AIDS and Behavior最新文献

{"title":"Better Together?: A Systematic Review of the Effectiveness of HIV Prevention Interventions that Build or Strengthen Social Ties.","authors":"Virginia A Fonner, Ping Teresa Yeh, Caitlin E Kennedy, Kevin R O'Reilly, Michael D Sweat","doi":"10.1007/s10461-025-04745-4","DOIUrl":"https://doi.org/10.1007/s10461-025-04745-4","url":null,"abstract":"<p><p>Although social relationships impact health and social dynamics play a key role in shaping HIV vulnerability, results from intentional efforts to build or strengthen social relationships have not been synthesized to understand if and how such interventions work to prevent HIV in low- and middle-income countries (LMICs). We conducted a systematic review of HIV prevention interventions implemented in LMICs, published between 2010 and 2022, that used pre/post or multi-arm methods to evaluate interventions that focused on building/strengthening social relationships to impact HIV-related outcomes. We searched PubMed, CINAHL, EMBASE, Sociological Abstracts, and PsycInfo on August 16, 2022, complemented by hand-searching and secondary reference searching. We used a standardized form for data abstraction and assessed risk of bias using the Evidence Project tool. Results were synthesized narratively, and studies were classified in an emergent typology based on the function of social tie building within the intervention. Fifty-one articles presenting results from 28 studies met the inclusion criteria and were included. Within these studies, we identified five types of social tie interventions, including community-wide social mobilization (\"collaboration\", n = 3), formation of collectives to address both upstream and downstream health-related factors (\"collectivization\", n = 13), forming or strengthening groups to enhance peer support and build skills (\"clubs\", n = 4), expanding personal networks among individuals (\"companionship\", n = 2), and strengthening ties between heterogeneous groups/non-peers (\"connections\", n = 2). Four studies addressed two or more types of social ties strengthening and were classified as \"cross-cutting.\" Across these categories, most studies found that interventions were associated with some positive health-related changes, such as reduced HIV incidence, increased condom use, and increased health service utilization. However, some interventions fell short of their stated goals, especially those striving to impact upstream social and structural factors. Overall, results suggest that social ties can be intentionally altered to effect change; however, disparate contexts and implementation dynamics likely contributed to variation seen across outcomes and impact. Inconsistent measurement of social ties and use of theory made it challenging to determine whether interventions were explicitly trying to alter ties, and if so, to what extent tie building/strengthening impacted intervention effectiveness. To continue advancing our understanding of social tie interventions, more efforts are needed to operationalize theory, measure social tie constructs, describe intervention context and implementation outcomes, and apply innovative study designs.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Modeling the Mediating Effects of HIV-Related Stigma on the Associations Between Race/Ethnicity and Antiretroviral Therapy Adherence and Viral Suppression Among Diverse Racial and Ethnic Minority Women with HIV.","authors":"Ekpereka S Nawfal, Diana M Sheehan, Gladys E Ibañez, Timothy Hayes, Aaliyah Gray, Mary Jo Trepka","doi":"10.1007/s10461-025-04758-z","DOIUrl":"https://doi.org/10.1007/s10461-025-04758-z","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of a Family Economic Empowerment Intervention on Cultural Gender Norm Beliefs Among HIV-Orphaned Adolescents in Southern Uganda.","authors":"Portia B Nartey, Vicent Ssentumbwe, Proscovia Nabunya, Samuel Kizito, Mitra Naseh, Fred M Ssewamala","doi":"10.1007/s10461-025-04750-7","DOIUrl":"https://doi.org/10.1007/s10461-025-04750-7","url":null,"abstract":"<p><p>Sub-Saharan Africa (SSA) ranks lowest on the UNDP's Gender Inequality Index (GII), with a score of 0.56 out of 1 (1 being the worst), while Uganda scores 0.53, reflecting high gender inequality between males and females. These gender disparities are deeply rooted in longstanding inequitable gender norms and worsened by poverty. This study assessed a family economic empowerment intervention's impact on gender norm beliefs among HIV-orphaned adolescents in Uganda using three time-points data from the Suubi-Maka study, a cluster-randomized trial with 346 adolescent-caregiver dyads. Participants were randomized to control (n = 167) or treatment (n = 179) groups, with data collected at baseline, 12, and 24 months. We used mixed effects linear regression to assess the effect of the economic empowerment intervention on gender norms. Results indicated significant group-by-time interaction effects but non-significant independent group or time effects. Social support was positively significantly associated with equitable gender norms, emphasizing the role of supportive networks in facilitating change in gender norm beliefs. These findings suggest that economic interventions alone may not be sufficient for altering deeply entrenched gender norms, and future efforts should include more targeted, gender-transformative approaches.