Surgery open science最新文献

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A retrospective study assessing RefluxStop surgery for gastroesophageal reflux disease: Clinical outcomes in 79 patients from Germany 一项评估RefluxStop手术治疗胃食管反流病的回顾性研究:来自德国的79例患者的临床结果
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2024.12.003
Thorsten Lehmann MD, Mantas Šimkus MD, Christoph Oehler MD
{"title":"A retrospective study assessing RefluxStop surgery for gastroesophageal reflux disease: Clinical outcomes in 79 patients from Germany","authors":"Thorsten Lehmann MD,&nbsp;Mantas Šimkus MD,&nbsp;Christoph Oehler MD","doi":"10.1016/j.sopen.2024.12.003","DOIUrl":"10.1016/j.sopen.2024.12.003","url":null,"abstract":"<div><h3>Background</h3><div>This study reports outcomes of the RefluxStop procedure treating gastroesophageal reflux disease (GERD) in clinical practice at a high-volume regional hospital in Germany.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on 79 patients with chronic GERD that underwent the RefluxStop procedure, comprising high mediastinal dissection, loose cruroplasty, esophagogastroplication between vagal trunks, and fundus invagination of the RefluxStop implant. The primary outcome was GERD Health-Related Quality-of-Life (GERD-HRQL) score and improvement from baseline. Secondary outcomes included proton pump inhibitor (PPI) use and intra- and postoperative complications, including dysphagia, esophageal dilatation, and reoperation.</div></div><div><h3>Results</h3><div>Baseline characteristics (<em>n</em> = 79) included large hiatal hernia &gt;3 cm (32.4 %) and previous antireflux surgery (20.3 %). At mean (SD) follow-up of 11 (4.4) months ranging from 4 to 19 months, the median (IQR) and mean (SD) improvements in GERD-HRQL score were 100 % (90.2–100 %) and 92.4 % (13.9 %) from baseline, respectively. Significant reduction in PPI use was observed from a baseline of 94.9 % to 2.5 % at follow-up. All cases of preoperative dysphagia (7.6 %) completely resolved. New-onset, mild dysphagia occurred in one subject (1.3 %) at final follow-up. One subject (1.3 %) experienced asymptomatic device migration into the stomach, likely due to surgical technique with a much too tight invagination, with subsequent conversion to Toupet fundoplication.</div></div><div><h3>Conclusion</h3><div>Analysis of this cohort that underwent RefluxStop surgery indicates excellent safety and effectiveness over this short-term follow-up. Significant improvements in quality of life and PPI use were observed in a population where half had either large hiatal hernia &gt;3 cm or reoperation for previously failed antireflux surgery, a demographic with usually much higher complication rates.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 9-15"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical procedures and techniques in robot-assisted retrograde para-aortic lymphadenectomy
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2024.12.008
Xinyou Wang, Jing Na, Ya Li, Shichao Han, Jun Wang
{"title":"Surgical procedures and techniques in robot-assisted retrograde para-aortic lymphadenectomy","authors":"Xinyou Wang,&nbsp;Jing Na,&nbsp;Ya Li,&nbsp;Shichao Han,&nbsp;Jun Wang","doi":"10.1016/j.sopen.2024.12.008","DOIUrl":"10.1016/j.sopen.2024.12.008","url":null,"abstract":"<div><h3>Background</h3><div>To study the robotic-assisted abdominal aorta lymphadenectomy at the level of the left renal vein, aimed at standardizing and optimizing the surgical procedure.</div></div><div><h3>Methods</h3><div>All surgical procedures are guided by the theory of membrane anatomy, operating within the intermembrane spaces of embryonic compartments.</div></div><div><h3>Results</h3><div>Using robotic assistance in an inverted position to perform lymphadenectomy of the abdominal aorta at the level of the left renal vein enables safe and reliable lymph node removal, combined with the concept of membrane anatomy, not only minimizes surgical bleeding but also helps reduce complications, such as vascular and intestinal injuries.</div></div><div><h3>Conclusion</h3><div>Utilizing robotics to perform lymphadenectomy of the abdominal aorta at the level of the left renal vein can achieve a more meticulous and refined surgical outcome. Precise surgical techniques contribute to standardizing and optimizing surgical procedures, thereby facilitating the learning process.</div></div><div><h3>Trial registration</h3><div>No trial involve.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 35-41"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143101169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The succession of One Day Surgery with Breast Cancer Home Recovery Program by the National Cancer Institute (ODS BHR NCI) during the COVID-19 pandemic in Thailand 泰国国家癌症研究所(ODS BHR NCI)在2019冠状病毒病(COVID-19)大流行期间连续实施“乳腺癌家庭康复一天手术”计划。
