Sleep advances : a journal of the Sleep Research Society最新文献

{"title":"The effects of deep brain stimulation on sleep: a systematic review and meta-analysis.","authors":"Aryan Wadhwa, Niels Pacheco-Barrios, Shreya Tripathy, Rohan Jha, Millen Wadhwa, Aaron E L Warren, Lan Luo, John D Rolston","doi":"10.1093/sleepadvances/zpae079","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae079","url":null,"abstract":"<p><strong>Background: </strong>Deep brain stimulation (DBS) is a standard treatment for movement disorders, epilepsy, and others, yet its influence on postprocedural sleep quality remains an under-researched topic.</p><p><strong>Study objectives: </strong>We performed a systematic review and meta-analysis of all DBS effects on sleep.</p><p><strong>Methods: </strong>The use of preferred reporting items for systematic reviews and meta-analyses guidelines (PRISMA) was utilized. We extracted demographic data, disease type/duration, DBS target, stimulation laterality (unilateral vs bilateral), follow-up lengths, and sleep pre/post-op measurements with polysomnography or across four standard sleep scales. The Cochrane methodology for evaluating RCTs was employed using the risk of bias assessments, data synthesis, and statistical methods, including forest plots (risk ratio; M-H random effects; 95% CI).</p><p><strong>Results: </strong>Sixty-three studies were included in the overall analysis, representing 3022 patients. In a subgroup meta-analysis of subthalamic nucleus (STN) DBS for Parkinson's disease (PD), patients showed significant sleep improvement at three but not 12 months postoperatively with PDSS, at 12 but not 3 months with Epworth sleep scale, and at 6 months with nonmotor symptom scale. Pittsburgh sleep quality index (PSQI) showed no significant improvement in sleep at any time. Bilateral DBS showed significantly more improvement than unilateral DBS in the PSQI at 6 but not 3 months. Polysomnography showed significant sleep improvement at 1 week but not at 3 or 6 months. Most studies showed no significant sleep improvement for globus pallidus internus, centromedian thalamus, and ventral intermediate nucleus DBS.</p><p><strong>Conclusions: </strong>STN-DBS for PD likely improves sleep; however, significant standardization in sleep scale outcome reporting and follow-up time is needed to effectively determine the target-dependent effects of DBS surgery on sleep.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae079"},"PeriodicalIF":0.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"School start times and their association with rurality in British Columbia, Canada: An environmental scan.","authors":"Elizabeth Keys, Tai-Lin Michon, Kayleigh Boogaart, Amy Beck","doi":"10.1093/sleepadvances/zpae075","DOIUrl":"10.1093/sleepadvances/zpae075","url":null,"abstract":"<p><strong>Study objectives: </strong>Since later school start times are associated with increased sleep duration, our objectives were to identify mean school start times, the proportion of schools that start at 08:30 am or later, and determine if rurality was associated with school start times.</p><p><strong>Methods: </strong>We conducted web searches for start times of 1759 standard schools in British Columbia (BC), Canada. Schools were categorized as elementary, elementary-middle, middle, middle-high, or high school and linked to an Index of Remoteness. We calculated descriptive statistics and used Analysis of Variance to assess for start time differences by grade category. We used Spearman's rank-order correlation to assess if there was a relationship between start time and rurality.</p><p><strong>Results: </strong>We found start times for 1553 (88.2%) of the included schools. The mean start time was 08:40 am (<i>SD</i> = 0:15) and ranged from 07:10 am to 09:45 am. There was a significant effect of grade category on start time, <i>F</i> (5, 1600) = 6.03, <i>p</i> < .001, <i>η</i> ² =.02, 95% CI [.006, .031] such that elementary-middle schools started significantly earlier (<i>M</i> = 08:34 am, <i>SD</i> = 0:17) than other grade categories. Overall, 1388 (86.4%) schools started at 08:30 am or later. Rurality was significantly correlated with school start time (<i>r</i> = -.198), such that more rural schools started earlier.</p><p><strong>Conclusions: </strong>For the most part, school start times in BC meet recommendations that support childhood and adolescent sleep. Future research is needed to understand factors that promote the successful implementation of delayed school start times.