{"title":"[Cobb's collar … seek and you shall find!]","authors":"Evi Comploj, Christian Ladurner, Armin Pycha","doi":"10.1055/a-2466-6115","DOIUrl":"https://doi.org/10.1055/a-2466-6115","url":null,"abstract":"<p><strong>Purpose: </strong>Cobb's collar, also known as Moormann's ring, is a rare membranous stricture of the bulbar urethra. In contrast to the posterior urethral valve (PUV), Cobb's collar is not connected to the verumontanum. A simultaneous occurrence of PUV and Cobb's collar is even rarer. To the best of our knowledge, we report the third case in the literature of a child with coexistence of PUV and Cobb's collar.</p><p><strong>Case presentation: </strong>We present the case of a 3-year-old boy with a history of recurrent episodes of bladder outlet obstruction with residual urine volumes of up to 800 ml. An outward cystoscopy only revealed a bladder neck with a spastic appearance. A neuropediatric visit was unremarkable; magnetic resonance imaging (MRI) of the brain and spine was negative. After the positioning of a suprapubic catheter, cystoscopy was repeated, and a membranous stricture distal to the external sphincter - also known as Cobb's collar - was diagnosed and incised. After the procedure, the patient was able to urinate with residual volumes ranging from 40-50 ml. However, two weeks later, residual volumes increased again, and a second cystoscopy was performed. In addition to the open Cobb's collar, a PUV was detected, and both were incised with a cold hooked knife.</p><p><strong>Conclusions: </strong>The diagnosis is difficult to make unless the urologist is aware of and actively looks for these rare congenital anomalies of the urethra, which present with variable clinical manifestations and degrees of obstruction.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vahudin Zugor, Mustapha Addali, Benjamin Hager, David Kajaia
{"title":"[Operative management of penoscrotal elephantiasis].","authors":"Vahudin Zugor, Mustapha Addali, Benjamin Hager, David Kajaia","doi":"10.1055/a-2442-4858","DOIUrl":"https://doi.org/10.1055/a-2442-4858","url":null,"abstract":"<p><p>Enormous oedema of the male genitals, such as penoscrotal elephantiasis, is a very rare condition. It is usually a result of recurrent inflammation, trauma or malignancy, although the main cause is lymphatic filariasis. Furthermore, it is a challenging condition for both patient as well as the attending healthcare team. By elongation of the lymphatic channels, local oedema is initially created. In the further course, through fibrosis and thus deterioration of the lymphatic drainage, recurrent infections with irreversible elephantiac hard swelling and skin changes are evident. Depending upon the clinical stage, conservative or surgical treatment are suggested. Unfortunately, up to date, no evidence-based therapeutic protocol exists. Interdisciplinary cooperation among doctors, physiotherapists with active cooperation of the patient decide the success of the therapeutic outcome.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142779141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aktuelle UrologiePub Date : 2024-12-01Epub Date: 2024-09-05DOI: 10.1055/a-2363-4744
Alexander Fichtner, Daniel Nettersheim, Felix Bremmer
{"title":"[Histopathological analysis of germ cell tumours: aspects to consider].","authors":"Alexander Fichtner, Daniel Nettersheim, Felix Bremmer","doi":"10.1055/a-2363-4744","DOIUrl":"10.1055/a-2363-4744","url":null,"abstract":"<p><p>Germ cell tumours (GCT) are the most common testicular tumours and form a heterogenous group of tumours with different biological behaviour. Based on differences regarding patient age at first manifestation, morphological characteristics and molecular changes, they are divided into three different groups of GCTs (type I-III). For treatment and prognosis, an exact histopathological analysis of an orchiectomy resection specimen is very important, including the specification of all different histological subtypes with their proportional distribution. This article describes the approach of the preparation of a resection specimen and the histopathological analysis of a testicular tumour. In addition, it describes cases in which additional tools like immunohistochemical and molecular analyses are necessary. Furthermore, the current WHO classification of testicular GCT is discussed.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"528-536"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142138995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aktuelle UrologiePub Date : 2024-12-01Epub Date: 2024-12-03DOI: 10.1055/a-2348-7301
{"title":"Kommentar zu: ProstataCa – Extraprostatische Ausdehnung als Risikofaktor erst ab ISUP Grad 2.","authors":"","doi":"10.1055/a-2348-7301","DOIUrl":"https://doi.org/10.1055/a-2348-7301","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"503"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aktuelle UrologiePub Date : 2024-12-01Epub Date: 2024-12-03DOI: 10.1055/a-2321-2237
{"title":"Radikale Zystektomie: Weniger Hernien durch Netz beim Ileum-Conduit?","authors":"","doi":"10.1055/a-2321-2237","DOIUrl":"https://doi.org/10.1055/a-2321-2237","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"492-494"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aktuelle UrologiePub Date : 2024-12-01Epub Date: 2024-12-03DOI: 10.1055/a-2321-2423
{"title":"ProstataCa – Extraprostatische Ausdehnung als Risikofaktor erst ab ISUP Grad 2.","authors":"","doi":"10.1055/a-2321-2423","DOIUrl":"https://doi.org/10.1055/a-2321-2423","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"500"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aktuelle UrologiePub Date : 2024-12-01Epub Date: 2024-12-03DOI: 10.1055/a-2288-2572
Andreas Wiedemann, Barbara Bojack, Claudia Drews, Ruth Kirschner-Hermanns, Klaus Becher
{"title":"S2k-Leitlinie „Harninkontinenz bei geriatrischen Patienten“ – Teil 3: Operative Therapie der Harninkontinenz.","authors":"Andreas Wiedemann, Barbara Bojack, Claudia Drews, Ruth Kirschner-Hermanns, Klaus Becher","doi":"10.1055/a-2288-2572","DOIUrl":"10.1055/a-2288-2572","url":null,"abstract":"","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":"55 6","pages":"549-554"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aktuelle UrologiePub Date : 2024-12-01Epub Date: 2024-08-06DOI: 10.1055/a-2364-4213
Christoph Oing, Marcus Hentrich
{"title":"[Conventional versus high-dose salvage chemotherapy for relapsed testicular germ cell tumours].","authors":"Christoph Oing, Marcus Hentrich","doi":"10.1055/a-2364-4213","DOIUrl":"10.1055/a-2364-4213","url":null,"abstract":"<p><p>Since the introduction of cisplatin-based combination chemotherapy, patients with metastatic germ cell tumours achieve very high cure rates of >80%. Nevertheless, about 30% of patients relapse despite guideline-endorsed first-line treatment. Of these, again about 50% of patients can still achieve cure with platinum-based salvage chemotherapy and eventually post-chemotherapy residual mass resection.Salvage chemotherapy generally involves platinum-based combination chemotherapy, either as conventional dose cisplatin-based combinations again or as high-dose chemotherapy with subsequent autologous stem cell transplantation.To date, high level evidence from randomised trials supporting the use of salvage high-dose chemotherapy for all patients relapsing after first-line treatment remains lacking, but a large international retrospective registry study had shown a 15% overall survival benefit for patients undergoing salvage high-dose chemotherapy.In this article, we summarise the available literature on the different salvage treatment approaches and discuss these in the light of current treatment guideline recommendations for the management of testicular cancer.</p>","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"543-548"},"PeriodicalIF":0.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}