AIDS and Behavior最新文献_第2页

Attitudes Towards Aging, Depression, Physical Functioning, and Pain Among Women Living with HIV of Reproductive Age. 育龄期HIV感染者对衰老、抑郁、身体功能和疼痛的态度

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-05-06 DOI: 10.1007/s10461-025-04724-9

Emily M Cherenack, Theodora F Brophy, Margarita Avila Max, Alicia Graubard-Silebi, Nicholas F Nogueira, Yue Pan, Daniel Westreich, Elizabeth F Topper, Deborah Konkle-Parker, Aadia Rana, Seble G Kassaye, Anandi N Sheth, Deborah L Jones, Maria L Alcaide

{"title":"Attitudes Towards Aging, Depression, Physical Functioning, and Pain Among Women Living with HIV of Reproductive Age.","authors":"Emily M Cherenack, Theodora F Brophy, Margarita Avila Max, Alicia Graubard-Silebi, Nicholas F Nogueira, Yue Pan, Daniel Westreich, Elizabeth F Topper, Deborah Konkle-Parker, Aadia Rana, Seble G Kassaye, Anandi N Sheth, Deborah L Jones, Maria L Alcaide","doi":"10.1007/s10461-025-04724-9","DOIUrl":"https://doi.org/10.1007/s10461-025-04724-9","url":null,"abstract":"Positive attitudes towards aging (ATA) are associated with better mental and physical health in the general population and with lower depressive symptoms among men living with HIV. Little is known about ATA among women of reproductive age living with HIV (WWH), who often experience premature aging, depression, and chronic pain. This study examined the association of ATA with HIV, physical functioning, and pain among women 19-45 years-of-age. From 2021 to 2022, survey data were collected at baseline from 143 WWH and 39 women without HIV (WWOH) across the southern United States; 94 WWH also completed a six-month follow-up visit. Baseline ATA was compared across HIV status. Among WWH, correlations between ATA, participant factors relevant in prior research (i.e., age, depression, illness), pain, and physical functioning were examined. Regressions examined the association of baseline ATA with physical functioning and pain across visits, including when controlling for potential confounders. Having one or more negative ATA was reported by an equal proportion of WWH (57%) and WWOH (58%). Among WWH, more positive ATA correlated with lower depressive symptoms, better physical functioning, and lower pain at baseline. Lower depressive symptoms correlated with better physical functioning and lower pain at baseline. In regressions, more positive ATA was associated with better physical functioning at baseline and follow-up. A weak association of ATA with pain at baseline was not significant at follow-up or after controlling for depression. Research is warranted to examine how combined interventions to improve ATA, depression, and pain can support well-being among reproductive-aged WWH.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

UNAIDS 90-90-90 Target and Retention in Care of a Cohort of Migrants Living with HIV in a Tertiary Referral Hospital in Florence, Italy. 联合国艾滋病规划署90-90-90：意大利佛罗伦萨一家三级转诊医院对一批感染艾滋病毒的移民的目标和保留。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-05-06 DOI: 10.1007/s10461-025-04716-9

Giuseppe Gasparro, Sasha Trevisan, Seble Tekle Kiros, Costanza Malcontenti, Michele Trotta, Anna Barbiero, Beatrice Borchi, Filippo Bartalesi, Paola Corsi, Costanza Fiorelli, Gaetana Sterrantino, Alessandro Bartoloni, Filippo Lagi

