AIDS and Behavior最新文献

{"title":"Randomized Pilot Trial of the Text-Based Adherence Game for Ghanaian Youth with HIV.","authors":"Nicholas Tarantino, Betty Norman, Anthony Enimil, Shadrack Osei Asibey, Charles Martyn-Dickens, Kathleen O'Neill, Kate M Guthrie, Awewura Kwara, Beth Bock, Matthew J Mimiaga, Larry K Brown","doi":"10.1007/s10461-024-04560-3","DOIUrl":"https://doi.org/10.1007/s10461-024-04560-3","url":null,"abstract":"<p><p>This study examined the feasibility, acceptability, and preliminary efficacy of a mobile intervention called the Text-Based Adherence Game (TAG). TAG aimed to improve HIV treatment adherence among young people with HIV (YPWH) in Ghana. Participants, YPWH aged 18 to 24, were recruited from an HIV clinic in Kumasi, Ghana where study procedures were conducted. A randomized controlled pilot trial was conducted to evaluate TAG (ClinicalTrials.gov Identifier NCT03928717). Participants were randomized to receive TAG or a standard-of-care (SOC) control. All completed quantitative assessments on outcomes preintervention and at two follow-up visits at 6- and 12-months. TAG participants received personalized, semi-automated, and game-based text messages over the six-month intervention period. Primary outcomes included viral load, antiretroviral medication adherence, and missed HIV clinic visits. Secondary outcomes were also explored. Two surveys measured intervention acceptability. 60 YPWH were enrolled. 51 completed all assessments. At the 12-month follow-up assessment, TAG had a significant and positive effect on a measure of antiretroviral adherence but not viral load or missed clinic visits. Positive intervention effects were also found at postintervention and 12 months for several secondary outcomes (e.g., adherence-related social support). Intervention acceptability was generally high. TAG is a novel and promising mobile health intervention approach. Results suggest the need to further develop TAG as it may have the potential to reach populations of YPWH and improve HIV continuum of care outcomes in settings where access to more advanced mobile technology (e.g., smartphones) and the internet is not universal.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Adaptive Antiretroviral Therapy Adherence Intervention for Youth with HIV Through Text Message and Cell Phone Support with and without Incentives: A Sequential Multiple Assignment Randomized Trial (SMART).","authors":"Marvin E Belzer, Karen MacDonell, Demetria Cain, Samiran Ghosh, Richard Zhao, Julie McAvoy-Banerjea, Sitaji Gurung, Sylvie Naar","doi":"10.1007/s10461-024-04558-x","DOIUrl":"https://doi.org/10.1007/s10461-024-04558-x","url":null,"abstract":"<p><p>Youth living with HIV have low rates of medication adherence. Youth ages 15-24 years with adherence ≤ 80% or with HIV RNA PCRs (VL) ≥ 200 recruited through social media and clinical sites were randomized to brief weekday cell phone support (CPS) calls or daily, two-way, personalized text message (SMS) reminders for 3 months. Those with VL ≥ 200 or adherence ≤ 80% were rerandomized to receive SMS or CPS with monthly incentives for those utilizing the intervention at least 75% of days for 3 months. Those with VL < 200 or adherence > 80% after the initial 3 months were rerandomized to usual care or 3 months of tapered, 2x/week CPS or SMS. Self-reported adherence and VLs were collected every 3 months for one year. Eighty-three youth were recruited with 81% identifying as cisgender males, 55% Black, 22% Latine/x, and 76% gay, and 56% recruited from the Southern US. Both cohorts initially randomized to CPS and SMS demonstrated significant improvements in adherence over the 12-months (P <.001). Participants randomized to CPS had significant improvements in 7-day self-reported adherence over 12 months compared to those on SMS (P <.027). Those receiving a tapered intervention for an additional 3 months had improved self-reported adherence compared to those randomized to the standard of care arm (P <.001). Both SMS and CPS appear to be effective interventions for youth with poor antiretroviral adherence. Tapering the intervention for an additional 3 months is useful in maintaining adherence after the initial intervention. Additional research is required to determine how to best sequence these interventions, including the use of incentives.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Cultural Validation of the HIV Adolescent Readiness for Transition Scale (HARTS) in China.","authors":"Wenxi Zhong, Dan Tan, Xi Zhang, Jing Cheng, Bianchuan Cao, Jian Tang, Mei Liu, Song Fan, WeiLi Hu, Yanhua Chen","doi":"10.1007/s10461-024-04572-z","DOIUrl":"https://doi.org/10.1007/s10461-024-04572-z","url":null,"abstract":"<p><p>For adolescents infected with the Human Immunodeficiency Virus (HIV), transitioning from pediatric to adult healthcare requires thorough preparation to maintain care continuity and optimal health outcomes. In China, a dedicated scale for assessing their transition readiness is lacking. The HIV Adolescent Readiness for Transition Scale (HARTS) addresses this by evaluating transition readiness across vital domains, with its 15-item design predicting post-transition viral suppression-a key indicator of a successful transition. With no equivalent tool in China, the HARTS's cross-cultural adaptation holds significant potential for enhancing personalized transition strategies and health management. To validate the HIV Adolescent Readiness for Transition Scale (HARTS) among adolescents with HIV in China, the validation was conducted from October 2023 to February 