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Validity and Reliability of the Kessler 6 Scale for Serious Mental Illness Among Populations with High Burden of HIV. HIV高负担人群严重精神疾病Kessler 6量表的效度和信度
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-27 DOI: 10.1007/s10461-025-04765-0
Rashunda Lewis, Monica Adams, Evelyn Olansky, Catlainn Sionean
{"title":"Validity and Reliability of the Kessler 6 Scale for Serious Mental Illness Among Populations with High Burden of HIV.","authors":"Rashunda Lewis, Monica Adams, Evelyn Olansky, Catlainn Sionean","doi":"10.1007/s10461-025-04765-0","DOIUrl":"https://doi.org/10.1007/s10461-025-04765-0","url":null,"abstract":"<p><p>The Kessler 6 (K6) scale has been widely used to screen for serious mental illness (SMI) in general populations. Given that populations with high burden of HIV may be more likely to experience poor mental health outcomes, it is important to validate measures used to assess SMI among these groups. Using data from CDC's National HIV Behavioral Surveillance (NHBS) system in the United States, we examined psychometric characteristics of the K6 scale, including exploratory factor analysis, scale reliability, construct validity, and review of interviewer feedback to explore scale performance in the field. Analyses confirmed a single factor structure and demonstrated that the K6 scale had high internal consistency and construct validity. Although interviewers noted that the effort item was difficult for some participants to understand, psychometric properties were not greatly improved with the deletion of the item. The results of this analysis suggest that the K6 scale is appropriate for use among NHBS populations with a high burden of HIV, including persons who inject drugs, heterosexually active adults at increased risk for HIV infection, women who exchange sex for money or drugs, and gay, bisexual, and other men who have sex with men.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Intersectional Stigma and Psychological Well-Being Among Men Who Have Sex with Men Living with HIV. 与艾滋病毒感染者发生性行为的男性中交叉污名与心理健康的关系
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-27 DOI: 10.1007/s10461-025-04795-8
Tianyue Mi, Xueying Yang, Guanghua Lan, Shan Qiao, Zhiyong Shen, Yuejiao Zhou, Xiaoming Li
{"title":"Association Between Intersectional Stigma and Psychological Well-Being Among Men Who Have Sex with Men Living with HIV.","authors":"Tianyue Mi, Xueying Yang, Guanghua Lan, Shan Qiao, Zhiyong Shen, Yuejiao Zhou, Xiaoming Li","doi":"10.1007/s10461-025-04795-8","DOIUrl":"https://doi.org/10.1007/s10461-025-04795-8","url":null,"abstract":"<p><p>Men who have sex with men (MSM) living with HIV face considerable psychosocial challenges, including stigma and discrimination, which may affect their mental health. Instead of considering each stigmatized identity in isolation, this study investigated the association between intersected HIV- and MSM-related stigma and psychological well-being of MSM living with HIV. Data of 402 MSM living with HIV were collected through a cross-sectional study in Guangxi, China, focusing on the association between HIV-/MSM-related stigma and HIV-related health outcomes among MSM living with HIV. Latent Moderated Structural Equations Approach was employed to examine the moderation effect of MSM-related stigma on the relationship between HIV-related stigma and mental health outcomes. The findings revealed that with a lower level of MSM-related stigma, the associations between HIV-related stigma and depression (β = 0.99, 95%CI [-0.63, 2.61], p = 0.23) or anxiety (β = 1.61, 95%CI [-0.44, 3.65], p = 0.12) were not significant; with a higher level of MSM-related stigma, the association between HIV-related stigma and depression (β = 3.32, 95%CI [1.67, 4.96], p < 0.001) or anxiety (β = 4.95, 95%CI [2.68, 7.22], p < 0.001) showed significant positive associations. The study demonstrates that higher levels of MSM-related stigma can intensify the relationship between HIV-related stigma and depression/anxiety among MSM. By emphasizing the role of intersectional stigma in adverse mental health outcomes, these findings will inform the development of effective and sustainable health strategies, policies, and services, including tailored mental health services and community-led stigma reduction programs aimed at the enhancement of well-being among MSM living with HIV.