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2024.12.001
Chayanoot Rattadilok , Napaphat Poprom , Vipavee Niyomnaitham , Oradee Phadhana-anake , Jirawadee Ruamjaroenchai , Napat Saigosoom , Wimonporn Papathe , Suttida Thuranutch , Araya Chanwet
{"title":"The succession of One Day Surgery with Breast Cancer Home Recovery Program by the National Cancer Institute (ODS BHR NCI) during the COVID-19 pandemic in Thailand","authors":"Chayanoot Rattadilok ,&nbsp;Napaphat Poprom ,&nbsp;Vipavee Niyomnaitham ,&nbsp;Oradee Phadhana-anake ,&nbsp;Jirawadee Ruamjaroenchai ,&nbsp;Napat Saigosoom ,&nbsp;Wimonporn Papathe ,&nbsp;Suttida Thuranutch ,&nbsp;Araya Chanwet","doi":"10.1016/j.sopen.2024.12.001","DOIUrl":"10.1016/j.sopen.2024.12.001","url":null,"abstract":"<div><h3>Background</h3><div>Breast cancer is the most common cancer among women. In response to the need to hospital stays and minimize waiting time for surgery, particularly during the COVID-19 pandemic, the National Cancer Institute developed the One Day Surgery with Breast cancer Home Recovery program (ODS BHR NCI). The aim of study is to assess the success rate of breast cancer surgeries conducted through this program and to evaluate the incidence of complications.</div></div><div><h3>Method</h3><div>The cohort study includes all breast cancer patients who underwent surgery through the ODS BHR NCI program between August 2021 to November 2023. Eligible participants were under 70 years of age. The patients received comprehensive care and education from a multidisciplinary team, adhering to the program's guidelines. Their postoperative outcomes were monitored on the 1<sup>st</sup>, 3<sup>rd</sup>, and 5<sup>th</sup> days following discharge.</div></div><div><h3>Result</h3><div>A total of 206 patients participated in the ODS BHR NCI program during the COVID-19 pandemic in Thailand. The mean age and BMI were 54.21 ± 9.74 years and 24.18 ± 4.02, respectively. The success rate was 99.02 %, with only one case involving a serious complication. Minor complications were reported in 20 cases, including anesthesia-related issues and minor surgical complications. Notably, no patients were diagnosed with COVID-19 following their surgery.</div></div><div><h3>Conclusion</h3><div>Breast cancer surgeries performed under the ODS BHR NCI program achieved a high success rate. The development of pre-, intra-, and post-operative care protocols, alongside comprehensive patient education, has potential to reduce complications and provide an effective model for extending systemic care to a wider range of patients.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11730564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Board Page
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/S2589-8450(25)00007-7
{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2589-8450(25)00007-7","DOIUrl":"10.1016/S2589-8450(25)00007-7","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Page i"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NIH funding for the pediatric surgeon-scientist: An analysis of current trends
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2024.12.005
Colton D. Wayne MD , Zachary Dumbauld BS , Ethan Mills BS , Diana L. Farmer MD , Gail E. Besner MD
{"title":"NIH funding for the pediatric surgeon-scientist: An analysis of current trends","authors":"Colton D. Wayne MD ,&nbsp;Zachary Dumbauld BS ,&nbsp;Ethan Mills BS ,&nbsp;Diana L. Farmer MD ,&nbsp;Gail E. Besner MD","doi":"10.1016/j.sopen.2024.12.005","DOIUrl":"10.1016/j.sopen.2024.12.005","url":null,"abstract":"<div><h3>Background/purpose</h3><div>Previous studies highlighted the success of pediatric surgeons in obtaining NIH funding. Given increasing clinical demands, we sought to analyze the current state of NIH funding for pediatric surgeon-scientists.</div></div><div><h3>Methods</h3><div>APSA membership in August 2023 was filtered for Regular/Associate members and referenced through NIH RePORTER. Data included history of prior/active NIH funding, award type/institute, and funding pathways. Demographics collected included level of professorship, post-graduate degrees, and gender. Academic productivity was assessed by PubMed publications. In addition, a survey was distributed to Regular/Associate APSA members.