Surgery open science最新文献

{"title":"Prolonged allograft survival in liver transplantation","authors":"Yash Kadakia MD ,&nbsp;Andrew D. Shubin MD, PhD ,&nbsp;Malcolm MacConmara MBBCh FACS ,&nbsp;Madhukar S. Patel MD, MBA, ScM ,&nbsp;Jorge A. Sanchez-Vivaldi MD ,&nbsp;Lauren E. Matevish MD ,&nbsp;Steven I. Hanish MD, FACS ,&nbsp;Parsia A. Vagefi MD, FACS ,&nbsp;Christine S. Hwang MD, FACS","doi":"10.1016/j.sopen.2025.03.006","DOIUrl":"10.1016/j.sopen.2025.03.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Donor age has traditionally been considered a factor associated with allograft failure in liver transplantation. We sought to examine the characteristics and outcomes of all liver allografts with a cumulative age of over 80 years within the US to better understand liver senescence.</div></div><div><h3>Methods</h3><div>Using the UNOS STARfile, allografts with a cumulative age (sum of age at transplant plus post-transplant survival) of octogenarian, 90–99 nonagenarian, and 100 years or greater (centurion) were identified from all adult transplant recipients between 1990 and 2022. Donor and recipient data as well as outcomes were analyzed.</div></div><div><h3>Results</h3><div>There were 3437 octogenarian, 622 nonagenarian, and 29 centurion allografts. Donors from allografts with prolonged cumulative age had less diabetes, less alcohol use, and fewer infections compared to all other donors. Recipients had significantly lower MELD scores at the time of transplant and dialysis rates.</div></div><div><h3>Conclusions</h3><div>Careful matching of older donors with lower MELD recipients results in excellent outcomes as evidenced by the presence of prolonged cumulative age livers, demonstrating the resilience of the liver to senescent events in appropriately matched recipients.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"25 ","pages":"Pages 8-13"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143767904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pooled perspectives: Critical considerations for the modern meta-analysis","authors":"Melissa Justo MD,&nbsp;Halil Askin MD,&nbsp;Deep Mehta,&nbsp;Peyman Benharash MD MS","doi":"10.1016/j.sopen.2025.03.005","DOIUrl":"10.1016/j.sopen.2025.03.005","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"25 ","pages":"Pages 5-7"},"PeriodicalIF":1.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of complication rates in transgender top surgery (female to male) between conventional bandages and negative pressure wound therapy – A retrospective analysis","authors":"Carmen Leser ,&nbsp;Georg Dorffner ,&nbsp;Fiona Kabashi ,&nbsp;Christine Deutschmann ,&nbsp;Daniel König ,&nbsp;Zaza Kashibadze ,&nbsp;Selina Ebner ,&nbsp;Daphne Gschwantler-Kaulich","doi":"10.1016/j.sopen.2025.03.003","DOIUrl":"10.1016/j.sopen.2025.03.003","url":null,"abstract":"<div><div>Fifty to 70 % of transgender patients undergo gender-affirming top surgery. In other types of surgeries, the use of negative pressure wound therapy (NPWT) was described as a major point in reducing complications, and we, therefore, examined possible similar effects when using it in gender-affirming top surgery.</div><div>We investigated differences in the complication rates after body contouring surgery with or without the use of NPWT and included 58 female-to-male transgender patients who have been operated on at the Medical University of Vienna between 2017 and 2020 in this retrospective analysis.</div><div>Without NPWT, significantly more patients suffered from wound dehiscence (<em>p</em> = 0.026) and slightly more patients had to undergo postoperative percutaneous drainage due to seroma (<em>p</em> = 0.129). However, patients had significantly less revision surgery because of severe bleeding with the conventional dressing (<em>p</em> = 0.005). The surgical method was another factor influencing the occurrence of wound dehiscence, especially regarding the incision type and the resected volume. Large breasts and the necessity for using a typical mastectomy incision were underlying factors for dehiscence.</div><div>There are fewer complications when using NPWT, especially regarding wound dehiscence in top surgery; however, postsurgery monitoring is required for severe bleeding afterward.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"25 ","pages":"Pages 1-4"},"PeriodicalIF":1.