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae075"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric comorbidity in Danish patients with narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia: a case-control study.","authors":"Niels Christian Haubjerg Østerby, Lone Baandrup, Poul Jørgen Jennum","doi":"10.1093/sleepadvances/zpae073","DOIUrl":"10.1093/sleepadvances/zpae073","url":null,"abstract":"<p><strong>Study objectives: </strong>To examine the difference in psychiatric comorbidity of Danish patients with Narcolepsy type 1 (NT1), Narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).</p><p><strong>Methods: </strong>Polysomnography (PSG), Multiple Sleep Latency Test (MSLT), and lumbar puncture were performed on 505 patients referred to a sleep clinic for diagnostic evaluation of hypersomnia. Diagnosis, clinical characteristics, electrophysiologic data, and cerebrospinal fluid hypocretin-1 (Csf-Hcrt-1) results were retrieved. Subsequently, the patients were identified in the Danish national health registers to collect information on psychiatric diagnoses and psychotropic medication use 10 years before the sleep disorder diagnosis. The prevalence of psychiatric comorbidities per hypersomnia group was compared to a 1:4 general population control group matched on age, gender, and educational level.</p><p><strong>Results: </strong>A diagnosis of NT2 and IH was significantly associated with total psychiatric comorbidity compared to the matched controls but not NT1 (NT1: OR = 1.5; NT2: OR = 6.1; IH: OR = 5.2). NT1 was not significantly associated with any psychiatric disorder. NT2 was significantly associated with schizophrenia spectrum disorders (OR = 8.5), mood disorders (OR = 6.7), neurotic disorders (OR = 3.8), personality disorders (OR = 3.1), and behavioral and emotional disorders (OR = 4.3). IH was significantly associated with schizophrenia spectrum disorders (OR = 3.3), mood disorders (OR = 5.9), neurotic disorders (OR = 3.0), and behavioral and emotional disorders (OR = 4.0).</p><p><strong>Conclusions: </strong>NT2 and IH had a close relationship to psychiatric disorders before diagnosis of their sleep disorder, while NT1 did not. This supports previous studies finding higher rates of psychiatric illness in patients with hypersomnia; however, it highlights the similarity between NT2 and IH. We believe this link to psychiatric disorders could play a role in the pathophysiology. Future studies evaluating the relation between hypersomnias of central origin and psychiatric diseases should include hypersomnia subclassifications to further the understanding of the differences in these disorders.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae073"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11489886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Infantgram?\" recruitment of infants to a clinical sleep study via social media.","authors":"Cathal O'Connor, Hannah O'Leary, Deirdre Murray, Geraldine B Boylan","doi":"10.1093/sleepadvances/zpae063","DOIUrl":"10.1093/sleepadvances/zpae063","url":null,"abstract":"<p><strong>Study objectives: </strong>This study aimed to outline the strategy and outcomes of a study team in recruiting participants for an infant sleep study via social media during the COVID-19 pandemic, to assess the feasibility of recruitment via social media, and to quantitatively and qualitatively explore parental satisfaction and perceptions of recruitment via social media.</p><p><strong>Methods: </strong>The assessing sleep in infants with early-onset atopic dermatitis by longitudinal evaluation (SPINDLE) study recruited infants with and without atopic dermatitis for a longitudinal study assessing sleep. Infants were recruited via social media and their parents were interviewed to explore their experience of recruitment via social media.</p><p><strong>Results: </strong>In total, 57 controls and 33 cases were recruited. Of the 45 controls recruited via social media, 43 (95.6%) were recruited via Instagram and 2 (4.4%) were recruited via Twitter. Of the seven cases recruited via social media, 6 (85.7%) were recruited via Facebook (via sharing of Instagram posts by third parties on Facebook) and 1 (14.3%) was recruited via Instagram. All (100%, <i>n</i> = 28) mothers recruited via social media who completed the full study were satisfied with this approach to recruitment. Specific reasons why mothers reported engaging following exposure to the social media posts included the benefit of additional health checks for their baby, the benefit to scientific advancement, and the opportunity for a stimulating outing following the COVID-19 lockdowns.</p><p><strong>Conclusions: </strong>Our experience highlights parents' acceptance of recruitment via social media, the optimization of time and financial resources, and the benefit of using internet-based recruitment during a pandemic.