{"title":"UNAIDS 90-90-90 Target and Retention in Care of a Cohort of Migrants Living with HIV in a Tertiary Referral Hospital in Florence, Italy.","authors":"Giuseppe Gasparro, Sasha Trevisan, Seble Tekle Kiros, Costanza Malcontenti, Michele Trotta, Anna Barbiero, Beatrice Borchi, Filippo Bartalesi, Paola Corsi, Costanza Fiorelli, Gaetana Sterrantino, Alessandro Bartoloni, Filippo Lagi","doi":"10.1007/s10461-025-04716-9","DOIUrl":"https://doi.org/10.1007/s10461-025-04716-9","url":null,"abstract":"Migrant Living with HIV (MLWH) are facing many barriers. Proposing targeted interventions requires a better understanding of the local epidemiology, but data are scarce. This population often comprises vulnerable groups such as men who have Sex with men and transgender individuals. This single-center cohort study aims to estimate the achievement of the Joint United Nations Programme on HIV/AIDS 90-90-90 goals and the 8-year loss-to-follow-up (LTFU) incidence rate in a cohort of MLWH under treatment at the Infectious and Tropical Diseases Unit of the \"Careggi University Hospital\", Florence, Italy. We enrolled MLWH taken in care from 01/01/2014 to 31/12/2022. The end of the study was the end of follow-up (30/04/2023) or the date of LTFU (unreachable, relocated to another center, or dead). We enrolled 201 migrants with a median age of 33 [IQR 27-43]. One-hundred-and-six (52.7%) came from Latin America, mainly from Peru (40.2%; n = 81). About a third were transgender women (TW) (32.8%; n = 66). Seventy-six (37.8%) were migrants out-of-status (MOS). HIV was diagnosed in Italy in 58.7% (n = 118). Ninety (44.8%) were treatment-naïve, sex-working was reported in 39 patients (19.4%) before and 55 (27.4%) after migration. One-hundred-thirty-eight (68.7%) were retained in care. The 8-year-LTFU incidence rate was 8.96 per 100 p/y (95% CI 7.0-11.4). MOS had a higher risk of LTFU (aHR 2.68; p = 0.005). Conversely, being a TW (aHR 0.33; p = 0.024) and taking a single-tablet-regimen (aHR 0.44; p = 0.008) were protective factors.In our setting the 90-90-90 targets have not yet been fully achieved, and high rates of LTFU have been observed.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences Between Rural and Urban America that Inform HIV Prevention Messaging. 美国农村和城市艾滋病预防信息的差异。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-05-06 DOI: 10.1007/s10461-025-04710-1

Pamela A Williams, Jennifer D Uhrig, Brittany A Zulkiewicz, Mihaela Johnson, Stefanie K E Anderson, Euna M August

{"title":"Differences Between Rural and Urban America that Inform HIV Prevention Messaging.","authors":"Pamela A Williams, Jennifer D Uhrig, Brittany A Zulkiewicz, Mihaela Johnson, Stefanie K E Anderson, Euna M August","doi":"10.1007/s10461-025-04710-1","DOIUrl":"https://doi.org/10.1007/s10461-025-04710-1","url":null,"abstract":"HIV prevention efforts have traditionally focused on urban areas, yet about one-fourth of new HIV diagnoses in the U.S. are in non-urban areas. This study explored rural and urban differences in perceived HIV risk; perceived HIV stigma; and pre-exposure prophylaxis (PrEP) awareness, attitudes, beliefs, communication behaviors, and use to inform the development of communication messages to promote informed decision-making among available HIV prevention options, including PrEP. We conducted interviews, preceded by a brief survey, with 255 adults in 5 rural and 6 urban locations throughout the U.S. with high HIV burden. Participants from rural areas more frequently described their risk of getting HIV as low compared with those from urban areas, although partly due to differences in gender/sexual identity and sexual risk. Participants from rural areas more frequently reported perceived stigma around getting tested for HIV, taking PrEP to prevent HIV, or having HIV and less frequently reported having heard of PrEP and having a healthcare provider talk with them about PrEP compared with those from urban areas. No participants from rural areas reported using PrEP, although 48% of those with HIV-negative or unknown status were at substantial risk based on reported risk factors. Our findings highlight notable differences in perceived HIV risk; perceived HIV stigma; and PrEP awareness, attitudes, beliefs, communication behaviors, and use between individuals residing in rural and urban areas, suggesting that HIV prevention messaging needs to be tailored for rural audiences to support receptivity.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neighborhood Disadvantage, Syndemic Conditions, and PrEP Non-Adherence in Young Sexual and Gender Minority Men. 年轻性少数和性别少数男性的社区劣势、疾病条件和不遵守PrEP。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-05-06 DOI: 10.1007/s10461-025-04722-x

