AIDS and Behavior最新文献

{"title":"Perspectives of Traditional Healers, Religious Leaders, and Biomedical Providers on Depression and HIV Care in Rural Uganda.","authors":"Johanna C Hvalić-Mwase, Olivia Brill, Boxuan Song, Charlie Updegraff, Chloe Kim, Masika Mercy Masitula, Jesus Rivera-Zamudio, Allan Tukamushaba, Ritah Wafana Nabafu, Elmilca Thermidor, Alex Noah Jjingo, Gladys Namuluta, Robert Rosenheck, Alexander C Tsai, Yang Jae Lee","doi":"10.1007/s10461-026-05277-1","DOIUrl":"https://doi.org/10.1007/s10461-026-05277-1","url":null,"abstract":"<p><p>Access to depression care remains limited in rural Uganda, where individuals, particularly people living with HIV, often seek support from a range of community-based and biomedical providers. Yet little is known about how these providers conceptualize depression in the context of HIV or how their perspectives shape care. This study aimed to explore how biomedical providers, traditional healers, and religious leaders conceptualize depression, perceive one another's roles, and approach depression care for people living with and without HIV. We conducted a qualitative study in Buyende District, Uganda, including 60 in-depth interviews with biomedical providers, traditional healers, and religious leaders (20 per group). Data were analyzed using thematic analysis. Four themes emerged: conceptualizations of depression, perceptions of other providers, strategies for care, and barriers to treatment. Across provider groups, depression was understood as rooted in socioeconomic hardship and frequently linked to the challenges of living with HIV. Material support, livelihood opportunities, and counseling were widely viewed as central components of effective care. While biomedical providers were generally perceived as more legitimate, mistrust toward traditional healers was common. Despite differing explanatory models, participants described overlapping counseling practices and expressed interest in improved communication across provider groups. Participants also expressed concern that reductions in HIV funding could worsen economic insecurity and increase vulnerability to depression. These findings highlight how depression care for people living with HIV unfolds within pluralistic provider systems and underscore the importance of integrating psychosocial care with strategies that address economic vulnerability when designing HIV and mental health interventions in rural settings.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of an Extended Sexual Orientation and Gender Identity Measure in a Racially and Ethnically Diverse Cohort of People Living with or at Risk for HIV Infection.","authors":"Skylar J Gaughan, Phyllis C Tien, Juno Obedin-Maliver, Alexis Ceja, Nguyen K Tran, Rachel L Kaplan, Kathryn Anastos, Aruna Chandran, M Reuel Friedman, Olivia T Van Gerwen, Deborah L Jones, Jennafer Kwait, Igho Ofotokun, Annesa Flentje","doi":"10.1007/s10461-026-05263-7","DOIUrl":"https://doi.org/10.1007/s10461-026-05263-7","url":null,"abstract":"<p><p>Despite becoming a routine part of clinical care, collection of sexual orientation and gender identity (SOGI) is not standardized, and common measures might not reflect the full range of LGBTQ+ experiences. In this study, we tested a novel expanded SOGI measure that addresses these concerns in a racially and ethnically diverse HIV cohort study. Participants (N = 885) were randomized to complete either a common SOGI measure with fewer SOGI choices or an expanded SOGI measure with more response options. We assessed the sensitivity, specificity, positive and negative predictive values, and area under the curve of the receiver operating characteristic, comparing the common and expanded SOGI measures against a single LGBTQ+ identity question serving as the reference standard. We conducted the DeLong test to evaluate differences in the area under the curve between the common and expanded measures. The expanded measure had a sensitivity of 98.5% and a specificity of 81.2% for identifying LGBTQ+ participants. The common measure had a sensitivity of 99.2% and a specificity of 83.3%. The DeLong test yielded no statistically significant difference between these measures. This pattern persisted across most demographic groups, except for Black or African American participants, and participants in middle adulthood (41-60 years). There was no difference in participant discomfort in answering the questions in each measure. Collecting accurate SOGI information is crucial given persistent HIV-related healthcare disparities in LGBTQ+ populations.