Surgery open science最新文献

{"title":"Comment on the systematic review of TROPIS for anal fistula","authors":"Vipul D. Yagnik MS, FACS , Prema Ram Choudhary","doi":"10.1016/j.sopen.2025.10.002","DOIUrl":"10.1016/j.sopen.2025.10.002","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"30 ","pages":"Pages 51-52"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147397990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative ERCP as proxy for clinically significant retained stones in a population-based cohort?","authors":"Eyvind Liljegren ,&nbsp;Lina Hedestig ,&nbsp;Emma Sverdén ,&nbsp;Johanna Österberg ,&nbsp;Lars Enochsson ,&nbsp;Gabriel Sandblom","doi":"10.1016/j.sopen.2026.01.007","DOIUrl":"10.1016/j.sopen.2026.01.007","url":null,"abstract":"<div><h3>Background</h3><div>The rate of retained common bile duct stones (CBDS) following cholecystectomy can only be estimated if CBDS managed conservatively as well as CBDS treated with endoscopic retrograde cholangiopancreatography (ERCP) are identified. The aim was to explore the rate of retained CBDS and evaluate performance of ERCP as proxy for retained CBDS in a population-based setting.</div></div><div><h3>Methods</h3><div>Data were collected from The Swedish Gallstone Surgery and Endoscopic Retrograde Cholangiopancreatography Register (GallRiks) on patients who underwent cholecystectomy 2015–2020 with suspected CBDS at South General Hospital, Stockholm, Sweden. Medical records were reviewed to identify rate of patients with events raising suspicion of passage of retained CBDS and compare this to the rate of ERCP for retained CBDS.</div></div><div><h3>Results</h3><div>A total of 182 of 386 patients (47.2%) had CBDS on intraoperative cholangiography (IOC). During follow-up, 33 of the 182 presented with retained CBDS according to medical records. Of these, 24 had an ERCP registered in GallRiks with retained CBDS reported, whereas 9 had retained CBDS according to medical records only.</div></div><div><h3>Conclusion</h3><div>Postoperative ERCP found valid as proxy for retained stones following surgery for CBDS and can be a quality measure for management of patients undergoing gallstone surgery with suspicion of CBDS.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"30 ","pages":"Pages 36-40"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2589-8450(26)00012-6","DOIUrl":"10.1016/S2589-8450(26)00012-6","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"30 ","pages":"Page i"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147398478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity surgery improves metabolic dysfunction-associated steatotic liver disease and type 2 diabetes – MRI and biochemical analysis of liver and pancreas","authors":"Dr. med. Hannes Götz Kenngott M.Sc. ,&nbsp;Philipp Anthony Wise ,&nbsp;Yixin Jiang M.Med. ,&nbsp;Dr. med. Amila Cizmic ,&nbsp;Felix Wagner ,&nbsp;Prof. Dr. med. Hans-Ulrich Kauczor ,&nbsp;PD Dr. Dr. med. Adrian T. Billeter ,&nbsp;Prof. Dr. med. Lars Fischer MBA ,&nbsp;PD Dr. med. Johanna Nattenmüller ,&nbsp;Prof. Dr. med. Beat Peter Müller-Stich ,&nbsp;Dr. Med. Rainer Grotelüschen ,&nbsp;Prof. Dr. med. Felix Nickel MME","doi":"10.1016/j.sopen.2025.12.006","DOIUrl":"10.1016/j.sopen.2025.12.006","url":null,"abstract":"<div><h3>Background</h3><div>This study evaluated changes in metabolic dysfunction-associated steatotic liver disease (MASLD), type 2 diabetes mellitus, liver volume, liver/pancreas fat in patients after obesity surgery.</div></div><div><h3>Methods</h3><div>Magnetic Resonance Imaging (MRI) measured liver volume/fat and pancreas fat in 31 patients with laparoscopic sleeve gastrectomy (LSG, <em>N</em> = 20) or Roux-en-Y gastric bypass (RYGB, <em>N</em> = 11) preoperatively and at 3- and 12-month follow-up. Clinical data and blood values were taken concomitantly to calculate Non-alcoholic fatty liver disease (NAFLD) score.