American journal of epidemiology最新文献

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Correction to: Comparison of caffeine consumption behavior with plasma caffeine levels as exposure measures in drug-target mendelian randomization.
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-23 DOI: 10.1093/aje/kwae450
{"title":"Correction to: Comparison of caffeine consumption behavior with plasma caffeine levels as exposure measures in drug-target mendelian randomization.","authors":"","doi":"10.1093/aje/kwae450","DOIUrl":"https://doi.org/10.1093/aje/kwae450","url":null,"abstract":"","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimorbidity patterns, sociodemographic characteristics, and mortality: Data science insights from low-resource settings.
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-19 DOI: 10.1093/aje/kwae466
Juan Carlos Bazo-Alvarez, Darwin Del Castillo, Luis Piza, Antonio Bernabé-Ortiz, Rodrigo M Carrillo-Larco, Liam Smeeth, Robert H Gilman, William Checkley, J Jaime Miranda
{"title":"Multimorbidity patterns, sociodemographic characteristics, and mortality: Data science insights from low-resource settings.","authors":"Juan Carlos Bazo-Alvarez, Darwin Del Castillo, Luis Piza, Antonio Bernabé-Ortiz, Rodrigo M Carrillo-Larco, Liam Smeeth, Robert H Gilman, William Checkley, J Jaime Miranda","doi":"10.1093/aje/kwae466","DOIUrl":"https://doi.org/10.1093/aje/kwae466","url":null,"abstract":"<p><p>Multimorbidity data is typically analysed by tallying disease counts, which overlooks nuanced relationships among conditions. We identified clusters of multimorbidity and subpopulations with varying risks and examined their association with all-cause mortality using a data-driven approach. We analysed 8-year follow-up data of people ≥35 years who were part of the CRONICAS Cohort Study, a multisite cohort from Peru. First, we used Partitioning Around Medoids and multidimensional scaling to identify multimorbidity clusters. We then estimated the association between multimorbidity clusters and all-cause mortality. Second, we identified subpopulations using finite mixture modelling. Our analysis revealed three clusters of chronic conditions: respiratory (cluster 1: bronchitis, COPD and asthma), lifestyle, hypertension, depression and diabetes (cluster 2), and circulatory (cluster 3: heart disease, stroke and peripheral artery disease). While only the cluster comprising circulatory diseases showed a significant association with all-cause mortality in the overall population, we identified two latent subpopulations (named I and II) exhibiting differential mortality risks associated with specific multimorbidity clusters. These findings underscore the importance of considering multimorbidity clusters and sociodemographic characteristics in understanding mortality risks. They also highlight the need for tailored interventions to address the unique needs of different subpopulations living with multimorbidity to reduce mortality risks effectively.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Fatal Suicidal Self-Directed Violence among U.S. Veterans (2022): The Assessing Social and Community Environments with National Data (ASCEND) for Veteran Suicide Prevention Study.