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily Factors Associated with Antiretroviral Therapy Adherence Among Young Latino Sexual Minority Men with HIV: A 28-Day Daily Diary Study.","authors":"Diana M Sheehan, Daisy Ramírez-Ortiz, Tendai Gwanzura, Patrice S Lewis, Melissa M Ertl, Dustin T Duncan, Dallas Swendeman, Miguel Muñoz-Laboy, Jessy G Devieux, Mary Jo Trepka","doi":"10.1007/s10461-025-04756-1","DOIUrl":"https://doi.org/10.1007/s10461-025-04756-1","url":null,"abstract":"<p><p>We assessed the relationship between same-day and next-day antiretroviral therapy (ART) adherence and adherence self-efficacy, daily routine disruptions, mental health, sleep, social support, substance use, and contextual factors in an ecological momentary assessment (EMA) study. Twenty-eight days of data from a convenience sample of 54 18-34-year-old young Latino sexual minority men (YLSMM) was used in generalized mixed models. Participants adhered to ARTs on 96% of 1,306 person-days. Daily motivation to stay healthy, to prevent HIV transmission, and ART self-efficacy were associated with same-day adherence. Routine disruptions, poor sleep, and drug use were associated with same-day non-adherence. Stress was associated with next-day non-adherence, and increased routine disruptions with non-adherence. Findings suggest an opportunity to design and test innovative interventions for YLSMM to improve ART adherence that increase daily adherence motivation and self-efficacy and provide real-time assistance during changes in routine, poor sleep, drug use, and stress.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Health-Related Quality of Life in People Living with HIV Who Present to Care with AIDS or Severe Immunodeficiency: The CoRIS AIDS Survivors Study.","authors":"Julia Portilla-Tamarit, María José Fuster-RuizdeApodaca, Irene Portilla-Tamarit, Sergio Reus, Melchor Riera, Nuria Espinosa, Juan Martín, Enrique Bernal, Mar Masia, Sonia Calzado, Joaquín Portilla","doi":"10.1007/s10461-025-04730-x","DOIUrl":"https://doi.org/10.1007/s10461-025-04730-x","url":null,"abstract":"<p><p>Our aim was to evaluate long-term health-related quality of life (HRQoL) in 253 people living with HIV (PLH) from the CoRIS cohort presenting to care with advanced HIV disease (AIDS or CD4 ≤ 100 cells/µL) and who had survived ≥ 5 years. Participants completed the WHOQOL-HIV-BREF and EQ-5D-5 L questionnaires. Clinical and immunological data were provided by the CoRIS at enrollment and on questionnaire completion. Linear repeated measures analyses assessed the evolution of immunological markers. Partial least squares structural equation modeling showed the longitudinal impact of baseline immunological markers on HRQoL. High baseline CD4 counts predicted higher WHOQOL-HIV-BREF independence scores (p = 0.021) and a marginally higher EQ-5D-5 L index value (p = 0.058), which was also associated with CD8 (p = 0.015). A higher CD4/CD8 ratio predicted lower scores on the WHOQOL-HIV-BREF 'spirituality, religion and personal belief' dimension (p = 0.006). Currently, PLH who present with advanced HIV disease achieve a moderate long-term HRQoL, with room for improvement.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability and Feasibility of Remote PrEP Visits for Adolescent Girls and Young Women in South Africa.","authors":"Makhosazane Nomhle Ndimande-Khoza, Jennifer Velloza, Hlukelo Chauke, Lisa Mills, Nicole Poovan, Nontokozo Ndlovu, Tessa Concepcion, Sybil Hosek, Connie Celum, Sinead Delany-Moretlwe","doi":"10.1007/s10461-025-04705-y","DOIUrl":"https://doi.org/10.1007/s10461-025-04705-y","url":null,"abstract":"<p><p>The World Health Organization recommends differentiated service delivery (DSD) models for HIV prevention, including alternatives to clinic-based PrEP services. This study assessed the acceptability and feasibility of remote PrEP delivery-including HIV and pregnancy self-testing, and phone-based adherence counselling-among adolescent girls and young women (AGYW) in Johannesburg. The research was nested within the PrEP SMART trial (2019-2022), which evaluated scalable adherence support strategies for AGYW aged 18-25. During COVID-19 lockdowns, PrEP refills and testing kits were delivered to participants' homes, and counselling was provided by phone. Using a phenomenological qualitative method, we conducted in-depth interviews with AGYW (n = 14) who had the option to complete remote PrEP visits (accepting or declining), study staff (n = 12), and key informants (n = 10) involved in PrEP programming. Thematic analysis explored experiences of remote delivery, focusing on acceptability and feasibility. AGYW found remote PrEP visits