AIDS and Behavior最新文献_第4页

Participant-reported Outcomes from the CAPELLA Clinical Trial of Lenacapavir-based Regimens in Heavily Treatment-experienced Adults with HIV.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-10 DOI: 10.1007/s10461-025-04625-x

Moti Ramgopal, Dylan J Mezzio, Keith Dunn, Shan-Yu Liu, Damemarie Paul, Martin S Rhee, Antonella Castagna

{"title":"Participant-reported Outcomes from the CAPELLA Clinical Trial of Lenacapavir-based Regimens in Heavily Treatment-experienced Adults with HIV.","authors":"Moti Ramgopal, Dylan J Mezzio, Keith Dunn, Shan-Yu Liu, Damemarie Paul, Martin S Rhee, Antonella Castagna","doi":"10.1007/s10461-025-04625-x","DOIUrl":"https://doi.org/10.1007/s10461-025-04625-x","url":null,"abstract":"Lenacapavir, a first-in-class inhibitor of HIV-1 capsid function, can be administered twice yearly subcutaneously (SC). In the ongoing Phase 2/3 CAPELLA study (NCT04150068), the addition of SC lenacapavir to an optimized background regimen led to high rates of virologic suppression and was generally well tolerated. We describe participant-reported, health-related quality-of-life (HRQoL) outcomes with lenacapavir among heavily treatment-experienced people with HIV (PWH) from CAPELLA. Scores from EQ-5D-5L index and visual analogue scale (VAS), Short Form 36 (SF-36), HIV-Symptom Index (HIV-SI), and Numeric Pain Rating Scale (NPRS) at injection were collected. Mean baseline and week (W) 52 scores were: EQ-5D-5L index, 0.87 and 0.83; EQ-5D-5L VAS, 81 and 86; SF-36 physical component, 48.5 and 49.9; SF-36 mental component, 48.4 and 48.0. Scores remained stable over time (< 7% change), with values near US norms. For 15 of 20 HIV-SI symptoms, fewer participants reported them as bothersome at W52 than at baseline. Mean NPRS scores on injection were 3.9, 5.1, and 4.4 at first (W0), second (W26), and third injection (W52). Participants on lenacapavir-based regimens demonstrated stability or improvement in HRQoL and other outcomes, with fewer participants reporting bothersome HIV symptoms. These data can help clinicians address individuals' needs and medication preferences while achieving sustained virologic suppression in heavily treatment-experienced PWH.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mapping Vaccination Mindsets among UK Residents of Black Ethnicities with HIV: Lessons from COVID-19.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-10 DOI: 10.1007/s10461-025-04622-0

Zoe Moon, Lucy Campbell, Zoe Ottaway, Julie Fox, Fiona Burns, Lisa Hamzah, Andrew Ustianowski, Amanda Clarke, Sarah Schoeman, Deirdre Sally, Shema Tariq, Frank A Post, Rob Horne

{"title":"Mapping Vaccination Mindsets among UK Residents of Black Ethnicities with HIV: Lessons from COVID-19.","authors":"Zoe Moon, Lucy Campbell, Zoe Ottaway, Julie Fox, Fiona Burns, Lisa Hamzah, Andrew Ustianowski, Amanda Clarke, Sarah Schoeman, Deirdre Sally, Shema Tariq, Frank A Post, Rob Horne","doi":"10.1007/s10461-025-04622-0","DOIUrl":"https://doi.org/10.1007/s10461-025-04622-0","url":null,"abstract":"Vaccine hesitancy is a leading threat to public health, but little is known about the beliefs and mindsets that drive vaccine hesitancy, especially among people of Black ethnicities. This study aimed to understand vaccine related beliefs and their relationship with SARS-CoV-2 vaccine uptake in UK residents of Black ethnicities living with HIV. Adults of self-reported Black ethnicities with HIV were recruited at 12 clinics in England. Participants completed questionnaires in clinic, including an adapted version of the Beliefs about Medicines Questionnaire (BMQ) to assess Necessity and Concerns beliefs about the SARS-CoV-2 vaccine. SARS-CoV-2 vaccination status was ascertained through self-report and shared care records. A total of 863 participants were enrolled between June 2021 and October 2022, most of whom (92%) had received at least one dose of the SARS CoV-2 vaccine. After adjusting for age and region of birth, higher perceived need for the vaccine (OR = 2.39, 95% CI = 1.51-3.81), fewer concerns about the vaccine (OR = 0.16, 95% CI = 0.08-0.30), and weaker endorsement of COVID-19 Conspiracy Beliefs (OR = 0.31, 95% CI = 0.19-0.50) were associated with vaccination uptake. Being born outside sub-Saharan Africa was associated with reduced odds of being vaccinated. This study shows the importance of specific beliefs driving vaccine hesitancy and uptake. Further studies should explore the role of these beliefs and mindsets in influencing uptake of other vaccinations, and to work with key stakeholders to explore how to address vaccine hesitancy and improve vaccine uptake in these and other populations.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experiences, Attitudes and Preferences of Postpartum Cisgender Women for HIV Prevention and Pre-Exposure Prophylaxis Education during Routine Postpartum Care.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-10 DOI: 10.1007/s10461-025-04663-5

