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Feasibility and Acceptability of the Sense2Quit App for Improving Smoking Cessation in PWH. Sense2Quit应用程序改善PWH患者戒烟的可行性和可接受性
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-25 DOI: 10.1007/s10461-025-04659-1
Rebecca Schnall, Ming-Chun Huang, Maeve Brin, Patricia A Cioe, Jianfang Liu, Anargya Das, Sydney Fontalvo, Wenyao Xu
{"title":"Feasibility and Acceptability of the Sense2Quit App for Improving Smoking Cessation in PWH.","authors":"Rebecca Schnall, Ming-Chun Huang, Maeve Brin, Patricia A Cioe, Jianfang Liu, Anargya Das, Sydney Fontalvo, Wenyao Xu","doi":"10.1007/s10461-025-04659-1","DOIUrl":"10.1007/s10461-025-04659-1","url":null,"abstract":"<p><p>An estimated 34-47% of PWH in the US report cigarette smoking, three to four times the prevalence observed in the U.S. adult population. Given the dearth of smoking cessation interventions for PWH, our study team used community based participatory feedback to design and develop the Sense2Quit App, an mHealth app linked to a smartwatch, whose sensor technology provides for collection of hand gesture movements to detect when a participant lifts their hand to smoke a cigarette. Participants receive messages through the app to encourage their quit attempts and maintenance of smoking cessation. The goal of this feasibility study was to conduct a randomized feasibility study in 60 PWH living in NYC to assess the feasibility and acceptability of the Sense2Quit App for smoking cessation. Findings from this study suggest that the intervention was highly feasible and acceptable in this population. There was high acceptability with only 1 participant withdrawing from the trial and overall app usage increasing over the course of the study. Participants wore the sensor and used the app and rated it as highly usable. The high retention rate and engagement with the app supports the overall acceptability of this approach. ClinicalTrials.gov Identifier: NCT05609032.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posttraumatic Stress Symptoms and HIV Risk-Related Behaviors among Young Sexual and Gender Minorities Assigned Male at Birth: the Moderating Effects of Teenage Childhood Sexual Abuse. 性和性别少数群体出生时被指定为男性的创伤后应激症状和艾滋病毒风险相关行为:青少年儿童期性虐待的调节作用
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-25 DOI: 10.1007/s10461-025-04661-7
Anthony E Hitch, Emils Sietins, Brian Mustanski, Michael E Newcomb
{"title":"Posttraumatic Stress Symptoms and HIV Risk-Related Behaviors among Young Sexual and Gender Minorities Assigned Male at Birth: the Moderating Effects of Teenage Childhood Sexual Abuse.","authors":"Anthony E Hitch, Emils Sietins, Brian Mustanski, Michael E Newcomb","doi":"10.1007/s10461-025-04661-7","DOIUrl":"https://doi.org/10.1007/s10461-025-04661-7","url":null,"abstract":"<p><p>Young sexual and gender minorities assigned male at birth (SGM-AMAB) experience significant sexual health disparities. Teenage childhood sexual abuse (CSA) may have lasting effects on adulthood trauma response, including engagement in HIV-related risk behaviors (HRB). This study examined the moderating effects of teenage CSA on the longitudinal associations between posttraumatic symptom clusters and HRB among young SGM-AMAB. The analytic sample comprised SGM-AMAB (N = 487) living in the Chicago metropolitan area, aged 17-32 (M = 24.78) enrolled in the RADAR longitudinal cohort study. Structural equation models (SEM) using Bayes estimation with 10,000 iterations were estimated to examine the moderating effects of any CSA exposure and severity indices (e.g., touching, penetration) on the associations between posttraumatic symptom clusters at Time 1 (T1) and HRB at Time 2 (T2) 6-month follow-up. Model fit was acceptable, χ<sup>2</sup> (df = 164) = 450.15, p <.001, RMSEA = 0.06, SRMR = 0.04, CFI = 0.93, TLI = 0.92. Avoidance at T1 predicted fewer condomless sex partners at T2 across CSA models. We observed 15 interaction effects across CSA models and outcomes. The moderating effects of both any CSA (β = 0.20, 95% CI = 0.02 - 0.38) and penetration CSA (β = 0.34, 95% CI = 0.14 - 0.55) changed the direction of the direct effect of avoidance on condomless sex partners, such that avoidance symptoms predicted more condomless sex partners among those with these CSA histories. This study observed patterns of association by posttraumatic symptom cluster, CSA index, and HRB outcome. Future directions and clinical implications are discussed.