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-17 DOI: 10.1093/aje/kwae461
Claire A Hoffmire, Sean M Barnes, Ryan Holliday, Julie A Kittel, Alexandra L Schneider, Lisa A Brenner, Jamie L Tock, Lindsey L Monteith
{"title":"Non-Fatal Suicidal Self-Directed Violence among U.S. Veterans (2022): The Assessing Social and Community Environments with National Data (ASCEND) for Veteran Suicide Prevention Study.","authors":"Claire A Hoffmire, Sean M Barnes, Ryan Holliday, Julie A Kittel, Alexandra L Schneider, Lisa A Brenner, Jamie L Tock, Lindsey L Monteith","doi":"10.1093/aje/kwae461","DOIUrl":"https://doi.org/10.1093/aje/kwae461","url":null,"abstract":"<p><p>From 2001-2021, the age- and sex-adjusted Veteran suicide rate increased 76.3%. Surveillance of suicidal ideation (SI) and non-fatal suicidal self-directed violence (NF-SSDV) is a critical component of public health-oriented suicide prevention efforts. To facilitate national NF-SSDV surveillance, a biennial, population-based survey was initiated: Assessing Social and Community Environments with National Data (ASCEND) for Veteran Suicide Prevention. 17,396 Veterans participated in the first large-scale ASCEND survey (2022). This manuscript reports on SI and NF-SSDV prevalence among Veterans residing in the continental U.S., Hawaii, and Puerto Rico. Lifetime SI was reported by 31.98% (95%CI=30.97-32.99), post-military SI by 25.88% (95%CI=24.91-26.85) and past-year SI by 12.69% (95%CI=11.90-13.47). The most commonly considered SI method among those with past-year SI was gunshot. Additionally, 34.42% (95%CI=33.07-35.78) of Veterans with lifetime SI reported lifetime preparatory behaviors. Moreover, 9.13% (95%CI=8.43-9.82) of Veterans reported lifetime interrupted attempts. Lifetime suicide attempts (SA) were reported by 6.99% (95%CI=6.41-7.56) of Veterans, with 4.88% (95%CI=4.39-5.36) reporting post-military SA. The most common method in prior attempts was medication overdose. ASCEND provides a novel opportunity to elucidate the prevalence of SI and different types of NF-SSDV in the Veteran population. Recurring administration will elucidate changes in SI and NF-SSDV prevalence in the Veteran population over time.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A hypothetical intervention on the use of hearing aids for the risk of dementia in people with hearing loss in UK Biobank.
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-16 DOI: 10.1093/aje/kwae452
J Mur, M Klee, H R Wright, A Solomon, C Johnson, T J Littlejohns, G Muniz-Terrera, A K Leist
{"title":"A hypothetical intervention on the use of hearing aids for the risk of dementia in people with hearing loss in UK Biobank.","authors":"J Mur, M Klee, H R Wright, A Solomon, C Johnson, T J Littlejohns, G Muniz-Terrera, A K Leist","doi":"10.1093/aje/kwae452","DOIUrl":"https://doi.org/10.1093/aje/kwae452","url":null,"abstract":"<p><p>Observational studies have reported that hearing aid (HA) use is associated with a reduced risk of dementia diagnosis, suggesting a possible protective effect. However, extant observational studies do not explicitly model causal effects, while randomised controlled trials on the effect of HA on dementia exhibit short follow-up. Here we used self-report, hearing tests, and healthcare records in UK Biobank to design a hypothetical intervention for the effect of HA use on the risk of dementia diagnosis in people with incident hearing loss (HL). HA users exhibited a higher risk of dementia diagnosis than non-users (RR=1.43, 95%CI=1.08-1.88). Associations between HA use and dementia diagnosis were robust across sensitivity analyses (RRs: 1.34-1.59) but adjustment for primary healthcare utilisation (0.77, 0.44-1.33) or primary and secondary care utilisation (0.68, 0.39-1.18) substantially decreased the observed effect. The decrease in effect estimates upon adjustment for primary (1.30, 0.95-1.78) and primary and secondary healthcare utilisation (1.30, 0.94-1.78) was smaller when participants with relatively early diagnoses of HL were included in the sample compared to when they were not. While the findings are not conclusive, they suggest residual confounding by healthcare utilisation and dating of HL diagnosis in participants without primary care data in UK Biobank.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142826927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
State-level changes in racial disparities in probation and parole rates in the United States, 2001-2018. 2001-2018 年美国州一级缓刑和假释率种族差异的变化。