Michael P Williams, Justin Manjourides, Louisa H Smith, Crissi B Rainer, Lisa Hightow-Weidman, Danielle F Haley

{"title":"Neighborhood Disadvantage, Syndemic Conditions, and PrEP Non-Adherence in Young Sexual and Gender Minority Men.","authors":"Michael P Williams, Justin Manjourides, Louisa H Smith, Crissi B Rainer, Lisa Hightow-Weidman, Danielle F Haley","doi":"10.1007/s10461-025-04722-x","DOIUrl":"https://doi.org/10.1007/s10461-025-04722-x","url":null,"abstract":"Adherence to Pre-Exposure Prophylaxis (PrEP) among young sexual and gender minority men who have sex with men (YSGMMSM) has been suboptimal for reducing HIV incidence in the United States. Using the syndemic framework, the present study characterized how neighborhood disadvantage and clustering of two or more syndemic conditions (depression, anxiety, polysubstance use, history of arrest, BIPOC racial identity, unemployment) was related to PrEP non-adherence among 212 YSGMMSM aged 16-24. This study is a secondary analysis of an efficacy trial testing a PrEP adherence digital intervention for YSGMMSM combining participant survey and biological PrEP adherence data with measures of neighborhood disadvantage. Using multilevel models, we found that YSGMMSM residing in high-disadvantage neighborhoods were 2.79 (CI = 1.11, 7.00) times more likely to have a cluster of syndemic conditions compared to those in low-disadvantage neighborhoods. YSGMMSM residing in high-disadvantage neighborhoods were 3.14 (OR = 3.14, CI = 1.17, 8.44) times more likely to be PrEP non-adherent. YSGMMSM with two or more syndemic conditions were 2.64 (CI = 1.01, 6.94) times more likely to be PrEP non-adherent compared to those with 0 or 1 condition. Among participants living in high-disadvantage neighborhoods, 38% had a cluster of a syndemic conditions compared 20% in low-disadvantage neighborhoods. Despite this, neighborhood disadvantage did not significantly moderate the relationship between clustering of syndemic conditions and PrEP non-adherence among YSGMMSM. Further research into multilevel syndemic influences on PrEP adherence is needed to develop strategies for improving HIV vulnerability among YSGMMSM.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing PrEP Initiation and Adherence Among High-Risk, Sexually Active Adolescents and Young Adults: A Population-Based Prospective Study Across Diverse Service Delivery Models in a High HIV Prevalent District in South Africa. 评估高危、性活跃的青少年和年轻人的PrEP启动和依从性：一项基于人群的前瞻性研究，在南非一个艾滋病毒高发地区采用不同的服务提供模式。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-05-02 DOI: 10.1007/s10461-025-04719-6

Edward Nicol, Wisdom Basera, Eunice Turawa, Carl Lombard, Noluntu Funani, Dakalo Chavhalala