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Sexual Orientation Disclosure to Parents on Sexual Risk Behaviors and HIV Infection in Chinese Gay Men: A 15-Year Longitudinal Case-Control Study. 向父母披露性取向对中国男同性恋者性危险行为和HIV感染的影响:一项15年的纵向病例对照研究
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-22 DOI: 10.1007/s10461-025-04665-3
Yong Yu, Zheng Ren, Shishi Tang
{"title":"Impact of Sexual Orientation Disclosure to Parents on Sexual Risk Behaviors and HIV Infection in Chinese Gay Men: A 15-Year Longitudinal Case-Control Study.","authors":"Yong Yu, Zheng Ren, Shishi Tang","doi":"10.1007/s10461-025-04665-3","DOIUrl":"https://doi.org/10.1007/s10461-025-04665-3","url":null,"abstract":"<p><p>Sexual orientation disclosure has been shown to be associated with sexual risk behaviors (SRBs) and HIV infection among gay men. However, most previous studies are based on a cross-sectional design without a control group and do not distinguish between the subjects of disclosure. This study aimed to explore the impact of sexual orientation disclosure to parents on SRBs and HIV infection over 15 years. We conducted a longitudinal case-control study with 648 gay men who disclosed their sexual orientation to their parents and 648 who did not, all from Changsha, China. Data were collected at baseline in 2009 and at follow-up in 2024, focusing on five types of SRBs and HIV infection status. Generalized linear models were used to assess the impact of disclosure at baseline on SRBs and HIV infection at follow-up. The results showed that the disclosure group was less likely to have SRBs, including CAS (Risk Ratio [RR]: 0.61, 95% Confidence Interval [CI] 0.51-0.73), multiple concurrent sexual partners (RR: 0.74, 95% CI 0.62-0.88), group sex (RR: 0.64, 95% CI 0.51-0.81), chemsex (RR: 0.71, 95% CI 0.52-0.96), and commercial sex (RR: 0.54, 95% CI 0.42-0.70). They were also less likely to be infected with HIV (RR: 0.78, 95% CI 0.64-0.94). The study underscores the importance of sexual orientation disclosure in reducing the risk of SRBs and HIV infection among gay men, with significant implications for informing future public health policies and interventions for HIV prevention.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Social Network Theory-Based Investigation into the Characteristics of MSM in Virtual Communities. 基于社会网络理论的虚拟社区男男性行为特征研究。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-19 DOI: 10.1007/s10461-025-04657-3
Qiwei Ge, Xuan Shi, Hao Huang, Ziyue Zhou, Xiaoyi Zhou, Zijun Ni, Zixiao Zhou, Congxia Wu, Xun Zhuang
{"title":"A Social Network Theory-Based Investigation into the Characteristics of MSM in Virtual Communities.","authors":"Qiwei Ge, Xuan Shi, Hao Huang, Ziyue Zhou, Xiaoyi Zhou, Zijun Ni, Zixiao Zhou, Congxia Wu, Xun Zhuang","doi":"10.1007/s10461-025-04657-3","DOIUrl":"https://doi.org/10.1007/s10461-025-04657-3","url":null,"abstract":"<p><p>Social networks significantly influence MSM's HIV prevention behaviors, with virtual communities serving as key interaction platforms. Using a Python web crawler, we analyzed 960 user profiles from Baidu Tieba's \"Gay Bar\" forum. The social network within this community exhibits a core-periphery structure, where a densely connected core facilitates effective information dissemination, while the majority of users