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prior-Year Substance Use Disorders and Subsequent HIV Retention in Care Among Men Living with HIV Who Have Sex with Men.","authors":"Syeda Shehirbano Akhtar, Pieter Baker, Yichen Li, Jiajia Zhang, Bankole Olatosi","doi":"10.1007/s10461-026-05268-2","DOIUrl":"https://doi.org/10.1007/s10461-026-05268-2","url":null,"abstract":"<p><p>Substance use disorders (SUDs) and polysubstance use (defined as co-occurring SUDs involving two or more substances), precursors for high-risk behaviors among key populations like men who have sex with men (MSM), may significantly impede optimal engagement in the HIV care continuum. Leveraging 14 years of Electronic Health Record (EHR) data (2006-2020) from a retrospective population-based cohort in South Carolina, we fitted logistic GLMMs with patient-level random intercepts to estimate lagged associations between prior-year SUD diagnoses and subsequent-year retention in care among 5183 MSM living with HIV. HIV retention in care status was defined as having at least two VL/CD4 tests at least 90 days apart within 365 days. Our findings include the following: (1) Retention in care decreased between baseline (74%) and year 10 (49%); (2) Any prior-year SUD was significantly associated with decreased odds of subsequent-year retention in care (OR [95% CI] = 0.85 [0.75-0.96]); (3) In adjusted models, age was a strong independent predictor of retention in care, with a protective effect among older age groups aged 31-40 years (OR [95% CI]= 1.75 [1.44-2.11]), 41-50 years (OR [95% CI] = 2.04 [1.64-2.53]), 51-60 years (OR [95% CI] = 3.03 [2.15-4.27]), and over 60 (OR [95% CI] = 2.56 [1.36-4.83]); and (4) Prior-year substance-specific SUDs and polysubstance use were not significantly associated with subsequent-year retention in care, diminishing the significant effect observed when SUD was modeled as \"any SUD\". Results suggest that addressing substance use disorder, in particular among young MSM, is critical for coordinating efforts and informing policy decisions to improve HIV retention in care, an enduring challenge for Southeastern US states like South Carolina.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148787121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Mobile Counseling Program for Gay and Bisexual Men's Mental, Behavioral, and Sexual Health in Eastern Europe: A Randomized Controlled Trial.","authors":"Corina Lelutiu-Weinberger, Mircea L Filimon, Anna M Zavodszky, Donald R Hoover, Roberta Scheinmann, Mihai Lixandru, Lucian Hanu, Bogdan Dogaru, Jillian R Scheer, Ilana Seager van Dyk, Cristian Dorobantescu, Adrian Streinu-Cercel, John E Pachankis","doi":"10.1007/s10461-026-05274-4","DOIUrl":"https://doi.org/10.1007/s10461-026-05274-4","url":null,"abstract":"<p><p>In Romania, the HIV epidemic attributed to male-to-male sexual contact is high, due to multiple sociocultural manifestations of stigma toward gay, bisexual, and other men who have sex with men (GBM), which is associated with inadequate HIV prevention. The current analyses describe the results of an intervention aiming to reduce HIV risk and heavy alcohol use, and improve mental health and minority stress-related outcomes, among GBM in Romania. Between 2019 and 2023, 300 Romanian GBM reporting HIV risk and heavy alcohol use were randomized to receive eight 1-h text-based live counseling sessions (the Comunica condition) or self-directed online educational control modules, both informed by the Information-Motivation-Behavior (IMB) model and minority stress theory. Self-reported assessments were conducted at baseline and at 4-, 8-, and 12-month follow-ups; HIV and STI testing was self-administered at baseline and 12-month follow-up. Analyses compared the conditions in terms of their impact on the primary outcome - past-30-day HIV-transmission-risk behavior. Secondary outcomes included mental (e.g., depression symptoms) and behavioral health (e.g., alcohol use) measures. We also examined between-condition change in hypothesized IMB and minority stress mechanisms. The conditions did not significantly differ in any primary or secondary outcomes over time. Both conditions demonstrated decreases in past-30-day HIV-transmission-risk behavior, number of heavy drinking days, depression and anxiety symptoms, and suicidal ideation over the 12-month follow-up period. Education control participants reported significantly greater increases in alcohol- and HIV/AIDS-related knowledge, while Comunica participants reported significantly greater decreases in perceived benefits of condomless sex across the follow-up period. Both conditions showed improvements in self-efficacy for condom use and alcohol use reduction and in all minority stress factors across the follow-up period. As all participants reported similar improvements across outcomes, future research is needed to determine how to best support this stigmatized population's health given the limited population-specific supports.