{"title":"Validation of two-stage pancreatojejunostomy after pancreatoduodenectomy for patients with a soft pancreatic texture and assessment of the remnant pancreas texture before second surgery","authors":"Ryosuke Hatta, Yoichi Ishizaki, Jiro Yoshimoto, Kenji Takamori","doi":"10.1016/j.sopen.2026.08.007","DOIUrl":"10.1016/j.sopen.2026.08.007","url":null,"abstract":"<div><h3>Background</h3><div>Two-stage pancreatojejunostomy (PJ) after pancreatoduodenectomy (PD) is one of the methods available for minimizing the possibility of grade C postoperative pancreatic fistula (POPF), especially in patients with a soft pancreatic consistency.</div></div><div><h3>Methods</h3><div>We studied 131 patients with a soft pancreatic texture who underwent initial PD without PJ. The pancreatic tube was exteriorized through the abdominal wall incision. Three months later, we performed PJ, except for four patients died of recurrence. The remaining 127 patients underwent two-stage PJ. To assess the changes in pancreatic consistency after PD, computed tomography (CT) attenuation of the pancreas was measured before PD and compared with that after PD in 36 patients.</div></div><div><h3>Results</h3><div>After initial PD, none of the patients suffered grade C POPF and postoperative mortality was zero. After the second operation, none of the patients suffered grade C POPF. One patient died due to recurrence of cancer. There was no mortality attributable to any adverse effect of POPF. The postoperative mortality rate was 0.7%. At the time of two-stage PJ, surgeons confirmed that texture of the remnant pancreas had changed from soft to hard. CT attenuation of the remnant pancreas before PJ was significantly lower than that of the pancreas body before PD (32.3 ± 10.0 vs. 40.5 ± 8.2, <em>p</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>Two-stage PJ can be considered to minimize likelihood of grade C POPF. The changes in CT attenuation before PD and before PJ provide objective confirmation of a change in pancreatic texture from soft to hard, thus largely accounting for the reduced incidence of fatal POPF.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"33 ","pages":"Pages 108-116"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148958127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery open sciencePub Date : 2026-09-01Epub Date: 2026-09-02DOI: 10.1016/j.sopen.2026.08.004
Irene A. Arias-Romaní, Miguel A. Arce-Huamani
{"title":"Complicated appendicitis and surgical site infection associated with prolonged hospital stay after appendectomy in a Peruvian hospital","authors":"Irene A. Arias-Romaní, Miguel A. Arce-Huamani","doi":"10.1016/j.sopen.2026.08.004","DOIUrl":"10.1016/j.sopen.2026.08.004","url":null,"abstract":"<div><h3>Objective</h3><div>To identify factors associated with prolonged hospital stay after appendectomy for acute appendicitis in a Peruvian public hospital.</div></div><div><h3>Methods</h3><div>We conducted a retrospective case-control study of adults who underwent appendectomy for acute appendicitis at Hospital Jesús Nazareno, Ayacucho, Peru, between January 2021 and December 2024. Cases had a hospital stay of ≥5 days, corresponding to the 75th percentile of the institutional distribution, and controls had a stay of <5 days. From 96 eligible cases and 288 eligible controls, 73 patients from each group were selected by simple random sampling. Crude and adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using logistic regression.</div></div><div><h3>Results</h3><div>Median hospital stay was 6.0 days (IQR, 5.0–9.0) among cases and 2.0 days (IQR, 2.0–3.0) among controls. Complicated appendicitis was more frequent among cases than controls (97.3% vs. 27.4%), as was surgical site infection (38.4% vs. 1.4%). After multivariable adjustment, complicated appendicitis (adjusted OR, 38.62; 95% CI, 7.78–191.82) and surgical site infection (adjusted OR, 9.58; 95% CI, 1.14–80.55) remained associated with prolonged hospital stay.</div></div><div><h3>Conclusion</h3><div>Complicated appendicitis and surgical site infection were associated with prolonged hospital stay after appendectomy. Because the timing of surgical site infection onset was not captured, its temporal relationship with prolonged stay cannot be established. Timely management of complicated appendicitis and adherence to perioperative infection-prevention practices may help reduce prolonged hospitalization.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"33 ","pages":"Pages 100-107"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148958226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery open sciencePub Date : 2026-09-01Epub Date: 2026-08-31DOI: 10.1016/j.sopen.2026.08.006
