Aging, Neuropsychology, and Cognition最新文献_第9页

Subjective cognitive complaints in White and African American older adults: associations with demographic, mood, cognitive, and neuroimaging features. 白人和非裔美国老年人的主观认知主诉:与人口统计学、情绪、认知和神经影像学特征的关系

IF 1.6 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 Epub Date: 2023-08-21 DOI: 10.1080/13825585.2023.2249181

Felicia C Goldstein, Maureen Okafor, Zhiyi Yang, Tiffany Thomas, Sabria Saleh, Ihab Hajjar

{"title":"Subjective cognitive complaints in White and African American older adults: associations with demographic, mood, cognitive, and neuroimaging features.","authors":"Felicia C Goldstein, Maureen Okafor, Zhiyi Yang, Tiffany Thomas, Sabria Saleh, Ihab Hajjar","doi":"10.1080/13825585.2023.2249181","DOIUrl":"10.1080/13825585.2023.2249181","url":null,"abstract":"Subjective cognitive complaints (SCC) in cognitively intact older adults have been investigated as a clinically important symptom that may portend the onset of a neurodegenerative disorder such as Alzheimer's disease. Few studies have concurrently incorporated demographic features, depressive symptoms, neuropsychological status, and neuroimaging correlates of SCC and evaluated whether these differ in White and African American older adults. In the current study, 131 (77 White, 54 African American) healthy participants ≥50 years old completed the Cognitive Function Instrument (CFI) to assess SCC, and they underwent objective cognitive testing, assessment of mood, and brain magnetic resonance imaging. Pearson Product Moment correlations were performed to evaluate associations of the CFI self-ratings with the above measures for the combined group and separately for White and African American participants. SCC were associated with greater depressive symptoms in both White and African American participants in adjusted models controlling for overall cognitive status, education, and hypertension. Greater white matter hyperintensities, lower cortical thickness, older age, and slower set shifting speed were associated with increased SCC in White participants. Although the correlations were not significant for African Americans, the strength of the associations were comparable to White participants. Hippocampal volume was not associated with either total SCC or items specific to memory functioning in the entire group. Longitudinal studies are needed to further evaluate the clinical significance of these associations with risk of conversion to mild cognitive impairment and dementia.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":" ","pages":"957-970"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10843657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10150880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitivity of memory subtests and learning slopes from the ADAS-Cog to distinguish along the continuum of the NIA-AA Research Framework for Alzheimer's Disease. 从ADAS-Cog的记忆子测试和学习斜率的敏感性来区分NIA-AA研究框架对阿尔茨海默病的连续性。

IF 1.6 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 Epub Date: 2022-09-08 DOI: 10.1080/13825585.2022.2120957

Dustin B Hammers, Ralitsa V Kostadinova, Robert J Spencer, Jean N Ikanga, Frederick W Unverzagt, Shannon L Risacher, Liana G Apostolova

{"title":"Sensitivity of memory subtests and learning slopes from the ADAS-Cog to distinguish along the continuum of the NIA-AA Research Framework for Alzheimer's Disease.","authors":"Dustin B Hammers, Ralitsa V Kostadinova, Robert J Spencer, Jean N Ikanga, Frederick W Unverzagt, Shannon L Risacher, Liana G Apostolova","doi":"10.1080/13825585.2022.2120957","DOIUrl":"10.1080/13825585.2022.2120957","url":null,"abstract":"Despite extensive use of the Alzheimer's Disease (AD) Assessment Scale - Cognitive Subscale (ADAS-Cog) in AD research, exploration of memory subtests or process scores from the measure has been limited. The current study sought to establish validity for the ADAS-Cog Word Recall Immediate and Delayed Memory subtests and learning slope scores by showing that they are sensitive to AD biomarker status. Word Recall subtest and learning slope scores were calculated for 441 participants from the Alzheimer's Disease Neuroimaging Initiative (aged 55 to 90). All participants were categorized using the NIA-AA Research Framework - based on PET-imaging of β-amyloid (A) and tau (T) deposition - as Normal AD Biomarkers (A-T-), Alzheimer's Pathologic Change (A + T-), or Alzheimer's disease (A + T+). Memory subtest and learning slope performances were compared between biomarker status groups, and with regard to how well they discriminated samples with (A + T+) and without (A-T-) biomarkers. Lower Word Recall memory subtest scores - and scores for a particular learning slope calculation, the Learning Ratio - were observed for the AD (A + T+) group than the other biomarker groups. Memory subtest and Learning Ratio scores further displayed fair to good receiver operator characteristics when differentiating those with and without AD biomarkers. When comparing across learning slopes, the Learning Ratio metric consistently outperformed others. ADAS-Cog memory subtests and the Learning Ratio score are sensitive to AD biomarker status along the continuum of the NIA-AA Research Framework, and the results offer criterion validity for use of these subtests and process scores as unique markers of memory capacity.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":" ","pages":"866-884"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9992455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9076214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between cognitive reserve, brain volume, and neuropsychological performance in amnestic and nonamnestic MCI. 遗忘型和非遗忘型轻度认知损伤中认知储备、脑容量和神经心理表现的关系。

