Acta pathologica et microbiologica Scandinavica. Section C, Immunology最新文献

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In vitro locomotion of human leukocytes. Photographically determined distribution in millipore filters at different incubation times. 人白细胞的体外运动。照相测定分布在微孔过滤器在不同的孵育时间。
A Schreiner
{"title":"In vitro locomotion of human leukocytes. Photographically determined distribution in millipore filters at different incubation times.","authors":"A Schreiner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The distribution of leukocytes in Boyden millipore filters after stimulation with casein was determined after 30 and 180 min by the use of a photographic method. After 30 min the distribution was characterized by a second degree curve with a falling slope and after 180 min by a linear curve with a rising slope. The results showed that with most of the modifications of the Boyden method in use at present, the choice of incubation time is crucial for the evaluation of counting results.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"86C 3","pages":"117-21"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11572125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brief report. In vitro effects of Rubella virus, strain RA 27/3, on human lymphocytes. III. Inhibition of mitogen stimulation transferred by supernatants from virus-infected cultures. 简短的报告。风疹病毒RA 27/3株对人淋巴细胞的体外影响。3病毒感染培养物上清转移的有丝分裂原刺激的抑制作用。
R Maller, L Sörén
{"title":"Brief report. In vitro effects of Rubella virus, strain RA 27/3, on human lymphocytes. III. Inhibition of mitogen stimulation transferred by supernatants from virus-infected cultures.","authors":"R Maller,&nbsp;L Sörén","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>When lymphocytes from humans with serological immunity against rubella were incubated with live rubella virus, supernatants were obtained which when added to non-infected lymphocytes gave a significant inhibition of phytohaemagglutinin (PHA)-induced proliferation. In contrast, supernatants from virus-infected lymphocytes from donors lacking immunity against rubella gave no inhibition of the PHA response.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"86 2","pages":"89-91"},"PeriodicalIF":0.0,"publicationDate":"1978-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11898561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
B- and T-cells and intracellular Ig-synthesis of peripheral lymphocytes in children with asthma and/or previous adeno-tonsillectomy. 哮喘和/或既往腺扁桃体切除术儿童外周血淋巴细胞的B细胞和t细胞及细胞内igg合成
P A Ostergaard
{"title":"B- and T-cells and intracellular Ig-synthesis of peripheral lymphocytes in children with asthma and/or previous adeno-tonsillectomy.","authors":"P A Ostergaard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Studies of IgG, IgA and IgM in serum, the number of circulating T- and B-cells, and the number of Ig-containing blast cells after pokeweed mitogen stimulation of peripheral lymphocytes in vitro were performed in children who had been found previously to have low IgA levels in serum and saliva. The first group comprises 24 children with tonsillectomy performed approximately 3 1/2 years earlier, among whom several cases of atopic diseases had been found. In these children, low IgA levels were found continuously, while the numbers of B- and T-cells and the number of IgG, IgA, IgM and IgE-containing blast cells were within normal levels. The second group comprises 28 children with recurrent and chronic respiratory infections, which often preceded attacks of asthma. Very low IgA levels were found in these children associated with a decreased number of T-cells, increased numbers of lymphocytes with membrane bound IgA and IgE and an increased number of IgE-containing blast cells. The third group comprises 20 children with severe extrinsic asthma. In these children, slightly decreased levels of IgA and low levels of IgM were found. Furthermore, the number of circulating T-cells was reduced and, in addition, an increased number of lymphocytes with surface IgE was observed.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85C 6","pages":"454-62"},"PeriodicalIF":0.0,"publicationDate":"1977-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11517875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibody-dependent cell-mediated cytotoxicity by activated thymocyte populations. Nature of the effector cell(s). 抗体依赖细胞介导的胸腺细胞活化的细胞毒性。效应细胞的性质。
B Rubin, M Hoier-Madsen
{"title":"Antibody-dependent cell-mediated cytotoxicity by activated thymocyte populations. Nature of the effector cell(s).","authors":"B Rubin,&nbsp;M Hoier-Madsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The results of the present experiments have shown that activated thymocyte populations are endowed with a cytotoxic potential against antibody-coated target cells. The effector cells could be divided into at least two subpopulations. 1) host-derived macrophage-like cells and 2) thymocyte-derived donor cell T lymphocytes. These two subpopulations could be separated and identified by means of commonly used immunofractionation techniques. Such data show that effector cells which kill antibody-coated target cells may be of T cell nature.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85C 4","pages":"262-76"},"PeriodicalIF":0.0,"publicationDate":"1977-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11516172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutrophil granulocyte chemotaxis in vitro. Comparison of the response to casein and a bacterial chemotactic factor, and evaluation of an automatic method for counting cells on a membrane filter surface. 中性粒细胞体外趋化性研究。对酪蛋白和细菌趋化因子的反应比较,以及对膜过滤器表面细胞计数的自动方法的评价。