2024, following a five-step process: translation and back-translation; content validity examination by 13 experts; pre-survey with 30 adolescents with HIV; test-retest reliability assessment with 40 adolescents with HIV over a 10-day interval; and structural validation using exploratory factor analysis, including principal component analysis and varimax orthogonal rotation, among 170 adolescents with HIV. The average content validity index of the scale was 0.99. The Cronbach's alpha value for the pre-survey was 0.767, and for test-retest reliability, the intra-class correlation coefficient (ICC) was 0.901. With a total of 15 items, the four factors that made up the scale-\"Disclosure,\" \"Health Navigation,\" \"Self-Advocacy,\" and \"Health Literacy\"-explained 81.73% of the variation. With alpha values of 0.940, 0.917, 0.929, and 0.888 for each of the four domains, the scale's overall Cronbach's alpha value was 0.943. The Chinese version of HARTS demonstrates good reliability and validity, serving as a tool for assessing the medical transition readiness level of adolescents with HIV in China.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Life Course Stressors, Latent Coping Strategies, Alcohol Use, and Adherence among People with HIV.","authors":"Amrita Gill, Gretchen Clum, Patricia Molina, David Welsh, Tekeda Ferguson, Katherine P Theall","doi":"10.1007/s10461-024-04570-1","DOIUrl":"https://doi.org/10.1007/s10461-024-04570-1","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive Symptoms and HIV Viral Suppression: A Systematic Review and Meta-analysis.","authors":"Bishan Huang, Alitasha Younger, Mary P Gallant, Thomas J O'Grady","doi":"10.1007/s10461-024-04571-0","DOIUrl":"https://doi.org/10.1007/s10461-024-04571-0","url":null,"abstract":"<p><p>Previous research suggests that depression impacts HIV outcomes, including viral suppression. This meta-analysis quantifies the association between depression and HIV viral suppression. A systematic literature search was conducted in PubMed, Web of Science, EBSCO, and OVID to identify studies published through 2012 to 2022. The software Rayyan was used to evaluate eligibility of studies, and the 2020 Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines were used for abstracting data. A random effects meta-analysis was performed using Review Manager 5.4.1. Of the 1911 articles screened, 16 studies were included covering 80,103 participants. The results showed individuals without depression were more likely to achieve HIV viral suppression or undetectable viral load compared to individuals with depression (OR 1.30; 95%CI 1.15, 1.48; I² = 76%). Subgroup analysis indicated this effect was significant among the general population of people living with HIV (n = 75,353; OR 1.32; 95%CI 1.12, 1.55; I² = 85%) and cisgender women living with HIV (n = 4553; OR 1.28; 95%CI 1.09, 1.50; I² = 16%), but not among cisgender men living with HIV (most identified as men who have sex with men) (n = 197; OR 2.13; 95%CI 0.43, 10.61; I² = 83%). This meta-analysis shows a significant positive association between the absence of depression and achieving HIV viral suppression overall and among the subgroup of cisgender women. Public health interventions for people living with HIV should include strategies to identify and address the depressive symptoms that impact adherence to treatment, increase the risk of psycho-behavioral co-morbidities, and exacerbate social or structural factors impeding viral suppression.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating Substance Use Homophily in the Sexual Network of a Large Cohort of Young Sexual and Gender Minorities Assigned Male at Birth.","authors":"Patrick Janulis, Gregory Phillips Ii, Cory Cascalheira, Brian Mustanski, Tom Wolff, Michelle Birkett","doi":"10.1007/s10461-024-04576-9","DOIUrl":"https://doi.org/10.1007/s10461-024-04576-9","url":null,"abstract":"<p><p>Young sexual and gender minority (SGM) people assigned male at birth who use substances are at elevated risk of HIV acquisition. This brief report leverages a large cohort of SGM people assigned male at birth to estimate substance use homophily (i.e., same-same substance use status) in sexual partnerships. We found substance use homophily in this sexual network for marijuana, poppers, methamphetamine, and hallucinogens but not heavy episodic drinking, cocaine, or ecstasy. These results suggest substance use is associated with sexual network structure and may increase HIV disparities between individuals who do and do not use substances.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Rapid Assessment Amid an Injection Drug Use-Driven HIV Outbreak in Massachusetts' Merrimack Valley: Highlights from a Case Study.","authors":"Sabrina S Rapisarda, Joseph Silcox, Patricia Case, Wilson R Palacios, Thomas J Stopka, Sofia Zaragoza, Jaclyn M W Hughto, Shikhar Shrestha, Traci C Green","doi":"10.1007/s10461-024-04567-w","DOIUrl":"https://doi.org/10.1007/s10461-024-04567-w","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between State Laws Regulating Minors' Access to Confidential Sexual Health Services and Lifetime HIV Testing Among U.S. Male High School Students.","authors":"Christina Aivadyan, Nabila El-Bassel, Mingway Chang, John Santelli, Morgan Philbin, Elwin Wu","doi":"10.1007/s10461-024-04574-x","DOIUrl":"https://doi.org/10.1007/s10461-024-04574-x","url":null,"abstract":"<p><p>Confidentiality concerns are a well-established barrier to sexual health services for adolescents. These barriers are likely even greater for young men who have sex with men (YMSM), who often experience stigma at multiple levels. This study examined the relationship between state laws regulating minors' access to confidential sexual health services, sexual behavior, and lifetime HIV testing among a large, representative sample of sexually active male high school students from the 2019 state-level Youth Risk Behavior Surveillance System (23 states; N = 17,509). We used multilevel logistic regression to examine whether confidentiality-promoting state laws (i.e., states that explicitly allowed minors to self-consent to HIV testing, did not have an age clause which set a minimum age to self-consent to sexual health services, did not permit parental notification, had confidentiality protections for insured dependents) were associated with lifetime HIV testing, and whether associations differed between YMSM (n = 1,718) and young men who have sex with women only (i.e., YMSWO; n = 15,791). After adjusting for individual- and state-level characteristics, HIV testing was significantly more likely for students in states that explicitly allowed minors to self-consent to HIV testing (adjusted odds ratio [aOR]: 1.12, 95% confidence interval [CI]: 1.05-1.21, p <.001), did not permit parental notification (aOR: 1.09, CI: 1.05-1.12, p <.001), or had confidentiality protections for insured dependents (aOR: 1.40, CI: 1.34-1.45, p <.001), and significantly less likely for those in states that lacked age clauses (aOR: 0.82, CI: 0.80-0.84, p <.001). We found no evidence for moderation of these associations by YMSM status (i.e., the effects of laws being confidentiality-promoting on HIV testing did not differ significantly for YMSM and YMSWO). Findings suggest that certain confidentiality-promoting state laws may be effective at increasing HIV testing among sexually active male adolescents, regardless of sexual behavior.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal Effects of Alcohol Consumption on Condom Negotiation Skills of Women with Varying Sexual Assault Histories.","authors":"Tina Zawacki, Terue T Vela, Sarah E Harper, Katie M Jackel","doi":"10.1007/s10461-024-04573-y","DOIUrl":"https://doi.org/10.1007/s10461-024-04573-y","url":null,"abstract":"<p><p>Sexual assault victimization experience and alcohol consumption are well-documented HIV risk factors for women who have sex with men (WSM). Nonetheless, behavioral mechanisms of the synergistic effects of these factors on women's increased HIV risk are not well delineated. This study is the first to examine the interactive effects of sexual assault history and acute intoxication on women's condom negotiation behavior during a face-to-face role-play with a male actor. Participants were female, single, social drinkers, ages 21 to 35, recruited from the community. Women were categorized as having experienced past sexual assault victimization or not based on their questionnaire responses, then were randomly assigned to consume either no alcohol or alcohol (0.08 target BAC) and engaged in a role-play with a male actor that included condom use negotiation. Participants' verbal, paraverbal, and nonverbal behavior was video recorded and coded by independent raters. As hypothesized, sexual assault history interacted with alcohol condition to significantly influence participants' assertive condom negotiation behavior. These results further our scientific understanding of how intoxication may exacerbate the relationship between sexual assault history and HIV risk, and can inform prevention programs tailored to the unique needs of WSM who have a history of sexual assault victimization and are social drinkers.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Nationally Representative Analysis of Substance Use and Sexual Health Correlates Associated with HIV and STI Testing among Adolescents.","authors":"Sitara M Weerakoon, Nimisha Srikanth, Christina Aivadyan, Bryce Puesta Takenaka, Raquel Rose, Jaleah D Rutledge, Xunyun Wan, Ijeoma Opara","doi":"10.1007/s10461-024-04575-w","DOIUrl":"https://doi.org/10.1007/s10461-024-04575-w","url":null,"abstract":"<p><p>Adolescents in the United States (US) continue to be disproportionately impacted by HIV and STIs. We investigated the associations between sexual health and substance use behaviors with HIV and STI testing among high school students in the US. Cross-sectional weighted stepwise multivariate logistic regression models were conducted to determine the odds of lifetime HIV and STI testing among students, stratified by sex. Drugs and alcohol before sex, condom use during sex, number of sex partners, sex of sexual partners, substance use (e-cigarette, alcohol, and cannabis) frequency, lifetime cocaine use, and lifetime prescription drug misuse were predictors, adjusting for race/ethnicity and age. This analysis used the 2019 and 2021 cycles of the CDC Youth Risk Behavioral Surveillance System (YRBSS) data. Our sample of adolescents (n = 30,909) had a mean age of 16; 51% were male. Females engaging in substance use had increased odds of HIV and STI testing whereas that pattern did not reflect among males. Multiracial male adolescents had increased odds of HIV testing. Females engaging in condomless sex had lower odds of HIV and STI testing. This study highlights the need for tailored HIV and STI testing promotion and ongoing efforts for dismantling barriers to testing services. Furthermore, our study suggests that screenings follow the concurrent nature of sexual health and substance use behaviors of adolescents for integrated HIV/STI testing.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}