</div></div><div><h3>Results</h3><div>The percentage total weight lost (17.5 % ± 5.4 % at 3 months, 28.4 % ± 8.3 % at 12 months) and percentage excess weight lost (40.0 % ± 11.8 % at 3 months, 65.0 % ± 18.8 % at 12 months) were significant. Liver volume decreased from 2378.3 ± 514.5 cm³ to 1928.7 ± 333.5 cm³ at 3 months (<em>p</em> &lt; 0.001) and 1685.0 ± 310.9 cm³ at 12 months (<em>p</em> &lt; 0.001) after surgery. Liver fat percentage decreased from 16.7 % ± 10.3 % to 8.7 % ± 5.4 % at 3 months (p &lt; 0.001) and 5.2 % ± 3.6 % at 12 months (p &lt; 0.001). Pancreatic fat percentage showed a reduction from 14.8 % ± 5.5 % to 10.9 % ± 4.9 % at 3 months (<em>p</em> = 0.007) postoperatively. NAFLD score improved from preoperative measurements to 12 months postoperatively (−0.89 ± 1.54 vs. -1.77 ± 1.25, <em>p</em> &lt; 0.019). Preoperatively, 22 of 31 (71 %) patients had advanced/intermediate scores; 12 months postoperatively only 12 (39 %) remained (<em>p</em> = 0.044). No significant differences between LSG and RYGB were found regarding goal parameters.</div></div><div><h3>Conclusion</h3><div>Obesity surgery reduced liver volume, type 2 diabetes, fat content of liver and pancreas and improved indicators of MASLD. No significant difference in outcome between operation methods could be established.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 43-51"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145978542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of deceased donor acute kidney injury (AKI) on renal transplant outcomes","authors":"Mikhail Nozdrin MBBS ,&nbsp;Maria Irene Bellini PhD ,&nbsp;Maria Selyanina BSc ,&nbsp;Maria Nozdrina BA ,&nbsp;Kavyesh Vivek MBBS ,&nbsp;Simona Mihalikova BSc ,&nbsp;Vassilios Papalois MD","doi":"10.1016/j.sopen.2025.11.001","DOIUrl":"10.1016/j.sopen.2025.11.001","url":null,"abstract":"<div><h3>Aims</h3><div>Donor AKI is a common reason for discarding deceased donor kidneys due to uncertainty regarding transplant outcomes. Our study investigated the effect of AKI in donor kidneys on post-transplantation outcomes.</div></div><div><h3>Methods</h3><div>Medline, Embase, Cochrane and Web of Science were searched. Risk of bias assessment was performed. 2984 studies were identified by the search, 34 met the inclusion criteria. A total of 103,529 kidney transplants were analysed, 97,165 (94 %) with and 6364 (6 %) without donor AKI.</div></div><div><h3>Results</h3><div>There was no significant difference between recipients of grafts from donors with terminal serum creatinine &gt;2.0 mg/dl and &lt; 2.0 mg/dl in 1 year serum creatinine (MD: -0.01, CI: −0.09-0.07, <em>P</em> = 0.84), 1 year patient survival (RR: 0.99, CI: 0.96–1.02, <em>P</em> = 0.52), as well as in 1 year (RR: 1.01, CI: 0.98–1.03, <em>P</em> = 0.61) and 5 year (RR: 0.99, CI: 0.94–1.04, <em>P</em> = 0.63) graft survival. DGF was the only parameter significantly worse in recipients of grafts from donors with terminal serum creatinine &gt;2.0 than to non-AKI recipients (RR: 1.89, CI: 1.64–2.17, <em>P</em> &lt; 0.01). In studies that compared the severity of AKI stage using the AKIN criteria, there was no significant difference in 1 year post-transplantation serum creatinine even between recipients of grafts from the most severe AKI stage (AKIN3) and the non-AKI group (AKIN0) (MD: -0.01, CI:-0.17–0.16, <em>P</em> = 0.92).</div></div><div><h3>Conclusions</h3><div>Donor AKI is associated with a higher incidence of DGF but has no effect on post-transplant patient and graft survival and, based on this analysis, should not be a sole reason for discarding kidneys.