N H Valerius
{"title":"Neutrophil granulocyte chemotaxis in vitro. Comparison of the response to casein and a bacterial chemotactic factor, and evaluation of an automatic method for counting cells on a membrane filter surface.","authors":"N H Valerius","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A method is described for evaluating neutrophil granulocyte chemotaxis in vitro, using a modified reversible Boyden chamber. The variation in cell detachment from the attractant surface of the filter after the migration through the filter was shown to be eliminated by reversing the chambers during the incubation period. In unreversed chambers, the loss of cells from the bottom surface of the filter was much higher on attraction with casein than with a bacterial chemotactic factor (BCF). The finding of a different kinetic response to casein and to BCF may suggest differing affinity to various chemoattractants within circulating neutrophils. The results obtained after introducing an automatic quantitative image analysis system for the counting of the cells at the filter surface are found to be very well correlated to those with conventional direct microscope counting.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85C 4","pages":"289-96"},"PeriodicalIF":0.0,"publicationDate":"1977-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12083626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IgA levels and carrier rate of pathogenic bacteria in 27 children previously tonsillectomized. 27例扁桃体切除患儿IgA水平及致病菌携带率分析。
P A Ostergaard
{"title":"IgA levels and carrier rate of pathogenic bacteria in 27 children previously tonsillectomized.","authors":"P A Ostergaard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The object of the present paper is to present laboratory and clinical data on 27 children of ages between 6 and 11 years, who in connection with tonsillectomy 2 1/2 years earlier had been found to have low serum and saliva IgA levels, low serum IgE levels, and a considerable lack of IgA and IgE plasma cells in the excised tonsils; correlation between deficiency in IgA and culture of pathogenic bacteria from the tonsils was significant. From a clinical point of view, 22 of the children had benefit of the tonsillectomy and had no longer a tendency towards a development of recurrent infections. The remaining 5 patients continued to complain of recurring respiratory infections; in addition, levels of serum and saliva IgA were low. Furthermore, 4 or these 5 children harboured pathogenic bacteria in their throats. Many of the 27 patients still had low serum IgA and IgE levels as compared with levels in healthy, age-related controls; in 3 patients, however, the IgE levels in serum had risen considerably parallel with the development of atopic diseases. Saliva IgA was rather constant after tonsillectomy as compared with the preoperative levels, though it had risen in some of the children. As regards serum IgG and IgM, these immunoglobulins had decreased significantly, and the question is raised, whether it might had been due to the tonsillectomy, either by the removal of chronically infected organs or by the removal of important immunological tissue.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85 3","pages":"178-86"},"PeriodicalIF":0.0,"publicationDate":"1977-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12061767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IgA levels, bacterial carrier rate, and the development of bronchial asthma in children. IgA水平、细菌携带率与儿童支气管哮喘的发展。
P A Ostergaard
{"title":"IgA levels, bacterial carrier rate, and the development of bronchial asthma in children.","authors":"P A Ostergaard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A total of 54 children, earlier hospitalized for asthma, were reinvestigated with regard to immunoglobulin formation in serum and saliva. Furthermore, the carrier rate of pathogenic bacteria in their throats was investigated, and in some of the children, who had their adenoids removed, immunofluorescent studies were performed. The study revealed highly reduced levels of serum and saliva IgA in the younger children with asthma. In addition, in these children a connection between recurring respiratory infections and high carrier rate of presumably pathogenic bacteria was observed. Also in the older children, significantly reduced levels of serum and saliva IgA compared with age related controls were found, but these children did not have an increased frequency of pathogenic bacteria or repiratory infections. In addition, low levels of serum IgM were found in the older children with asthma. The results of the study support the theory that low IgA levels facilitate the entrance of pathogenic bacteria through the epithelial surfaces, resulting in an overstimulation of the IgE system and the development of bronchial asthma in the younger children. In the younger as well as the older patients, a high frequency of atopy among the closest relatives was observed.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85 3","pages":"187-95"},"PeriodicalIF":0.0,"publicationDate":"1977-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11540946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed hypersensitivity and borderline essential hypertension. 迟发性超敏反应和交界性原发性高血压。