Caroline E Mullis, Jessica McWalters, Alison J Goldberg, Aloke Maity, Karina Avila, Sarit A Golub, Marla J Keller

{"title":"Experiences, Attitudes and Preferences of Postpartum Cisgender Women for HIV Prevention and Pre-Exposure Prophylaxis Education during Routine Postpartum Care.","authors":"Caroline E Mullis, Jessica McWalters, Alison J Goldberg, Aloke Maity, Karina Avila, Sarit A Golub, Marla J Keller","doi":"10.1007/s10461-025-04663-5","DOIUrl":"https://doi.org/10.1007/s10461-025-04663-5","url":null,"abstract":"The postpartum period presents an opportunity to deliver comprehensive sexual health education. Understanding preferences of postpartum cisgender women (CGW) towards integration of HIV prevention education into postpartum care is necessary to support acceptability, appropriateness, and feasibility. Postpartum CGW were recruited during their postpartum hospital stay in Bronx, NY. Participants completed a survey including two best-worst scaling exercises that elicited preferences for receiving HIV prevention information and PrEP messaging. Utility scores were estimated using a hierarchical Bayes multinomial logit model and mathematically transformed into a probability scale presented as preference scores (PS), with higher numbers representing greater preference. Among 259 participants, 53% had never heard of PrEP before. Receiving information from a doctor was most preferred (13.4, 95%CI 12.7-14.0) followed by receiving information about HIV prevention combined with taking care of their health after having a baby (11.6, 95% CI 10.9-12.3). Latent class analysis revealed three classes: participants with greater preference for high touch services (e.g., in-person visits, doctor providing information), integrated information (e.g., HIV prevention information given in combination with sexual or maternal health information) and high technology services (e.g., a mobile phone application, telehealth visit). Participants preferred PrEP messaging related to themes of effectiveness, motherhood, safety and autonomy. Latent class analysis of PrEP messaging revealed two classes: one with participants preferring messages related to motherhood and safety and another preferring messages related to control and autonomy. The heterogeneity in preferences for receiving information at the patient level suggests a need for patient-centered, differentiated service delivery to support maximum receptivity.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HPV Vaccine Uptake and its Predictors among Adolescent Girls and Young Women Living with HIV-in Central Uganda.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-10 DOI: 10.1007/s10461-025-04654-6

Anita Kabarambi, Samuel Kizito, Jean Hunleth, Michelle I Silver, Nixon Niyonzima, Fred Ssewamala