IF 1.6 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 Epub Date: 2022-12-26 DOI: 10.1080/13825585.2022.2161462

K Reiter, A M Butts, J K Janecek, A N Correro, A Nencka, M Agarwal, M Franczak, L Glass Umfleet

{"title":"Relationship between cognitive reserve, brain volume, and neuropsychological performance in amnestic and nonamnestic MCI.","authors":"K Reiter, A M Butts, J K Janecek, A N Correro, A Nencka, M Agarwal, M Franczak, L Glass Umfleet","doi":"10.1080/13825585.2022.2161462","DOIUrl":"10.1080/13825585.2022.2161462","url":null,"abstract":"Cognitive Reserve (CR) is a theoretical construct that influences the onset and course of cognitive and structural changes that occur with aging and mild cognitive impairment (MCI). There is a paucity of research that examines the relationship of CR and brain volumes in amnestic (aMCI) and nonamnestic (naMCI) separately. This study is a retrospective chart review of MCI patients who underwent neuropsychological evaluation and brain MRI with NeuroReader™ (NR). NR is an FDA-cleared software that standardizes MRI volumes to a control sample. Classifications of aMCI and naMCI were based on Petersen criteria. CR was measured as education, occupation, and word reading. Data analysis included bivariate correlations between CR, neuropsychological test scores, and NR-brain volumes by MCI subtype. The Benjamini-Hochberg method corrected for multiple comparisons. The sample included 91 participants with aMCI and 41 with naMCI. Within naMCI, positive correlations were observed between CR and whole brain volume, total gray matter, bifrontal, left parietal, left occipital, and bilateral cerebellum. Within aMCI, no significant correlations were observed between CR and brain volumes. Positive correlations with CR were observed in language, attention, and visual learning in both aMCI and naMCI groups. The current study adds to the minimal literature on CR and naMCI. Results revealed that CR is associated with volumetrics in naMCI only, though cognitive findings were similar in both MCI groups. Possible explanations include heterogeneous disease pathologies, disease stage, or a differential influence of CR on volumetrics in MCI. Additional longitudinal and biomarker studies will better elucidate this relationship.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":" ","pages":"940-956"},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10445308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fostering cognitive performance in older adults with a process- and a strategy-based cognitive training. 以过程和策略为基础的认知训练促进老年人的认知表现。

IF 1.9 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 DOI: 10.1080/13825585.2022.2105298

Barbara Studer-Luethi, Valérie Boesch, Simon Lusti, Beat Meier

引用次数: 2

Executive function and episodic memory composite scores in older adults: relations with sex, mood, and subjective sleep quality. 老年人的执行功能和情景记忆综合评分：与性别、情绪和主观睡眠质量的关系。

IF 1.6 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 Epub Date: 2022-06-23 DOI: 10.1080/13825585.2022.2086682

Patrick S R Davidson, Adelaide Jensen

引用次数: 0

Procedural learning and retention relative to explicit learning and retention in mild cognitive impairment and Alzheimer's disease using a modification of the trail making test. 程序性学习和保留相对于显性学习和保留在轻度认知障碍和阿尔茨海默病中使用修改的轨迹测试。

IF 1.9 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 DOI: 10.1080/13825585.2022.2077297

Cierra M Keith, William T McCuddy, Katharine Lindberg, Liv E Miller, Kirk Bryant, Rashi I Mehta, Kirk Wilhelmsen, Mark Miller, R Osvaldo Navia, Melanie Ward, Gerard Deib, Pierre-François D'Haese, Marc W Haut

{"title":"Procedural learning and retention relative to explicit learning and retention in mild cognitive impairment and Alzheimer's disease using a modification of the trail making test.","authors":"Cierra M Keith, William T McCuddy, Katharine Lindberg, Liv E Miller, Kirk Bryant, Rashi I Mehta, Kirk Wilhelmsen, Mark Miller, R Osvaldo Navia, Melanie Ward, Gerard Deib, Pierre-François D'Haese, Marc W Haut","doi":"10.1080/13825585.2022.2077297","DOIUrl":"https://doi.org/10.1080/13825585.2022.2077297","url":null,"abstract":"Amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD) dementia are characterized by pathological changes to the medial temporal lobes, resulting in explicit learning and retention reductions. Studies demonstrate that implicit/procedural memory processes are relatively intact in these populations, supporting different anatomical substrates for differing memory systems. This study examined differences between explicit and procedural learning and retention in individuals with aMCI and AD dementia relative to matched healthy controls. We also examined anatomical substrates using volumetric MRI. Results revealed expected difficulties with explicit learning and retention in individuals with aMCI and AD with relatively preserved procedural memory. Explicit verbal retention was associated with medial temporal cortex volumes. However, procedural retention was not related to medial temporal or basal ganglia volumes. Overall, this study confirms the dissociation between explicit relative to procedural learning and retention in aMCI and AD dementia and supports differing anatomical substrates.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":"30 5","pages":"669-686"},"PeriodicalIF":1.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10064514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Introductory editorial to the special issue: Alzheimer's disease biomarkers and cognitive functioning along the Alzheimer's continuum. 特刊导论社论:阿尔茨海默病生物标志物和认知功能沿阿尔茨海默病的连续性。

