Aktuelle Urologie最新文献

[Clinical, multimodal sonography of the kidneys and urinary tract - Update 2025]. [临床，肾脏和尿路的多模态超声检查-更新2025]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-05-13 DOI: 10.1055/a-2573-7345

Konrad Friedrich Stock, Katharina Hauner

引用次数: 0

[mpMRI of the Urinary Bladder: Significance and Clinical Use]. [膀胱mpMRI：意义及临床应用]

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-05-07 DOI: 10.1055/a-2528-0195

Kristina Tuchenhagen, Tibor Vag, Maximilian Christian Kriegmair

{"title":"[mpMRI of the Urinary Bladder: Significance and Clinical Use].","authors":"Kristina Tuchenhagen, Tibor Vag, Maximilian Christian Kriegmair","doi":"10.1055/a-2528-0195","DOIUrl":"https://doi.org/10.1055/a-2528-0195","url":null,"abstract":"The diagnosis and staging of bladder cancer is challenging. TUR-B and CT diagnostics bear limitations in detecting muscle invasion and perivesical fat invasion. Thus, second TUR-B is required to ensure more reliable pathological staging. The mpMRI of the urinary bladder is a new diagnostic tool in evaluation of tumor muscle invasion. Numerous retrospective and prospective studies indicate high diagnostic accuracy of the mpMRI in this setting. Current meta-analyses show sensitivities of up to 90% with a high specificity of >85%. The \"Vesical Imaging-Reporting and Data System\" (VI-RADS) is a standardized and clinically easy-to-use reporting system for mpMRI of the urinary bladder. The EAU guidelines recommend the mpMRI and the VI-RADS system for local staging of urinary bladder cancer. A recently published consensus statement based on a Delphi conference of 92 international experts favors the use of the mpMRI in various clinical situations. This includes imaging before and after TUR-B when muscle invasion is possible or during neoadjuvant chemotherapy.Based on good evidence, the mpMRI of the bladder emerges as a useful imaging tool in the evaluation of urinary bladder cancer in various clinical scenarios. Availability, costs and limited experience currently stand in the way of widespread use.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Digital health for benign prostate syndrome]. [良性前列腺综合症的数字健康]

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-05-05 DOI: 10.1055/a-2573-7302

Sandra Helen Schönburg

引用次数: 0

[How many MRI sequences are required for prostate cancer detection?] 前列腺癌检测需要多少次MRI序列？］

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-05-05 DOI: 10.1055/a-2523-6010

Fabian Falkenbach, Tim Inderhees, Lars Budäus

{"title":"[How many MRI sequences are required for prostate cancer detection?]","authors":"Fabian Falkenbach, Tim Inderhees, Lars Budäus","doi":"10.1055/a-2523-6010","DOIUrl":"https://doi.org/10.1055/a-2523-6010","url":null,"abstract":"Multiparametric magnetic resonance imaging (mpMRI) is an established imaging modality for prostate cancer. In this context, \"multiparametric\" refers to the combination of anatomical sequences (T1- and T2-weighted) with functional (diffusion-weighted) and contrast-enhanced sequences. Anatomical sequences offer high spatial resolution, while diffusion-weighted imaging (DWI) assesses the movement of water molecules within tissues, providing information on tissue composition. The contrast-enhanced sequence (Dynamic Contrast-Enhanced, DCE) evaluates tissue perfusion to identify potential tumour angiogenesis. This combination of sequences allows a comprehensive assessment of various aspects of prostate tissue. However, growing evidence suggests that not all sequences are always required. For early detection of prostate cancer, MRI without DCE (=biparametric MRI, bpMRI) should be the standard, because it exhibits similar detection rates for clinically significant prostate cancer. In special cases, such as after previous prostate treatments (e.g., after focal therapy), radiological challenges (e.g., hip replacement), or in cases of negative bpMRI findings with persistent suspicion of prostate cancer, adding DCE may be helpful. MRI screening without DCE is safer, less expensive, and reduces gadolinium emissions. The final results from the prospective, multicentre PRIME study (bpMRI vs. mpMRI before biopsy) are still pending and will further clarify the role of DCE in early detection.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Bladder sparing options for muscle invasive high risk bladder cancer]. [肌肉浸润性高风险膀胱癌的膀胱保留选择]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-05-05 DOI: 10.1055/a-2586-5554

Oliver Hahn, Hubert Kübler

引用次数: 0

[Thrombophlebitis of the superficial dorsal penile vein following a long-haul flight: a case report of penile Mondor's disease without classical risk factors]. [长途飞行后阴茎浅背静脉血栓性静脉炎：无典型危险因素的阴茎蒙多氏病1例报告]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-04-29 DOI: 10.1055/a-2578-3978

Julio Rodas Garzaro, Mirigbal Mirizada, Johannes Moersler, Matthias May, Christian Gilfrich, Anton Kravchuk