{"title":"HPV Vaccine Uptake and its Predictors among Adolescent Girls and Young Women Living with HIV-in Central Uganda.","authors":"Anita Kabarambi, Samuel Kizito, Jean Hunleth, Michelle I Silver, Nixon Niyonzima, Fred Ssewamala","doi":"10.1007/s10461-025-04654-6","DOIUrl":"https://doi.org/10.1007/s10461-025-04654-6","url":null,"abstract":"This study aimed to assess HPV vaccine uptake and its predictors among adolescent girls and young women living with HIV. We analyzed cross-sectional baseline data from a pilot randomized controlled trial involving 100 girls and young women (aged 10-24 years) living with HIV and receiving care in Uganda's Greater Masaka region. The study was conducted in four Antiretroviral(ART) providing healthcare facilities between January and March 2024. Surveys were used to collect data on socio-demographics (age, religion, education), HPV acceptability, barriers to vaccination, perceived susceptibility, knowledge about HPV and cervical cancer, and HPV vaccine uptake. We then conducted a logistic regression analysis to determine the predictors of HPV vaccine uptake. We also tested assumptions for the logic regression. The health belief model guided us in selecting the variables to include in the final logistic regression model. The findings revealed a low vaccine uptake rate, with only 31% vaccinated participants. Significant predictors included sexual experience (OR = 4.08, p = 0.011) and HPV knowledge (OR = 1.41, p = 0.016). Participants without sexual experience were four times more likely to be vaccinated, and higher HPV knowledge increased the likelihood of vaccination. However, perceived barriers, susceptibility, and cervical cancer knowledge were not significant predictors. These findings highlight the need to address barriers and improve HPV knowledge to enhance vaccine uptake, particularly among adolescent girls and young women living with HIV.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Impact of Body Mass Index and VO2 Max on Symptoms, Physical Activity, and Physical Function in a Multinational Sample of People With HIV

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-07 DOI: 10.1007/s10461-025-04666-2

Christine Horvat Davey, Deepesh Duwadi, J. Craig Phillips, Carol Dawson-Rose, Kathleen M. Nokes, Joseph Perazzo, Rebecca Schnall, Penny Orton, Mary Jane Hamilton, Rita Musanti, Kimberly Adams Tufts, Elizabeth Sefcik, Allison R. Webel

引用次数: 0

Patterns of Cannabis Use among Women With HIV in the United States.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-07 DOI: 10.1007/s10461-025-04669-z

Danielle F Haley, Brooke W Bullington, Phyllis Tien, Andrea K Knittel, Julie Bobitt, Mirjam-Colette Kempf, Morgan Philbin, David B Hanna, StarrLa'diamond Lindsey, Seble Kassaye, Jack DeHovitz, Mardge Cohen, Gina Wingood, Deborah L Jones, Michael P Williams, Richard J Wang, Andrew Edmonds

{"title":"Patterns of Cannabis Use among Women With HIV in the United States.","authors":"Danielle F Haley, Brooke W Bullington, Phyllis Tien, Andrea K Knittel, Julie Bobitt, Mirjam-Colette Kempf, Morgan Philbin, David B Hanna, StarrLa'diamond Lindsey, Seble Kassaye, Jack DeHovitz, Mardge Cohen, Gina Wingood, Deborah L Jones, Michael P Williams, Richard J Wang, Andrew Edmonds","doi":"10.1007/s10461-025-04669-z","DOIUrl":"https://doi.org/10.1007/s10461-025-04669-z","url":null,"abstract":"Cannabis legalization in the United States changed cannabis product potency and consumption modalities. Women with HIV are an aging population with prevalent cannabis use twice that of national estimates. Because cannabis use may confer both health benefits and risks, it is important to understand cannabis use patterns among women with HIV. This analysis characterized prevalence, frequencies, and modes (smoking, vaping, eating) of cannabis use among 1,246 women with HIV in the Women's Interagency HIV Study over 18 months (2018-2019). We compared participant characteristics using chi-square tests and Wilcoxon rank-sum tests. We illustrated flow between cannabis use frequency categories with a Sankey diagram. Median participant age was 52 years (interquartile range: 46, 58). 65% of participants identified as Black/African American; 50% had annual household incomes <$12,000. The period prevalence was 27% for any cannabis use and 15% for daily or more use. 50% reported varying use frequencies. Among women using cannabis, 96% reported smoking, 30% consumed edibles, and 18% vaped. Compared with women not using cannabis, greater proportions of women using cannabis reported alcohol (69% vs. 37%, p < 0.01), cigarette (61% vs. 29%, p < 0.01) and other drug use (16% vs. 4%, p < 0.01). Compared to those with no high potency use, a higher proportion of women using high potency products were in a state legalizing cannabis sales. Cannabis use among women with HIV is common and of variable frequency. Future work should characterize patterns of use, product choice motivations, and associated health impacts in the context of aging and HIV.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interventions and Strategies to Increase Cervical Cancer Screening, Treatment, and Retention in Care among Persons with HIV in Low- and Middle-Income Countries: A Systematic Review.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-07 DOI: 10.1007/s10461-025-04678-y

