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Acta pathologica et microbiologica Scandinavica. Section C, Immunology最新文献

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Effects of acetylsalicylic acid on lymphocyte subpopulations in peripheral blood. 乙酰水杨酸对外周血淋巴细胞亚群的影响。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-04-01
S F Sørensen, A Dirksen, J Jensenius, V Jønsson, P Platz, G S Hansen
{"title":"Effects of acetylsalicylic acid on lymphocyte subpopulations in peripheral blood.","authors":"S F Sørensen,&nbsp;A Dirksen,&nbsp;J Jensenius,&nbsp;V Jønsson,&nbsp;P Platz,&nbsp;G S Hansen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The in vitro and in vivo effects of therapeutical doses of acetylsalicylic acid on lymphocyte subpopulations in peripheral blood were investigated with the following results: Acetylsalicylic acid caused both in vitro and in vivo a reduction of complement receptor bearing lymphocytes and of lymphocytes identified with fluorescent rabbit antibody to human Ig (polyvalent) and to human IgG. Sheep red blood cell receptor bearing lymphocytes, and lymphocytes identified with antibody to human IgM and IgD were unaffected by acetylsalicylic acid.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 2","pages":"107-12"},"PeriodicalIF":0.0,"publicationDate":"1979-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11307837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A solid-phase, polyclonal IgM-RF binding assay for circulating immune complexes. 循环免疫复合物的固相多克隆IgM-RF结合试验。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-04-01
G Glikmann, S E Svehag, H Nielsen
{"title":"A solid-phase, polyclonal IgM-RF binding assay for circulating immune complexes.","authors":"G Glikmann,&nbsp;S E Svehag,&nbsp;H Nielsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A polyclonal IgM-RF-binding assay (pRF-BA) for the detection of circulating immune complexes (IC) is described. The method is based on the competitive binding of heat-treated iodinated IgG (deltaIgG) and naturally occurring IC to solid phase IgM-RF. The sensitivity limit of the assay was 300--400 ng deltaIgG/ml dilute serum. The coefficient of variation for the assay varied from 6 to 12% of the total binding when deltaIgG concentrations up to 1 microgram/ml were measured. One hundred and six patient sera were examined for IC occurrence and significant differences (p less than 0.01) were observed between 30 normal control sera and sera from SLE, sarcoidosis and glomerulonephritis patients. About 40% of patients suffering from acute myocardial infarction (AMI) gave IC-positive reactions with samples taken 5 to 10 days after the infarction. The kinetics of IC appearance was studied in AMI patients by the pRF-BA and three complement-dependent assays. IC appearance was registered in the RF assay 5 to 12 days after the rise in ASAT enzyme values and the IC reactivity corresponded to complexes ranging from 2 to 5 x 10(6) in molecular weight.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 2","pages":"121-9"},"PeriodicalIF":0.0,"publicationDate":"1979-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11328731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibody responses in urine and serum against Escherichia coli O antigen in childhood urinary tract infection. 儿童尿路感染中尿和血清对大肠杆菌O抗原的抗体反应。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
A S Akerlund, S Ahlstedt, L A Hanson, U Jodal
{"title":"Antibody responses in urine and serum against Escherichia coli O antigen in childhood urinary tract infection.","authors":"A S Akerlund,&nbsp;S Ahlstedt,&nbsp;L A Hanson,&nbsp;U Jodal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11581910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salmonella typhi--induced stimulation of blood lymphocytes from persons with previous typhoid fever. 伤寒沙门氏菌——引起既往伤寒患者血液淋巴细胞的刺激。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
H H Mogensen
{"title":"Salmonella typhi--induced stimulation of blood lymphocytes from persons with previous typhoid fever.","authors":"H H Mogensen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 21 persons with previous typhoid fever and in 15 controls thymidine incorporation of blood lymphocytes stimulated in vitro by killed Salmonella typhi was studied. The optimal culture conditions were established to be a cell density of 10(5) cells per vial, stimulated with 10(8) S. typhi and incubated for 5 days. The lymphocytes response to S. typhi was significantly higher in the typhoid group than in the controls. The lymphocyte responsiveness was not correlated to the time elapsed since the attack, and was not found different in patients who had had typhoid relapse. No difference was found in lymphocyte response to the mitogens PHA, PWM and Con-A between the typhoid group and the controls.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"41-5"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11639653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation by macrophages of lymphocyte responses to phytohaemagglutinin, concanavalin A and semiallogeneic cells. 巨噬细胞调节淋巴细胞对植物血凝素、豆豆蛋白A和半异体细胞的反应。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
E Hem
{"title":"Modulation by macrophages of lymphocyte responses to phytohaemagglutinin, concanavalin A and semiallogeneic cells.","authors":"E Hem","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To investigate the effect of macrophages on rat lymphocyte activation by phytohaemagglutinin (PHA), concanavalin A (Con A) and semiallogeneic cells (uniderectional MLR), increasing concentrations of peritoneal cells (PC) were added to cultures of lymph node lymphocytes. Lymph node cell preparations contained 2-4% esterase positive cells (macrophages/monocytes). Any additional PC seemed only to inhibit MLR, whereas optimal responses of PHA and Con A stimulated cultures occurred when 1-2% abd 3-7% PC respectively were added. Ten percent PC markedly inhibited the response of both PHA and Con A stimulated cultures when added for the last 24 h of incubation. Inhibitory cells were shown to belong to the glass-wool adherent population of PC.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"17-21"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11639651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complement receptors in human peripheral nerve tissue. 人周围神经组织中的补体受体。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