Maliha Arzumand, Ryan McBride
{"title":"Reconstruction of chronic tibialis anterior tendon rupture using a degradable synthetic matrix: A surgical technique","authors":"Maliha Arzumand, Ryan McBride","doi":"10.1016/j.sopen.2026.08.006","DOIUrl":"10.1016/j.sopen.2026.08.006","url":null,"abstract":"<div><div>Tibialis anterior tendon (TAT) ruptures are uncommon and may occur acutely or present in a chronic, neglected form. Chronic ruptures, generally defined as those present for more than four weeks, are frequently associated with tendon retraction, degenerative stump tissue, and a segmental defect that precludes primary end-to-end repair. Established reconstructive options include tendon transfer, autograft interposition, and allograft interposition, each carrying trade-offs in donor site morbidity, tissue availability, and cost. We describe reconstruction of a chronic insertional TAT rupture in a 68-year-old male using a degradable synthetic polycaprolactone-based polyurethane urea matrix (FlexBand; Artelon, Inc., Marietta, GA, USA) secured to the medial cuneiform with two bone anchors and sutured to a debrided and lengthened proximal tendon stump. At final documented follow-up of 12 weeks, the patient ambulated without foot slap or compensatory gait deviation, with dorsiflexion and plantarflexion clinically symmetric to the contralateral limb and no restriction in activities of daily living. This report describes the technical feasibility of the approach.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"33 ","pages":"Pages 117-122"},"PeriodicalIF":1.6,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148958225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery open sciencePub Date : 2026-06-01Epub Date: 2026-05-21DOI: 10.1016/j.sopen.2026.05.006
Hannah Wavering-Walters MD , Quetzal A. Class PhD , Lopa K. Pandya MD
{"title":"Assessing waste reduction knowledge and practices in the operating room","authors":"Hannah Wavering-Walters MD , Quetzal A. Class PhD , Lopa K. Pandya MD","doi":"10.1016/j.sopen.2026.05.006","DOIUrl":"10.1016/j.sopen.2026.05.006","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"32 ","pages":"Pages 36-37"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148159293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery open sciencePub Date : 2026-06-01Epub Date: 2026-04-24DOI: 10.1016/j.sopen.2026.04.001
Jinyuan Wang , Zejun Yao
{"title":"Comment on “Association of Hospital For-profit Status with Clinical and Financial Outcomes Following Emergency General Surgery”","authors":"Jinyuan Wang , Zejun Yao","doi":"10.1016/j.sopen.2026.04.001","DOIUrl":"10.1016/j.sopen.2026.04.001","url":null,"abstract":"","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"32 ","pages":"Pages 38-39"},"PeriodicalIF":1.7,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148180310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laparoscopic versus open minor liver resections of colorectal cancer liver metastases in a state at war: A prospective cohort study","authors":"Anton Burlaka , Serhii Zemskov , Veronika Rozhkova , Vitaliy Zvirych , Mykhailo Dupyk , Andrii Beznosenko , Volodymyr Bezverkhnyi , Volodymyr Skyba","doi":"10.1016/j.sopen.2026.03.006","DOIUrl":"10.1016/j.sopen.2026.03.006","url":null,"abstract":"<div><h3>Introduction</h3><div>In 2017 the laparoscopic left lateral sectionectomy and minor resections of the anterior liver segments were considered the standard of practice worldwide. However, in 2023 only 5% of liver resections were conducted laparoscopically within the Ukrainian specialized centers.