Riya Mittal, Katherine E Kabel, Madison R Fertig, Jane H Lee, Nzwakie Mosery, Jennifer N Githaiga, Jenni Smit, Christina Psaros, Amelia M Stanton

{"title":"Interventions and Strategies to Increase Cervical Cancer Screening, Treatment, and Retention in Care among Persons with HIV in Low- and Middle-Income Countries: A Systematic Review.","authors":"Riya Mittal, Katherine E Kabel, Madison R Fertig, Jane H Lee, Nzwakie Mosery, Jennifer N Githaiga, Jenni Smit, Christina Psaros, Amelia M Stanton","doi":"10.1007/s10461-025-04678-y","DOIUrl":"https://doi.org/10.1007/s10461-025-04678-y","url":null,"abstract":"Cervical cancer (CC) and HIV pose two major public health challenges, with low and middle-income countries (LMICs) exhibiting the highest disease burden and mortality rate for both HIV and CC-related deaths worldwide. Populations with HIV in LMICs are six times more likely to develop CC compared to the general population. Further, CC is the most frequently detected cancer and leading cause of death among women with HIV (WWH). This systematic review synthesized the literature and identified key elements of interventions to increase CC awareness, screening, treatment, and retention in care among persons with HIV in LMICs. Four databases were searched for peer reviewed articles in the last 10 years that described and assessed the effectiveness of these interventions, and 10 articles were identified and reviewed. Interventions that included community/spiritual leaders, trained non-physician medical providers, used pre-existing facilities (e.g. HIV, family planning, reproductive health), integrated \"screen and treat\" approaches, and used visual inspection methods (VIA/VILI; excluding Pap smears) were associated with higher rates of CC awareness, screening, engagement in subsequent treatment, and overall retention in care. Most studies focused on increasing awareness, screening, and engagement in care, demonstrating the need for interventions that are also designed to increase retention in the CC continuum of care among WWH. Additionally, few interventions had long follow-up periods, which should be included to effectively track sustained retention in care.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Pandemic's Impact on HIV and AIDS Case Reporting in Peru: A Time Series Analysis of Surveillance Data (1983-2023).

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-03 DOI: 10.1007/s10461-025-04655-5

Yordanis Enríquez Canto

{"title":"COVID-19 Pandemic's Impact on HIV and AIDS Case Reporting in Peru: A Time Series Analysis of Surveillance Data (1983-2023).","authors":"Yordanis Enríquez Canto","doi":"10.1007/s10461-025-04655-5","DOIUrl":"https://doi.org/10.1007/s10461-025-04655-5","url":null,"abstract":"The COVID-19 pandemic substantially disrupted healthcare services worldwide, and its impact on the identification and reporting of HIV and AIDS cases has become a critical concern. This study evaluated the effects of the pandemic on HIV/AIDS surveillance in Peru through a natural experiment using interrupted time series analysis of national surveillance data. Analysis of trends from 1985 to 2023 for HIV and from 1983 to 2023 for AIDS revealed consistent pre-pandemic increases, with an average annual growth of 27.02% for HIV cases and 20.48% for AIDS cases. However, the onset of the pandemic in 2020 was associated with significant immediate declines, with reductions of 1,609.86 HIV cases (95% CI: -3,147.26 to - 72.46) and 1,187.68 AIDS cases (95% CI: -1,560.10 to - 815.26). Furthermore, comparisons against ARIMA forecasts (HIV accuracy = 84.80%, AIDS accuracy = 85.45%) indicated substantial underreporting during the 2020-2023 period-estimated at 15.77% for HIV and 29.03% for AIDS cases. These results underscore the adverse effect of the COVID-19 crisis on ongoing HIV/AIDS case detection and reporting in Peru. They also highlight the urgent need for robust strategies-such as expanding telemedicine, enhancing self-testing, and reinforcing community-based interventions-to ensure continuous access to diagnosis and treatment during public health emergencies.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive Psychological Factors Relate to Domain-Specific Cognition and Daily Functioning in Middle-Aged and Older Adults with HIV.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-03 DOI: 10.1007/s10461-025-04636-8

