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Aktuelle Urologie最新文献

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[Digital health for benign prostate syndrome]. [良性前列腺综合症的数字健康]
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-05-05 DOI: 10.1055/a-2573-7302
Sandra Helen Schönburg
{"title":"[Digital health for benign prostate syndrome].","authors":"Sandra Helen Schönburg","doi":"10.1055/a-2573-7302","DOIUrl":"https://doi.org/10.1055/a-2573-7302","url":null,"abstract":"<p><p>In addition to drugs, remedies and medical aids, digital health applications are a new therapeutic area according to §33a SGB V. There are now 69 approved DiGA listed in the BfArM DiGA directory, 40 of them permanently. The approval and listing of a DiGA is the result of a randomised control trial (RCT) with corresponding proof of effectiveness. Kranus Lutera is the first approved DiGA for male lower urinary tract symptoms (LUTS). The BEST study provided proof of effectiveness. A total of 237 patients were randomised in this study. Compared to the control group, the intervention group showed a significant improvement in the primary endpoint IPSS (-7.0; 95% CI: -8.1; -5.9; p<0.0001) and the secondary endpoints OAB-q-SF part 1 (symptom burden: -18.6; 95% CI: -22.2; -15.0; p<0.0001) and part 2 (health-related quality of life: +17.2; 95% CI: 20.16; 14.8; p<0.0001). The two subgroups (BPH, OAB) benefited similarly.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bladder sparing options for muscle invasive high risk bladder cancer]. [肌肉浸润性高风险膀胱癌的膀胱保留选择]。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-05-05 DOI: 10.1055/a-2586-5554
Oliver Hahn, Hubert Kübler
{"title":"[Bladder sparing options for muscle invasive high risk bladder cancer].","authors":"Oliver Hahn, Hubert Kübler","doi":"10.1055/a-2586-5554","DOIUrl":"https://doi.org/10.1055/a-2586-5554","url":null,"abstract":"<p><p>Radical cystectomy is not a suitable option for every patient with muscle-invasive bladder cancer. Whereas radiotherapy (in combination with radio-sensitizing chemotherapy) is mentioned as an alternative in the current German S3 guideline, numbers are low in Germany compared to other countries. We try here to sum up the current evidence and data, especially regarding the definition of on optimal patient population to profit from this kind of therapy. Furthermore, we take a look at the role of cystectomy in the age of modern tumour therapy.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Thrombophlebitis of the superficial dorsal penile vein following a long-haul flight: a case report of penile Mondor's disease without classical risk factors]. [长途飞行后阴茎浅背静脉血栓性静脉炎：无典型危险因素的阴茎蒙多氏病1例报告]。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-29 DOI: 10.1055/a-2578-3978
Julio Rodas Garzaro, Mirigbal Mirizada, Johannes Moersler, Matthias May, Christian Gilfrich, Anton Kravchuk
{"title":"[Thrombophlebitis of the superficial dorsal penile vein following a long-haul flight: a case report of penile Mondor's disease without classical risk factors].","authors":"Julio Rodas Garzaro, Mirigbal Mirizada, Johannes Moersler, Matthias May, Christian Gilfrich, Anton Kravchuk","doi":"10.1055/a-2578-3978","DOIUrl":"https://doi.org/10.1055/a-2578-3978","url":null,"abstract":"<p><p>Penile Mondor's disease (PMD) is a rare, typically self-limiting superficial thrombophlebitis of the dorsal penile vein. Common risk factors include intensive sexual activity, penile trauma, and coagulation disorders. We report the first documented case of PMD occurring after a long-haul flight associated with prolonged immobilisation. A 29-year-old male patient presented with an acute, painful swelling of the penile shaft following a transatlantic long-haul flight. Clinical examination revealed a cord-like induration along the dorsal penile vein. Doppler ultrasonography demonstrated a 4 cm-long hypoechogenic structure within the superficial dorsal penile vein, with no detectable venous flow signals in this region. Subsequent magnetic resonance imaging ruled out involvement of the deep penile vein, the external pudendal veins, and the pelvic veins. Conservative management with nonsteroidal anti-inflammatory drugs, topical heparin ointment application, and anticoagulation with low-molecular-weight heparin - later transitioned to an oral factor Xa inhibitor - resulted in complete remission within four weeks. This case underscores the importance of early diagnosis and conservative management of PMD. Prolonged immobilisation should be recognised as a potential risk factor. Prophylactic administration of low molecular weight heparin prior to long-haul flights may be considered in at-risk patients.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ex-vivo Comparative Study on the Morcellation Efficiency of Different Morcellators]. [不同粉碎器粉碎效率的离体比较研究]。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-23 DOI: 10.1055/a-2560-3827
Benedikt Becker, Christopher Netsch, Andreas J Gross, Clemens Rosenbaum, Friedrich Otto Hartung, Simon Filmar, Sophia Hook