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae063"},"PeriodicalIF":0.0,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11448331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CARDIA sleep ancillary study: study design and methods.","authors":"Kristen L Knutson, Kathryn J Reid, Sunaina Karanth, Nathan Kim, Sabra M Abbott, Shaina J Alexandria, Katharine Harrington, S Justin Thomas, Cora E Lewis, Pamela J Schreiner, Mercedes R Carnethon","doi":"10.1093/sleepadvances/zpae071","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae071","url":null,"abstract":"<p><p>Sleep and circadian disturbances are common and are experienced more often by Black compared to White individuals. We conducted an observational study of sleep that was ancillary to an ongoing cohort study, Coronary Artery Disease in Young Adults (CARDIA). The goal of the ancillary study will be to examine potential determinants of sleep/circadian disparities between Black and White adults in future analyses. Herein we describe the study design and methodology. Our ancillary study coincided with the Year 35 examination of the CARDIA study and was conducted in two phases (due to the SARS-COV-2 pandemic). Phase 1 involved only questionnaires to assess chronotype, restless legs syndrome, and the household sleep environment. Phase 2 involved three additional questionnaires to assess sleep quality, daytime sleepiness and insomnia symptoms, as well as two sleep devices. Participants wore a wrist activity monitor to assess sleep-wake patterns and light levels for 7 days and a home sleep apnea test for 1 night. A subset also had devices objectively record light, temperature, and sound levels in their bedrooms for 7 days. Sample sizes ranged based on assessment from 2200 to 2400, completing Phase 1 questionnaires, 899 with valid wrist actigraphy data, and 619 with a valid sleep apnea test. The data will be part of the full CARDIA dataset, which is available to researchers.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae071"},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated prevalence of obstructive sleep apnea by occupation and industry in England: a descriptive study.","authors":"Ryohei Kinoshita, Jennifer K Quint, Constantinos Kallis, Michael I Polkey","doi":"10.1093/sleepadvances/zpae069","DOIUrl":"10.1093/sleepadvances/zpae069","url":null,"abstract":"<p><strong>Study objectives: </strong>Obstructive sleep apnea (OSA) can induce excessive sleepiness, causing work-related injuries and low productivity. Most individuals with OSA in the United Kingdom are undiagnosed, and thus, theoretically, workplace screening, might by identifying these individuals improve both their individual health and overall productivity. However, the prevalence of OSA in different workplaces is unclear. This study aimed to estimate the prevalence of OSA by industries and occupations in England.</p><p><strong>Methods: </strong>The Health Survey for England 2019 dataset was combined with Sleep Heart Health Study dataset. We applied multiple imputation for the combined dataset to estimate OSA in the English population aged 40-64. We estimated the pooled prevalence of OSA by both industry and occupation by separating samples by Standard Industry Classification and Standard Occupation Classification.</p><p><strong>Results: </strong>The overall OSA prevalence estimated by imputation for ages 40-64 was 17.8% (95% CI = 15.9% to 19.9%). Separating those samples into industrial/occupational groups, the estimated prevalence of OSA varied widely by industry/occupation. Descriptive analysis revealed that the estimated prevalence of OSA was relatively higher in the Accommodation and food, Public administration and defence; compulsory social security, Construction industries, and Protective service occupations, health and social care associate professionals, and skilled construction and building trades occupations.</p><p><strong>Conclusions: </strong>In England in 2019, Accommodation and food, Public administration and defence; compulsory social security, Construction industries, and Protective service occupations, health and social care associate professionals, and skilled construction and building trades occupations showed a relatively higher prevalence of OSA indicating that they may be target populations for workplace screening.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae069"},"PeriodicalIF":0.