</div></div><div><h3>Aim</h3><div>To investigate whether the laparoscopic minor liver resections (LLR) have better financial, surgical and long-term oncological outcomes compared to open liver resections (OLR) in the two state specialized hospitals in Ukraine<strong>.</strong></div></div><div><h3>Methods</h3><div>Between January 2022 and June 2025, 205 patients with colorectal liver metastases (CLM) received either minor OLR or LLR. Primary end-points were the 30-day morbidity, surgical outcomes. Secondary endpoints were hospital costs and the oncological outcomes.</div></div><div><h3>Results</h3><div>There was a difference in postoperative morbidity between the groups in favor of the LLR – 3.8% (<em>n</em> = 4) vs 11.7% (<em>n</em> = 12) in OLR (<em>p</em> = 0.04). 1.9% (<em>n</em> = 2) in the OLR group had major complications. No mortality was registered in either group. The final sum of costs for treatment of 103 patients in LLR vs 102 patients in OLR was 3.8 M UAH vs 3.5 M UAH, respectively (<em>p</em> = 0.82). The 2-year recurrence-free survival (RFS) was 44% vs 54%, and 19.6 months vs 24.0 months respectively for OLR and LLR groups (<em>p</em> = 0.62)<strong>.</strong></div></div><div><h3>Conclusions</h3><div>The laparoscopic minor liver resections in patients with colorectal cancer liver metastases in state specialized hospitals reduced the recovery period and the postoperative morbidity level with similar oncological outcomes and costs<strong>.</strong></div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"31 ","pages":"Pages 54-59"},"PeriodicalIF":1.7,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147612688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surgery open sciencePub Date : 2026-03-01Epub Date: 2026-01-19DOI: 10.1016/j.sopen.2026.01.002
Axel Bengtsson MD, Roland Andersson MD, PhD, Bodil Andersson MD, PhD, Daniel Ansari MD, PhD
{"title":"Digital quantification of stroma percentage enhances prognostic stratification in pancreatic cancer","authors":"Axel Bengtsson MD, Roland Andersson MD, PhD, Bodil Andersson MD, PhD, Daniel Ansari MD, PhD","doi":"10.1016/j.sopen.2026.01.002","DOIUrl":"10.1016/j.sopen.2026.01.002","url":null,"abstract":"<div><h3>Background</h3><div>Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic stroma, which plays a crucial role in tumor biology and treatment resistance. While the stromal compartment is a defining histopathological feature of PDAC, its prognostic significance remains incompletely understood. This study aimed to quantify the stromal content in PDAC using digital pathology and evaluate its association with patient outcomes.</div></div><div><h3>Methods</h3><div>Tissue microarrays (TMAs) were constructed from resected PDAC specimens (<em>n</em> = 142). Digital analysis of tumor stroma percentage (TSP) was performed on tissue sections labeled with CA19–9. Cases were stratified into low and high TSP groups based on an optimized threshold of 44.2%. Associations between TSP and clinicopathological variables were assessed, and survival outcomes were analyzed using Kaplan-Meier and Cox proportional hazards models.</div></div><div><h3>Results</h3><div>Digital quantification revealed wide intertumoral variability in TSP. A total of 127 (89%) patients were categorized into the high TSP group (>44.2% stroma). A high TSP was significantly associated with anatomic location of the tumor in the head of the pancreas. Patients with high TSP exhibited significantly prolonged overall survival (median: 27.8 months vs 12 months, <em>p</em> < 0.001). In multivariable analysis, high TSP remained an independent predictor of favorable prognosis (HR = 0.26, 95% CI: 0.13–0.52, <em>p</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>A high TSP is independently associated with improved survival in PDAC. These findings challenge traditional views of the stroma as purely tumor-promoting and suggest a potential protective role of the stromal compartment in certain contexts.</div></div>","PeriodicalId":74892,"journal":{"name":"Surgery open science","volume":"30 ","pages":"Pages 8-13"},"PeriodicalIF":1.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}