{"title":"[Ex-vivo Comparative Study on the Morcellation Efficiency of Different Morcellators].","authors":"Benedikt Becker, Christopher Netsch, Andreas J Gross, Clemens Rosenbaum, Friedrich Otto Hartung, Simon Filmar, Sophia Hook","doi":"10.1055/a-2560-3827","DOIUrl":"https://doi.org/10.1055/a-2560-3827","url":null,"abstract":"<p><p>Anatomical enucleation of the prostate (AEEP) is an established treatment option for benign prostatic hyperplasia (BPH), regardless of prostate size. While advancements in laser technology have significantly improved the enucleation phase, the morcellation process has remained relatively unchanged, with limited innovations in morcellation devices. This study aimed to compare the efficiency of two morcellators in an ex-vivo model: the Piranha morcellator (Richard Wolf GmbH, Knittlingen) and a newly introduced, yet-to-be-commercialized device, the ActiveCut morcellator (Active Fiber Systems GmbH, Jena).The two morcellators were tested in a newly developed ex-vivo model. In both groups, reusable blades were tested ten times at comparable speed settings. For each trial, 60 grams of raw bovine heart tissue were morcellated. The efficiency of the morcellation was then analyzed. Primary endpoints included morcellation efficiency (g/min) and an evaluation of blade deterioration over repeated use. The mean values of continuous variables were compared using a t-test with standard deviation.A total of ten consecutive morcellation trials were conducted with each device. The ActiveCut demonstrated higher morcellation rates at 12.43 g/min, compared to 7.09 g/min with the Piranha morcellator (p<0.05). However, the ActiveCut showed a decline in efficiency over ten trials. In two cases, tissue had to be manually removed from the blade coupling during morcellation, whereas the Piranha morcellator maintained consistent performance without malfunctions.In this ex-vivo study, comparing the ActiveCut and Piranha morcellators, the ActiveCut exhibited higher morcellation efficiency. However, as the ActiveCut has not yet undergone clinical testing, future clinical studies are necessary to assess its safety and potential malfunctions before clinical implementation.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Gender-/Sex-Specific Differences in Clinical Trials in Uro-Oncology]. [泌尿肿瘤临床试验中性别/性别特异性差异]。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI: 10.1055/a-2510-9757
Marie Christine Roesch, Lea Sophie Lütje, Nils Gilbert, Axel Stuart Merseburger, Daniar Osmonov
{"title":"[Gender-/Sex-Specific Differences in Clinical Trials in Uro-Oncology].","authors":"Marie Christine Roesch, Lea Sophie Lütje, Nils Gilbert, Axel Stuart Merseburger, Daniar Osmonov","doi":"10.1055/a-2510-9757","DOIUrl":"10.1055/a-2510-9757","url":null,"abstract":"<p><p>Subgroup analyses in clinical trials sometimes reveal gender-/sex-dependent differences in cancer outcomes. However, drug approvals are rarely restricted to a specific sex or gender, and recommendations regarding dosage are rarely tailored accordingly. Furthermore, discrepancies exist between the gender-/sex-dependent enrollment rates in clinical trials and real-world incidence or mortality rates. This article highlights gender-/sex differences in clinical trials in uro-oncology.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"131-134"},"PeriodicalIF":0.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143057776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kommentar. .评论
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2463-1747
{"title":"Kommentar.","authors":"","doi":"10.1055/a-2463-1747","DOIUrl":"https://doi.org/10.1055/a-2463-1747","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 2","pages":"116-118"},"PeriodicalIF":0.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Die Zukunft der geschlechtsspezifischen Urologie – Wissenschaftliche Evidenz, Medizin und Gesellschaft. 性别泌尿学的未来：科学证据，医学和社会。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2467-7721
Shahrokh F Shariat, Robert J Schulz
{"title":"Die Zukunft der geschlechtsspezifischen Urologie – Wissenschaftliche Evidenz, Medizin und Gesellschaft.","authors":"Shahrokh F Shariat, Robert J Schulz","doi":"10.1055/a-2467-7721","DOIUrl":"https://doi.org/10.1055/a-2467-7721","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 2","pages":"105-106"},"PeriodicalIF":0.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ureterorenoskopie und Steinextraktion/Lithotripsie. 输尿管镜检查和取石/碎石术。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2315-4793
Manuel Ritter
{"title":"Ureterorenoskopie und Steinextraktion/Lithotripsie.","authors":"Manuel Ritter","doi":"10.1055/a-2315-4793","DOIUrl":"https://doi.org/10.1055/a-2315-4793","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 2","pages":"179-189"},"PeriodicalIF":0.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urolithiasis: Bestimmung des Steinvolumens mithilfe Künstlicher Intelligenz. 尿石症：利用人工智能确定结石体积。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2321-2450
{"title":"Urolithiasis: Bestimmung des Steinvolumens mithilfe Künstlicher Intelligenz.","authors":"","doi":"10.1055/a-2321-2450","DOIUrl":"https://doi.org/10.1055/a-2321-2450","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 2","pages":"120-121"},"PeriodicalIF":0.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjuvante Therapie des Hochrisiko-Urothelkarzinom von Blase oder oberem Harntrakt nach radikaler Resektion. 根治性切除后高危膀胱癌或上尿道癌的辅助治疗。
IF 0.3 4区 医学
Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2467-7694
{"title":"Adjuvante Therapie des Hochrisiko-Urothelkarzinom von Blase oder oberem Harntrakt nach radikaler Resektion.","authors":"","doi":"10.1055/a-2467-7694","DOIUrl":"https://doi.org/10.1055/a-2467-7694","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"56 2","pages":"128-129"},"PeriodicalIF":0.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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