{"title":"Assessing PrEP Initiation and Adherence Among High-Risk, Sexually Active Adolescents and Young Adults: A Population-Based Prospective Study Across Diverse Service Delivery Models in a High HIV Prevalent District in South Africa.","authors":"Edward Nicol, Wisdom Basera, Eunice Turawa, Carl Lombard, Noluntu Funani, Dakalo Chavhalala","doi":"10.1007/s10461-025-04719-6","DOIUrl":"https://doi.org/10.1007/s10461-025-04719-6","url":null,"abstract":"Pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy for high-risk populations, including adolescent girls and young women (AGYW) and adolescent boys and young men (ABYM). While various PrEP-delivery models exist in South Africa, little is known about optimizing PrEP-uptake and adherence for AGYW and ABYM. This study explored preferred and feasible PrEP care models to enhance initiation and adherence among at-risk adolescents and young adults (AYAs) in a high-HIV prevalent rural district in South Africa. We conducted a longitudinal, population-based cohort study from August 2021 to July 2022 across 22 service delivery points (SDPs) in KwaZulu-Natal. High-risk, sexually active HIV-negative AGYW (15-24 years) and ABYM (15-35 years) were recruited from clinics, schools, and community-based youth zones. PrEP-uptake and adherence, based on national guidelines, were assessed using Pearson's Chi square test and binomial regression. Of 2,772 HIV-negative AYA, 781 (28%) initiated PrEP. Despite 65% being classified as high risk for HIV (p < 0.001), only 22% initiated PrEP. Initiation was higher in female (82%, p < 0.001) and among the 15-19 years (51%, p = 0.11). PrEP uptake varied significantly by SDPs, lowest in clinics (9%, p < 0.001), higher in youth zones (58%, p < 0.001), and highest in schools (73%, p < 0.001). Adherence declined significantly over time, dropping from 12% at one month to 2% at six months (p < 0.001). These findings highlight the need for targeted interventions in schools and communities, addressing barriers such as awareness, side effects, and accessibility. Expanding PrEP services to non-traditional settings may enhance uptake and adherence, reducing HIV risk among young people.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Competing Risks Duration Model to Study PrEP Discontinuation Among MSM in France: The ERAS 2023 Study. 一个竞争风险持续时间模型研究PrEP停止在法国的MSM: ERAS 2023研究。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-04-30 DOI: 10.1007/s10461-025-04729-4

Clément Boutet, Marion Di Ciaccio, Bruno Spire, Annie Velter, Luis Sagaon-Teyssier

{"title":"A Competing Risks Duration Model to Study PrEP Discontinuation Among MSM in France: The ERAS 2023 Study.","authors":"Clément Boutet, Marion Di Ciaccio, Bruno Spire, Annie Velter, Luis Sagaon-Teyssier","doi":"10.1007/s10461-025-04729-4","DOIUrl":"https://doi.org/10.1007/s10461-025-04729-4","url":null,"abstract":"Although PrEP prevents HIV among at-risk populations, high discontinuation rates hinder its effectiveness. We investigated three reasons for PrEP discontinuation in real-life settings in France and associated factors, in order to assess weariness taking PrEP. We used data from the French online survey Enquête Rapport au Sexe 2023 which targeted gay and bisexual men having sex with men (GBMSM). First, we constructed the outcome 'PrEP duration'. Second, we created a three-category 'reason for PrEP discontinuation' variable as follows: changes in sexual behaviors, a desire to discontinue PrEP, and clinical reasons. Third, we calculated PrEP survival probability. We then performed a Weibull accelerated failure time model with competing risks to assess how the duration of time on PrEP influenced discontinuation, and whether specific factors were associated with different discontinuation reasons. The analysis included 4819 GBMSM. Median PrEP duration was 19 months. Discontinuation because of changes in sexual behaviors was less likely among GBMSM who initiated PrEP prescription in a sexual health structure (AF = 0.604 [0.424-0.858]). A desire to stop PrEP was more likely among those living in regions with the lowest reported seropositivity rates (AF = 2.320 [1.054-5.107]). Discontinuing PrEP for clinical reasons was more likely among participants coming from smaller municipalities (AF = 2.312 [1.099-4.868]). PrEP duration dependence was negative for all three reasons, implying that the longer the time taking PrEP, the lower the probability of discontinuation. We found no weariness with PrEP use among GBMSM; this highlights the need to detail specific factors associated with PrEP discontinuation.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Booklet Self-Help Intervention for People Living with HIV and Depressive Symptoms in Botswana: A Randomized Controlled Trial. 博茨瓦纳艾滋病毒和抑郁症患者自助干预手册：一项随机对照试验。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-04-29 DOI: 10.1007/s10461-025-04742-7

