Acta pathologica et microbiologica Scandinavica. Section C, Immunology最新文献

A MONOCLONAL IgM WITH SPECIFIC ANTIBODY REACTIVITY AGAINST KLEBSIELLA SERO‐TYPES 12 AND 13 一种对克雷伯氏菌血清型12和13具有特异性抗体反应性的单克隆IgM

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1975.TB01614.X

J. Eriksen, M. Harboe, Johanna Deverili

引用次数: 2

CAPSULAR SWELLING AND PASSIVE HAEMAGGLUTINATION INDUCED BY MONOCLONAL IgM REACTING WITH ACID POLYSACCHARIDES OF KLEBSIELLA 单克隆IgM与克雷伯菌酸性多糖反应诱导荚膜肿胀和被动血凝

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1975.TB01613.X

M. Harboe, J. Deverill, J. Eriksen

引用次数: 2

Immunological memory after priming with a thymus independent antigen, NIP-ficoll. 4-hydroxy-5-iodo-3-nitrophenylacetyl coupled to polymer of sucrose and epichlorhydrin. 胸腺非依赖性抗原(NIP-ficoll)启动后的免疫记忆。4-羟基-5-碘-3-硝基苯乙酰偶联蔗糖和环氧氯丙烷聚合物。

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1976.TB00041.X

M. Hurme

{"title":"Immunological memory after priming with a thymus independent antigen, NIP-ficoll. 4-hydroxy-5-iodo-3-nitrophenylacetyl coupled to polymer of sucrose and epichlorhydrin.","authors":"M. Hurme","doi":"10.1111/J.1699-0463.1976.TB00041.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00041.X","url":null,"abstract":"The capacity of mouse spleen fragments to mount an anti-NIP (4-hydroxy-5-iodo-3-nitrophenylacetyl) response in vitro was studied. The fragments came from unprimed, NIP-Ficoll (polymer of sucrose and epichlorhydrin) or NIP-CG (chicken globulin) primed mice. Unprimed spleen fragments from C57BL/6 mice gave a good anti-NIP response to NIP-Ficoll, whereas CBA fragments did not. Priming with NIP-Ficoll made CBA fragments responsive and enhanced slightly the response of C57BL/6 fragments when stimulated with the same antigen. This memory effect could be seen only after a small priming dose. Priming the mice with NIP-Ficoll made their spleen fragments responsive to a protein conjugate of NIP (NIP-CG), but this effect was seen only after priming with a high dose. The antibody class distribution and the kinetics of the appearance of different immunoglobulin classes were similar in the primary and secondary responses in vitro. The peak responses of IgM, IgA and IgG were reached on day eight and the relative amount of IgG was the same in the primary and in the secondary responses. Spleen fragments derived from NIP-CG primed mice produced more IgG anti-NIP antibodies than fragments derived from untreated mice when immunized in vitro with NIP-Ficoll. The amount of IgG was, however, much higher when these fragments were challenged with the homologous antigen, NIP-CG.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"56 1","pages":"345-52"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77627908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Lymphocyte subpopulations in Crohn's disease and chronic ulcerative colitis. 克罗恩病和慢性溃疡性结肠炎的淋巴细胞亚群

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1977.TB03609.X

S. Sørensen, L. Høj

引用次数: 8

OCCURRENCE OF HEPATITIS B SURFACE ANTIGEN (HBs Ag) IN BLOOD DONORS AND PATIENTS SUFFERING FROM TRANSFUSION HEPATITIS 乙型肝炎表面抗原(HBs Ag)在献血者和输血型肝炎患者中的发生率

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1975.TB01615.X

B. Hansson, G. Sundstrom, T. Johnsson

引用次数: 0

Experimental Escherichia coli 06 infection in mice. III. Effects of malnutrition, immunization and nutritional restoration. 实验性小鼠大肠杆菌06感染。3营养不良、免疫和营养恢复的影响。

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1981.TB02659.X

S. Ahlstedt

{"title":"Experimental Escherichia coli 06 infection in mice. III. Effects of malnutrition, immunization and nutritional restoration.","authors":"S. Ahlstedt","doi":"10.1111/J.1699-0463.1981.TB02659.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1981.TB02659.X","url":null,"abstract":"Inbred mice of the CBA and A strains were from weaning malnourished on a low protein diet. During a three-week period their weight increased from about 8 to about 10 g, while mice on normal feeding increased to about 16 g. This malnutrition resulted in a 10-fold increase of the susceptibility to intraperitoneally injected E. coli 06:K2a,2c:H1 bacteria compared to conventionally fed controls. Immunization as well as transfer of fresh immune serum to malnourished or normally-fed mice resulted in an increase in resistance, 6 to 10 fold that of non-immunized controls, while transfer of normal serum did not have a great impact on the resistance. Antibody titers to El coli 06 antigen in mice on poor and normal feeding were similar, as were there non-specific cellular responsiveness measured as lymphoblast transformation by ConA, PHA and LPS. The effect of the malnutrition seemed to be an impairment of the clearance of live E. coli 06 bacteria 1 h after a sub-lethal infection compared with that of normally-fed controls. The noted increased susceptibility to injections in the malnourished mice was rapidly restored by normal feeding for one day.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"100 1","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73733162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Antibiotics and granulocytes. Direct and indirect effects on granulocyte chemotaxis. 抗生素和粒细胞。对粒细胞趋化性的直接和间接影响。