reside in peripheral positions with limited and isolated connections. Relationships within the network are primarily formed based on shared interests rather than geographical proximity, fostering homophilous interactions that enhance peer support and community cohesion. Despite the fragmented nature of peripheral connections, the tightly knit core enables the strategic targeting of key individuals to optimize the spread of health-related information and interventions. These findings highlight the importance of leveraging the network's core structure to implement efficient and inclusive public health strategies, ensuring that resources reach all members of the MSM community effectively. In addition, interest-based connections are essential in promoting a fair and supportive virtual environment, which is essential to address stigma and promote broad participation in HIV prevention.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: A Risk Prediction Model to Identify People Living with HIV Who are High-risk for Disengagement from Care after HIV Diagnosis in South Africa. 更正:一种风险预测模型,用于识别南非艾滋病病毒诊断后脱离护理的高危艾滋病毒感染者。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-19 DOI: 10.1007/s10461-025-04618-w
Ibrahima Dieye, Hallee Wong, Margeret McNairy, Hari Iyer, Gugulethu Tshabalala, Amanda Fata, Jacob Bor, Serena P Koenig, Kennedy Otwombe, Ingrid T Katz
{"title":"Correction: A Risk Prediction Model to Identify People Living with HIV Who are High-risk for Disengagement from Care after HIV Diagnosis in South Africa.","authors":"Ibrahima Dieye, Hallee Wong, Margeret McNairy, Hari Iyer, Gugulethu Tshabalala, Amanda Fata, Jacob Bor, Serena P Koenig, Kennedy Otwombe, Ingrid T Katz","doi":"10.1007/s10461-025-04618-w","DOIUrl":"https://doi.org/10.1007/s10461-025-04618-w","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Depression and HIV Symptoms on Glycemic Outcomes among Patients with HIV and Type 2 Diabetes: A Clinical Cohort Study. 抑郁和HIV症状对HIV合并2型糖尿病患者血糖结局的影响:一项临床队列研究
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-17 DOI: 10.1007/s10461-025-04653-7
Veronica Joyce Brady, Amanda L Willig, Katerina A Christopoulos, David J Grelotti, George A Yendewa, Conall O'Cleirigh, Richard D Moore, Sonia Napravnik, Allison Webel, Heidi M Crane, Michael S Saag, Stephanie A Ruderman
{"title":"Impact of Depression and HIV Symptoms on Glycemic Outcomes among Patients with HIV and Type 2 Diabetes: A Clinical Cohort Study.","authors":"Veronica Joyce Brady, Amanda L Willig, Katerina A Christopoulos, David J Grelotti, George A Yendewa, Conall O'Cleirigh, Richard D Moore, Sonia Napravnik, Allison Webel, Heidi M Crane, Michael S Saag, Stephanie A Ruderman","doi":"10.1007/s10461-025-04653-7","DOIUrl":"10.1007/s10461-025-04653-7","url":null,"abstract":"<p><p>Type 2 diabetes (T2DM) and depressive symptoms frequently co-occur among people with HIV (PWH). Depression may impact diabetes management in PWH. This study evaluated the prevalence of concurrent T2DM and depression among PWH and the impact of depression and HIV symptoms on glycemic outcomes (hemoglobin A1c [A1c], blood glucose [BG]) among people with both HIV and T2DM. We conducted a secondary analysis in the CFAR Network of Integrated Clinical Systems, a multisite clinical cohort including a diverse population of PWH in care from July 2005 through July 2023. Linear regression and linear mixed models were used to estimate the association between depression, HIV symptoms, and glycemic outcomes (A1C, BG) at baseline and over time. Of the 18,562 PWH, 2,945 (16%) also had T2DM. PWH with T2DM were older (56 vs. 49 years) and more often non-Hispanic Black and cis-gender men. The prevalence of depression was not significantly different between PWH with or without T2DM (20% vs. 21%) although more PWH with T2DM received antidepressant medications. Among people with both HIV and T2DM, HIV baseline symptoms and depression were not associated with a change in A1c. Increases in time-updated HIV symptom scores were associated with random (non-fasting) BG levels, with each additional HIV symptom resulting in 0.8 mg/dL increase in random BG level (95% CI: 0.04-1.60, p = 0.04). The prevalence of T2DM was higher among PWH than in the general population. Although depression appears to be well managed, other factors impacting glycemic outcomes among people with both HIV and T2DM require further study.