Boitumelo Vavani, Nadia Garnefski, Sanne van Luenen, Elise Dusseldorp, Kennedy Amone-P'Olak, Philip Spinhoven, Vivian Kraaij

{"title":"A Booklet Self-Help Intervention for People Living with HIV and Depressive Symptoms in Botswana: A Randomized Controlled Trial.","authors":"Boitumelo Vavani, Nadia Garnefski, Sanne van Luenen, Elise Dusseldorp, Kennedy Amone-P'Olak, Philip Spinhoven, Vivian Kraaij","doi":"10.1007/s10461-025-04742-7","DOIUrl":"https://doi.org/10.1007/s10461-025-04742-7","url":null,"abstract":"In low- and middle-income countries (LMICs), there is a scarcity of psychological treatment options for people living with HIV (PLWH) with depressive symptoms. Self-help programs for depressive symptoms, in particular, are cost-effective and scalable, and therefore a promising tool in the treatment of depressive symptoms for people in low-resourced countries. This paper presents the results of a study that examined the effectiveness of a guided self-help program in reducing depressive symptoms in PLWH in Botswana. A Randomized Controlled Trial (RCT) was conducted on a sample of PLWH who were screened at HIV treatment centers in Botswana. The RCT had two conditions: an intervention group that received the self-help program with coaching and an attention-only control group. In both groups, a pre-test, post-test, and 3-month follow-up measurement were administered. Patients in the intervention group followed a booklet Cognitive Behavioral Therapy (CBT)-based self-help program. Seventy-two participants were included in the study. The results indicated significantly larger decreases in depressive symptoms in the intervention group than in the attention-only control group, both in the short and longer term, with large effect sizes. In addition, there were significant reductions in anxiety symptoms in the intervention group compared to the control group. The user satisfaction was high. Implementing this low-cost and scalable self-help program in a LMIC such as Botswana is critical in bridging the existing mental health treatment gap. This clinical Trial was registered with the Netherlands Trial registry, number NTR5407on August 23, 2018.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical Activity, Cigarette Smoking, and Depression Among People with HIV. 艾滋病毒感染者的体育活动、吸烟和抑郁。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-04-29 DOI: 10.1007/s10461-025-04727-6

Nicholas J SantaBarbara, Melissa A St Hilaire, Deborah J Konkle-Parker, Warren Scott Comulada, Jennifer Cantrell, Amber D'Souza, Robert Foronjy, Susan L Koletar, Matthew J Mimiaga, Frank J Palella, Daniel Merenstein, Anna A Rubtsova, Sarath Raju, Claudia A Martinez, David B Hanna, M Bradley Drummond, Kathleen M Weber, Richard Wang, Kristine M Erlandson