</div></div><div><h3>Results</h3><div>1079 APSA Regular/Associate members were identified. <u>Total (previous/current) funding</u>: 149 (13.8 %) surgeons had previous/current NIH funding, 145 with complete funding information. There were 371 previous/current grants totaling $387,148,625. 31.7 % of funded surgeons held Chair/Chief positions, 77.9 % were male, and 84.1 % had M.D. degree only. 282 (76.0 %) grants were independent, and 42 (11.3 %) were mentored. 100 (69.0 %) funded surgeons obtained independent investigator awards, 33 (22.8 %) with and 67 (46.2 %) without prior training/mentored grants. <u>Current funding</u>: 52 (4.8 %) surgeons had current NIH funding, with 80 grants totaling $44,232,644. 73 (91.25 %) were independent while 7 (8.75 %) were mentored awards. <u>Academic productivity</u>: Assessment revealed 7197 total publications (range = 0–207, mean = 49.6). <u>Survey:</u> results highlighted perceived challenges and suggested improvements.</div></div><div><h3>Conclusions</h3><div>Compared to a 2013 study by King et al., the percent of funded APSA members has trended downward; however, the number of funded pediatric surgeon-scientists and dollar amount of active NIH funds has increased. Concentrated efforts are needed to support surgical trainees and junior faculty, particularly females, to pursue research and academic pediatric surgery.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 42-49"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age-stratified trends and outcomes of inpatient cholecystectomy for acute cholecystitis in the United States 美国急性胆囊炎住院胆囊切除术的年龄分层趋势和结果
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2024.12.006
Ayesha P. Ng, Joseph E. Hadaya, Sara Sakowitz, Zihan Gao, James Wu, Peyman Benharash
{"title":"Age-stratified trends and outcomes of inpatient cholecystectomy for acute cholecystitis in the United States","authors":"Ayesha P. Ng,&nbsp;Joseph E. Hadaya,&nbsp;Sara Sakowitz,&nbsp;Zihan Gao,&nbsp;James Wu,&nbsp;Peyman Benharash","doi":"10.1016/j.sopen.2024.12.006","DOIUrl":"10.1016/j.sopen.2024.12.006","url":null,"abstract":"<div><h3>Background</h3><div>The elderly population in the United States is rapidly expanding. Older patients over age 65 with acute cholecystitis may face greater perioperative risk compared to younger patients undergoing urgent laparoscopic cholecystectomy. We aimed to characterize trends in utilization and outcomes of inpatient cholecystectomy across the United States stratified by age.</div></div><div><h3>Methods</h3><div>All adults undergoing nonelective, laparoscopic cholecystectomy for acute cholecystitis in the 2012–2021 National Inpatient Sample were identified. Patients were stratified into 4 age groups: 18–49, 50–64, 65–79, and 80+ years. Major adverse events included in-hospital mortality and complications. Multivariable mixed regression was used to evaluate the association of age group with outcomes. Interaction terms were used to analyze differences in risk-adjusted outcomes over time.</div></div><div><h3>Results</h3><div>Of 2,015,699 patients, 41.7 % were aged 18–49, 24.7 % were 50–64, 23.5 % were 65–79, and 10.2 % were 80+ years. Patients aged 65–79 and 80+ had major adverse event rates of 25 % and 34 %, respectively, compared to 5–14 % among younger patients (<em>p</em> &lt; 0.001). After adjustment, patients over age 65 demonstrated nearly 2-fold greater odds of major adverse events (including repair of bile duct injury) and conversion to an open operation compared to younger patients. Patients aged 65–79 comprised an increasing proportion of cholecystectomy cases over time, from 20.0 % in 2012 to 27.5 % in 2021 (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>Outcomes following cholecystectomy for acute cholecystitis among older patients remained significantly worse compared to younger patients over the past decade, with complication rates of 25–34 %. Preoperative counseling about the increased risk of complications following cholecystectomy for older patients is warranted.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 24-29"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanically powered negative pressure dressing reduces surgical site infection after stoma reversal
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2025.01.002