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 7-21"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145792285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of adipose-derived stem cell therapy for complex perianal fistulas in Crohn's disease patients: A systematic review","authors":"Mohammed Aldakhil ,&nbsp;Raghad Ibrahim albarrak MBBS ,&nbsp;Jana Abdullah Alomar ,&nbsp;Leena Ibrahim Alnasr ,&nbsp;Rima Mohammed Alassaf ,&nbsp;Nouf khaled Alhumaid","doi":"10.1016/j.sopen.2025.11.002","DOIUrl":"10.1016/j.sopen.2025.11.002","url":null,"abstract":"<div><h3>Background</h3><div>Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) that often leads to the development of complex perianal fistulas, significantly impairing patients' quality of life. Conventional medical and surgical treatments offer limited long-term efficacy, with high recurrence rates and associated complications. Adipose-derived stem cell therapy (ADSCT) has emerged as a promising regenerative therapy due to its anti-inflammatory and tissue-regenerative properties. However, discrepancies in clinical outcomes across studies warrant a systematic evaluation of its efficacy and safety.</div></div><div><h3>Objective</h3><div>This systematic review aims to critically assess the efficacy, safety, and recurrence rates of ADSCT for complex perianal fistulas in Crohn's disease patients, summarizing data from randomized controlled trials and observational studies.</div></div><div><h3>Methods</h3><div>This review included 19 studies published between 2009 and 2024 involving Crohn's disease patients treated with either autologous or allogeneic ADSCT. Extracted data included patient demographics, fistula characteristics, treatment protocols, and clinical outcomes such as fistula closure, partial healing, time to healing, recurrence, and adverse events. Study selection followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and is illustrated in a PRISMA flow diagram. Risk of bias was assessed using the Cochrane Risk of Bias Tool for randomized controlled trials and adapted versions of the Newcastle-Ottawa Scale (NOS) and MINORS criteria for observational studies. Studies were categorized as excellent, good, or fair based on their total quality score.</div></div><div><h3>Results</h3><div>Fistula closure rates ranged from 23.1 % to 91 %, with an overall average of 62.5 %. Partial healing rates varied widely, between 9 % and 93.3 %. Time to healing ranged from 8 to 48 weeks, with an average of 25.3 weeks. Recurrence rates were reported in over half of the studies and reached up to 38.5 %, with a mean recurrence rate of 19.2 %. The majority of adverse events were mild and transient, including local inflammation, discomfort, and minor infections. No serious (Grade 3 or 4) complications were reported. Risk of bias assessment classified one study as excellent, two as good, and two as fair in methodological quality.</div></div><div><h3>Conclusion</h3><div>Adipose-derived stem cell therapy demonstrates promising efficacy and a favorable safety profile for the treatment of complex perianal fistulas in Crohn's disease. While ADSCT may achieve meaningful clinical response and symptom relief in a substantial proportion of patients, variability in outcomes and study designs highlights the need for standardized protocols and long-term follow-up in future trials.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 22-28"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145792284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends, challenges and ethical considerations in pediatric robotic surgery","authors":"Anoush Sardesai Sadat ,&nbsp;Suhaib J.S. Ahmad ,&nbsp;Sjaak Pouwels","doi":"10.1016/j.sopen.2025.12.002","DOIUrl":"10.1016/j.sopen.2025.12.002","url":null,"abstract":"<div><div>Robotic surgery is revolutionizing healthcare by offering unparalleled precision and control in minimally invasive procedures. With the da Vinci system leading this transformation, surgeons can perform complex operations with enhanced accuracy, reduced recovery times, and fewer complications. In this narrative review, we expanding role of robotic surgery in pediatric cases, highlighting its advantages over conventional techniques, such as