AIDS and Behavior最新文献

{"title":"Undermining America's HIV Prevention Capacity: Wrong and Dangerous.","authors":"Ronald O Valdiserri","doi":"10.1007/s10461-025-04770-3","DOIUrl":"10.1007/s10461-025-04770-3","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":"2037-2038"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventions and Strategies to Increase Cervical Cancer Screening, Treatment, and Retention in Care among Persons with HIV in Low- and Middle-Income Countries: A Systematic Review.","authors":"Riya Mittal, Katherine E Kabel, Madison R Fertig, Jane H Lee, Nzwakie Mosery, Jennifer N Githaiga, Jenni Smit, Christina Psaros, Amelia M Stanton","doi":"10.1007/s10461-025-04678-y","DOIUrl":"10.1007/s10461-025-04678-y","url":null,"abstract":"<p><p>Cervical cancer (CC) and HIV pose two major public health challenges, with low and middle-income countries (LMICs) exhibiting the highest disease burden and mortality rate for both HIV and CC-related deaths worldwide. Populations with HIV in LMICs are six times more likely to develop CC compared to the general population. Further, CC is the most frequently detected cancer and leading cause of death among women with HIV (WWH). This systematic review synthesized the literature and identified key elements of interventions to increase CC awareness, screening, treatment, and retention in care among persons with HIV in LMICs. Four databases were searched for peer reviewed articles in the last 10 years that described and assessed the effectiveness of these interventions, and 10 articles were identified and reviewed. Interventions that included community/spiritual leaders, trained non-physician medical providers, used pre-existing facilities (e.g. HIV, family planning, reproductive health), integrated \"screen and treat\" approaches, and used visual inspection methods (VIA/VILI; excluding Pap smears) were associated with higher rates of CC awareness, screening, engagement in subsequent treatment, and overall retention in care. Most studies focused on increasing awareness, screening, and engagement in care, demonstrating the need for interventions that are also designed to increase retention in the CC continuum of care among WWH. Additionally, few interventions had long follow-up periods, which should be included to effectively track sustained retention in care.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":"2144-2157"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12229762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of DEI on HIV Research.","authors":"David M Stoff","doi":"10.1007/s10461-025-04715-w","DOIUrl":"10.1007/s10461-025-04715-w","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":"2039-2042"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rapid Review of HIV-Related Stigma-Reduction Randomized Controlled Trials.","authors":"Paul C J Berthe, Yanis Ben Amor","doi":"10.1007/s10461-025-04673-3","DOIUrl":"10.1007/s10461-025-04673-3","url":null,"abstract":"<p><p>We conducted a rapid review to identify and describe randomized controlled trials (RCTs) aimed at reducing HIV-related stigma. Using a rapid review design in accordance with PRISMA guidelines, we searched five major databases (PubMed, PsycINFO, OVID/Medline, EMBASE, and Scopus) from July 1981 to June 2023, and analyzed 27 studies from an initial pool of 2,383 articles. Our analysis revealed three primary intervention strategies: (1) alleviating internalized stigma through confidence-building and emotional validation, (2) addressing anticipated and enacted stigma via training and sensitization campaigns, and (3) challenging institutional and cultural beliefs through macro-scale interventions. Community-driven approaches and locally-engaged interventions demonstrated particular promise, especially in resource-constrained settings. While intrapersonal and interpersonal approaches-particularly those involving professional discussions, peer education, and in-person training-showed the most positive outcomes, digital and infotainment interventions yielded mixed results. Our findings highlight the complexity of HIV-related stigma, revealing the importance of holistic strategies that address intersecting psychosocial factors and potential unintended consequences of stigma-reduction efforts. By studying the nuanced landscape of stigma intervention, this review provides insights for developing more comprehensive and contextually sensitive approaches to reducing HIV-related stigma.