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1981.TB02690.X

J. Belsheim, G. H. Gnarpe

引用次数: 12

The serology of Pseudomonas aeruginosa analysed by means of quantitative immunoelectrophoretic methods. 采用定量免疫电泳方法对铜绿假单胞菌进行血清学分析。

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1976.TB00044.X

N. Høiby

{"title":"The serology of Pseudomonas aeruginosa analysed by means of quantitative immunoelectrophoretic methods.","authors":"N. Høiby","doi":"10.1111/J.1699-0463.1976.TB00044.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00044.X","url":null,"abstract":"The conformity of the immunoprecipitate pattern obtained with a polyvalent Pseudomonas aeruginosa antigen (St-Ag) and different pools of a polyvalent, purified (IgG and IgA) rabbit antiserum (St-Ab) against St-Ag has been studied. Ten rabbits were immunized and bled every fifth week. Eight pools of St-Ab were produced during nearly four years. All the St-Ab pools were mutually compared by means of quantitative immuno-electrophoretic methods. All St-Ab pools were found to present St-Ag/St-Ab immunoprecipitate patterns which, qualitatively and quantitatively, were similar. None of the obtained immunoprecipitates between St-Ag and the pooled antisera disappeared during the procedures of purification of IgG and IgA. Quantitative and qualitative comparison of the polyvalent St-Ab pools (\"titre\") was made by counting the total number of immunoprecipitates obtained by St-Ag, followed by their identification, and by calculating the mean area of 12 selected and representative immunoprecipitate. The abilities of the rabbits to produce antibodies were found to vary individually. None of the rabbits produced precipitating antibodies against all the 64 known P. aeruginosa antigens in St-Ag. On the average, each of the rabbits lacked precipitating antibodies against 5 of the antigens. By pooling antisera from 3 rabbits out of 8 only 14 per cent of the possible combinations would contain detectable precipitins against all the known antigens of St-Ag.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"07 1","pages":"372-82"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85965789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Serotype determinant protein of Neisseria Meningitidis. Large scale preparation by direct detergent treatment of the bacterial cells. 脑膜炎奈瑟菌血清型决定蛋白。用直接去污剂处理细菌细胞的大规模制备。

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1981.TB02667.X

T. Helting, G. Guthöhrlein, F. Blackkolb, H. Ronneberger

{"title":"Serotype determinant protein of Neisseria Meningitidis. Large scale preparation by direct detergent treatment of the bacterial cells.","authors":"T. Helting, G. Guthöhrlein, F. Blackkolb, H. Ronneberger","doi":"10.1111/J.1699-0463.1981.TB02667.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1981.TB02667.X","url":null,"abstract":"Neisseria meningitidis Group B microorganisms, inactivated with phenol and harvested by centrifugation, were subjected to direct treatment with various detergents to solubilize the serotype determinant proteins localized in the outer membrane. Analysis of the data showed that extraction of the cells with detergents provided yields of the serotype protein substantially exceeding those obtained by simple salt extraction of the bacteria. Routinely, more than 2 mg of end product per g of cell mass (wet weight) may be recovered by the present method. By gel chromatographic analysis, the serotype determinant protein was shown to interact with the capsular polysaccharides derived from Group A or C Neisseria meningitidis microorganisms, forming high molecular weight complexes. This interaction markedly enhanced the solubility of the serotype determinant protein. Combined vaccines of the type-specific protein with the group- specific polysaccharides were evaluated for their immunogenic potential in the subcutaneous steel spring implant model. In guinea pigs, amounts corresponding to 10 micrograms completely prevented infection upon challenge with homologous organisms four weeks after immunization. Partial protection was observed with immunizing doses corresponding to 2 micrograms or 0.4 micrograms/animal, respectively. Compared to lyophilized preparations, vaccines adsorbed to a mineral carrier were slightly less effective in inducing protection, whereas inclusion of Bordetella pertussis as a component of the vaccine stimulated the immune response.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"19 1","pages":"69-78"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72994683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Pseudomonas aeruginosa infection in cystic fibrosis. Relative prevalence of antibodies in serum against cathodic and anodic migrating P. aeruginosa antigens determined by immunoelectrophoretic methods. 囊性纤维化中的铜绿假单胞菌感染。用免疫电泳法测定血清中抗阴极和阳极迁移铜绿假单胞菌抗原抗体的相对流行率。

Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1977.TB03624.X

Niels HØiby

引用次数: 5