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-16 DOI: 10.1093/aje/kwae460
David Rigby, Daichi Hibi, Ruth Wygle, Hedwig Lee, Joan Casey, Alison Gemmill, Tim Bruckner
{"title":"State-level changes in racial disparities in probation and parole rates in the United States, 2001-2018.","authors":"David Rigby, Daichi Hibi, Ruth Wygle, Hedwig Lee, Joan Casey, Alison Gemmill, Tim Bruckner","doi":"10.1093/aje/kwae460","DOIUrl":"https://doi.org/10.1093/aje/kwae460","url":null,"abstract":"<p><p>Although the public health field has increasingly studied the collateral consequences of incarceration, we know little about the health consequences of other forms of criminal legal contact, including probation and parole. Understanding spatial and racial-ethnic variation in probation/parole across US states provides new insights into how community supervision impacts population health disparities. However, state-level probation/parole prevalence has not been adequately described. Using data from the Bureau of Justice Statistics and the Census for the years 2001 to 2018, we provide the first state-level estimates of probation and parole populations by race over time in the US. We find large variation in disparities across states and time that is masked by national-level estimates. The US probation population decreased, and its racial composition remained steady between 2001 and 2018. However, in all but five states, the Black-White gap in probation rates declined. The Black-White gap in parole rates declined in all but seven states. The extent to which these race-specific changes in probation or parole over time reflect adjudication processes favoring White people, and/or affect population health, warrant further investigation.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Labor and delivery unit practices and racial and ethnic disparities in severe maternal and neonatal morbidity among nulliparous individuals with low-risk pregnancies.
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-16 DOI: 10.1093/aje/kwae459
Stephanie A Leonard, Xiao Xu, Shantay Davies-Balch, Elliott K Main, Brian T Bateman, David H Rehkopf, Henry C Lee, Jessica Illuzzi, Irogue Igbinosa, Ijeoma Iwekaogwu, Deirdre J Lyell
{"title":"Labor and delivery unit practices and racial and ethnic disparities in severe maternal and neonatal morbidity among nulliparous individuals with low-risk pregnancies.","authors":"Stephanie A Leonard, Xiao Xu, Shantay Davies-Balch, Elliott K Main, Brian T Bateman, David H Rehkopf, Henry C Lee, Jessica Illuzzi, Irogue Igbinosa, Ijeoma Iwekaogwu, Deirdre J Lyell","doi":"10.1093/aje/kwae459","DOIUrl":"https://doi.org/10.1093/aje/kwae459","url":null,"abstract":"<p><p>Persistent racial and ethnic disparities exist in severe maternal and neonatal morbidity, which may be due in part to differences in labor and delivery unit practices across hospitals. We used data collected from 184 hospitals in California (2015-2018) to assess whether nulliparous individuals with low-risk pregnancies differ by race and ethnicity in giving birth at hospitals that tend to use lower-interventional labor and delivery unit practices, and whether such differences contribute to disparities in severe maternal and neonatal morbidity. We classified labor and delivery units as higher- or lower-interventional based on a latent class analysis of survey responses about the frequency of using lower-interventional practices. We used a modified doubly robust g-estimator to estimate counterfactual disparity measures, setting all hospitals to be lower-interventional. Among 348,990 low-risk livebirths, the proportion occurring at lower-interventional hospitals was lowest in Black and Latino individuals (17% and 16%, respectively) and highest in American Indian and Alaska Native (AI/AN) and White individuals (29% in both). Severe maternal and neonatal morbidity occurred most frequently among AI/AN individuals. Counterfactual disparity measures suggested that if all births occurred at lower-interventional hospitals, racial and ethnic disparities in the outcomes would modestly increase, except for severe neonatal morbidity among AI/AN individuals.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Green Heart Project: Objectives, Design, and Methods. 绿心项目:目标、设计和方法
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-16 DOI: 10.1093/aje/kwae458