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":"2088-2106"},"PeriodicalIF":2.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143787680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination HIV Prevention Strategies in the Lisbon Cohort of Men who Have Sex with Men: A Longitudinal Cluster Analysis of Data from 2014 to 2021.","authors":"Rita Dias, Miguel Rocha, Luís Veríssimo, Fernando Ferreira, Maria João Novais, Milton Severo, Sílvia Fraga, Paula Meireles","doi":"10.1007/s10461-025-04693-z","DOIUrl":"10.1007/s10461-025-04693-z","url":null,"abstract":"<p><p>This study aims to examine how HIV prevention tools were used and how they clustered together among men who have sex with men (MSM) testing at a community-based sexual health center in Lisbon, Portugal, from 2014 to 2021. We used data from 16,780 visits from adult cisgender MSM and had an HIV-negative test result at baseline in the Lisbon Cohort of MSM-an open, prospective cohort study conducted at CheckpointLX, a community-based sexual health center tailored to MSM, from 2014 to 2021. A longitudinal clustering approach was used to identify clusters of HIV prevention (cluster package for R). Six clusters of HIV prevention were identified: condom use (9,109 visits); low or no condom use, low PrEP (preexposure prophylaxis) use (6,258 visits); anal sex abstinence (746 visits); PEP (postexposure prophylaxis) and condom use (305 visits); PEP use (186 visits); and PrEP and condom use (176 visits). Most participants were aged 24 to 34 years old, were born in Portugal, had high education, and self-identified as gay. PrEP and PEP uptake were more associated with being born in Brazil, while low prevention adherence was less associated with high education. Condom use was the most frequently reported prevention strategy, followed by the low or no condom use, low PrEP use cluster. However, participants with higher odds of reporting HIV risk behaviors were the ones allocated to clusters with reports of higher frequency of prevention tools utilization.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":"2299-2311"},"PeriodicalIF":2.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and Reliability of the Kessler 6 Scale for Serious Mental Illness Among Populations with High Burden of HIV.","authors":"Rashunda Lewis, Monica Adams, Evelyn Olansky, Catlainn Sionean","doi":"10.1007/s10461-025-04765-0","DOIUrl":"https://doi.org/10.1007/s10461-025-04765-0","url":null,"abstract":"<p><p>The Kessler 6 (K6) scale has been widely used to screen for serious mental illness (SMI) in general populations. Given that populations with high burden of HIV may be more likely to experience poor mental health outcomes, it is important to validate measures used to assess SMI among these groups. Using data from CDC's National HIV Behavioral Surveillance (NHBS) system in the United States, we examined psychometric characteristics of the K6 scale, including exploratory factor analysis, scale reliability, construct validity, and review of interviewer feedback to explore scale performance in the field. Analyses confirmed a single factor structure and demonstrated that the K6 scale had high internal consistency and construct validity. Although interviewers noted that the effort item was difficult for some participants to understand, psychometric properties were not greatly improved with the deletion of the item. The results of this analysis suggest that the K6 scale is appropriate for use among NHBS populations with a high burden of HIV, including persons who inject drugs, heterosexually active adults at increased risk for HIV infection, women who exchange sex for money or drugs, and gay, bisexual, and other men who have sex with men.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Intersectional Stigma and Psychological Well-Being Among Men Who Have Sex with Men Living with HIV.","authors":"Tianyue Mi, Xueying Yang, Guanghua Lan, Shan Qiao, Zhiyong Shen, Yuejiao Zhou, Xiaoming Li","doi":"10.1007/s10461-025-04795-8","DOIUrl":"https://doi.org/10.1007/s10461-025-04795-8","url":null,"abstract":"<p><p>Men who have sex with men (MSM) living with HIV face considerable psychosocial challenges, including stigma and discrimination, which may affect their mental health. Instead of considering each stigmatized identity in isolation, this study investigated the association between intersected HIV- and