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Interplay of Social and Physical Factors in Risk Dynamics and Transitions Across the Life-Course of Female Sex Workers in Blantyre, Malawi: A Longitudinal Narrative Study. 探索社会和身体因素在马拉维布兰太尔女性性工作者生命历程中风险动态和过渡中的相互作用:一项纵向叙事研究。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-27 DOI: 10.1007/s10461-025-04790-z
Wezzie Stephanie Lora, Doreen Sakala, Amr Saidi, Wezzie Nyapigoti, Esnart Sanudi, Maryam Shahmanesh, Frances M Cowan, Joanna Busza, Nicola Desmond
{"title":"Exploring the Interplay of Social and Physical Factors in Risk Dynamics and Transitions Across the Life-Course of Female Sex Workers in Blantyre, Malawi: A Longitudinal Narrative Study.","authors":"Wezzie Stephanie Lora, Doreen Sakala, Amr Saidi, Wezzie Nyapigoti, Esnart Sanudi, Maryam Shahmanesh, Frances M Cowan, Joanna Busza, Nicola Desmond","doi":"10.1007/s10461-025-04790-z","DOIUrl":"https://doi.org/10.1007/s10461-025-04790-z","url":null,"abstract":"<p><p>Sexual risk amongst female sex workers (FSW) varies across the life-course and is influenced by socio-economic and interpersonal factors that affect behavioural choices and engagement in HIV/STI care. We explored transitions in the life-course of FSW to understand the dynamics of sexual risk in Blantyre, Malawi. We implemented a nested longitudinal qualitative study as part of the AMETHIST Consortium, a study testing approaches to reduce HIV transmission in sex work. We conducted consecutive narrative interviews with 30 FSW at three-time points over 12 months, with a three- to four-month break between each time point. We compared narratives to understand sex work transitions, HIV risk and engagement with HIV services. We identified factors (social and physical) related to sexual risk at the points of (1) transitions into sex work, (2) continuing sex work, and (3) breaks in sex work. At the entry stage, sexual risk was heightened when women lacked the knowledge and skills for protection against HIV/STI. Whilst continuing sex work, women's immediate financial needs were prioritised over their HIV/STI risk. These behaviours occurred whether they were aware of the associated HIV/STI risk. During breaks, women perceived lower risk and reduced engagement in prevention strategies, particularly when they had stable partners, which paradoxically increased their risk. These narratives reveal how social context informs and limits access to health care while concurrently promoting risky behaviours. A multifaceted and dynamically responsive approach that considers risk differentiation from a temporal perspective can strengthen targeted interventions, effectively addressing the multiple challenges faced by FSW.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Associated with Use of Protective Barriers Against HIV and Other Sexually Transmitted Infections During Sexual Behavior in Transmasculine and Nonbinary Adults from Argentina. 阿根廷跨性别和非二元性成年人在性行为中使用防护屏障预防艾滋病毒和其他性传播感染的相关因素
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-24 DOI: 10.1007/s10461-025-04762-3
Pablo D Radusky, Romina Caballero, Virginia Zalazar, Nadir Cardozo, Boris Brunori, Marcela Romero, Caro Mattie Dumas Pelletti, Ines Aristegui