{"title":"[Thrombophlebitis of the superficial dorsal penile vein following a long-haul flight: a case report of penile Mondor's disease without classical risk factors].","authors":"Julio Rodas Garzaro, Mirigbal Mirizada, Johannes Moersler, Matthias May, Christian Gilfrich, Anton Kravchuk","doi":"10.1055/a-2578-3978","DOIUrl":"https://doi.org/10.1055/a-2578-3978","url":null,"abstract":"Penile Mondor's disease (PMD) is a rare, typically self-limiting superficial thrombophlebitis of the dorsal penile vein. Common risk factors include intensive sexual activity, penile trauma, and coagulation disorders. We report the first documented case of PMD occurring after a long-haul flight associated with prolonged immobilisation. A 29-year-old male patient presented with an acute, painful swelling of the penile shaft following a transatlantic long-haul flight. Clinical examination revealed a cord-like induration along the dorsal penile vein. Doppler ultrasonography demonstrated a 4 cm-long hypoechogenic structure within the superficial dorsal penile vein, with no detectable venous flow signals in this region. Subsequent magnetic resonance imaging ruled out involvement of the deep penile vein, the external pudendal veins, and the pelvic veins. Conservative management with nonsteroidal anti-inflammatory drugs, topical heparin ointment application, and anticoagulation with low-molecular-weight heparin - later transitioned to an oral factor Xa inhibitor - resulted in complete remission within four weeks. This case underscores the importance of early diagnosis and conservative management of PMD. Prolonged immobilisation should be recognised as a potential risk factor. Prophylactic administration of low molecular weight heparin prior to long-haul flights may be considered in at-risk patients.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Ex-vivo Comparative Study on the Morcellation Efficiency of Different Morcellators]. [不同粉碎器粉碎效率的离体比较研究]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-04-23 DOI: 10.1055/a-2560-3827

Benedikt Becker, Christopher Netsch, Andreas J Gross, Clemens Rosenbaum, Friedrich Otto Hartung, Simon Filmar, Sophia Hook

{"title":"[Ex-vivo Comparative Study on the Morcellation Efficiency of Different Morcellators].","authors":"Benedikt Becker, Christopher Netsch, Andreas J Gross, Clemens Rosenbaum, Friedrich Otto Hartung, Simon Filmar, Sophia Hook","doi":"10.1055/a-2560-3827","DOIUrl":"https://doi.org/10.1055/a-2560-3827","url":null,"abstract":"Anatomical enucleation of the prostate (AEEP) is an established treatment option for benign prostatic hyperplasia (BPH), regardless of prostate size. While advancements in laser technology have significantly improved the enucleation phase, the morcellation process has remained relatively unchanged, with limited innovations in morcellation devices. This study aimed to compare the efficiency of two morcellators in an ex-vivo model: the Piranha morcellator (Richard Wolf GmbH, Knittlingen) and a newly introduced, yet-to-be-commercialized device, the ActiveCut morcellator (Active Fiber Systems GmbH, Jena).The two morcellators were tested in a newly developed ex-vivo model. In both groups, reusable blades were tested ten times at comparable speed settings. For each trial, 60 grams of raw bovine heart tissue were morcellated. The efficiency of the morcellation was then analyzed. Primary endpoints included morcellation efficiency (g/min) and an evaluation of blade deterioration over repeated use. The mean values of continuous variables were compared using a t-test with standard deviation.A total of ten consecutive morcellation trials were conducted with each device. The ActiveCut demonstrated higher morcellation rates at 12.43 g/min, compared to 7.09 g/min with the Piranha morcellator (p<0.05). However, the ActiveCut showed a decline in efficiency over ten trials. In two cases, tissue had to be manually removed from the blade coupling during morcellation, whereas the Piranha morcellator maintained consistent performance without malfunctions.In this ex-vivo study, comparing the ActiveCut and Piranha morcellators, the ActiveCut exhibited higher morcellation efficiency. However, as the ActiveCut has not yet undergone clinical testing, future clinical studies are necessary to assess its safety and potential malfunctions before clinical implementation.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":""},"PeriodicalIF":0.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Gender-/Sex-Specific Differences in Clinical Trials in Uro-Oncology]. [泌尿肿瘤临床试验中性别/性别特异性差异]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI: 10.1055/a-2510-9757

Marie Christine Roesch, Lea Sophie Lütje, Nils Gilbert, Axel Stuart Merseburger, Daniar Osmonov

引用次数: 0

Kommentar. .评论

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2463-1747

引用次数: 0

Die Zukunft der geschlechtsspezifischen Urologie – Wissenschaftliche Evidenz, Medizin und Gesellschaft. 性别泌尿学的未来：科学证据，医学和社会。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-04-01 Epub Date: 2025-04-03 DOI: 10.1055/a-2467-7721

Shahrokh F Shariat, Robert J Schulz

引用次数: 0