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Financial Incentives on Intimate Partner Violence for Women Living with HIV Initiating Antiretroviral Therapy 经济激励对开始抗逆转录病毒治疗的感染艾滋病毒的妇女的亲密伴侣暴力的影响。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-17 DOI: 10.1007/s10461-025-04621-1
Rebecca Hémono, Emmanuel Katabaro, Babuu Joseph, Hamza Maila, Janeth Msasa, Kassim Hassan, Solis Winters, Ndola Prata, William H. Dow, Prosper Njau, Amon Sabasaba, Sandra I. McCoy
{"title":"Impact of Financial Incentives on Intimate Partner Violence for Women Living with HIV Initiating Antiretroviral Therapy","authors":"Rebecca Hémono,&nbsp;Emmanuel Katabaro,&nbsp;Babuu Joseph,&nbsp;Hamza Maila,&nbsp;Janeth Msasa,&nbsp;Kassim Hassan,&nbsp;Solis Winters,&nbsp;Ndola Prata,&nbsp;William H. Dow,&nbsp;Prosper Njau,&nbsp;Amon Sabasaba,&nbsp;Sandra I. McCoy","doi":"10.1007/s10461-025-04621-1","DOIUrl":"10.1007/s10461-025-04621-1","url":null,"abstract":"<div><p>Financial incentives have demonstrated effectiveness in improving outcomes for people living with HIV; however, little is known about their impact on intimate partner violence (IPV) in this vulnerable population. A cluster-randomized trial investigating financial incentives and viral suppression was conducted in the Lake Zone of Tanzania (clinicaltrials.gov: NCT0420135). Between May 2021-March 2022, 32 clinics were randomized 1:1 to receive the standard of care (SOC) or to offer 22,500 TZS (~$10 USD) to individuals initiating antiretroviral therapy monthly for up to 6 months, conditional on clinic attendance. An intention-to-treat analysis was conducted to examine the effect of financial incentives on IPV among partnered women at 6 months (<i>n</i> = 494), with prevalence differences (PD) and 95% confidence intervals (CI) estimated using generalized estimating equations. Subgroup analyses were conducted among women partnered at 6 months only and women partnered at both baseline and 6 months. Past 6-month IPV was reported by 241 (48.8%) partnered women. Emotional IPV was the most common form of violence (47.8%), followed by physical (7.5%) and sexual IPV (5.1%). There were no significant differences in past 6-month IPV between arms in the primary (49.6% SOC vs. 48.1% incentive, PD: -0.02, 95% CI: -0.18, 0.15) or subgroup analyses. These findings suggest that small, short-term financial incentives used to improve HIV treatment outcomes do not significantly alter IPV risks, however with the width of the CIs it is not possible to rule out small and moderate-sized effects. Further research among larger samples is needed as financial incentive programs are brought to scale for people living with HIV.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1507 - 1515"},"PeriodicalIF":2.7,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10461-025-04621-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Factors Influencing the Nutritional Status of HIV-Exposed Infants: A 12-Month Follow-Up in Mathare and Kibera Informal Settlements in Nairobi County. 影响艾滋病毒暴露婴儿营养状况的产妇因素:在内罗毕县马萨雷和基贝拉非正式住区进行的12个月随访
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-14 DOI: 10.1007/s10461-025-04648-4
Elizabeth Mueke Kiilu, Simon Karanja, Gideon Kikuvi, Linet Muthoki