MSM-related stigma and psychological well-being of MSM living with HIV. Data of 402 MSM living with HIV were collected through a cross-sectional study in Guangxi, China, focusing on the association between HIV-/MSM-related stigma and HIV-related health outcomes among MSM living with HIV. Latent Moderated Structural Equations Approach was employed to examine the moderation effect of MSM-related stigma on the relationship between HIV-related stigma and mental health outcomes. The findings revealed that with a lower level of MSM-related stigma, the associations between HIV-related stigma and depression (β = 0.99, 95%CI [-0.63, 2.61], p = 0.23) or anxiety (β = 1.61, 95%CI [-0.44, 3.65], p = 0.12) were not significant; with a higher level of MSM-related stigma, the association between HIV-related stigma and depression (β = 3.32, 95%CI [1.67, 4.96], p < 0.001) or anxiety (β = 4.95, 95%CI [2.68, 7.22], p < 0.001) showed significant positive associations. The study demonstrates that higher levels of MSM-related stigma can intensify the relationship between HIV-related stigma and depression/anxiety among MSM. By emphasizing the role of intersectional stigma in adverse mental health outcomes, these findings will inform the development of effective and sustainable health strategies, policies, and services, including tailored mental health services and community-led stigma reduction programs aimed at the enhancement of well-being among MSM living with HIV.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Interplay of Social and Physical Factors in Risk Dynamics and Transitions Across the Life-Course of Female Sex Workers in Blantyre, Malawi: A Longitudinal Narrative Study.","authors":"Wezzie Stephanie Lora, Doreen Sakala, Amr Saidi, Wezzie Nyapigoti, Esnart Sanudi, Maryam Shahmanesh, Frances M Cowan, Joanna Busza, Nicola Desmond","doi":"10.1007/s10461-025-04790-z","DOIUrl":"https://doi.org/10.1007/s10461-025-04790-z","url":null,"abstract":"<p><p>Sexual risk amongst female sex workers (FSW) varies across the life-course and is influenced by socio-economic and interpersonal factors that affect behavioural choices and engagement in HIV/STI care. We explored transitions in the life-course of FSW to understand the dynamics of sexual risk in Blantyre, Malawi. We implemented a nested longitudinal qualitative study as part of the AMETHIST Consortium, a study testing approaches to reduce HIV transmission in sex work. We conducted consecutive narrative interviews with 30 FSW at three-time points over 12 months, with a three- to four-month break between each time point. We compared narratives to understand sex work transitions, HIV risk and engagement with HIV services. We identified factors (social and physical) related to sexual risk at the points of (1) transitions into sex work, (2) continuing sex work, and (3) breaks in sex work. At the entry stage, sexual risk was heightened when women lacked the knowledge and skills for protection against HIV/STI. Whilst continuing sex work, women's immediate financial needs were prioritised over their HIV/STI risk. These behaviours occurred whether they were aware of the associated HIV/STI risk. During breaks, women perceived lower risk and reduced engagement in prevention strategies, particularly when they had stable partners, which paradoxically increased their risk. These narratives reveal how social context informs and limits access to health care while concurrently promoting risky behaviours. A multifaceted and dynamically responsive approach that considers risk differentiation from a temporal perspective can strengthen targeted interventions, effectively addressing the multiple challenges faced by FSW.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated with Use of Protective Barriers Against HIV and Other Sexually Transmitted Infections During Sexual Behavior in Transmasculine and Nonbinary Adults from Argentina.","authors":"Pablo D Radusky, Romina Caballero, Virginia Zalazar, Nadir Cardozo, Boris Brunori, Marcela Romero, Caro Mattie Dumas Pelletti, Ines Aristegui","doi":"10.1007/s10461-025-04762-3","DOIUrl":"https://doi.org/10.1007/s10461-025-04762-3","url":null,"abstract":"<p><p>Evidence suggests a substantial burden of sexually transmitted infections (STIs) and high proportions of sexual behavior with no protective barriers in transmasculine and nonbinary individuals. However, research on this population's sexual health has