[泌尿肿瘤临床试验中性别/性别特异性差异]。

IF 0.3 4区医学 Q4 UROLOGY & NEPHROLOGY

Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI:10.1055/a-2510-9757

Marie Christine Roesch, Lea Sophie Lütje, Nils Gilbert, Axel Stuart Merseburger, Daniar Osmonov

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引用次数: 0

摘要

临床试验中的亚组分析有时会揭示癌症结局的性别/性别依赖差异。然而，药物批准很少局限于特定的性别或性别，有关剂量的建议也很少相应地调整。此外，临床试验中性别/性别依赖的入组率与现实世界的发病率或死亡率之间存在差异。这篇文章强调了泌尿肿瘤临床试验中的性别差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Gender-/Sex-Specific Differences in Clinical Trials in Uro-Oncology].

Subgroup analyses in clinical trials sometimes reveal gender-/sex-dependent differences in cancer outcomes. However, drug approvals are rarely restricted to a specific sex or gender, and recommendations regarding dosage are rarely tailored accordingly. Furthermore, discrepancies exist between the gender-/sex-dependent enrollment rates in clinical trials and real-world incidence or mortality rates. This article highlights gender-/sex differences in clinical trials in uro-oncology.

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来源期刊

Aktuelle Urologie 医学-泌尿学与肾脏学

CiteScore

0.60

自引率

33.30%

发文量

104

审稿时长

>12 weeks

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