{"title":"Factors Associated with Use of Protective Barriers Against HIV and Other Sexually Transmitted Infections During Sexual Behavior in Transmasculine and Nonbinary Adults from Argentina.","authors":"Pablo D Radusky, Romina Caballero, Virginia Zalazar, Nadir Cardozo, Boris Brunori, Marcela Romero, Caro Mattie Dumas Pelletti, Ines Aristegui","doi":"10.1007/s10461-025-04762-3","DOIUrl":"https://doi.org/10.1007/s10461-025-04762-3","url":null,"abstract":"<p><p>Evidence suggests a substantial burden of sexually transmitted infections (STIs) and high proportions of sexual behavior with no protective barriers in transmasculine and nonbinary individuals. However, research on this population's sexual health has been scarce, especially in the Latin American region. This study sought to determine the prevalence of self-reported STIs, and to explore correlates of use of protective barriers during sexual behavior among transmasculine and nonbinary individuals in Argentina. A sample of 304 participants responded to a questionnaire online to explore sociodemographic variables, history of HIV and other STIs, access to sexual and gender-affirming healthcare, and sexual behavior. Chi-square tests were calculated, and bivariate and multivariable logistic regression analyses were conducted to identify correlates of use of protective barriers during sexual behavior. Almost a quarter (23.4%) self-reported lifetime diagnosis of at least one STI and 63.8% did not use any protective barriers in their last sexual relation. Use of protective barriers during sexual behavior was negatively associated with insertive frontal/genital sexual behavior and with sex with cisgender women in the last month, and positively associated with ever attending a gynecologic examination, sex with cisgender men in the last month and lifetime transactional sex. Only these last two variables remained associated with use of protective barriers in the multivariable model. Use of protective barriers differs by type of sexual behavior and partner in transmasculine and nonbinary people. Sexual healthcare targeting this community should take this into consideration, and preventive interventions should be tailored to each individual's self-reported sexual behaviors.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intimate Partner Violence Perpetration and PrEP Use Among Sexual Minority Men: The Mediating Roles of Internalized Homonegativity and PrEP Stigma. 性少数男性亲密伴侣暴力行为与PrEP使用:内化同性恋负面性和PrEP污名的中介作用
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-24 DOI: 10.1007/s10461-025-04802-y
Erik D Storholm, Jessica Randazzo, Chenglin Hong, Daniel E Siconolfi, Carrie L Nacht, Sarita D Lee, Glenn J Wagner
{"title":"Intimate Partner Violence Perpetration and PrEP Use Among Sexual Minority Men: The Mediating Roles of Internalized Homonegativity and PrEP Stigma.","authors":"Erik D Storholm, Jessica Randazzo, Chenglin Hong, Daniel E Siconolfi, Carrie L Nacht, Sarita D Lee, Glenn J Wagner","doi":"10.1007/s10461-025-04802-y","DOIUrl":"https://doi.org/10.1007/s10461-025-04802-y","url":null,"abstract":"<p><p>Cisgender sexual minority men (SMM) report intimate partner violence (IPV) at rates comparable to or higher than heterosexual cisgender women, often linked to increased HIV risk. This study explores the relationship between IPV perpetration and pre-exposure prophylaxis (PrEP), considering the potential mediating effects of sexual orientation related minority stress and PrEP stigma. Utilizing baseline data from the Empowering Relationships and Opportunities for Safety (EROS) cohort, this cross-sectional study examined survey data from partnered cisgender SMM in the U.S. Through online and community recruitment, participants were assessed for IPV perpetration using a validated measure, while internalized homonegativity and related stigma were evaluated through standardized scales. Current PrEP use was assessed through self-report and confirmed through dried blood spot assays. Of the 500 participants, 125 (25%) reported IPV perpetration, with perpetration of identity-related IPV (e.g., threatening to out a partner to family or coworkers; telling partner to act straight) significantly higher among non-PrEP users; mean number of identity-related IPV perpetration items endorsed was 0.21 (SD = 0.53) among non-PrEP users compared to 0.02 (SD = 0.14) among PrEP users. Perpetration of identity-related IPV was positively