简短的报告。风疹病毒RA 27/3株对人淋巴细胞的体外影响。3病毒感染培养物上清转移的有丝分裂原刺激的抑制作用。

R Maller, L Sörén
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引用次数: 0

摘要

将对风疹具有血清学免疫的人淋巴细胞与风疹活病毒孵育,获得上清液,当将上清液加入未感染的淋巴细胞时,上清液对植物血凝素(PHA)诱导的增殖有显著的抑制作用。相反,来自缺乏风疹免疫的供体的病毒感染淋巴细胞的上清液对PHA反应没有抑制作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Brief report. In vitro effects of Rubella virus, strain RA 27/3, on human lymphocytes. III. Inhibition of mitogen stimulation transferred by supernatants from virus-infected cultures.

When lymphocytes from humans with serological immunity against rubella were incubated with live rubella virus, supernatants were obtained which when added to non-infected lymphocytes gave a significant inhibition of phytohaemagglutinin (PHA)-induced proliferation. In contrast, supernatants from virus-infected lymphocytes from donors lacking immunity against rubella gave no inhibition of the PHA response.

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