American journal of epidemiology最新文献_第8页

Patterns of Cohort Participation Among People with Systemic Sclerosis in an Open Cohort: a Scleroderma Patient-centered Intervention Network Cohort Study. 开放队列中系统性硬化症患者的队列参与模式：一项以硬皮病患者为中心的干预网络队列研究

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-08 DOI: 10.1093/aje/kwag217

Meira Golberg, Marie-Eve Carrier, Linda Kwakkenbos, Susan J Bartlett, Catherine Fortuné, Amy Gietzen, Karen Gottesman, Geneviève Guillot, Maureen D Mayes, Michelle Richard, Maureen Sauvé, Robyn K Wojeck, Luc Mouthon, Andrea Benedetti, Brett D Thombs, On Behalf Of The Spin Investigators

{"title":"Patterns of Cohort Participation Among People with Systemic Sclerosis in an Open Cohort: a Scleroderma Patient-centered Intervention Network Cohort Study.","authors":"Meira Golberg, Marie-Eve Carrier, Linda Kwakkenbos, Susan J Bartlett, Catherine Fortuné, Amy Gietzen, Karen Gottesman, Geneviève Guillot, Maureen D Mayes, Michelle Richard, Maureen Sauvé, Robyn K Wojeck, Luc Mouthon, Andrea Benedetti, Brett D Thombs, On Behalf Of The Spin Investigators","doi":"10.1093/aje/kwag217","DOIUrl":"https://doi.org/10.1093/aje/kwag217","url":null,"abstract":"Participants who continue across the full duration of longitudinal studies often differ from those lost to attrition, defined as discontinuing participation for any reason, and some participants may sporadically miss assessments. Complex participation patterns, such as in multicenter chronic disease cohorts, have not been studied. We aimed to implement an approach to identify participation subgroups and factors associated with theses. We applied our approach in the SPIN Cohort, a multicenter, longitudinal systemic sclerosis (SSc) cohort, because it is an example of an open-ended cohort with no planned end date and complex participation patterns. We used group-based trajectory modeling to identify participation subgroups and multinomial logistic regression to identify predictors of subgroup membership. Data were obtained for 2883 participants from 54 sites in 7 countries. We identified 5 participation subgroups: Ongoing Participation (29%), Immediate Attrition (29%), Mid-Term Attrition (19%), Long-Term Attrition (12%), and Ongoing Sporadic (11%) participation. Older age and sites outside the United States were associated with lower odds of belonging to all subgroups other than Ongoing Participation. Compared to Ongoing Participation, several sociodemographic variables were associated with higher odds of being in the Immediate Attrition group. Our method can be applied to other cohorts with complex participation patterns.","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cumulative layoffs in adulthood and cognitive function in mid-to-later life among US working-age adults, 1979-2020. 1979-2020年美国工作年龄成年人的成年累积裁员和中老年认知功能。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-08 DOI: 10.1093/aje/kwag218

Xuexin Yu, Katrina L Kezios, Antonio J Bustillo, Martine Elbejjani, Allison E Aiello, Adina Zeki Al Hazzouri

{"title":"Cumulative layoffs in adulthood and cognitive function in mid-to-later life among US working-age adults, 1979-2020.","authors":"Xuexin Yu, Katrina L Kezios, Antonio J Bustillo, Martine Elbejjani, Allison E Aiello, Adina Zeki Al Hazzouri","doi":"10.1093/aje/kwag218","DOIUrl":"https://doi.org/10.1093/aje/kwag218","url":null,"abstract":"As one of the most disruptive life events, layoffs are pervasive in the US labor market, while little is known about cumulative layoff experience across adulthood in relation to subsequent cognitive function. We investigated the association between cumulative layoffs spanning over 41 years of adulthood and subsequent domain-specific cognition among US working-age adults. Data were from 6421 adults in National Longitudinal Survey of Youth 1979. Cumulative layoff experience was defined as the number of jobs ending in a layoff from 1979-2020: zero (never, n = 4503), one (n = 1402), and ≥ two (n = 516). Domain-specific latent cognitive factor scores were assessed in 2020 using confirmatory factor analysis. Multivariable-adjusted linear regression models were fit to investigate the association of interest. Results suggest that cumulative layoff experience was associated with lower latent factor scores in episodic memory (β = -0.045, 95% CI: -0.100 to 0.010, one layoff vs. never; β = -0.086, 95% CI: -0.171 to -0.001, ≥two layoffs vs. never; P trend 0.037), but not in attention, orientation, or language domains. Given its ubiquity in the US labor market, layoffs may represent an important and understudied risk factor for episodic memory function among US adults.","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gestational Diabetes Mellitus in Second Pregnancy by Adverse Outcomes of First Pregnancy: a Population-based Historical Cohort Study. 妊娠糖尿病与第一妊娠不良结局：一项基于人群的历史队列研究

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-08 DOI: 10.1093/aje/kwag213

