一种对克雷伯氏菌血清型12和13具有特异性抗体反应性的单克隆IgM

J. Eriksen, M. Harboe, Johanna Deverili
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引用次数: 2

摘要

从人大球蛋白血症血清Ra中提取的单克隆IgM对克雷伯氏菌12型和13型特异性多糖具有抗体活性。同样的igm分子沉淀了两种多糖。这两种克雷伯菌之间的交叉反应以前未见报道。兔高免疫血清也可以通过被动血凝反应来证明这一点,但不能通过凝胶沉淀或荚膜肿胀来证明。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A MONOCLONAL IgM WITH SPECIFIC ANTIBODY REACTIVITY AGAINST KLEBSIELLA SERO‐TYPES 12 AND 13
Monoclonal IgM from the human macroglobulinaemia serum Ra showed antibody activity against type specific polysaccharide from Klebsiella type 12 and type 13. The same IgM-molecule precipitated both polysaccharides. Cross-reaction between these two Klebsiella types has not been reported previously. It could also be demonstrated with rabbit hyperimmune sera by the passive haemagglutination reaction, but not by gel precipitation or capsular swelling.
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