IF 1.6 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-09-01 Epub Date: 2023-08-26 DOI: 10.1080/13825585.2023.2249190

Alissa M Butts, Marc W Haut

引用次数: 0

IF 1.9 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-07-01 DOI: 10.1080/13825585.2022.2067319

Claudia Bonmassar, Francesco Pavani, Domenico Spinella, Giuseppe Nicolò Frau, Wieske van Zoest

{"title":"Does age-related hearing loss deteriorate attentional resources?","authors":"Claudia Bonmassar, Francesco Pavani, Domenico Spinella, Giuseppe Nicolò Frau, Wieske van Zoest","doi":"10.1080/13825585.2022.2067319","DOIUrl":"https://doi.org/10.1080/13825585.2022.2067319","url":null,"abstract":"Recent work suggests that age-related hearing loss (HL) is a possible risk factor for cognitive decline in older adults. Resulting poor speech recognition negatively impacts cognitive, social and emotional functioning and may relate to dementia. However, little is known about the consequences of hearing loss on other non-linguistic domains of cognition. The aim of this study was to investigate the role of HL on covert orienting of attention, selective attention and executive control. We compared older adults with and without mild to moderate hearing loss (26-60 dB) performing (1) a spatial cueing task with uninformative central cues (social vs. nonsocial cues), (2) a flanker task and (3) a neuropsychological assessment of attention. The results showed that overall response times and flanker interference effects were comparable across groups. However, in spatial cueing of attention using social and nonsocial cues, hearing impaired individuals were characterized by reduced validity effects, though no additional group differences were found between social and nonsocial cues. Hearing impaired individuals also demonstrated diminished performance on the Montreal Cognitive Assessment (MoCA) and on tasks requiring divided attention and flexibility. This work indicates that while response speed and response inhibition appear to be preserved following mild-to-moderate acquired hearing loss, orienting of attention, divided attention and the ability to flexibly allocate attentional resources are more deteriorated in older adults with HL. This work suggests that hearing loss might exacerbate the detrimental influences of aging on visual attention.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":"30 4","pages":"601-619"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9481142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Acquisition and consolidation of verbal learning and episodic memory as predictors of the conversion from mild cognitive impairment to probable Alzheimer's disease. 语言学习和情景记忆的习得和巩固是轻度认知障碍向可能的阿尔茨海默病转变的预测因素。

IF 1.9 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-07-01 DOI: 10.1080/13825585.2022.2069670

Jorge López-Pérez, Sara García-Herranz, María Del Carmen Díaz-Mardomingo

{"title":"Acquisition and consolidation of verbal learning and episodic memory as predictors of the conversion from mild cognitive impairment to probable Alzheimer's disease.","authors":"Jorge López-Pérez, Sara García-Herranz, María Del Carmen Díaz-Mardomingo","doi":"10.1080/13825585.2022.2069670","DOIUrl":"https://doi.org/10.1080/13825585.2022.2069670","url":null,"abstract":"Verbal episodic memory tests assess memory performance using total learning scores. The analysis of inter-trial indices such as gained (GA) and lost (LA) access can provide additional information on the acquisition and consolidation processes. The main objetive was to determine whether the GA and LA indices, derived from a word-list verbal episodic memory test are useful for predicting cognitive impairment in aging. 60 older people aged was divided into 3 groups: cognitively healthy, stable Mild Cognitive Impairment (MCI) and MCI converting to probable Alzheimer's disease (MCI-conv). The results showed that GA and LA measures are independent from the traditional measures -total score of correct answers-. Logistic regression showed that these values are predictive of the conversion over time and could be a cognitive marker of conversion from MCI to AD. This suggests that the GA index, which shows acquisition processes in word-list tests, may be a marker of cognitive impairment.","PeriodicalId":7532,"journal":{"name":"Aging, Neuropsychology, and Cognition","volume":"30 4","pages":"638-653"},"PeriodicalIF":1.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9483032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The effects of simulated and actual visual impairment on the Montreal Cognitive Assessment. 模拟和实际视觉损伤对蒙特利尔认知评估的影响。

IF 1.9 4区心理学

Aging, Neuropsychology, and Cognition Pub Date : 2023-07-01 DOI: 10.1080/13825585.2022.2055739

Zoey Stark, Elliot Morrice, Caitlin Murphy, Walter Wittich, Aaron P Johnson

引用次数: 0