Brian Williams MD , Aubrey Swinford MD , Jordan Martucci MD , Johnny Wang MD , Jordan R. Wlodarczyk MD , Abhinav Gupta MD , Kyle G. Cologne MD , Sarah E. Koller MD , Christine Hsieh MD , Marjun P. Duldulao MD , Joongho Shin MD
{"title":"Mechanically powered negative pressure dressing reduces surgical site infection after stoma reversal","authors":"Brian Williams MD ,&nbsp;Aubrey Swinford MD ,&nbsp;Jordan Martucci MD ,&nbsp;Johnny Wang MD ,&nbsp;Jordan R. Wlodarczyk MD ,&nbsp;Abhinav Gupta MD ,&nbsp;Kyle G. Cologne MD ,&nbsp;Sarah E. Koller MD ,&nbsp;Christine Hsieh MD ,&nbsp;Marjun P. Duldulao MD ,&nbsp;Joongho Shin MD","doi":"10.1016/j.sopen.2025.01.002","DOIUrl":"10.1016/j.sopen.2025.01.002","url":null,"abstract":"<div><h3>Background</h3><div>The use of closed-incision negative pressure wound therapy (ci-NPWT) has been shown to reduce postoperative wound complications and surgical site infections (SSI) after stoma closures. However, use of this approach has not been widely adopted due to high cost of the devices. We present a novel approach to stoma closure in which a self-contained mechanically powered negative pressure dressing (MP-NPD) is applied to primarily closed stoma reversal wounds. We hypothesized that SSI and wound complication rates would be improved compared to traditional stoma closure methods.</div></div><div><h3>Methods</h3><div>This was a prospective investigator-initiated study, in which consecutive patients that underwent stoma reversal with primary stoma wound closure dressed with MP-NPD from May 2021–March 2022. 30-day outcomes from the study group, including surgical site infection, other wound complications, hospital length of stay (LOS), and readmission rates, were then reported.</div></div><div><h3>Results</h3><div>Forty-six patients undergoing local ileostomy or colostomy closure were identified for the study group. Patient demographics and surgical variables were reported. One (2.2 %) patient in the study cohort developed superficial SSI within 30 days of their surgery. Post-op LOS in the study group versus was 4.1 days.</div></div><div><h3>Conclusion</h3><div>Intestinal stoma reversal wounds closed primarily and dressed with the MP-NPD dressings had very low stoma site SSI rates. These results are promising as they pertain to the use of MP-NPD in stoma reversal procedures, however further large prospective RCTs with a matched control group could help better corroborate these findings.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 69-74"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric pilonidal sinus disease: Recurrence rates of different age groups compared to adults
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2025.01.001
Dietrich Doll , Susanne Haas , Ida Kaad Faurschou , Theo Hackmann , Henrike Heitmann , Myriam Braun-Münker , Christina Oetzmann von Sochaczewski
{"title":"Pediatric pilonidal sinus disease: Recurrence rates of different age groups compared to adults","authors":"Dietrich Doll ,&nbsp;Susanne Haas ,&nbsp;Ida Kaad Faurschou ,&nbsp;Theo Hackmann ,&nbsp;Henrike Heitmann ,&nbsp;Myriam Braun-Münker ,&nbsp;Christina Oetzmann von Sochaczewski","doi":"10.1016/j.sopen.2025.01.001","DOIUrl":"10.1016/j.sopen.2025.01.001","url":null,"abstract":"<div><h3>Background</h3><div>Pilonidal sinus disease uncommon in pre-pubertal children. The preferred treatment for pediatric pilonidal sinus patients remains unclear. A growing body of evidence indicates that pediatric pilonidal sinus disease recurs earlier than in adults. We therefore aimed to investigate recurrence rates and the recurrence rates of different surgical approaches.</div></div><div><h3>Methods</h3><div>Some 1217 studies on pilonidal sinus disease, encompassing 134,663 patients were eligible. From them, 5807 pediatric patients were identified. Recurrence rates were compared between adults and children.</div></div><div><h3>Results</h3><div>Pediatric pilonidal sinus patients have a higher 5-year recurrence rate compared to adults (46 % vs. 11.5 %; <em>p</em> &lt; 0.0001). The subgroup of individuals aged 16–18 years appears to experience recurrences 12 months earlier than those below the age of 16. 46.4 % of all pediatric recurrences occur within 5 years.</div></div><div><h3>Conclusions</h3><div>Pediatric pilonidal sinus disease seems to follow a different course in terms of recurrence rate compared to adults with a substantially increased probability of developing recurrent pilonidal sinus disease within the first five years after surgery. Due to the limited evidence base, especially in terms of the surgical approach, additional data is required to gain a more detailed insight into the matter and to improve surgical care for children and adolescents.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 50-56"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The usefulness of presepsin in the early detection of anastomotic leakage after esophagectomy
