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Acta pathologica et microbiologica Scandinavica. Section C, Immunology最新文献

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Pseudomonas aeruginosa infection in cystic fibrosis. Bactericidal effect of serum from normal individuals and patients with cystic fibrosis on P. aeruginosa strains from patients with cystic fibrosis or other diseases. 囊性纤维化中的铜绿假单胞菌感染。正常人和囊性纤维化患者血清对囊性纤维化或其他疾病患者血清中铜绿假单胞菌的杀菌作用
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1977.TB03619.X
Niels HØiby, S. Olling
{"title":"Pseudomonas aeruginosa infection in cystic fibrosis. Bactericidal effect of serum from normal individuals and patients with cystic fibrosis on P. aeruginosa strains from patients with cystic fibrosis or other diseases.","authors":"Niels HØiby, S. Olling","doi":"10.1111/J.1699-0463.1977.TB03619.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB03619.X","url":null,"abstract":"P. aeruginosa strains originating from the respiratory tract of patients with cystic fibrosis (CF) and patients with other diseases (non-CF) were analysed with regard to their sensitivity to the bactericidal activity of human serum. P. aeruginosa strains isolated from CF patients were more sensitive than strains from non-CF patients to the bactericidal activity of normal human serum. The bactericidal activity was heatlabile. As regards the sensitivity to normal human serum, mucoid and non-mucoid variants were not found to differ. Strains originating from chronically infected CF patients with many precipitins against these bacteria did not differ with respect to serum sensitivity from strains originating from intermittently colonized CF patients without P. aeruginosa precipitins. Compared with normal sera, CF sera showed similar or higher bactericidal activity against a panel of P. aeruginosa strains. In this respect, any difference between CF sera with precipitins and CF sera without precipitins against P. aeurginosa was not found. Sera from three CF patients chronically infected with P. aeruginosa, and with many precipitins against these bacteria, showed a selective inability in bactericidal activity against the patients' own P. aeruginosa isolate possibly reflecting the presence of \"bactericidal blocking\" antibodies.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"17 1","pages":"107-114"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89754474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
Freezing of rat lymphocytes. III. Freezing of plaque-forming cells and restoration by frozen-thawed normal cells of antibody production in irradiated rats. 大鼠淋巴细胞冷冻。3辐照大鼠斑块形成细胞的冷冻和抗体产生正常细胞的冻融修复。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1976.TB00060.X
E. Hem
{"title":"Freezing of rat lymphocytes. III. Freezing of plaque-forming cells and restoration by frozen-thawed normal cells of antibody production in irradiated rats.","authors":"E. Hem","doi":"10.1111/J.1699-0463.1976.TB00060.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00060.X","url":null,"abstract":"The present investigation is an extension of earlier work with dimethyl sulphoxide (DMSO) protected frozen-thawed rat lymphocytes. In the present work it is shown that some 85-90% of the haemolytic plaque-forming cells (PFC) survived the freeze-thaw process. Irradiated rats were restored with fresh and frozen-thawed cells and immunized against sheep red blood cells (SRBC). Evidence is presented that a restrictive control of the PFC response by suppressor cells present in the spleen cell suspension is lost during the freeze-thaw process, giving a higher number of PFC/spleen in recipients of frozen-thawed mixed spleen and lymph node cells than in rats receiving the corresponding fresh preparations.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"43 1","pages":"489-94"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73403026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
PHAGOCYTOSIS AND MICROBICIDAL CAPACITY OF MOUSE MACROPHAGES NON-SPECIFICALLY ACTIVATED IN VITRO 体外非特异性活化小鼠巨噬细胞的吞噬和杀微生物能力
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1975.TB01616.X
Å. Reikvam, E. Høiby
{"title":"PHAGOCYTOSIS AND MICROBICIDAL CAPACITY OF MOUSE MACROPHAGES NON-SPECIFICALLY ACTIVATED IN VITRO","authors":"Å. Reikvam, E. Høiby","doi":"10.1111/J.1699-0463.1975.TB01616.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1975.TB01616.X","url":null,"abstract":"Mouse macrophages cultured in a medium containing 50 per cent newborn calf serum (NBCS) were shown to undergo a characteristic development. Their size as well as their content of phase-lucent and phase-dense granules increased. The cell content of the lysosomal enzyme acid phosphatase was increased. In contrast, macrophages from the same source and cultured in a medium containing 50 per cent foetal calf serum (FCS) were not activated in this way. NBCS-activated macrophages had a markedly enhanced capacity to phagocytose Toxoplasma gondii and Listeria monocytogenes, as compared with macrophages cultured in FCS. However, their ability to restrict the intracellular multiplication of these micro-organisms was not markedly increased.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"83 1","pages":"121-128"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/J.1699-0463.1975.TB01616.X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63538283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Antibody-dependent cell-mediated cytotoxicity by activated thymocyte populations. Nature of the effector cell(s). 抗体依赖细胞介导的胸腺细胞活化的细胞毒性。效应细胞的性质。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1977.TB03641.X
