0

Beth Bourdeau, Mary A Guzé, Greg M Rebchook, Starley B Shade, Demetrios Psihopaidas, Nicole S Chavis, Janet J Myers

{"title":"Measuring Implementation Outcomes Change Over Time Using an Adapted Checklist for Assessing Readiness to Implement (CARI).","authors":"Beth Bourdeau, Mary A Guzé, Greg M Rebchook, Starley B Shade, Demetrios Psihopaidas, Nicole S Chavis, Janet J Myers","doi":"10.1007/s10461-025-04614-0","DOIUrl":"https://doi.org/10.1007/s10461-025-04614-0","url":null,"abstract":"In 2017, the Health Resources and Services Administration's HIV/AIDS Bureau funded an Evaluation Center (EC) to assess the rapid implementation of 11 evidence-informed interventions at 25 HIV care and treatment providers across the U.S. The EC conducted an implementation science-based evaluation, including longitudinal assessment of implementation outcomes as defined by Implementation Outcome Framework (IOF) of the Conceptual Model for Implementation Research. The EC adapted a measure originally designed for implementation readiness to capture seven implementation outcomes and administered the measure to site leadership every six months, from intervention launch through the end of the initiative. The adapted measure demonstrated adequate internal consistency within and across time periods. Individual outcomes changed over the course of implementation, with the greatest period of growth during the first six months. Longitudinal relationships between outcomes posited to be most relevant at early, mid- or late-implementation were not evident in these analyses; rather, relationships between the outcomes were significant within time periods. Finally, there were differences in the trajectory of outcomes based on characteristics of the site's larger context. The use of this adapted measure across multiple implementation settings, assessing multiple interventions, is an important step forward in the comparability of implementation outcomes more broadly.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PrEP Awareness, Interest, and Use among Women Who Inject Drugs in Seattle, Washington: A Mixed Methods Study.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04646-6

Lauren R Violette, Maria A Corcorran, Elizabeth J Austin, Emily C Williams, Sara N Glick, Shireesha Dhanireddy, Jenell Stewart

{"title":"PrEP Awareness, Interest, and Use among Women Who Inject Drugs in Seattle, Washington: A Mixed Methods Study.","authors":"Lauren R Violette, Maria A Corcorran, Elizabeth J Austin, Emily C Williams, Sara N Glick, Shireesha Dhanireddy, Jenell Stewart","doi":"10.1007/s10461-025-04646-6","DOIUrl":"10.1007/s10461-025-04646-6","url":null,"abstract":"Women who inject drugs (WWID) are disproportionately affected by HIV and experience multiple barriers to PrEP use. We conducted a mixed methods study to assess PrEP awareness, interest, and use, and determinants of PrEP utilization among WWID at three community sites in Seattle, Washington from March-May 2023. Participants were ≥ 18 years old, spoke English, identified as women, had a history of injecting drugs, and self-reported a negative or unknown HIV status. We describe survey participant characteristics (n = 30) by PrEP candidacy based on behaviors associated with HIV acquisition. We concurrently recruited 16 WWID for semi-structured interviews, which were analyzed using the Rapid Assessment Process. Survey and interview data were triangulated to enhance interpretations. Among 30 WWID, 25 (83%) were PrEP candidates, of whom 19 (76%) had heard about PrEP; only 2 (8%) were currently using PrEP. Among PrEP candidates, 13 (57%) reported interest in daily oral PrEP and almost half (n = 12, 48%) reported interest in injectable PrEP. Qualitative data revealed cursory PrEP knowledge and a strong interest in daily oral and injectable PrEP among those who perceived they were at risk for HIV. Several barriers to PrEP use were noted including housing instability, adherence challenges, limited perceived risk, and competing priorities like safety and substance use. While most WWID were aware of PrEP, qualitative data suggested significant misconceptions about PrEP, and many described complex, intersecting barriers to use. Our findings highlight the need for increased low-barrier, population-specific interventions to improve uptake and sustained use of PrEP among WWID.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pilot Trial of a Transdiagnostic Cognitive Behavioral Therapy (CBT)-Based Group Intervention to Reduce Psychological Distress, Facilitate Positive Behavior Change, and Mitigate Inflammation in Older People with HIV.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04647-5

Jacklyn D Foley, Madison Davis, Stephanie Schiavo, Lauren Bernier, Shibani S Mukerji, Abigail W Batchelder