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11452655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary report: Sleep duration during late pregnancy predicts postpartum emotional responses among parents at risk for postpartum depression.","authors":"Gina M Mason, Zachary L Cohen, Jessica Obeysekare, Jared M Saletin, Katherine M Sharkey","doi":"10.1093/sleepadvances/zpae068","DOIUrl":"10.1093/sleepadvances/zpae068","url":null,"abstract":"<p><strong>Introduction: </strong>Sleep loss is common during the perinatal period; however, few studies have assessed potential consequences of insufficient sleep for postnatal emotional responding, a key contributor to parenting behaviors with implications for parent-infant bonding and mental health. To generate hypotheses for future work assessing perinatal sleep and emotion-related outcomes, this pilot study explored whether prenatal sleep duration predicted postnatal emotional responding in a sample at risk for postpartum depression.</p><p><strong>Methods: </strong>Participants were nine birthing parents with a prior mood disorder who were not in a current episode at enrollment. We estimated sleep with actigraphy collected for 1 week at 33 weeks' gestation and at 2 and 6 weeks postpartum. Following each week, participants completed an emotional evaluation task, rating the valence and arousal of standardized images from the International Affective Picture System. We tested whether average prenatal (33 weeks) nighttime sleep duration predicted concurrent and future responsiveness to emotional images, quantified by participants' reaction times and arousal/valence ratings.</p><p><strong>Results: </strong><i>Shorter prenatal sleep</i> duration predicted <i>faster reaction times</i>, both concurrently and at 2 weeks postpartum (<i>ps</i> ≤ .05), as well as <i>lower arousal ratings for negative images</i> at 2 and 6 weeks postpartum (<i>p</i>s ≤ .043).</p><p><strong>Conclusions: </strong>In this small sample of birthing parents at risk for postpartum depression, shorter prenatal sleep duration predicted faster reactions to emotional stimuli and blunted arousal responses to negative images. Although preliminary, these findings justify further study of the role of prenatal sleep in postpartum emotional responses and how these factors may impact parent-infant outcomes.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae068"},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic characteristics and comorbidities of patients with narcolepsy: a propensity-matched cohort study.","authors":"Melissa C Lipford, Wui Ip, Samir Awasthi, J Layne Moore, Maja Tippmann-Peikert, Shahir Asfahan, Praveen Kumar-M, Gajinder Pal Singh, Jennifer Gudeman","doi":"10.1093/sleepadvances/zpae067","DOIUrl":"https://doi.org/10.1093/sleepadvances/zpae067","url":null,"abstract":"<p><strong>Study objectives: </strong>Narcolepsy has a complex phenotype owing to differences in symptomatology, disease severity, and comorbidities. This is the first study to use aggregate electronic health record (EHR) data and natural language processing (NLP) algorithms to characterize the demographics and comorbidities of a large cohort of patients with narcolepsy.</p><p><strong>Methods: </strong>First-time Mayo Clinic patients (2000-2020) who had ≥1 narcolepsy-specific ICD-9/10 code and ≥1 disease-supportive statement in the clinical notes (identified using an NLP algorithm) were identified. A control cohort was propensity matched for birth year, age at first institutional encounter, sex, race, ethnicity, number of diagnosis codes, and mortality. Common comorbidities were compared and ranked between cohorts.</p><p><strong>Results: </strong>In the EHR database (<i>N</i> = 6 389 186 patients), 2057 patients with narcolepsy were identified (median age, 32 years; 59.6% female; 92.6% white; and 89.2% non-Hispanic) and propensity matched with a control cohort. Among the top 20 comorbidities occurring more frequently in the narcolepsy cohort compared with the control cohort (odds ratio [OR], 1.67-3.94; <i>p</i> < .001]) were sleep disorders (restless legs syndrome, obstructive sleep apnea, and insomnia), mood disorders (depression, dysthymia, and anxiety), and pain disorders (chronic pain syndrome, migraine, fibromyalgia, carpal tunnel syndrome, and myalgia). Other comorbidities significantly associated with narcolepsy (OR, 1.33-1.95) were irritable bowel syndrome (<i>p</i> < .001), asthma (<i>p</i> < .001), cervical spondylosis (<i>p</i> < .01), syncope (<i>p</i> < .01), and hypothyroidism (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>This propensity-matched cohort study demonstrates increased psychiatric, sleep, and pain disorders in patients living with narcolepsy and challenges beyond narcolepsy-specific symptoms in this population. Understanding common narcolepsy-associated comorbidities may assist in tailoring treatment modalities.