Aruni Bhatnagar, Rachel Keith, Ray Yeager, Daniel Riggs, Clara Sears, Brent Bucknum, Ted Smith, Daniel Fleischer, Chris Chandler, Kandi L Walker, Joy L Hart, Sanjay Srivastava, Jay Turner, Shesh Rai
{"title":"The Green Heart Project: Objectives, Design, and Methods.","authors":"Aruni Bhatnagar, Rachel Keith, Ray Yeager, Daniel Riggs, Clara Sears, Brent Bucknum, Ted Smith, Daniel Fleischer, Chris Chandler, Kandi L Walker, Joy L Hart, Sanjay Srivastava, Jay Turner, Shesh Rai","doi":"10.1093/aje/kwae458","DOIUrl":"10.1093/aje/kwae458","url":null,"abstract":"<p><p>The Green Heart Project is a controlled, community-based clinical trial to evaluate the effects of increasing greenery on community health. The study was initiated in 2018 in a low-to-middle-income residential area of nearly 30,000 racially diverse residents in Louisville, KY. Community engagement was maintained throughout the project, with feedback integrated into its design and implementation. Based on land use, demographics, and greenness in the area, we designated 8 paired clusters of demographically- and environmentally matched \"target\" (T) and adjacent \"control\" (C) areas (total of 16 clusters). Levels of ultrafine particles, ozone, and nitrogen oxides were measured in each cluster. In-person exams were conducted for 735 participants in Wave 1 (2018-2019) and 545 participants in Wave 2 (2021). Blood, urine, nail, and hair samples were collected to evaluate cardiovascular risk, inflammation, stress, and pollutant exposure. Demographic and psychosocial data were collected as well. Cardiovascular function was assessed by measuring arterial stiffness and flow-mediated dilation. After Wave 2, more than 8,000 mature, mostly evergreen, trees and shrubs were planted in the T clusters. Post planting data were collected during Wave 3 (2022) from 561 participants. We plan to follow changes in area characteristics and participant health to evaluate the long-term impact of the greening intervention.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family criminal legal system exposure and early adolescents' pubertal development: The mediating role of family strain. 家庭刑事法律制度与青少年青春期发育:家庭压力的中介作用。
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-13 DOI: 10.1093/aje/kwae457
Juan Del Toro, Michael Roettger, Dylan B Jackson, Sylia Wilson
{"title":"Family criminal legal system exposure and early adolescents' pubertal development: The mediating role of family strain.","authors":"Juan Del Toro, Michael Roettger, Dylan B Jackson, Sylia Wilson","doi":"10.1093/aje/kwae457","DOIUrl":"https://doi.org/10.1093/aje/kwae457","url":null,"abstract":"<p><p>Pubertal trends, wherein adolescents today are experiencing puberty earlier than prior generations, have coincided with the expansion of the criminal legal system, which is disproportionately impacting communities of color. However, whether pubertal development and criminal legal system exposure among adolescents are inter-related is unknown. We tested whether family members' criminal legal system exposure predicted adolescents' pubertal development, whether family strain explained the relation between criminal legal system exposure and pubertal development, and whether race/ethnicity moderated our results. We used three yearly waves of longitudinal data among a national sample of 9,518 adolescents. Results illustrated that 40% of Black, 20% of Latinx, 16% of Other, and 10% of White adolescents experienced one or more family criminal legal system exposures. In structural equation models within a case-crossover design controlling for measured confounders and unmeasured confounders that do not change over time, including neighborhood-level socioeconomic status and crime, family criminal legal system exposure predicted adolescents' advanced pubertal development, and family strain explained this relation between family criminal legal system exposure and pubertal development. The United States' approach to law and order has public health implications that may be perpetuating health inequities, as accelerated pubertal development can have downstream consequences across the life course.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimating the undetected burden and the likelihood of strain persistence of drug-resistant Neisseria gonorrhoeae. 估计未检测到的耐药淋病奈瑟菌负担和菌株持续存在的可能性。
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-13 DOI: 10.1093/aje/kwae455
Kirstin I Oliveira Roster, Minttu M Rönn, Heather Elder, Thomas L Gift, Kathleen A Roosevelt, Joshua A Salomon, Katherine K Hsu, Yonatan H Grad