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NIH funding for the pediatric surgeon-scientist: A stable entity, but for how long?","authors":"Troy A. Markel MD, FACS, FAAP","doi":"10.1016/j.sopen.2025.02.008","DOIUrl":"10.1016/j.sopen.2025.02.008","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Pages 72-73"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143577405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the necessity of simultaneous cholecystectomy in patients undergoing liver hydatid cyst surgery","authors":"Hüseyin Fahri Martlı ,&nbsp;Arzu Hazal Aydın ,&nbsp;Eda Şahingöz ,&nbsp;Derviş Duru ,&nbsp;Sadettin Er ,&nbsp;Nesrin Turhan ,&nbsp;Mesut Tez","doi":"10.1016/j.sopen.2025.02.009","DOIUrl":"10.1016/j.sopen.2025.02.009","url":null,"abstract":"<div><h3>Introduction</h3><div>Liver hydatid cysts remain a significant public health issue in Turkey, the Middle East, East Asia, and Russia. Surgical treatments are often employed for certain stages of this disease. However, the necessity of simultaneous cholecystectomy during these procedures remains unclear. Treating symptoms related to subsequent cholelithiasis can become more challenging. This study investigates the necessity of simultaneous cholecystectomy by following patients who underwent hydatid cyst surgery with or without concurrent cholecystectomy.</div></div><div><h3>Materials and methods</h3><div>Patients who underwent surgery for hydatid cysts between 2019 and 2024 at the General Surgery Clinic of Ankara Bilkent City Hospital were retrospectively reviewed. A total of 97 patients were included, with 56 (54.32 %) undergoing cholecystectomy along with hydatid cyst surgery (Group 1) and 41 (45.68 %) not undergoing cholecystectomy (Group 2).</div><div>Preoperative clinical, laboratory, and radiological findings, as well as intraoperative data, morbidity, mortality, and postoperative symptoms, were analyzed.</div></div><div><h3>Results</h3><div>Patients in Group 1 had longer hospital stays, higher blood loss, and significantly higher Clavien-Dindo complication scores. In the postoperative follow-up of Group 2, 8 patients (19.51 %) developed stones or sludge, and 1 patient (2.4 %) developed polyps. Four patients (9.75 %) presented to the emergency department with cholecystitis symptoms. A total of 5 patients (12.19 %), including 4 with symptomatic cholelithiasis (9.7 %) and 1 with gallbladder polyps (2.4 %), underwent elective cholecystectomy. Two (40 %) of these cholecystectomies were performed laparoscopically, while three (60 %) were converted to open cholecystectomy.</div></div><div><h3>Conclusion</h3><div>Simultaneous cholecystectomy during liver hydatid cyst surgery may prevent difficulties associated with treating symptoms related to subsequent cholelithiasis.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Pages 61-65"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A technical note of flex video-assisted anal fistula treatment procedure: Utilizing modified flexible fistuloscope in video-assisted approach for anal fistula laser treatment","authors":"Okkian Wijaya Kotamto ,&nbsp;Tery Nehemia Nugraha Joseph ,&nbsp;Clement Dewanto ,&nbsp;Natalia Maria Christina ,&nbsp;Nadiska Patricia Artha ,&nbsp;Marsja Ruthfanny Hutapea ,&nbsp;Jeremiah H. Wijaya","doi":"10.1016/j.sopen.2025.03.001","DOIUrl":"10.1016/j.sopen.2025.03.001","url":null,"abstract":"<div><div>This study explores an innovative approach for managing complex anal fistulas, known as the flexible video-assisted anal fistula treatment (flex-VAAFT). This technique uses a modified flexible fistuloscope and a laser diode for precise laser ablation. The flexible fistuloscope offers a wider field of view compared to the traditional VAAFT fistuloscope, allowing for better visualization and accurate assessment of the fistula tract's internal anatomy, enabling meticulous debridement and irrigation. We applied the flex-VAAFT approach in seven male patients aged 36 to 66, documenting the external and internal openings, etiology, and fistula type. Seton placement was used in one case, with follow-up periods ranging from 6 to 12 months. Most patients experienced successful healing, with only one recurrence observed. There were no cases of anal incontinence, and the average hospital stay was brief, lasting between 1 and 2 days. The findings suggest that flex-VAAFT is a promising, minimally invasive method for treating anal fistulas, enhancing surgical precision while preserving anal continence.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Pages 80-85"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the dynamics of postoperative steatosis in the regenerating liver: An animal study","authors":"Andrea Lund ,&nbsp;Katrine Holm Andersen ,&nbsp;Kasper Jarlhelt Andersen ,&nbsp;Jakob Kirkegård ,&nbsp;Jens Randel Nyengaard ,&nbsp;Frank Viborg Mortensen","doi":"10.1016/j.sopen.2025.02.005","DOIUrl":"10.1016/j.sopen.2025.02.005","url":null,"abstract":"<div><h3>Introduction</h3><div>The rat model of 70 % partial hepatectomy (PH) is commonly used to investigate liver regeneration processes. The aim of this study was to explore the dynamics of hepatic lipid accumulation and its correlation with the proliferation response during the entire regeneration phase after 70 % PH in rats.