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148757929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implications of Disruptions in HIV-Related Metrics.","authors":"David R Holtgrave, Ronald O Valdiserri","doi":"10.1007/s10461-026-05260-w","DOIUrl":"https://doi.org/10.1007/s10461-026-05260-w","url":null,"abstract":"<p><p>Rigorous and timely HIV-related surveillance is essential to monitoring progress toward national, state, and local programmatic goals, making midcourse corrections, and informing policymaking. Decades of work have gone into making HIV surveillance a leading example in public health measurement systems. However, some disruption of, and uncertainty about this key surveillance system has begun. Here, we described the uncertainty regarding the National HIV Behavioral Surveillance (NHBS) system, estimation of HIV incidence, and tracking of HIV-related health disparities. Further, we articulate potential disruptive impact on the field and make recommendations so as to rectify these challenges to the HIV surveillance data systems before further harm is done. While it is still possible to end the HIV epidemic by 2030 in the United States, a strong, rigorous, comprehensive and timely measurement system for key metrics is a necessity.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants and Strategies for Implementation of an Adapted Data to Care Vertical HIV Prevention Intervention in a South African Context.","authors":"Yolanda Gomba, Lucia Knight, Landon Myer, Tamsin-K Phillips","doi":"10.1007/s10461-026-05272-6","DOIUrl":"10.1007/s10461-026-05272-6","url":null,"abstract":"<p><p>Despite progress in preventing new HIV infections in children, retention in vertical transmission prevention (VTP) remains a challenge in low-resource settings. The REMInD intervention used an adapted Data to Care (D2C) approach with tracing to support mother-infant pairs in completing VTP care. This qualitative study aimed to explore the potential implementation determinants and strategies to enhance the successful implementation of the REMInD intervention in Gugulethu, South Africa. Interviews were conducted with nurses, policy implementers, and mothers who had participated in the REMInD proof-of-concept study. We applied the Consolidated Framework for Implementation Research (CFIR) to identify determinants that could influence future implementation. Data were analysed using inductive thematic analysis. Key potential implementation determinants were identified across multiple CFIR domains. Within the Inner setting domain, limited availability of human resources and infrastructure posed key barriers. Under the Individual domain, the capability to retrieve and use data reports was a central concern. The Innovation domain was reflected in the perceived complexity of data retrieval and tracing procedures, particularly in informal settlements with poor infrastructure. Finally, in the Outer setting domain, HIV-related stigma emerged as a potential barrier. To address these challenges, several strategies were proposed by participants: (i) train and give access to the intervention for all nurses to mitigate staffing shortages, (ii) partnerships with NGOs to enhance patient tracing and support service delivery, (iii) collaboration within the health system to sustain support and resource availability, and (iv) dedicated champions to drive implementation. These findings highlight intersecting systemic, contextual, and individual factors influencing REMInD and similar D2C implementation. Strategies addressing staffing, infrastructure, and tracing gaps could enhance implementation success and HIV retention in low-resource settings.