{"title":"Estimating the undetected burden and the likelihood of strain persistence of drug-resistant Neisseria gonorrhoeae.","authors":"Kirstin I Oliveira Roster, Minttu M Rönn, Heather Elder, Thomas L Gift, Kathleen A Roosevelt, Joshua A Salomon, Katherine K Hsu, Yonatan H Grad","doi":"10.1093/aje/kwae455","DOIUrl":"https://doi.org/10.1093/aje/kwae455","url":null,"abstract":"<p><p>Neisseria gonorrhoeae has developed resistance to all antibiotics recommended for treatment and reports of reduced susceptibility to ceftriaxone, the last-line treatment, are increasing. Since many asymptomatic infections remain undiagnosed and most diagnosed infections do not undergo antibiotic susceptibility testing, surveillance systems may underestimate resistant infections. In this modeling study, we simulated the spread of a new strain of ceftriaxone non-susceptible N. gonorrhoeae in a population comprising men who have sex with men as well as heterosexual men and women. We compared scenarios with varying strain characteristics and surveillance capacity. For each scenario, we estimated (i) the number of undetected infections of the novel strain and (ii) the likelihood of strain persistence in the absence of newly reported cases. Upon detection of one non-susceptible isolate, the undetected burden was an estimated 5.4 infections with substantial uncertainty (0-18 infections, 95% uncertainty interval). Without additional reports of non-susceptible infections over the subsequent 180 days, the estimate declined to 2.5 infections (0-10 infections). The likelihood of ongoing transmission also declined from 66% (26-86%) at first detection to 2% (0-10%) after 180 days. To extend the useful lifespan of last-line antibiotics, our model estimated the infection landscapes that could underlie data from surveillance systems.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between neighborhood walkability and physical activity in a community-based twin sample.
IF 5 2区 医学
American journal of epidemiology Pub Date : 2024-12-12 DOI: 10.1093/aje/kwae170
Glen E Duncan, Philip M Hurvitz, Bethany D Williams, Ally R Avery, Matthew J D Pilgrim, Siny Tsang, Ofer Amram, Stephen J Mooney, Andrew G Rundle
{"title":"Association between neighborhood walkability and physical activity in a community-based twin sample.","authors":"Glen E Duncan, Philip M Hurvitz, Bethany D Williams, Ally R Avery, Matthew J D Pilgrim, Siny Tsang, Ofer Amram, Stephen J Mooney, Andrew G Rundle","doi":"10.1093/aje/kwae170","DOIUrl":"https://doi.org/10.1093/aje/kwae170","url":null,"abstract":"<p><p>We investigated associations between neighborhood walkability and physical activity using twins (5477 monozygotic and same-sex dizygotic pairs) as \"quasi-experimental\" controls of genetic and shared environment (familial) factors that would otherwise confound exposure-outcome associations. Walkability comprised intersection density, population density, and destination accessibility. Outcomes included self-reported weekly minutes of neighborhood walking and moderate-to-vigorous physical activity (MVPA) and days per week using transit services (eg, bus, commuter rail). There was a positive association between walkability and walking, which remained significant after controlling for familial and demographic factors: a 1% increase in walkability was associated with a 0.42% increase in neighborhood walking. There was a positive association between walkability and MVPA, which was not significant after considering familial and demographic factors. In twins with at least 1 day of transit use, a 1-unit increase in log (walkability) was associated with a 6.7% increase in transit use days; this was not significant after considering familial and demographic factors. However, higher walkability reduced the probability of no transit use by 32%, considering familial and demographic factors. Using a twin design to improve causal inference, walkability was associated with walking, whereas walkability and both MVPA and absolute transit use were confounded by familial and demographic factors. This article is part of a Special Collection on Environmental Epidemiology.</p>","PeriodicalId":7472,"journal":{"name":"American journal of epidemiology","volume":" ","pages":""},"PeriodicalIF":5.0,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142817049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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