Linn Marie Sørbye, Roy Miodini Nilsen, Kari Klungsøyr, Nils-Halvdan Morken, Liv Grimstvedt Kvalvik, Ellen Aagaard Nohr, Rolv Skjaerven, Janet Catov

{"title":"Gestational Diabetes Mellitus in Second Pregnancy by Adverse Outcomes of First Pregnancy: a Population-based Historical Cohort Study.","authors":"Linn Marie Sørbye, Roy Miodini Nilsen, Kari Klungsøyr, Nils-Halvdan Morken, Liv Grimstvedt Kvalvik, Ellen Aagaard Nohr, Rolv Skjaerven, Janet Catov","doi":"10.1093/aje/kwag213","DOIUrl":"https://doi.org/10.1093/aje/kwag213","url":null,"abstract":"We investigated combinations of preterm birth, preeclampsia and offspring birthweight by gestational age in a first pregnancy and cross-over risk of gestational diabetes mellitus (GDM) in second pregnancy. The Medical Birth Registry of Norway provided data for 561 873 mothers with first and second births without diabetes prior to second pregnancy, 1985-2020. We combined first pregnancy preterm birth (<37 weeks), preeclampsia and birthweight by gestational age quartiles (Q1-4) into one exposure (16 categories). Relative risks with 95% confidence intervals for GDM in second pregnancy were estimated, keeping mothers with first term birth without preeclampsia and offspring in Q1 as reference. Women with first offsprings in Q4 had high risk of subsequent GDM, however, in combinations with preterm birth and preeclampsia the risk of GDM progressively increased: Compared to 0.9% GDM risk in the reference group, the risk increased to 1.8% for Q4 term births without preeclampsia (aRR 2.1 [95% confidence interval 2.0-2.3]), 2.5% for Q4 preterm births without preeclampsia (aRR 3.3 [2.8-3.8]), 4.2% for Q4 term birth with preeclampsia (aRR 5.6 [4.8-6.4]) and 7.8% for Q4 preterm birth with preeclampsia (aRR 10.1 [7.4-13.7]). Combinations of first pregnancy exposures were associated with a progressive cross-over risk of GDM in second pregnancy.","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What happens to your manuscript: characteristics of papers published in volume 194 of the American Journal of Epidemiology. 你的手稿怎么处理：发表在《美国流行病学杂志》第194卷上的论文的特征。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-08 DOI: 10.1093/aje/kwag212

Sita Lujintanon, Catherine R Lesko, Lorraine T Dean, John W Jackson, Harriett Telljohann, Enrique F Schisterman, On Behalf Of The Editorial Board

引用次数: 0

Correction to: How to identify the healthy worker survivor effect empirically and how to interpret results from published studies: the National Institute for Occupational Safety and Health ethylene oxide cohort as a case study. 更正：如何从经验上确定健康工人幸存者效应以及如何解释已发表研究的结果：国家职业安全与健康研究所环氧乙烷队列作为案例研究。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-04 DOI: 10.1093/aje/kwag202

引用次数: 0

Doubly Robust Methods for Recurrent Event Outcomes: Causal Effects of Blood Pressure Medications on Acute Kidney Injuries. 复发事件结局的双重可靠方法：降压药物对急性肾损伤的因果影响。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-04 DOI: 10.1093/aje/kwag214

Wenling Hang, Cecilia A Cotton, Lan Wen

引用次数: 0

Changes in COVID-19-related death certification practices and quality of cause-of-death reporting in the United States from 2020 to 2023. 2020年至2023年美国与covid -19相关的死亡证明做法和死因报告质量的变化

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-04 DOI: 10.1093/aje/kwag215

Shu-Yu Tai, Yu-Wen Chien, Ichiro Kawachi, Tsung-Hsueh Lu

{"title":"Changes in COVID-19-related death certification practices and quality of cause-of-death reporting in the United States from 2020 to 2023.","authors":"Shu-Yu Tai, Yu-Wen Chien, Ichiro Kawachi, Tsung-Hsueh Lu","doi":"10.1093/aje/kwag215","DOIUrl":"https://doi.org/10.1093/aje/kwag215","url":null,"abstract":"This study examined changes in COVID-19-related death certification practices (ie, reporting COVID-19 in Part I of the death certificate) and the quality of cause-of-death (COD) reporting (acceptable and rejected causal sequences) in the United States from 2020 to 2023. In 2020, 2021, 2022, and 2023, 385 293, 463 273, 246 196, and 76 024 death certificates, respectively, mentioned COVID-19. COVID-19 was selected as the underlying COD in 91%, 90%, 76%, and 65% of these certificates, corresponding to reporting COVID-19 in Part I in 93%, 91%, 78%, and 67% of certificates, respectively. Acceptable causal sequences were reported in 51%, 51%, 45%, and 41% of certificates, whereas rejected causal sequences were reported in 21%, 22%, 23%, and 23%, respectively. Using 2020 as the reference year, the adjusted odds ratios (95% confidence intervals) for 2023 were 0.18 (0.18, 0.18) for reporting COVID-19 in Part I, 0.77 (0.76, 0.78) for reporting acceptable causal sequences, and 1.14 (1.12, 1.16) for reporting rejected causal sequences. In conclusion, COVID-19-related death certification practices changed substantially over the study period, paralleling the decline in the virulence of SARS-CoV-2. The quality of COVID-19-related COD reporting declined modestly from 2020 to 2023.","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Sampling for computational efficiency when conducting analyses in big data. 修正：在进行大数据分析时为提高计算效率而进行抽样。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-03 DOI: 10.1093/aje/kwag152