F Olsen, S Rasmussen
{"title":"Delayed hypersensitivity and borderline essential hypertension.","authors":"F Olsen,&nbsp;S Rasmussen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By means of the leucocyte migration technique, it has been demonstrated that the migration indices from 19 patients suffering from borderline essential hypertension are significantly different from those of 19 normal persons. These results support the view that delayed hypersensitivity directed against arterial wall components is a possible pathogenetic factor in patients suffering from essential hypertension.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85 3","pages":"196-8"},"PeriodicalIF":0.0,"publicationDate":"1977-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12061768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudomonas aeruginosa infection in cystic fibrosis. Relative prevalence of antibodies in serum against cathodic and anodic migrating P. aeruginosa antigens determined by immunoelectrophoretic methods. 囊性纤维化中的铜绿假单胞菌感染。用免疫电泳法测定血清中抗阴极和阳极迁移铜绿假单胞菌抗原抗体的相对流行率。
N Holby
{"title":"Pseudomonas aeruginosa infection in cystic fibrosis. Relative prevalence of antibodies in serum against cathodic and anodic migrating P. aeruginosa antigens determined by immunoelectrophoretic methods.","authors":"N Holby","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sera from 119 patients with cystic fibrosis were examined for precipitating antibodies against anodic migrating P. aeruginosa antigens by means of crossed immunoelectrophoresis. The presence of precipitins against cathodic migrating P. aeruginosa antigens was investigated by means of classical immunoelectrophoresis. Thirty-six per cent of the sera contained precipitins against both anodic and cathodic antigens, 20% contained only precipitins against anodic antigens, none contained only precipitins against cathodic antigens, and 44% had no demonstrable P. aeurginosa precipitins. The amount of extra information obtained by combining the results of classical immunoelectrophoresis with the results of crossed immunoelectrophoresis was small.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85 2","pages":"149-52"},"PeriodicalIF":0.0,"publicationDate":"1977-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11289300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibodies against Pseudomonas aeruginosa in serum from normal persons and patients colonized with mucoid or non-mucoid Pseudomonas aeruginosa: Results obtained by crossed immunoelectrophoresis. 粘液样或非粘液样铜绿假单胞菌定植的正常人和患者血清中铜绿假单胞菌抗体:交叉免疫电泳结果。
N Holby
{"title":"Antibodies against Pseudomonas aeruginosa in serum from normal persons and patients colonized with mucoid or non-mucoid Pseudomonas aeruginosa: Results obtained by crossed immunoelectrophoresis.","authors":"N Holby","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum from 154 normal persons was investigated for precipitating antibodies against P. aeruginosa by crossed immunoelectrophoresis, using a polyvalent P. aeruginosa standard antigen. Ninety-four per cent of the sera contained no demonstrable precipitins, and 6% contained precipitins against only one P. aeruginosa antigen. Thirty-four per cent of sera from 122 patients colonized with P. aeruginosa in various anatomical regions contained precipitins against 2 to 41 P. aeruginosa antigens. Serum from 14 patients harbouring mucoid strains of P. aeruginsa contained precipitants against these bacteria, and the average number of precipitins was significantly higher than the average number of precipitins in serum from patients harbouring non-mucoid strains. The largest number of precipitins was found in serum from adult patients chronically colonized with mucoid P. aeruginosa in the lower respiratory tract, and from adult patients with P. aeruginosa bacteremia originating from suppurative urinary tract infections caused by mucoid strains. Serum from patients with P. aeruginosa cystitis or from patients with P. aeruginosa colonization of the middle ear or with wound infection, contained only few or no precipitins.</p>","PeriodicalId":75411,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section C, Immunology","volume":"85 2","pages":"142-8"},"PeriodicalIF":0.0,"publicationDate":"1977-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11612938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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