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148719993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual Behaviour, HIV Prevention and Testing Among Transgender and Non-binary People in a Cross-Sectional Behavioural Surveillance Survey in Aotearoa New Zealand.","authors":"Peter J W Saxton, Ryan M Bentham, Brooke M Hollingshead, Jack Byrne, Ashe Yee, Janine Paynter, Koson Tony Sriamporn","doi":"10.1007/s10461-026-05279-z","DOIUrl":"https://doi.org/10.1007/s10461-026-05279-z","url":null,"abstract":"<p><p>Trans and non-binary (TNB) people who have sex with gay, bisexual and other men who have sex with men (GBM) are rarely included in HIV behavioural surveillance. Improved data on risk and protective behaviours among TNB people could help identify unmet needs. We analysed data from the Sex and Prevention of Transmission Study, a cross-sectional HIV behavioural surveillance programme in Aotearoa New Zealand that extended eligibility to TNB participants for the first time in 2022. We categorised TNB participants who reported sex with GBM < 5 years into four groups: trans women (TW), trans men (TM), non-binary people assigned male at birth (AMAB), non-binary people assigned female at birth (AFAB). TNB participants were younger, more socioeconomically disadvantaged, and reported more long‑term disability than cis GBM. Compared to cis GBM, TM and non-binary AFAB participants reported fewer male partners and more sex with women and non‑binary partners, whereas TW and non-binary AMAB participants' partnering more closely resembled cis GBM. HIV testing < 12 months was lower across all TNB groups, and PrEP < 6 months was lower among TM and non-binary AFAB participants. Sexually transmitted infection screening and diagnosis < 12 months appeared similar across all participants; few TNB participants reported living with HIV. TNB participants reported higher levels of negative healthcare experiences and injecting drug use, but not methamphetamine use. Each TNB subpopulation had a unique behavioural profile that differed from both other TNB participants and cis GBM. Lower uptake of HIV testing and PrEP could reflect less risk exposure, service barriers, or both.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Motivation but Low Access to PrEP: Social Determinants Undermine HIV Prevention Among Sexual and Gender Minority People Who Use Methamphetamine.","authors":"Christian Grov, Alexa B D'Angelo, Chloe Mirzayi, Michell Dearolf, Elena Hoeppner, Yan Guo, Nicole Richards, Rifa Ehsan, Denis Nash, Viraj V Patel, Dustin T Duncan, Meredith Ray, Tyler Bartholomew, Jennifer A Manuzak, Jennifer K Manuel, Kathryn McCollister, Drew Westmoreland, Adam W Carrico","doi":"10.1007/s10461-026-05265-5","DOIUrl":"10.1007/s10461-026-05265-5","url":null,"abstract":"<p><p>Methamphetamine (meth) use is endemic among sexual and gender minority (SGM) populations and a well-established correlate of HIV acquisition. Less understood are the behavioral, psychosocial, and structural vulnerabilities associated with meth use that may complicate HIV prevention. We examined differences in HIV-related vulnerabilities, perceptions of pre-exposure prophylaxis (PrEP) need, and access to PrEP care among SGM people who use meth compared with those who do not. Cross-sectional data were drawn from the baseline assessment (2022-2023) of a U.S. national cohort of SGM individuals aged 16-49 (n = 2,847 who used meth; n = 2,518 who did not). Participants completed an online survey assessing demographics, vulnerabilities associated with HIV acquisition and barriers to PrEP access, and PrEP use and interest. Multivariable logistic regression compared participants who recently used meth with those who did not. Compared with non-users, participants who used meth reported greater HIV-related vulnerability across multiple domains, including higher behavioral risk, greater socioeconomic disadvantage, lower engagement in HIV testing, and poorer psychosocial and mental health outcomes. They were also more likely to perceive themselves as appropriate candidates for PrEP and express interest in initiating PrEP, yet less likely to report access to resources and infrastructure that facilitate engagement in PrEP care. These findings may reflect a phenomenon we term the \"Meth-PrEP Paradox,\" whereby individuals who use meth recognize their heightened vulnerability to HIV and express interest in PrEP while simultaneously encountering barriers to PrEP care. Longitudinal research is needed to evaluate this framework and identify strategies to improve HIV prevention among SGM people who use meth.