correlated with internalized homonegativity (r =.19, p <.001), experienced sexual orientation discrimination (r =.15, p <.01), and PrEP stigma (r =.14, p <.001). A logistic regression mediation analysis found that, separately, internalized homonegativity (OR = 0.97, 95% CI [0.94-0.99]) and PrEP stigma (OR = 0.48, 95% CI [0.40, 0.57]) had significant associations with PrEP use, and that each mediated the relationship between perpetration of identity-related IPV and PrEP use as demonstrated by their significant indirect effects (OR = 0.88, 95% CI [0.78, 0.98] and (OR = 0.77, 95% CI [0.60, 0.98], respectively). The study underscores internalized homonegativity and PrEP stigma as critical mediators of the relationship between perpetration of identity-related IPV and PrEP use among SMM. Findings call for interventions aimed at reducing internalized homonegativity, PrEP stigma and enhancing PrEP access while addressing IPV dynamics. Future research should further delineate these pathways to inform culturally sensitive interventions promoting health equity among SMM.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Depression on Quality of Life among Women Living with HIV in Gondar Town, Northwest, Ethiopia, Prospective Cohort Study. 抑郁对埃塞俄比亚西北部Gondar镇艾滋病毒感染妇女生活质量的影响,前瞻性队列研究。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-24 DOI: 10.1007/s10461-025-04787-8
Tadele Amare Zeleke, Tadesse Awoke Ayele, Zewditu Abdissa Denu, Lillian Mwanri, Telake Azale
{"title":"Effect of Depression on Quality of Life among Women Living with HIV in Gondar Town, Northwest, Ethiopia, Prospective Cohort Study.","authors":"Tadele Amare Zeleke, Tadesse Awoke Ayele, Zewditu Abdissa Denu, Lillian Mwanri, Telake Azale","doi":"10.1007/s10461-025-04787-8","DOIUrl":"https://doi.org/10.1007/s10461-025-04787-8","url":null,"abstract":"<p><p>Depression is highly prevalent among women living with HIV (WLHIV) and is linked to poor quality of life (QoL), impaired functioning, and negative treatment outcomes. While studies in high-income settings report strong associations between depression, stigma, social support, and QoL, evidence from low-resource contexts such as Ethiopia remains limited. This study examined the relationship between depression and QoL among 627 WLHIV on stable antiretroviral therapy (ART) for at least six months. Data were collected prospectively at three-month intervals between September 2023 and April 2024 using structured interviews. Validated tools assessed depression (PHQ-9), HIV-related stigma, social support (Oslo scale), and QoL (WHOQOL-HIV BREF-Eth-27). Repeated measures ANOVA and linear mixed-effects models evaluated QoL trajectories and the impact of depression while adjusting for confounders. Depression was significantly associated with lower scores across all QoL domains: general (β = -0.06, p = 0.000), physical (β = -0.22, p = 0.000), psychological (β = -0.25, p=), spiritual (β = -0.08, p = 0.000), independence (β = -0.13, p = 0.000), environmental (β = -0.23, p = 0.000), and social (β = -0.09, p = 0.000). Non-adherence to ART also negatively affected multiple domains, including general (β = -0.28, p = 0.035), physical (β = -0.51, p = 0.031), psychological (β = -0.72, p = 0.003), social (β = -0.50, p = 0.006), and environmental (β = -0.97, p = 0.015). HIV-related stigma reduced QoL in six domains, while greater social support was positively associated with all domains. These findings underscore the urgent need to address depression, stigma, and ART adherence while promoting social support to improve QoL among WLHIV in Ethiopia.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive Coping, Psychological Distress, and Medication Adherence Among People Living with HIV/AIDS in Henan, China: A Moderated Mediation Analysis. 积极应对、心理困扰与河南HIV/AIDS患者药物依从性:一个有调节的中介分析
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-24 DOI: 10.1007/s10461-025-04771-2
Siwei Hou, Chenguang Du, Liang He, Qinying Wang, Yuting Xia, Guifeng Ding, Bin Zhang, Liran Xu, Hanzhang Xu
