Aktuelle Urologie最新文献

[Closure of a prostatocutaneous urinary fistula while preserving sexual function using a perineal approach with Gracilis flap interposition]. [会阴入路加股薄肌瓣介入术在保留性功能的同时闭合前列腺皮肤尿瘘]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2023-12-04 DOI: 10.1055/a-2201-6302

Mathias Reichert, Adam Stepniewski, Marian Grade, Gunther Felmerer, Lutz Trojan, Mirjam Naomi Mohr

引用次数: 0

Gynäkologische Urologie: Urethralkarunkel, Urethralprolaps und Urethradivertikel. 妇科泌尿科：尿道肿块、尿道乳房和尿道放射状突起。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1055/a-2531-5190

Patrick de Geeter

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Kommentar. .评论

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1055/a-2589-8131

引用次数: 0

[Treatment of high-risk upper tract urothelial carcinoma]. 高危上尿路上皮癌的治疗。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-02-12 DOI: 10.1055/a-2504-4215

Yanchun Ma, Friedemann Zengerling

{"title":"[Treatment of high-risk upper tract urothelial carcinoma].","authors":"Yanchun Ma, Friedemann Zengerling","doi":"10.1055/a-2504-4215","DOIUrl":"10.1055/a-2504-4215","url":null,"abstract":"Upper tract urothelial carcinoma (UTUC) is a rare malignancy that is frequently diagnosed at an advanced stage. The diagnostic methods include CT urography, cytology of the upper urinary tract, and ureterorenoscopy (URS). Treatment decisions are guided by risk stratification into low- and high-risk UTUC. In cases of high-risk UTUC, radical nephroureterectomy with bladder cuff excision is considered the surgical gold standard. However, organ-sparing procedures may also be considered in selected cases. Due to the significant reduction in kidney function following RNU and recent prospective data showing favourable radiological and pathological remission rates, the importance of neoadjuvant chemotherapy is being increasingly discussed. For tumours classified as pT2 to pT4 or those with positive lymph node involvement (pN+), adjuvant platinum-based combination chemotherapy is recommended, provided that neoadjuvant chemotherapy has not already been administered. Adjuvant immunotherapy with nivolumab demonstrated no significant therapeutic benefit in the UTUC cohort compared with its use for the treatment of bladder cancer. It should only be considered for patients with tumours ≥pT3 and/or pN+ (or≥ypT2 and/or ypN+ after neoadjuvant chemotherapy) who are either ineligible for or decline platinum-based combination chemotherapy.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"334-339"},"PeriodicalIF":0.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Bladder sparing options for muscle invasive high risk bladder cancer]. [肌肉浸润性高风险膀胱癌的膀胱保留选择]。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-05-05 DOI: 10.1055/a-2586-5554

Oliver Hahn, Hubert Kübler

引用次数: 0

Asymptomatische Bakteriurie vor urologischen Eingriffen. 泌尿外科手术前的无症状细菌学。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1055/a-2438-3793

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IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1055/a-2553-1247

引用次数: 0

Role of the Triglyceride-Glucose Index as a Predictor of Therapeutic Response to Tadalafil in Patients With Erectile Dysfunction. 预测勃起功能障碍患者对他达拉非治疗反应的甘油三酯-葡萄糖指数的作用

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2024-07-24 DOI: 10.1055/a-2354-3573

Ufuk Caglar, Oguzhan Yildiz, Resit Yusuf, Huseyin Burak Yazili, Abdullah Esmeray, Omer Sarilar, Faruk Ozgor