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uptake of HIV Retesting Among Black Populations in Miami-Dade: Implications for Community-Based Prevention.","authors":"BreAnne Young, Olveen Carrasquillo, Yue Pan, Deborah L Jones, Sonjia Kenya","doi":"10.1007/s10461-026-05273-5","DOIUrl":"https://doi.org/10.1007/s10461-026-05273-5","url":null,"abstract":"<p><p>The Southern United States bears nearly half of all new HIV diagnoses, with Miami-Dade County experiencing one of the highest incidence rates nationwide. Black communities in Miami face disproportionate HIV-related outcomes, yet little is known about repeat HIV testing within these populations. This study examined engagement in HIV retesting through the Community-Based HIV Awareness for Minority Populations (CHAMP) program, a community health worker-led, street-based HIV testing and linkage-to-care initiative serving historically Black communities in Miami-Dade County. From December 2016 to February 2020, participants received rapid HIV testing and completed surveys assessing demographic characteristics and behavioral risk factors. Univariable analyses and latent class analysis were used to examine factors associated with CHW-facilitated retesting, defined as completing more than one HIV test through CHAMP. Among 1825 participants, 51% were female, 91% identified as Black, and the median age was 38 years. Approximately half reported at least one HIV-related risk behavior. Although 77% had previously tested for HIV, only 6% (n = 98) completed repeat testing through CHAMP. Retesting differed significantly by ethnicity and nativity but was not associated with latent class membership. Despite substantial baseline HIV risk, repeat testing within this CHW-led program remained low, with meaningful variation across cultural subgroups. Culturally tailored strategies that emphasize the importance of routine retesting may strengthen sustained engagement in HIV prevention services among high-priority populations.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148697021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence and Early Indicators of HBV and HCV Co-infection Among Newly Diagnosed HIV Patients: A Cross-Sectional Study from India.","authors":"Nawaid Hussain Khan, Shashi Nandar Kumar, Vishwajeet Singh, Gaurav Kaushik, Hafiz Ahmad, Raj Narayan Yadav, Richa Vashishtha, Rohit Kumar Tiwari, Ankush Kumar Rana, Vinay Kumar, Chaitenya Verma","doi":"10.1007/s10461-026-05251-x","DOIUrl":"https://doi.org/10.1007/s10461-026-05251-x","url":null,"abstract":"<p><p>HIV-HBV and HIV-HCV co-infections contribute significantly to liver-associated morbidity and mortality among people living with HIV (HIV/AIDS). Detection of these hepatitis co-infections at the time of HIV diagnosis is critical for the selection of the most suitable HAART regimen to improve long-term health outcomes. A cross-sectional study was conducted among 282 newly diagnosed, HIV-1 adult patients and screened for HBV (HBsAg) and HCV (anti-HCV) using immunoassays. Sociodemographic, behavioral, hematological, biochemical, immunological, and virological parameters were analyzed. Multinomial logistic regression was used to determine relative risk ratios (RRR) for co-infections. Among all participants HIV-HBV and HIV-HCV co-infections had 3.9% and 2.5% seroprevalence respectively. Previous or present injection drug use was the best predictor, with RRR = 74.86 (95% CI 11.7-478.9, p < 0.001) for HIV-HBV and RRR = 174.67 (95% CI 22.6-1348.1, p < 0.001) for HIV-HC Non-heterosexual HIV transmission modes were also significant predictors (RRR = 8.30, 95% CI 2.2-31.2, p = 0.002 for HIV-HBV; RRR = 10.9, 2.3-52.7, HCV, p = 0.003). Compared to HIV-only patients, co-infected patients had significantly elevated bilirubin, SGOT, SGPT, and ALP levels, lower platelet counts and serum albumin, higher ESR, and higher HIV viral loads. Furthermore, sexual orientation (< 0.001) and substance abuse (< 0.001) significantly contribute to health risk behaviors. These findings highlights the prevalence of HBV and HCV co-infection among newly diagnosed HIV patients is lower than the global prevalence among HIV/AIDS. However, the baseline laboratory abnormalities and high-risk behaviors may serve as early indicators of co-infection, supporting routine hepatitis screening in newly diagnosed HIV patients.</p>","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148697014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}