{"title":"Positive Coping, Psychological Distress, and Medication Adherence Among People Living with HIV/AIDS in Henan, China: A Moderated Mediation Analysis.","authors":"Siwei Hou, Chenguang Du, Liang He, Qinying Wang, Yuting Xia, Guifeng Ding, Bin Zhang, Liran Xu, Hanzhang Xu","doi":"10.1007/s10461-025-04771-2","DOIUrl":"https://doi.org/10.1007/s10461-025-04771-2","url":null,"abstract":"","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized Controlled Trial of a Couples-Based HIV Intervention for Transgender Women and Their Partners: Findings from the "It Takes Two" Project. 基于夫妻的跨性别女性及其伴侣艾滋病干预的随机对照试验:来自“两个人”项目的发现。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-24 DOI: 10.1007/s10461-025-04798-5
Kristi E Gamarel, Don Operario, Ellen S Stein, Lance M Pollack, Torsten B Neilands, Breonna McCree, Jack Johnson, Wesley M Correll-King, David Olem, Mallory O Johnson, Jae M Sevelius
{"title":"Randomized Controlled Trial of a Couples-Based HIV Intervention for Transgender Women and Their Partners: Findings from the \"It Takes Two\" Project.","authors":"Kristi E Gamarel, Don Operario, Ellen S Stein, Lance M Pollack, Torsten B Neilands, Breonna McCree, Jack Johnson, Wesley M Correll-King, David Olem, Mallory O Johnson, Jae M Sevelius","doi":"10.1007/s10461-025-04798-5","DOIUrl":"https://doi.org/10.1007/s10461-025-04798-5","url":null,"abstract":"<p><p>\"It Takes Two\" is a couples-based HIV prevention program designed for transgender women and their partners. The aim of this project is to alleviate HIV vulnerability by enhancing communication, improving shared goals, and decreasing relationship stigma. From November 2019 to November 2022, we conducted a randomized controlled trial with 52 couples (104 individuals). Participants were randomized into one of two groups: the intervention group received four 1-hour counseling sessions, while the control group received educational videos. Due to the COVID-19 pandemic, 60% of participants took part in a fully digital trial, including telehealth counseling. Assessments were conducted at baseline and at 3, 6, 9, and 12 months. We analyzed the outcomes using multilevel random coefficient models. While the intervention did not significantly impact HIV vulnerability, communication, or shared goals, there were reductions in relationship stigma among partners of transgender women at 3- (Cohen's d = 0.54), 6- (Cohen's d = 0.57), and 12-months (Cohen's d = 0.72) post-intervention. These findings highlight the importance of addressing relationship stigma and involving partners in HIV prevention efforts to promote the health of transgender women.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pilot Results of Masibambisane: Couples Motivational Interviewing with Mobile Breathalyzers to Address Unhealthy Drinking and Adherence to Antiretroviral Therapy in South Africa. Masibambisane的试点结果:在南非用移动酒精测试仪对不健康饮酒和坚持抗逆转录病毒治疗的夫妇进行动机性访谈。
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-24 DOI: 10.1007/s10461-025-04804-w
Amy A Conroy, Rita M Butterfield, Buyisile Chibi, Judith A Hahn, Torsten B Neilands, Lindani Msimango, Alastair van Heerden, Hilton Humphries, Tyrel J Starks
{"title":"Pilot Results of Masibambisane: Couples Motivational Interviewing with Mobile Breathalyzers to Address Unhealthy Drinking and Adherence to Antiretroviral Therapy in South Africa.","authors":"Amy A Conroy, Rita M Butterfield, Buyisile Chibi, Judith A Hahn, Torsten B Neilands, Lindani Msimango, Alastair van Heerden, Hilton Humphries, Tyrel J Starks","doi":"10.1007/s10461-025-04804-w","DOIUrl":"https://doi.org/10.1007/s10461-025-04804-w","url":null,"abstract":"<p><p>We evaluated the feasibility, acceptability, and preliminary efficacy of couples motivational interviewing (MI) with and without mobile breathalyzers (Masibambisane) to reduce unhealthy alcohol use among couples with HIV in KwaZulu-Natal, South Africa. Ninety couples were randomized to couples MI with breathalyzers (MI-plus), couples MI without breathalyzers (MI-only), or enhanced