{"title":"Role of the Triglyceride-Glucose Index as a Predictor of Therapeutic Response to Tadalafil in Patients With Erectile Dysfunction.","authors":"Ufuk Caglar, Oguzhan Yildiz, Resit Yusuf, Huseyin Burak Yazili, Abdullah Esmeray, Omer Sarilar, Faruk Ozgor","doi":"10.1055/a-2354-3573","DOIUrl":"10.1055/a-2354-3573","url":null,"abstract":"The triglyceride-glucose (TyG) index is an easily calculable indicator of endothelial dysfunction. We aimed to evaluate the effect of the TyG index on treatment response in patients using tadalafil for the treatment of erectile dysfunction (ED).The data of patients who used tadalafil for ED in our urology clinic between January 2018 and January 2023 were reviewed. The patients completed the 5-item International Index of Erectile Function (IIEF-5) questionnaire before treatment and in the 3rd month of treatment. Response to tadalafil treatment was accepted as an increase in IIEF category. Patients were divided into 2 groups according to treatment response. Factors affecting response to treatment were evaluated with a multivariate analysis.Of the 134 patients included in the study, 99 (73.3%) responded to tadalafil treatment. Mean age and body mass index (BMI) of the patient group responding to treatment were significantly lower than in the untreated group. The rates of diabetes mellitus (DM) and metabolic syndrome (MetS) were significantly lower in the group responding to treatment. Fasting glucose, triglyceride and total cholesterol values were significantly lower in the group responding to treatment than in the treatment-resistant group. The TyG index was 130.0 (102.0-180.0) in the group responding to treatment and 245.0 (182.0-320.0) in the treatment-resistant group (p=0.001). In the multivariate analysis, age, BMI, DM, MetS, and TyG index were affecting treatment response.A high TyG index negatively affects the response to treatment in patients using tadalafil for ED. In addition, age, BMI, presence of DM and MetS are other factors affecting the response to treatment.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"349-353"},"PeriodicalIF":0.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141756546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of 12/14F Ureteral Access Sheath in Flexible Ureteroscopy for Moderate Nephrolithiasis. 12/14F输尿管通路鞘在软性输尿管镜治疗中度肾结石中的作用。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2023-03-14 DOI: 10.1055/a-2024-0359

Tomasz Ozimek, Pauline Dellas, Benedikt Becker, Arkadiusz Miernik, Marie Christine Roesch, Axel Stuart Merseburger, Mario Wolfgang Kramer, Judith Riccarda Wießmeyer

{"title":"The Role of 12/14F Ureteral Access Sheath in Flexible Ureteroscopy for Moderate Nephrolithiasis.","authors":"Tomasz Ozimek, Pauline Dellas, Benedikt Becker, Arkadiusz Miernik, Marie Christine Roesch, Axel Stuart Merseburger, Mario Wolfgang Kramer, Judith Riccarda Wießmeyer","doi":"10.1055/a-2024-0359","DOIUrl":"10.1055/a-2024-0359","url":null,"abstract":"The aim was a retrospective analysis of 12/14F ureteral access sheath (UAS) usage on perioperative outcomes in patients with moderate nephrolithiasis (MN). MN was defined as a maximum of two unilateral kidney stones with a maximum stone diameter of 6-10 mm.We conducted a monocentric retrospective univariate and multivariate analysis of flexible ureteroscopies (fURS) performed for MN between 01/2014 and 12/2018.A total of 402 fURS were performed in patients with urolithiasis; 112 MN cases underwent further analysis. UAS was successfully applied in 33 MN cases [33/112 (29.46%)]. UAS was inserted regardless of the maximum kidney stone diameter and the presence of multiple kidney stones (p > 0.05). Univariate analysis revealed a prolonged median operation time (UAS: 94 min, non-UAS: 74 min, p = 0.04) and median fluoroscopy time (UAS: 75 s, non-UAS: 57.5 s, p = 0.04) in the UAS cohort. These differences were not confirmed on multivariate logistic regression.UAS was not associated with better stone-free rates in either the univariate or multivariate analysis (UAS: 26/33, non-UAS: 61/79, p = 1.0) nor with the occurrence of Clavien-Dindo ≥2 complications (UAS: 3/33, non-UAS: 9/79, p = 0.98) or median length of hospital stay (UAS: 2 days, non-UAS: 2 days, p = 0.169).We identified no statistical benefits from the usage of 12/14F UAS for MN. As no relevant UAS-associated complications were documented, both strategies (with and without UAS) are feasible.","PeriodicalId":7513,"journal":{"name":"Aktuelle Urologie","volume":" ","pages":"354-360"},"PeriodicalIF":0.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9169408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adjuvante Instillationstherapie des intermediate-risk NMIBC. 中等风险NMIBC辅助注射治疗。

IF 0.3 4区医学

Aktuelle Urologie Pub Date : 2025-08-01 Epub Date: 2025-07-22 DOI: 10.1055/a-2517-3242

引用次数: 0