H Nyland, R Matre, O Tönder
{"title":"Complement receptors in human peripheral nerve tissue.","authors":"H Nyland,&nbsp;R Matre,&nbsp;O Tönder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cryostat sections of human peripheral nerve tissue adsorbed sheep erythrocytes sensitized with antibody and human complement (EAC). Activated complement was essential for the reaction to occur. The receptor had specificity for the C3b fragment. In order to obrain binding to nerve tissue, the indicator cells had to be coated with more complement than that required for binding to C3b receptors in spleen and renal tissue. The receptors are located within the nerve fascicles and are probably of glycoprotein nature. The receptors for C3b in peripheral nerve tissus may be of significance in the deposition of immune complexes, which may play a role in acute polyradiculoneuritis.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"7-10"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11581743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and titres of smooth-muscle antibodies in human sera. 人血清中平滑肌抗体的发生率和滴度。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
P Andersen
{"title":"Incidence and titres of smooth-muscle antibodies in human sera.","authors":"P Andersen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By means of the indirect immunofluorescence method smooth-muscle antibodies (SMA) were determined in 182 patients with various diseases and the findings were compared with those of 7 patients with chronic active hepatitis (CAH) and 580 normal controls. IgG-SMA were found in 85.7% of the patients with CAH, titres above 80 occurred only in Hepatitis B-associated antigen (HBAg)-negative CAH, but IgG-SMA in low titres were also found with increased incidence in syphilis (16.7%) and in infections of the central nervous system (19%). In other diseases (Sjøgren's syndrome, ulcerative colitis, regional enteritis, myasthenia gravis, progressive muscular dystrophy, atopic dermatitis and mycoplasma pneumoniae infection) the prevalence did not differ from that of controls (3.6%). IgM-SMA were found more often in CAH (28.6%), in infections of the central nervous system (14.3%) and in the mycoplasma pneumoniae infections (13%) than in controls (2.6%), but titres above 20 occurred only in controls. IgA-SMA were detected only in a patient with syphilis. Demonstration of IgG-SMA titres above 80 seems to support the diagnosis of HBAg-negative CAH, while the demonstration of IgA- and IgM-SMA seems to be without diagnostic value in chronic hepatitis.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"11-6"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11581909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitation of Clr-Cls-Cl inactivator complexes by electroimmunoassay. 电免疫法定量Clr-Cls-Cl灭活剂复合物。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
A B Laurell, U Mårtensson, A G Sjöholm
{"title":"Quantitation of Clr-Cls-Cl inactivator complexes by electroimmunoassay.","authors":"A B Laurell,&nbsp;U Mårtensson,&nbsp;A G Sjöholm","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"79-81"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11639522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Activated complement in the sputum from patients with cystic fibrosis. 囊性纤维化患者痰中的活化补体。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
P O Schiøtz, H Sørensen, M Høiby
{"title":"Activated complement in the sputum from patients with cystic fibrosis.","authors":"P O Schiøtz,&nbsp;H Sørensen,&nbsp;M Høiby","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>14 cystic fibrosis (CF) patients chronically infected with mucoid P. aeruginosa and presenting multiple precipitins in serum against this bacterium (CF + P) and 13 CF patients without P. aeruginosa infection (CF-P) had their plasma and sputum sol phase examined for albumin, Clq. C3/C3c, C4 and C5 by means of electroimmunoassays. Their sputum sol phase was examined also for factor B by rocketimmunoelectrophoresis. C3c was demonstrated in the sputum sol phase but significantly more frequent (p less than 0.01) among the CF + P patients than among the CF-P patients. Factor B was also demonstrated in the sputum sol phase, but no significant difference in frequency could be demonstrated between the CF + P and the CF-P patients. None of the results indicated that a local pulmonary production of complement factors took place. Complement activation was significantly (p less than 0.01) associated with inflammation expressed as increased (formula: see text). The results show the importance of complement mediated inflammation in the pathogenesis of pulmonary tissue damage in patients with CF and support the concept of chronic P. aeruginosa lung infection as an immune complex disease in CF patients.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11639650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of mycoplasmas on phagocytosis and immunocompetence in rats. 支原体对大鼠吞噬能力和免疫能力的影响。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1979-02-01
A C Thomsen, I Heron
{"title":"Effect of mycoplasmas on phagocytosis and immunocompetence in rats.","authors":"A C Thomsen,&nbsp;I Heron","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to evaluate some possible mechanisms by which mycoplasmas may facilitate a subsequent bacterial infection. The effector of M. arthritidis, M. hominis and U. urealyticum on lymphocyte reactivity to mitogens, subsequent antibody response, and the ability of neutrophils to carry out phagocytosis was investigated. In vitro, large doses of M. arthritidis and M. hominis depressed the reactivity of lymphocytes and the phagocytic ability of neutrophils. In vivo, inoculation of myoplasmas had no effect on reactivity of lymphocytes from rats, and antibody response to subsequently injected E. coli was normal. However, peritoneal neutrophils from rats injected intraperitoneally with large doses of M. arthritidis and M. Hominis were invalidated in their ability to cause phagocytosis of E. Coli. U. urealyticum had no observable effect on lymphocytes and neutrophils in vitro and in vivo.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"87C 1","pages":"67-71"},"PeriodicalIF":0.0,"publicationDate":"1979-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11581911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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