usual care (EUC). Eligible couples had at least one partner on antiretroviral therapy (ART) with a positive AUDIT-C screen. Primary outcomes included retention, session attendance, breathalyzer completion, and satisfaction rates. Exploratory outcomes were unhealthy alcohol use (i.e., positive AUDIT-C screen and/or phosphatidylethanol [PEth] ≥ 35 ng/ml), number of drinking days in past month, AUDIT-C score, optimal adherence to ART (95% or higher), and viral suppression. Retention and attendance rates were 97.7% and 83.3% at 6-months. Breathalyzer completion was limited (58.2%) due to cellular and power challenges. Satisfaction exceeded 94.8%. MI-only and MI-plus arms had larger declines in drinking days and AUDIT-C score and larger increases in ART adherence vs. EUC. We observed no differences in biomarker-confirmed unhealthy alcohol use, which remained high across all arms at two months (94.6%, 96.5%, and 100%) for EUC, MI-only, and MI-plus. Viral suppression rates were 86.7%, 96.5%, and 86.2% for EUC, MI-only, and MI-plus. Between-arm differences for outcomes were non-significant; however, moderation analysis revealed that MI-only (p < 0.001) and MI-plus (p < 0.016) significantly reduced AUDIT-C scores for those with severe drinking (AUDIT-C > 7). Masibambisane was highly feasible and acceptable. Results provide initial evidence of couples MI with breathalyzers to reduce alcohol use among those with very high-risk drinking.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics Associated with HIV Testing Frequency Among Gay and Bisexual Cisgender Men Who Have Sex with Men in the United States: Cross-sectional Study. 美国男同性恋和双性恋男同性恋者中HIV检测频率的相关特征:横断面研究
IF 2.7 2区 医学
AIDS and Behavior Pub Date : 2025-06-17 DOI: 10.1007/s10461-025-04800-0
Xaviera Villarino, Travis Sanchez, Cristian Acero Martinez, Stefan Baral, Iaah L Lucas, Sarah M Murray, Amrita Rao, Michael Smith, Mariah Valentine-Graves, Jeb Jones
{"title":"Characteristics Associated with HIV Testing Frequency Among Gay and Bisexual Cisgender Men Who Have Sex with Men in the United States: Cross-sectional Study.","authors":"Xaviera Villarino, Travis Sanchez, Cristian Acero Martinez, Stefan Baral, Iaah L Lucas, Sarah M Murray, Amrita Rao, Michael Smith, Mariah Valentine-Graves, Jeb Jones","doi":"10.1007/s10461-025-04800-0","DOIUrl":"https://doi.org/10.1007/s10461-025-04800-0","url":null,"abstract":"<p><p>Current HIV testing recommendations for sexually active gay and bisexual men who have sex with men (GBMSM) are to test for HIV annually. However, some GBMSM might benefit from more frequent HIV testing. We conducted a cross-sectional, online survey of cisgender GBMSM across the United States. Data collection occurred from October 2022-October 2023. Participants reported demographic information, sexual behavior, and HIV testing frequency over the past 2 years. HIV testing frequency was categorized as less than annual, annual, or greater than annual. We examined demographic, behavioral, mental health, and stigma correlates of HIV testing frequency among respondents without a history of pre-exposure prophylaxis (PrEP) use. Of 1972 GBMSM included in the analysis, 1171 (59%), 379 (19%), and 422 (21%) reported less than annual, annual, and greater than annual HIV testing, respectively. Hispanic and non-Hispanic Black GBMSM, who experience the highest HIV incidence among GBMSM, were likely to test more frequently than non-Hispanic White GBMSM. More frequent testing was also associated with PrEP eligibility; less frequent testing was associated with living in a non-urban area. More frequent HIV testing was reported by groups that experience higher HIV incidence and by those who had indications for PrEP, indicating that HIV testing frequency aligns with need for many GBMSM. More efforts are needed to increase HIV testing among GBMSM who test less frequently, including those living in rural areas.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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