improved visualization, reduced tremor, and shorter learning curves. However, challenges like high costs, limited instrument availability, and ethical concerns about access and equity persist. We also examine emerging trends, including telesurgery and augmented reality, which promise to further innovate the field. As pediatric robotic surgery continues to evolve, balancing technological advancements with ethical considerations is crucial to ensuring all children benefit from these cutting-edge surgical solutions. Understanding these dynamics will help guide future applications, making robotic surgery not just a tool for select cases but a standard of care that is accessible, efficient, and equitable.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 29-31"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appraisal on the indications, subtypes, and complications of surgically treated thyroid diseases for thyroidologists: A systematic review and meta-analysis in thyroidology","authors":"Ilker Sengul MD, Professor ,&nbsp;Demet Sengul MD, Professor","doi":"10.1016/j.sopen.2025.12.005","DOIUrl":"10.1016/j.sopen.2025.12.005","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 34-35"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the impact of comorbidities on surgical outcomes in laparoscopic gastrectomy","authors":"Saleha Khan ,&nbsp;Aleena Zobairi ,&nbsp;Ibrahim Kutbi ,&nbsp;Nuran Alsobyani ,&nbsp;Hamad Aldobashi ,&nbsp;Zulaihat Galadima ,&nbsp;Ameena Manzoor ,&nbsp;Sjaak Pouwels","doi":"10.1016/j.sopen.2025.12.003","DOIUrl":"10.1016/j.sopen.2025.12.003","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 32-33"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145927091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of psychiatric illness with acute outcomes following emergency general surgery","authors":"Giselle Porter BS ,&nbsp;Sara Sakowitz MD MBA MPH ,&nbsp;Syed Shaheer Ali ,&nbsp;Troy Coaston MSCR ,&nbsp;Konmal Ali ,&nbsp;Amulya Vadlakonda MD ,&nbsp;Zihan Gao MHSc ,&nbsp;Peyman Benharash MD","doi":"10.1016/j.sopen.2025.12.001","DOIUrl":"10.1016/j.sopen.2025.12.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Prior work has linked severe psychiatric illness (SPI) with greater postoperative mortality and complications following several elective operations. However, this relationship has not been defined in the setting of emergency general surgery (EGS).</div></div><div><h3>Methods</h3><div>The 2016–2021 United States Nationwide Readmissions Database was used to identify all non-elective adult EGS hospitalizations performed within 48 h of admission. SPI was defined using ICD-10 codes for bipolar disorder and schizophrenia. Patients with severe psychiatric illness comprised the SPI cohort (others: Non-SPI). Multivariable linear and logistic regression models were developed to evaluate the independent association of severe psychiatric illness with in-hospital mortality, perioperative complications, and costs.</div></div><div><h3>Results</h3><div>Of 2,124,284 EGS patients, 52,130 (2.5 %) were categorized as SPI. On adjusted analysis, SPI was associated with greater odds of in-hospital mortality (Adjusted Odds Ratio [AOR] 1.21; 95 % Confidence Interval [CI]:1.11–1.31), hospitalization costs (+$2304; 95 %CI: +1950, +2658), as well as a 3-fold increase in relative risk of non-home discharge (AOR 3.18, 95 % CI: 3.05–3.31).</div></div><div><h3>Conclusions</h3><div>Among EGS patients, severe psychiatric illness was linked with inferior clinical and financial outcomes. Improved psychiatric screening and care may allow for early intervention and targeted postoperative care, potentially mitigating complications and costs for these vulnerable patients.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"29 ","pages":"Pages 1-6"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145753683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}