{"title":"Physical Activity, Cigarette Smoking, and Depression Among People with HIV.","authors":"Nicholas J SantaBarbara, Melissa A St Hilaire, Deborah J Konkle-Parker, Warren Scott Comulada, Jennifer Cantrell, Amber D'Souza, Robert Foronjy, Susan L Koletar, Matthew J Mimiaga, Frank J Palella, Daniel Merenstein, Anna A Rubtsova, Sarath Raju, Claudia A Martinez, David B Hanna, M Bradley Drummond, Kathleen M Weber, Richard Wang, Kristine M Erlandson","doi":"10.1007/s10461-025-04727-6","DOIUrl":"https://doi.org/10.1007/s10461-025-04727-6","url":null,"abstract":"People with HIV (PWH) smoke cigarettes 2-3 times more and are 3 times more likely to have clinical depression relative to the general population. Physical activity (PA) can aid in smoking cessation and reduce depression in the general population; the role of PA for smoking cessation among PWH is unknown. Data collected between October 2021-September 2022 from the Multicenter AIDS Cohort Study (MACS)/Women Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) were analyzed using logistic regression and structural equation modeling to examine associations between cigarette smoking, PA and depression. Among adult PWH (n = 1584), 505 were insufficiently active (MET-min/week ≤ 500), 400 were currently smoking, and 420 had clinically significant depressive symptoms (CES-D ≥ 16). The odds of current smoking were significantly higher among PWH who were insufficiently active compared to sufficiently active, even after adjusting for age, sex, body mass index, race, ethnicity, substance use, and viral load (aOR = 1.40 [95% CI: 1.04-1.87], p = 0.03). Similarly, the odds of current smoking were significantly higher among PWH with more symptoms of depression in adjusted models (aOR = 1.57 [95% CI: 1.16-2.12], p = 0.003). When stratified by sex, the odds of current smoking remained significantly higher among female PWH, but not male PWH who were insufficiently active. The odds of current smoking also remained significantly higher among females but not males with more symptoms of depression. Structural equation modeling indicated that PA and depression have independent and direct effects on smoking among PWH. Physical inactivity and depression are associated with smoking, but longitudinal studies are needed to better understand directionality and causality.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of DEI on HIV Research. DEI对HIV研究的影响。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-04-29 DOI: 10.1007/s10461-025-04715-w

David M Stoff

引用次数: 0

Exercise Interventions Conducted Among Individuals with Co-occurring HIV and Unhealthy Substance Use: A Systematic Review. 在同时发生HIV和不健康物质使用的个体中进行的运动干预：一项系统综述。

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-04-28 DOI: 10.1007/s10461-025-04735-6

Colleen B Mistler, William Allen, Alyssa A Grimshaw, Christie I Idiong, Dini Harsono, Melinda L Irwin, Garrett Ash, Linda S Pescatello, Jaimie P Meyer, E Jennifer Edelman

{"title":"Exercise Interventions Conducted Among Individuals with Co-occurring HIV and Unhealthy Substance Use: A Systematic Review.","authors":"Colleen B Mistler, William Allen, Alyssa A Grimshaw, Christie I Idiong, Dini Harsono, Melinda L Irwin, Garrett Ash, Linda S Pescatello, Jaimie P Meyer, E Jennifer Edelman","doi":"10.1007/s10461-025-04735-6","DOIUrl":"10.1007/s10461-025-04735-6","url":null,"abstract":"Unhealthy substance use and physical inactivity are prevalent co-occurring risk factors for morbidity and mortality among people with HIV (PWH). Evidence-based exercise interventions targeting both risk factors are limited. We conducted a literature search across seven databases for relevant articles published through 05/07/24. Studies qualified if they involved: (a) PWH ≥ 18 years old who engage in unhealthy substance use; (b) randomized controlled trials (RCTs) or quasi-experimental designs; and (c) an exercise intervention. Two researchers independently completed the Cochrane Data Collection Form and Joanna Briggs Institute Critical Appraisal Tool. PROSPERO registry: CRD42023473582. Out of 6916 potentially qualifying studies, 46 underwent full-text review, and 7 studies qualified (6 pilot RCTs & 1 quasi-experimental). Most (k = 6) were conducted in the US. Sample sizes ranged from 16 to 73 participants and retention rates ranged from 42 to 100%. Interventions met at least 1x/week for 6-24 weeks and consisted of supervised progressive overload aerobic/resistance training (k = 3), home-based training with virtual behavioral counseling (k = 1), yoga (k = 2), and tai-chi with cognitive behavioral therapy (k = 1). Despite inconsistent assessment tools and outcomes measured, exercise interventions were significantly (p < 0.05) and positively associated with outcomes relating to improving HIV, substance use, physical activity, strength/fall risk, quality of life/stress, and pain relief. All studies were high quality with low risk of bias, safe, and feasible. Despite small sample sizes and heterogeneity across studies, evidence from this systematic review supports the use of exercise to improve a variety of health outcomes among PWH with unhealthy substance use.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0