been scarce, especially in the Latin American region. This study sought to determine the prevalence of self-reported STIs, and to explore correlates of use of protective barriers during sexual behavior among transmasculine and nonbinary individuals in Argentina. A sample of 304 participants responded to a questionnaire online to explore sociodemographic variables, history of HIV and other STIs, access to sexual and gender-affirming healthcare, and sexual behavior. Chi-square tests were calculated, and bivariate and multivariable logistic regression analyses were conducted to identify correlates of use of protective barriers during sexual behavior. Almost a quarter (23.4%) self-reported lifetime diagnosis of at least one STI and 63.8% did not use any protective barriers in their last sexual relation. Use of protective barriers during sexual behavior was negatively associated with insertive frontal/genital sexual behavior and with sex with cisgender women in the last month, and positively associated with ever attending a gynecologic examination, sex with cisgender men in the last month and lifetime transactional sex. Only these last two variables remained associated with use of protective barriers in the multivariable model. Use of protective barriers differs by type of sexual behavior and partner in transmasculine and nonbinary people. Sexual healthcare targeting this community should take this into consideration, and preventive interventions should be tailored to each individual's self-reported sexual behaviors.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intimate Partner Violence Perpetration and PrEP Use Among Sexual Minority Men: The Mediating Roles of Internalized Homonegativity and PrEP Stigma.","authors":"Erik D Storholm, Jessica Randazzo, Chenglin Hong, Daniel E Siconolfi, Carrie L Nacht, Sarita D Lee, Glenn J Wagner","doi":"10.1007/s10461-025-04802-y","DOIUrl":"https://doi.org/10.1007/s10461-025-04802-y","url":null,"abstract":"<p><p>Cisgender sexual minority men (SMM) report intimate partner violence (IPV) at rates comparable to or higher than heterosexual cisgender women, often linked to increased HIV risk. This study explores the relationship between IPV perpetration and pre-exposure prophylaxis (PrEP), considering the potential mediating effects of sexual orientation related minority stress and PrEP stigma. Utilizing baseline data from the Empowering Relationships and Opportunities for Safety (EROS) cohort, this cross-sectional study examined survey data from partnered cisgender SMM in the U.S. Through online and community recruitment, participants were assessed for IPV perpetration using a validated measure, while internalized homonegativity and related stigma were evaluated through standardized scales. Current PrEP use was assessed through self-report and confirmed through dried blood spot assays. Of the 500 participants, 125 (25%) reported IPV perpetration, with perpetration of identity-related IPV (e.g., threatening to out a partner to family or coworkers; telling partner to act straight) significantly higher among non-PrEP users; mean number of identity-related IPV perpetration items endorsed was 0.21 (SD = 0.53) among non-PrEP users compared to 0.02 (SD = 0.14) among PrEP users. Perpetration of identity-related IPV was positively correlated with internalized homonegativity (r =.19, p <.001), experienced sexual orientation discrimination (r =.15, p <.01), and PrEP stigma (r =.14, p <.001). A logistic regression mediation analysis found that, separately, internalized homonegativity (OR = 0.97, 95% CI [0.94-0.99]) and PrEP stigma (OR = 0.48, 95% CI [0.40, 0.57]) had significant associations with PrEP use, and that each mediated the relationship between perpetration of identity-related IPV and PrEP use as demonstrated by their significant indirect effects (OR = 0.88, 95% CI [0.78, 0.98] and (OR = 0.77, 95% CI [0.60, 0.98], respectively). The study underscores internalized homonegativity and PrEP stigma as critical mediators of the relationship between perpetration of identity-related IPV and PrEP use among SMM. Findings call for interventions aimed at reducing internalized homonegativity, PrEP stigma and enhancing PrEP access while addressing IPV dynamics. Future research should further delineate these pathways to inform culturally sensitive interventions promoting health equity among SMM.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}