引用次数: 0

Critical gestational windows of heat exposure associated with preterm birth: a nationwide observational study. 热暴露与早产相关的关键妊娠期窗：一项全国性的观察性研究。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-03 DOI: 10.1093/aje/kwag070

Shuhei Terada, Hisaaki Nishimura, Naoyuki Miyasaka, Nobutoshi Nawa, Takeo Fujiwara

{"title":"Critical gestational windows of heat exposure associated with preterm birth: a nationwide observational study.","authors":"Shuhei Terada, Hisaaki Nishimura, Naoyuki Miyasaka, Nobutoshi Nawa, Takeo Fujiwara","doi":"10.1093/aje/kwag070","DOIUrl":"10.1093/aje/kwag070","url":null,"abstract":"Emerging evidence links high ambient temperature to an increased risk of preterm birth (PTB), yet the critical gestational windows of heat exposure remain unclear. We analyzed data from the Japan Perinatal Registry Network (2016-2020), including 986 207 singleton live births. Weekly heat exposure was defined using the prefecture-specific annual 90th percentile of weekly mean temperature, with analyses restricted to May-September. Logistic regression models were fitted for each gestational week from -12 to 35, adjusting for maternal age, parity, pre-pregnancy body mass index, smoking status, history of PTB, the weekly moving average of relative humidity, and month and year of conception. Critical windows were identified using Bayesian hierarchical modeling with smoothing and variable selection. Heat exposure was associated with increased PTB risk during gestational weeks 16-22, peaking at week 19 (odds ratio: 1.16; 95% credible interval: 1.13-1.19). Subtype analyses indicated peak susceptibility at week 16 for extremely preterm (<28 weeks), week 18 for very preterm (28-31 weeks), and week 19 for moderate-to-late preterm (32-36 weeks) births. Modest inverse associations were observed in early gestation. These results indicate that the second trimester, particularly gestational weeks 16-22, may represent a critical window for heat-related PTB, underscoring the importance of targeted preventive strategies.","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":"2364-2372"},"PeriodicalIF":4.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147571779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cumulative environmental burden and neurodegenerative disease mortality: a national ecological study in the United States. 累积环境负担和神经退行性疾病死亡率：美国的一项国家生态研究。

IF 4.1 2区医学

American journal of epidemiology Pub Date : 2026-09-03 DOI: 10.1093/aje/kwag114

Guoli Ma, Yu Shi, Junlan Qiu, Chao Ren, Konglan Shao, Xiaochen Shu

{"title":"Cumulative environmental burden and neurodegenerative disease mortality: a national ecological study in the United States.","authors":"Guoli Ma, Yu Shi, Junlan Qiu, Chao Ren, Konglan Shao, Xiaochen Shu","doi":"10.1093/aje/kwag114","DOIUrl":"10.1093/aje/kwag114","url":null,"abstract":"Neurodegenerative diseases (NDDs) represent a growing cause of mortality and disability among aging populations worldwide. However, the relationship between cumulative, multidomain environmental exposures, and NDD mortality remains poorly characterized. This study aimed to examine the association between comprehensive environmental quality and NDD mortality in the United States. We used the environmental quality index (EQI) from 2000 to 2005 to characterize cumulative environmental exposure. Associations between EQI quintiles and NDD mortality, including dementia, Parkinson's disease (PD), amyotrophic lateral sclerosis, and Huntington's disease, were examined using Bayesian interval-censored mixed-effects models. During 2006-2020, among 3.66 million NDD deaths, poorer environmental quality (Q5 vs Q1) was associated with mortality rate differences of 24.72 (95% credible intervals [CrI]: 22.43, 27.06) per 100 000 at 5-year lag, 26.74 (95% CrI: 24.34, 29.21) at 10-year lag, and 22.74 (95% CrI: 20.49, 25.13) at 15-year lag. Within each lag period, a clear dose-response pattern was consistently observed across EQI quintiles. Furthermore, associations were most pronounced for the air quality, followed by sociodemographic disadvantage. In addition, demographic and geographic heterogeneity was observed across sex, race, census regions, urbanicity, climate zone, and county economic type. These findings underscore the need for integrated, place-based environmental health policies targeting neurodegeneration prevention.","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":"2440-2449"},"PeriodicalIF":4.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0