B. Rubin, M. Høier‐Madsen
{"title":"Antibody-dependent cell-mediated cytotoxicity by activated thymocyte populations. Nature of the effector cell(s).","authors":"B. Rubin, M. Høier‐Madsen","doi":"10.1111/J.1699-0463.1977.TB03641.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB03641.X","url":null,"abstract":"The results of the present experiments have shown that activated thymocyte populations are endowed with a cytotoxic potential against antibody-coated target cells. The effector cells could be divided into at least two subpopulations. 1) host-derived macrophage-like cells and 2) thymocyte-derived donor cell T lymphocytes. These two subpopulations could be separated and identified by means of commonly used immunofractionation techniques. Such data show that effector cells which kill antibody-coated target cells may be of T cell nature.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"71 1","pages":"262-76"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74630536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Allo-aggression in chickens. II. Cellular expression of the AA gene products. 鸡的攻击性。2AA基因产物的细胞表达。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1976.TB00036.X
M. Crone, M. Simonsen
{"title":"Allo-aggression in chickens. II. Cellular expression of the AA gene products.","authors":"M. Crone, M. Simonsen","doi":"10.1111/J.1699-0463.1976.TB00036.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00036.X","url":null,"abstract":"B1-anti-B2 and B2-anti-B1 allo-antisera were raised by i.v. immunization of homozygous B1/1 and B2/2 chickens, respectively, with B1/2 cells of the following sources: peripheral blood leucocytes (PBL), erythrocytes, thymus cells and bursa cells. Purified suspensions of these all produced anti-B allo-antibodies which could both haemagglutinate red blood cells and strongly inhibit the GVH reactivity of blood lymphocytes of the original donor type. Absorption studies of the sera using cells of the same four sources showed that they could all completely remove the GVH inhibitory antibodies. A fact of particular importance is that B-haplotype determined antigens which are common to erythrocytes and lymphocytes seem to include the gene products of the allo-aggression locus, as earlier defined (Simonsen 1975).","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"65 1","pages":"319-24"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80201747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A "reverse" solid-phase radio-immuno-assay for IgM-antibodies to hepatitis A virus. A型肝炎病毒igm抗体的“反向”固相放射免疫测定。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1981.TB02668.X
O. Meurman, L. Matter, R. V. Krishna, U. Krech
{"title":"A \"reverse\" solid-phase radio-immuno-assay for IgM-antibodies to hepatitis A virus.","authors":"O. Meurman, L. Matter, R. V. Krishna, U. Krech","doi":"10.1111/J.1699-0463.1981.TB02668.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1981.TB02668.X","url":null,"abstract":"A \"reverse\"solid-phase radio-immuno-assay for IgM antibodies to hepatitis A virus (HAV) was developed. Anti-human IgM immunoglobulins were bound on the wells of polyvinylchloride microtiter plates. Serum specimens were incubated in the anti-human IgM coated wells and bound IgM antibodies were then assayed for antigen specificity by subsequent incubations with HAV antigen and 125I-labelled human anti-HAV IgG. The test showed a high sensitivity and specificity for anti-HAV IgM antibodies. No false-positive reactions were observed either in the sera from patients with hepatobiliary disorders other than HAV infection or in the sera containing both rheumatoid factor and anti-HAV IgG antibodies. In acute HAV infections specific IgM antibodies were present already in the first specimens taken within a few days after the onset of jaundice. The persistence of the IgM antibodies was from 4 to 6 months. IgM antibody titers up to 1,000,000 were observed in the acute phase of HAV infection. In routine diagnostic work the titration of the sea was not necessary, since a reliable qualitative result was obtained by testing the sera in a single dilution of 1:100. A similar \"reverse\" immuno-assay principle may be adaptable for the diagnostic determination of IgM antibodies to different viral and microbial antigens.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"9 28 1","pages":"79-84"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81158710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Experimental Escherichia coli 06 infection in mice. IV. On the relative importance of complement factors and antibodies for the host defence. 实验性小鼠大肠杆菌06感染。关于补体因子和抗体对宿主防御的相对重要性。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1981.TB02660.X
S. Ahlstedt