Lillian Ham, Maulika Kohli, Bin Tang, Igor Grant, David J Moore

{"title":"Positive Psychological Factors Relate to Domain-Specific Cognition and Daily Functioning in Middle-Aged and Older Adults with HIV.","authors":"Lillian Ham, Maulika Kohli, Bin Tang, Igor Grant, David J Moore","doi":"10.1007/s10461-025-04636-8","DOIUrl":"https://doi.org/10.1007/s10461-025-04636-8","url":null,"abstract":"Understanding positive psychological factors (PPFs; internal strengths, socioemotional support) that promote optimal health outcomes among people with HIV (PWH) is increasingly important. 122 PWH and 98 people without HIV (PWoH) were included in multivariable regressions, testing interactions between HIV status and PPFs on 7 cognitive domains and 2 daily functioning outcomes, controlling for depressive symptoms. Overall, higher internal strengths were related to better learning and memory, whereas higher socioemotional support was related to better processing speed and psychomotor speed. PWH had a stronger positive relationship between PPFs and verbal fluency than PWoH. Overall, higher internal strengths were associated with fewer daily functioning impairments; however, only PWoH showed fewer functional declines with higher socioemotional support. PWH may require greater socioemotional support to accommodate an increased burden of comorbidities leading to functional difficulties. Among PWH, bolstering PPFs may improve cognition; however, internal strengths may particularly benefit daily functioning.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Universal Approach to Educating Patients with HIV about Long-Acting Injectable Treatment for HIV.

IF 2.7 2区医学

AIDS and Behavior Pub Date : 2025-03-03 DOI: 10.1007/s10461-024-04610-w

Bijou Hunt, Alice Pham, Nancy Glick, Sharon Sam, Keyang Ni, Kathrine Meyers, Nadia Nguyen

{"title":"A Universal Approach to Educating Patients with HIV about Long-Acting Injectable Treatment for HIV.","authors":"Bijou Hunt, Alice Pham, Nancy Glick, Sharon Sam, Keyang Ni, Kathrine Meyers, Nadia Nguyen","doi":"10.1007/s10461-024-04610-w","DOIUrl":"https://doi.org/10.1007/s10461-024-04610-w","url":null,"abstract":"Long-acting injectable antiretroviral treatment (LAI ART) has the potential to transform HIV care and reduce HIV-related health inequities in achieving and maintaining viral suppression. However, without a plan for equitable roll-out of LAI ART, new pharmacological innovations in HIV treatment and prevention risk further deepening health disparities. This study delineates a process for providing universal LAI ART education to people with HIV (PWH) at an urban outpatient infectious disease clinic and documents the outcomes of these efforts. We compared the number and proportion of patients with HIV educated about injectable cabotegravir-rilpivirine (iCAB/RPV) and, among those educated, the number and proportion of patients interested in learning more about iCAB/RPV under a selective education model compared to a universal education model, disaggregated by race/ethnicity, sex, and age. We used a Chi-sq test to estimate p-values for the difference in proportions. The universal compared to selective education approach resulted in a larger proportion of clients educated and a greater proportion of people educated reporting interest in LAI ART. Slight differences observed between those never versus ever educated in the selective education were absent after the adoption of a universal education approach. Reasons for disinterest -- including fear of injections, not interested in more frequent clinic visits, and content with oral ART regimen -- did not differ across educational approaches. Our programmatic data offers preliminary evidence that a universal education approach can support and enhance equitable roll-out of LAI ART. Most patients with HIV are interested in learning more about LAI ART.","PeriodicalId":7543,"journal":{"name":"AIDS and Behavior","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0