{"title":"Maternal Factors Influencing the Nutritional Status of HIV-Exposed Infants: A 12-Month Follow-Up in Mathare and Kibera Informal Settlements in Nairobi County.","authors":"Elizabeth Mueke Kiilu, Simon Karanja, Gideon Kikuvi, Linet Muthoki","doi":"10.1007/s10461-025-04648-4","DOIUrl":"https://doi.org/10.1007/s10461-025-04648-4","url":null,"abstract":"<p><p>Optimal infant nutrition is crucial for good health and survival. HIV-exposed infants have a greater incidence of low birthweight than HIV-unexposed infants, predisposing them to malnutrition and a greater risk of HIV infection. A 12-month longitudinal study was conducted on 166 HIV-exposed infants, assessing nutritional status at 6 weeks, 6 months, and 12 months. Fisher's test and logistic regression analysed the data using WHO growth standards. Ethical approval was obtained (KEMRI/SERU/CPHR/002/3525). Results: Wasting: Younger maternal age (18-24 years) presented higher odds of infant wasting across all timepoints: 6 weeks aOR 4.31 (CI: 1.11, 1.83), 6 months aOR 4.49 (CI: 1.09, 27.34), and 12 months aOR 5.49 (CI: 1.41, 32.97). Stunting: At 6 months, infants of underweight mothers and those on second-line antiretroviral therapy (ART) regimens had higher odds of stunting aOR 4.76 (CI: 1.36, 16.65) and aOR 5.49 (CI: 1.64, 18.38), respectively. At 12 months, poor maternal ART adherence aOR 4.11 (CI: 1.14, 14.82) and mothers on second-line ART regimens aOR 3.68 (CI: 1.09, 12.49) had increased odds of infant stunting. Underweight: At 6 weeks, high maternal viral load aOR 6.33 (CI: 2.31, 17.36) was associated with higher odds underweight infants, whereas employed mothers had lower odds of underweight infants at 6 and 12 months aOR 0.10 (CI: 0.03, 0.32) and aOR 0.22 (CI: 0.09, 0.59) respectively. The results highlight maternal nutrition and ART adherence's influence on infant nutritional status and HIV vertical transmission risk. The study recommended integrating comprehensive nutritional care into HIV policies and enhancing ART counselling to reduce vertical transmission risk and poor infant growth.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tackling the Triple Threat in Kenya: Factors Associated with Protection against HIV Risk, Gender-Based Violence, and Pregnancy among Adolescent Girls and Young Women. 解决肯尼亚的三重威胁:与预防艾滋病毒风险、性别暴力和少女和年轻妇女怀孕相关的因素。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-13 DOI: 10.1007/s10461-025-04643-9
Brendan Maughan-Brown, Boladé Hamed Banougnin, Madison T Little, Lucas Hertzog, Ntombekhaya Matsha-Carpentier, Celestine Mugambi, Hermes Gichane, Lucie Cluver, Elona Toska
{"title":"Tackling the Triple Threat in Kenya: Factors Associated with Protection against HIV Risk, Gender-Based Violence, and Pregnancy among Adolescent Girls and Young Women.","authors":"Brendan Maughan-Brown, Boladé Hamed Banougnin, Madison T Little, Lucas Hertzog, Ntombekhaya Matsha-Carpentier, Celestine Mugambi, Hermes Gichane, Lucie Cluver, Elona Toska","doi":"10.1007/s10461-025-04643-9","DOIUrl":"https://doi.org/10.1007/s10461-025-04643-9","url":null,"abstract":"<p><p>The government of Kenya's Triple Threat strategy recognises the need for urgent intervention to address the high incidence of HIV, gender-based violence (GBV) and pregnancy among adolescent girls and young women (AGYW). We used nationally representative data among AGYW aged 13-24 (n = 1344) from the 2018-19 Kenya Violence Against Children & Youth Survey (VACS) in multivariable logistic regression analyses to examine associations between three potential protective factors - gender-equitable attitudes, food security and parental monitoring - and outcomes related to the triple threat: Intimate partner violence (IPV); sexual violence; high HIV exposure risk; adolescent pregnancy; child marriage; and not being in school or paid work. Results showed that AGYW with gender-equitable attitudes were less likely to report IPV (adjusted odds-ratio (aOR):0.47, p < 0.01) and adolescent pregnancy (aOR:0.58, p < 0.05). AGYW who were food secure were less likely to