{"title":"Experimental Escherichia coli 06 infection in mice. IV. On the relative importance of complement factors and antibodies for the host defence.","authors":"S. Ahlstedt","doi":"10.1111/J.1699-0463.1981.TB02660.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1981.TB02660.X","url":null,"abstract":"Treatment of CBA mice with cobra venom factor (CVF) decreased their C3 levels to less than 10 per cent of normal and resulted in a simultaneous increase of their susceptibility to intraperitoneal E. coli 06 infection. Animals immunized and treated with CVF had an infection resistance similar to untreated controls but considerably less than mice immunized only. The CVF treatment did not affect the antibody formation after immunization. Untreated or immunized AKR mice deficient in C5 did not show decreased resistance to the infection. Exposure of NMRI mice to preformed antigen-antibody complexes unrelated to the infection did not increase the susceptibility of the animals to infection, neither did it impair their C3 levels. Two out of five freshly frozen (-70 degrees C) normal rabbit sera gave significant, heat-labile protection of mice to the E. coli infection without containing any antibodies detectable with the ELISA. This protective capacity was not abolished with zymosan treatment affecting the levels of complement factors and could be \"natural antibodies\" stimulated from the environment. In testing whether similar protective factors as those found in normal rabbit serum could be raised in CBA mice, such animals were orally given killed E. coli 06 bacteria. This did not affect the resistance to the E. coli infection or to the rise of specific antibodies after immunization.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"249 1","pages":"23-8"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75875590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The serology of Pseudomonas aeruginosa analysed by means of quantitative immunoelectrophoretic methods. V. Thermostability, resistance to degradation by plasmin activity and storage conditions of a polyvalent P. aeruginosa reference standard-antigen. 采用定量免疫电泳方法对铜绿假单胞菌进行血清学分析。V.一种多价铜绿假单胞菌参比标准抗原的热稳定性、抗纤溶酶活性降解性和储存条件。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1976.TB00045.X
N. Høiby
{"title":"The serology of Pseudomonas aeruginosa analysed by means of quantitative immunoelectrophoretic methods. V. Thermostability, resistance to degradation by plasmin activity and storage conditions of a polyvalent P. aeruginosa reference standard-antigen.","authors":"N. Høiby","doi":"10.1111/J.1699-0463.1976.TB00045.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1976.TB00045.X","url":null,"abstract":"The stability of a polyvalent Pseudomonas aeruginosa antigen (St-Ag) was analysed under different experimental conditions by quantitative immunoelectrophoretic methods. St-Ag did not undergo proteolytic degradation by plasmin which is present in the corresponding polyvalent rabbit antiserum (St-Ab) against St-Ag. Storage at -30 degrees C for up to 4 years caused no qualitative changes in St-Ag and, after 1 year, only minor quantitative changes could be revealed. Repeated thawing and freezing caused no changes in St-Ag whereas storage at 4 degrees C, or at room temperature, caused gradual degradation of most of the antigens of St-Ag, beginning after 1 week. Heating up to 40 degrees C for 2 min did not change St-Ag, but heating for longer periods of time or at higher temperatures gradually destroyed most of the antigens of St-Ag. The most thermostable antigen in St-Ag was number 37 which is related to the group specific O antigens.","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"15 1","pages":"383-9"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83633563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Quantitation of proenzyme C1r-C1s complexes in serum by electroimmunoassay. 电免疫法测定血清中C1r-C1s前酶复合物的含量。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1981-12-01
A B Laurell, U Mårtensson, A G Sjöholm
{"title":"Quantitation of proenzyme C1r-C1s complexes in serum by electroimmunoassay.","authors":"A B Laurell, U Mårtensson, A G Sjöholm","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"89 6","pages":"391-2"},"PeriodicalIF":0.0,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17341004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotics and granulocytes. Direct and indirect effects on granulocyte chemotaxis. 抗生素和粒细胞。对粒细胞趋化性的直接和间接影响。
Acta pathologica et microbiologica Scandinavica. Section C, Immunology Pub Date : 1981-08-01
J A Belsheim, G H Gnarpe
{"title":"Antibiotics and granulocytes. Direct and indirect effects on granulocyte chemotaxis.","authors":"J A Belsheim,&nbsp;G H Gnarpe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twelve antibiotics were investigated regarding both their direct in vitro influence on granulocyte chemotaxis, and their indirect effect on the production of chemotactic factors from cultures of Escherichia coli and Pseudomonas aeruginosa. None of the beta-lactam antibiotics studied caused significant alterations of granulocyte migratory response when incubated with the cells at concentrations of up to 128 microgram/ml. The two aminoglycoside preparations, and the two tetracycline preparations caused significant depressions of the migration response. Production of chemotactic factors was stimulated from growing cultures of E. coli by sub-minimal inhibitory concentrations of beta-lactam antibiotics and from Ps. aeruginosa by the cephalosporin derivatives only. The differences observed were most probably due to the mode of action at the bacterial cell wall level.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"89 4","pages":"217-21"},"PeriodicalIF":0.0,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17849122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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