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae067"},"PeriodicalIF":0.0,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in the role of sleep on cognition in older adults.","authors":"Yumiko Wiranto, Catherine Siengsukon, Diego R Mazzotti, Jeffrey M Burns, Amber Watts","doi":"10.1093/sleepadvances/zpae066","DOIUrl":"10.1093/sleepadvances/zpae066","url":null,"abstract":"<p><strong>Study objectives: </strong>The study aimed to investigate sex differences in the relationship between sleep quality (self-report and objective) and cognitive function across three domains (executive function, verbal memory, and attention) in older adults.</p><p><strong>Methods: </strong>We analyzed cross-sectional data from 207 participants with normal cognition (NC) or mild cognitive impairment (89 males and 118 females) aged over 60 years. The relationship between sleep quality and cognitive performance was estimated using generalized additive models. Objective sleep was measured with the GT9X Link ActiGraph, and self-reported sleep was measured with the Pittsburgh Sleep Quality Index.</p><p><strong>Results: </strong>We found that females exhibited lower executive function with increased objective total sleep time, with a steeper decline in performance after 400 minutes (<i>p</i> = .015). Additionally, longer objective sleep correlated with lower verbal memory linearly (<i>p</i> = .046). In males, a positive linear relationship emerged between objective sleep efficiency and executive function (<i>p</i> = .036). Self-reported sleep was not associated with cognitive performance in females and males with NC. However, in males with cognitive impairment, there was a nonlinear positive relationship between self-reported sleep and executive function (<i>p</i> < .001).</p><p><strong>Conclusions: </strong>Our findings suggest that the association between sleep parameters on cognition varies between older males and females, with executive function being most strongly associated with objective sleep for both sexes top of form. Interventions targeting sleep quality to mitigate cognitive decline in older adults may need to be tailored according to sex, with distinct approaches for males and females.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae066"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11450268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extending weeknight sleep duration in late-sleeping adolescents using morning bright light on weekends: a 3-week maintenance study.","authors":"Stephanie J Crowley, Elaine Poole, John Adams, Charmane I Eastman","doi":"10.1093/sleepadvances/zpae065","DOIUrl":"10.1093/sleepadvances/zpae065","url":null,"abstract":"<p><strong>Study objectives: </strong>Our sleep extension intervention in adolescents showed that gradually shifting weekday bedtime earlier plus one weekend of morning bright light advanced circadian phase and increased weeknight sleep duration. Here, we examine at-home maintenance of these changes.</p><p><strong>Methods: </strong>Fourteen adolescents (15.3-17.9 years; 7 female) completed a 7-week study. After usual sleep at home (2-week baseline), intervention participants (<i>n</i> = 8) gradually advanced weekday bedtime (1 hour earlier than baseline during week 3; 2 hours earlier in week 4) and received bright light (~6000 lux; 2.5 hours) on both mornings of the intervening weekend. During three maintenance weeks, intervention participants were instructed to maintain their school-day wake-up time on all days, keep their early week four bedtimes, except on weekends when they could go to bed up to 1 hour later, and get a 2.5-hour light box exposure within 5 minutes of waking on one morning (Saturday or Sunday) of both weekends at home. Control participants (<i>n</i> = 6) slept as usual at home and did not receive weekend bright light. Dim light melatonin onset (DLMO) was measured after the 2-week baseline, 2-week intervention, and 3-week maintenance in all participants. Actigraphic sleep-wake was collected throughout.</p><p><strong>Results: </strong>After the 2-week intervention, DLMOs advanced more compared to control (37.0 ± 40.0 minutes vs. -14.7 ± 16.6 minutes), weekday sleep duration increased by 69.7 ± 27.8 minutes and sleep onset was 103.7 ± 14.2 minutes earlier compared to baseline. After three maintenance weeks, intervention participants showed negligible DLMO delays (-4.9 ± 22.9 minutes); weekday fall-asleep times and sleep durations also remained stable.</p><p><strong>Conclusions: </strong>Early circadian phase and extended sleep can be maintained with at-home weekend bright light.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":"5 1","pages":"zpae065"},"PeriodicalIF":0.0,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11417015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}