</div></div><div><h3>Methods</h3><div>Sixty-four rats underwent 70 % PH and were randomly divided into eight groups for evaluation on post-operative day (POD) 1 to 8. Hepatocyte volume, relative lipid content, and lipid volume per hepatocyte were assessed by stereological analysis.</div><div><strong>Results:</strong> Lipid volume per hepatocyte reached its peak on POD 1 and POD 2, with mean values of 2895 μm³ (95 % CI: 1756–4034 μm³) and 3090 μm³ (95 % CI: 2277–3903 μm³), respectively. A marked decline was observed by POD 4, with a mean of 1323 μm³ (95 % CI: 985–1741 μm³), which continued through POD 5, reaching 619 μm³ (95 % CI: 136–1102 μm³). From POD 5 onwards, lipid volume remained consistently low, with no significant differences detected between POD 5 and POD 8.</div></div><div><h3>Conclusion</h3><div>Lipid accumulation and proliferation peak and decline concurrently, suggesting a strong correlation.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Pages 66-69"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ERAS protocol in colorectal surgery is effective in octogenarians: A retrospective cohort study","authors":"Justin Dourado MD ,&nbsp;Ariel Wolf MD ,&nbsp;Maria Herrera Rodriguez DO ,&nbsp;Shruti Agarwal BS ,&nbsp;Karin Blumofe MD ,&nbsp;Jordan Moseson DO ,&nbsp;Jose Yeguez MD ,&nbsp;Andrew Ross MD ,&nbsp;Avraham Belizon MD","doi":"10.1016/j.sopen.2025.03.004","DOIUrl":"10.1016/j.sopen.2025.03.004","url":null,"abstract":"<div><h3>Purpose</h3><div>Evaluate the effectiveness of implementing an ERAS protocol in octogenarians.</div></div><div><h3>Methods</h3><div>This retrospective cohort study analyzed patients undergoing colorectal surgery under the ERAS protocol at Boca Raton Regional Hospital from December 1, 2019 to October 30, 2021. Patients under the age of 18, undergoing emergency surgery, and with incomplete data were excluded. A <em>p</em> &lt; 0.05 was considered statistically significant and analyses were done using EZR and R software.</div></div><div><h3>Results</h3><div>299 patients met inclusion criteria with 60 (20.1 %) over the age of 80 and 239 (79.9 %) younger than 80. 140 (46.8 %) of the cohort were male. When comparing octogenarians with younger patients there were no differences in compliance with ERAS protocols such as pre-operative medication (<em>p</em> = 1) and oral carbohydrate drink consumption (<em>p</em> = 0.574), oral intake in PACU (<em>p</em> = 0.832), PACU sit and dangle (<em>p</em> = 0.619), or adherence to a narcotic sparing regimen (<em>p</em> = 0.365). Additionally, there were no differences in complications (p = 1), time until bowel function (<em>p</em> = 0.401), or time to first ambulation (<em>p</em> = 0.883). Octogenarians were more likely to have a longer LOS (4.89 v 3.0 days; <em>p</em> = 0.006), disposition requiring either home health care or a skilled nursing facility (SNF) (52.5 % v 28.3 %; <em>p</em> = 0.008), and readmission (42.3 % v 20.8 %; <em>p</em> = 0.042).</div></div><div><h3>Conclusion</h3><div>The ERAS protocol is safe and effective when used in the octogenarian without decreased compliance or increased complications. Increased LOS, care needed on disposition, and readmission are in-line with other published data of all patients and are likely related to increased frailty among this group and not to the addition of the ERAS protocol.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Pages 86-91"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Board Page","authors":"","doi":"10.1016/S2589-8450(25)00023-5","DOIUrl":"10.1016/S2589-8450(25)00023-5","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Page i"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143685177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building an international network of young surgeons across surgical specialties – Introducing the Young Surgeons Publications Committee","authors":"Louisa Bolm ,&nbsp;Martina Nebbia ,&nbsp;Thomas F. Stoop ,&nbsp;Mara R. Goetz ,&nbsp;Lena Conradi ,&nbsp;Nathanael Raschzok ,&nbsp;Hannes Jansson ,&nbsp;Patrik Larsson ,&nbsp;Sarah Gerber ,&nbsp;Jorge Roldàn ,&nbsp;Theodoros Michelakos ,&nbsp;Meike ten Winkel ,&nbsp;Benedict Kinny-Köster ,&nbsp;Ingmar F. Rompen ,&nbsp;Oskar Franklin ,&nbsp;Ioannis A. Ziogas ,&nbsp;Hiroyuki Ishida ,&nbsp;Andrii Khomiak ,&nbsp;Daisuke Hashimoto ,&nbsp;Vincent P. Groot ,&nbsp;Nicholas Joseph Zyromski","doi":"10.1016/j.sopen.2025.02.003","DOIUrl":"10.1016/j.sopen.2025.02.003","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"24 ","pages":"Pages 70-71"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143548573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}