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2025.01.003
Yoshiro Imai, Ryo Tanaka, Kentaro Matsuo, Hidero Yoshimoto, Mitsuhiro Asakuma, Hideki Tomiyama, Sang-Woong Lee
{"title":"The usefulness of presepsin in the early detection of anastomotic leakage after esophagectomy","authors":"Yoshiro Imai,&nbsp;Ryo Tanaka,&nbsp;Kentaro Matsuo,&nbsp;Hidero Yoshimoto,&nbsp;Mitsuhiro Asakuma,&nbsp;Hideki Tomiyama,&nbsp;Sang-Woong Lee","doi":"10.1016/j.sopen.2025.01.003","DOIUrl":"10.1016/j.sopen.2025.01.003","url":null,"abstract":"<div><h3>Background</h3><div>Anastomotic leakage is a severe complication of esophagectomy, therefore early detection is crucial. Presepsin is a biomarker for early diagnosis of infectious complications. This study assessed presepsin as a biomarker for anastomotic leakage after esophagectomy, compared to C-reactive protein (CRP), white blood cells (WBCs), and neutrophils (Neuts).</div></div><div><h3>Materials and methods</h3><div>This study enrolled 27 patients between October 2019 and December 2020. Levels of presepsin, CRP, WBCs, and Neuts were measured preoperatively and on postoperative days (PODs) 1, 3, 5, and 7.</div></div><div><h3>Results</h3><div>Five patients had anastomotic leakage. Their presepsin levels on POD 7 were significantly higher and tended to be higher on POD 5 (<em>p</em> = 0.04 and <em>p</em> = 0.06, respectively) compared to those without leakage. The area under the curve values for presepsin were highest on PODs 5 and 7 (0.89 and 0.83). Optimal cut-off values for presepsin were 400 pg/mL (sensitivity 100 %; specificity 81.9 %) on POD 5 and similar on POD 7.</div></div><div><h3>Conclusions</h3><div>Presepsin levels on PODs 5 and 7 effectively detect anastomotic leakage after esophagectomy, making it a valuable, simple, non-invasive early detection test.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 75-80"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143100637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes and predictors of unplanned intensive care unit admission for pediatric trauma patients 儿科创伤患者非计划入住重症监护病房的结局和预测因素。
IF 1.4
Surgery open science Pub Date : 2025-01-01 DOI: 10.1016/j.sopen.2024.12.002
Tyler Liang MD , Areg Grigorian MD , Robert Painter MD , James Jeng MD , Theresa Chin MD , Laura F. Goodman MD MPH , Yigit S. Guner MD , Catherine Kuza MD , Jeffry Nahmias MD MHPE
{"title":"Outcomes and predictors of unplanned intensive care unit admission for pediatric trauma patients","authors":"Tyler Liang MD ,&nbsp;Areg Grigorian MD ,&nbsp;Robert Painter MD ,&nbsp;James Jeng MD ,&nbsp;Theresa Chin MD ,&nbsp;Laura F. Goodman MD MPH ,&nbsp;Yigit S. Guner MD ,&nbsp;Catherine Kuza MD ,&nbsp;Jeffry Nahmias MD MHPE","doi":"10.1016/j.sopen.2024.12.002","DOIUrl":"10.1016/j.sopen.2024.12.002","url":null,"abstract":"<div><h3>Background</h3><div>Unplanned intensive care unit (ICU) admission (UIA) is associated with increased morbidity in adult trauma patients, however, is not well studied in pediatric trauma patients (PTPs). We sought to identify predictors of UIA, hypothesizing PTPs with UIA have increased odds of mortality.</div></div><div><h3>Methods</h3><div>The 2017–2019 Trauma Quality Improvement Program (TQIP) database was queried for PTPs ≤16-years-old admitted to non-ICU level of care. Patients with UIA were compared to those without UIA. Multivariable logistic regression analysis was performed to determine predictors of UIA.</div></div><div><h3>Results</h3><div>From 142,160 PTPs, 233 patients had UIA (&lt;1 %). The UIA group had increased acute kidney injury (2.6 % vs 0 %, p &lt; 0.001), length of stay (7 vs 2 days, p &lt; 0.001), and mortality (1.3 % vs. 0.1 %, p &lt; 0.001). Independent predictors of UIA included ureteral, esophageal, and brain injury (all p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>UIA for PTPs is rare but associated with increased complications and death. Significant predictors of UIA include ureteral, esophageal and brain injury.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"23 ","pages":"Pages 30-34"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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