report adolescent pregnancy (aOR:0.57, p < 0.05) and child marriage (aOR:0.51, p < 0.05). Those with high parental monitoring were less likely to report IPV (aOR:0.44, p < 0.01), sexual violence (aOR:0.49, p < 0.05), adolescent pregnancy (aOR:0.61, p < 0.05), and child marriage (aOR:0.41, p < 0.01). AGYW who had gender-equitable attitudes, food security and high parental monitoring (i.e., all three factors compared to none) had lower predicted probabilities of reporting IPV (22.3% vs. 5.0%), sexual violence (20.4% vs. 6.0%), adolescent pregnancy (23.7% vs. 7.7%), and child marriage (10.0% vs. 1.6%). The findings indicate that improving gender-equitable attitudes, food security and parental monitoring may positively impact multiple outcomes related to the triple threat; and that addressing all three may have the greatest impact.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PrEP Awareness and Coverage: Results from the 2022 South Africa Antenatal HIV Sentinel Survey PrEP意识和覆盖率:2022年南非产前艾滋病毒哨点调查结果。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-02-13 DOI: 10.1007/s10461-024-04609-3
Nosipho Shangase, Tendesayi Kufa, Mireille Cheyip, Adrian Puren
{"title":"PrEP Awareness and Coverage: Results from the 2022 South Africa Antenatal HIV Sentinel Survey","authors":"Nosipho Shangase,&nbsp;Tendesayi Kufa,&nbsp;Mireille Cheyip,&nbsp;Adrian Puren","doi":"10.1007/s10461-024-04609-3","DOIUrl":"10.1007/s10461-024-04609-3","url":null,"abstract":"<div><p>Pregnant women have a high HIV incidence in South Africa (SA), increasing the risk of mother-to-child transmission (MTCT) of HIV. Strengthening coverage of HIV prevention strategies such as pre-exposure prophylaxis (PrEP) is essential to ending the epidemic in SA. We estimated awareness and coverage of PrEP among pregnant women attending antenatal clinics. Using the national cross-sectional antenatal HIV sentinel survey SA, that was conducted from February to April 2022, we performed descriptive and survey logistic regression analyses. Women were deemed as aware about PrEP if they reported ever having heard of PrEP. Women were eligible for PrEP if they were HIV-negative and had either: (1) an HIV-positive/status-unknown partner; (2) multiple sexual partners in the past twelve months; (3) a sexually transmitted infection in the preceding six months; or (4) sex under the influence of alcohol/drugs in the past six months. 31.18% (<i>n</i> = 7 271) of HIV-negative women were eligible for PrEP. Among eligible women, 33.65% (<i>n</i> = 2 403) were aware about PrEP, 3.58% (<i>n</i> = 271) took PrEP before pregnancy, and 6.50% (<i>n</i> = 507) were currently on PrEP. Compared to follow-up visit attendees, first ANC visit attendees were less likely to be: (1) aware about PrEP (adjusted odds ratio (aOR) = 0.65; 95% confidence interval (CI): 0.59–0.72), and (2) to currently be on PrEP (aOR = 0.69; 95% CI: 0.57–0.84). Women who had never tested for HIV before pregnancy were less likely to: (1) be aware about PrEP (aOR = 0.51; 95% CI: 0.45–0.59), and (2) currently be on PrEP (aOR = 0.56; 95% CI: 0.43–0.74) compared to those who had tested for HIV before pregnancy. Women who reported having an HIV-positive partner compared to those with an HIV-negative partner had higher: (1) PrEP awareness (aOR = 2.21; 95% CI: 1.80–2.71), and (2) PrEP coverage during pregnancy (aOR = 8.51; 95% CI: 6.43–11.25). Overall PrEP awareness and coverage were low. PrEP is being integrated into safe conception programs as an HIV prevention strategy. Entry into ANC presents an important opportunity to prevent new HIV infections among new mothers, accelerating the elimination of MTCT of HIV in the country.</p></div>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":"29 5","pages":"1692 - 1703"},"PeriodicalIF":2.7,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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