convenient, empowering, and time-saving. Procedures such as self-testing and phone counselling were generally acceptable, though some expressed anxiety about performing tests incorrectly and concerns over privacy, stigma, and unintentional disclosure of PrEP use at home. About half still preferred clinic-based visits. Staff and key informants recognized benefits, but highlighted challenges related to cost, sustainability, and provider workload. Suggestions for improvement included integrating contraception and partnering with community organizations. In conclusion, remote PrEP delivery is acceptable and feasible for many AGYW but not universally suitable. These findings support the inclusion of remote PrEP options in DSD models, with attention to privacy concerns and support for self-testing in this age group.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative Results from a Pilot Study of an Automated Directly Observed Therapy Intervention Using Artificial Intelligence with Conditional Economic Incentives among Young Adults with HIV.","authors":"L Danielle Wagner, Noah Mancuso, Marie C D Stoner, Louis Smith, Kristin Ming, Henna Patani, Adam C Sukhija-Cohen, Yancy Granados, Sue Napierala, Parya Saberi","doi":"10.1007/s10461-025-04748-1","DOIUrl":"https://doi.org/10.1007/s10461-025-04748-1","url":null,"abstract":"<p><p>Digitally monitoring and supporting daily antiretroviral therapy (ART) is a promising strategy for enhanced adherence among young adults with HIV (YWH). We implemented an innovative mobile app-based intervention that included automated directly observed therapy (aDOT) using artificial intelligence, medication reminders, and conditional economic incentives (CEIs). This intervention used facial recognition to track and record YWH's daily ART adherence. CEIs were given based on daily app use. A pilot study of the aDOT + CEI app intervention was conducted among YWH ages 18-29 for 3 months. We recruited virally unsuppressed YWH from AIDS Healthcare Foundation clinics in California and Florida and conducted qualitative interviews with YWH and providers regarding the intervention's motivators, deterrents, and helpfulness. Thirteen YWH and 5 providers were interviewed. YWH found the CEIs supported their adherence; however, most YWH did not find the CEI amount sufficiently motivating. The primary motivator for consistent app use was to improve health, and the app reminders were most helpful in improving adherence. YWH desired more reassurance and explanation about app privacy features. Providers suggested incorporating the intervention into counseling for newly diagnosed patients and recommended the intervention to help facilitate viral suppression with oral ART for those interested in transitioning to long-acting injectable ART. YWH and providers found the intervention helpful in reminders to take ART and in tracking adherence. Refinements to the CEI amount may further enhance the intervention. Additional research is needed to test the efficacy of a refined aDOT + CEI intervention to improve viral suppression in a larger sample.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of Adherence Measures for Oral, Tenofovir-Based HIV Pre-Exposure Prophylaxis: A Systematic Review.","authors":"Diana Zeballos, Nathalia Sernizon Guimarães, Marcos Pereira, Laio Magno, Inês Dourado","doi":"10.1007/s10461-025-04741-8","DOIUrl":"https://doi.org/10.1007/s10461-025-04741-8","url":null,"abstract":"<p><p>Accurate adherence measures to HIV pre-exposure prophylaxis (PrEP) are essential for identifying individuals with low adherence and providing tailored support. This systematic review summarizes evidence on the performance of PrEP indirect adherence measures and explores their potential use in clinical practice. Following a registered protocol (PROSPERO: CRD42020144733) we searched PubMed, Embase, LILACS and Web of Science until December 2024. We included studies that assessed PrEP adherence among individuals using daily oral PrEP with tenofovir disoproxil fumarate plus emtricitabine (TDF/FTC). The reference standard involved quantifying PrEP in dried blood spots or plasma, and index tests included self-reported adherence, pill counts, pharmacy records, electronic monitoring, or composite measures. We used QUADAS-2 to assess the risk of bias and applicability concerns. Twenty-three studies, which included 6649 individuals, fulfilled the inclusion criteria. Most were observational studies (n = 17, 73.9%), and the most common measure was self-report (n = 18, 78.3%). The performance of indirect measures was reported through accuracy statistics in 12 studies (52.2%), concordance in two (8.7%), correlation in eight (34.8%), and proportions in one (4.3%). The risk of bias and applicability concerns were generally low or unclear due to unclear reporting. This review underscores the wide heterogeneity of indirect measures used to assess PrEP adherence, with self-reports being the most frequently utilized. Despite some correlation with direct measures, these methods showed mixed evidence of accuracy, with studies reporting moderate discriminatory capacity for identifying high protective levels of TFV-DP. This finding limits the broader applicability of the measures and underscores the need for further research.