{"title":"Pilot Trial of a Transdiagnostic Cognitive Behavioral Therapy (CBT)-Based Group Intervention to Reduce Psychological Distress, Facilitate Positive Behavior Change, and Mitigate Inflammation in Older People with HIV.","authors":"Jacklyn D Foley, Madison Davis, Stephanie Schiavo, Lauren Bernier, Shibani S Mukerji, Abigail W Batchelder","doi":"10.1007/s10461-025-04647-5","DOIUrl":"https://doi.org/10.1007/s10461-025-04647-5","url":null,"abstract":"More than half of adults with HIV in the United States are aged 50 or older. Older people with HIV (OPWH) are disproportionately affected by age-related health disparities and non-communicable diseases associated with inflammation. The current pilot randomized controlled trial (RCT) evaluated the feasibility and acceptability, while exploring signals of effects of a transdiagnostic cognitive behavioral therapy (CBT) modular group teaching skills to cope with distress, make positive health behavior changes, and ultimately reduce inflammation. Participants were 31 virally undetectable, and psychiatrically stable OPWH (age [Formula: see text]50 years). Participants were randomized 1:1 to enhanced usual care or CBT for HIV and Symptom Management (CHAMP). CHAMP consists of 12-weekly virtual group sessions led by two interventionists. Self-report questionnaires and intravenous blood draws were collected at baseline and follow-up. Intervention participants completed an exit interview. Of those screened eligible, 96.8% (30/31) were randomized (n = 15 per group), 86.7% (13/15) completed the intervention, and 87% (26/30) completed the follow-up. On acceptability questionnaires scaled 0-3, participants reported high satisfaction and the intervention to be of high quality (M(SD)=3.00(0.0) for both). They also indicated their needs were met (2.67(0.50)) and coping improved (2.60(0.52)). Intervention participants showed a mean decrease in anxiety (-1.07(6.08)) and depressive (-1.71(5.37)) symptoms on clinical screeners, and mean increase in quality of life (2.86(3.59)). CHAMP is both feasible and acceptable for OPWH. Exploratory analyses indicate favorable outcomes for improving psychological distress and health-related quality of life.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-Term Mobility and Risky Sexual Behaviors Among Men Who Have Sex with Men in Guangdong, China.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-02-03 DOI: 10.1007/s10461-025-04629-7

Mengting Liu, Xinran Jiang, Jun Liu, Shilan Xie, Bo Zhang, Tiantian Fu, Zhikang Li, Yongheng Lu, Jie Lu, Fang Yang, Xiaobing Fu, Jinghua Li

{"title":"Short-Term Mobility and Risky Sexual Behaviors Among Men Who Have Sex with Men in Guangdong, China.","authors":"Mengting Liu, Xinran Jiang, Jun Liu, Shilan Xie, Bo Zhang, Tiantian Fu, Zhikang Li, Yongheng Lu, Jie Lu, Fang Yang, Xiaobing Fu, Jinghua Li","doi":"10.1007/s10461-025-04629-7","DOIUrl":"https://doi.org/10.1007/s10461-025-04629-7","url":null,"abstract":"This study investigated regional differences in short-term mobility patterns among men who have sex with men (MSM) in Guangdong Province, and explored the associations with risky sexual behaviors. An online survey was conducted from June to August 2023, collecting socio-demographic information, intra-provincial mobility details and sexual behaviors. Among 1,808 participants, 60% reported moving within the province over the past six months, primarily for tourism, business/work, or visiting family and friends. Participants were categorized into Pearl River Delta (PRD) and Non-Pearl River Delta (Non-PRD) regions. Significant differences in education level and income were observed between mobile and non-mobile MSM in both areas (p < 0.05). Logistic regression revealed that mobile MSM, relative to non-mobile MSM, were more likely to engage in risky sexual behaviors, with adjusted odds ratios (aORs) for multiple partners, commercial sex, and sexualized drug use ranging from 1.44 to 2.96 in PRD and 2.67 to 4.44 in Non-PRD. Additionally, associations between mobility and behaviors such as having casual partners, group sex, and inconsistent condom use with casual partners were exclusively identified in Non-PRD. These findings indicate that mobility among MSM in Guangdong Province is substantial and follows similar patterns in both regions. Mobile MSM exhibit higher rates of risky sexual behaviors, with notable regional disparities. Addressing the impact of short-term mobility on risky sexual behaviors among MSM is crucial, considering regional variations.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143078401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0