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metrics of Mobility by Sex are Associated with HIV Incidence in Rural Kenya and Uganda.","authors":"Carol S Camlin, Sarah A Gutin, Edwin D Charlebois, Torsten B Neilands, Laura B Balzer, Maya L Petersen, Gabriel Chamie, Craig R Cohen, Elizabeth A Bukusi, Moses R Kamya, Diane V Havlir, James Ayieko","doi":"10.1007/s10461-025-04743-6","DOIUrl":"https://doi.org/10.1007/s10461-025-04743-6","url":null,"abstract":"<p><p>The complex and dynamic nature of human mobility requires use of multiple measures and sex-stratified analyses to fully understand its influence on HIV acquisition risk in specific populations and settings. Longitudinal population-based studies designed to measure the influence of mobility (which includes both short and long-term, temporary and permanent changes of residence across defined geopolitical boundaries) on HIV acquisition risk are rare, but needed to understand the ongoing challenges that mobility poses to progress in ending HIV. Incidence of HIV acquisition over 3 years was measured in mobile and non-mobile adults in 32 rural communities in three regions of Uganda and Kenya participating in the Sustainable East Africa Research in Community Health (SEARCH) trial (NCT01864603) from 2013-2017. Poisson regression models were used to estimate incidence rate ratios (IRRs) for HIV acquisition among categories of mobile relative to non-mobile adults, with sex-stratified multivariable models adjusted for community clustering using robust estimators. At baseline, 11,337 adult residents (9.7%) reported living at least 1 month outside their community in the past 12 months (8% women, 11.8% men, p < 0.001). By year three, 8502 HIV incidence cohort members (7.3%) had out-migrated (7.7% women, 7.1% men, p = 0.046), and 5747 adults remaining in the cohort (4.9%) reported living at least 1 month outside of their community in past 12 months (4.1% women, 5.9% men, p < 0.001). Over 3 years, the risk of HIV acquisition was 1.9 times higher in those living ≥ 1 month outside their community in the past 12 months compared to those who had not (Adj IRR = 1.88, 95% CI 1.48-2.38). HIV acquisition risk was 42% higher among men who spent some nights away in the past month at baseline (Adj IRR = 1.42, 95% CI 1.11-1.81), but not for women (Adj IRR = 1.06, 95% CI 0.85-1.32). Mobility was significantly associated with a risk of HIV acquisition among adults in rural communities in Kenya and Uganda in 2013-2017. The effect of mobility on HIV incidence varied by both sex and pattern (frequency, duration) of mobility (SEARCH ClinicalTrials.gov number, NCT01864603).</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intimate Partner Violence and Determinants of HIV Seroconversion among Female Caregivers in Kwazulu-Natal, South Africa: Insights from the Asenze Longitudinal Study.","authors":"Christopher M Ferraris, Rachel S Gruver, Gavin George, Leslie L Davidson, Chris Desmond, Anthony F Santoro, Sahba Besharati, Justin Knox","doi":"10.1007/s10461-025-04697-9","DOIUrl":"https://doi.org/10.1007/s10461-025-04697-9","url":null,"abstract":"<p><p>Intimate partner violence (IPV) has been associated with HIV seroconversion vulnerability, but few studies have examined multiple IPV types and HIV status. This study investigates exposure to various IPV types and HIV seroconversion among female caregivers in KwaZulu-Natal (KZN), South Africa, using longitudinal data (2008-2021) from the Asenze cohort study. We compared IPV exposure at baseline (Wave 1[W1]), sociodemographic, and psychosocial characteristics between women living with HIV (WLHIV) vs. HIV-negative at baseline; HIV-negative at baseline who seroconverted by Wave 3 (W3) vs. remaining HIV-negative, using chi-squared and t-tests. We also assessed seroconversion over time in the cohort. At W1, of 580 participants (WLHIV = 139, HIV-negative = 431), 42% reported any IPV. Considering both current and other partners, WLHIV reported higher exposure to threatening IPV (34% vs. 23%, p = .005) and multiple IPV types (32% vs. 23%, p = .029). From an other partner, WLHIV reported more physical IPV (32% vs. 21%, p = .010), any IPV (35% vs. 26%, p = .049), and multiple IPV types (23% vs. 15%, p = .029). No significant differences in IPV from a current partner were found between WLHIV and HIV-negative women. Those who seroconverted by W3 vs. remained HIV-negative at W3 did not differ on any IPV exposures. Women who seroconverted were younger (28.2 vs. 37.8, p <.001) and more likely to report hazardous drinking at W1 (13% vs. 3%, p <.001). The high levels of HIV seroconversion and IPV indicate a persistent HIV and IPV epidemic among female caregivers in KZN, necessitating expanded research and interventions.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}