Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia最新文献

{"title":"Incidence of aneuploidy in embryos studied using PGT-A in Mexico: a clinical retrospective experience.","authors":"Eduardo Ponce-Najera, Diana María Ojeda-López, Rodolfo González-Holveman, Ricardo Rodríguez-Calderon, Karla Patricia Bedia-Mejía, Jose Carlos Salazar-Trujillo, Jorge Luis Lezama-Ruvalcaba, Carlos Gerardo Salazar López-Ortiz","doi":"10.61622/rbgo/2025rbgo87","DOIUrl":"10.61622/rbgo/2025rbgo87","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the relationship between aneuploidy and maternal age based on preimplantation genetic testing for aneuploidies (PGT-A) and the distribution of aneuploidy across individual chromosomes.</p><p><strong>Methods: </strong>This is a single-center retrospective cohort study. The study included patients who underwent PGT-A during their in vitro fertilization (IVF) cycle between 2016 and 2024. PGT-A was performed on 1,341 embryos from 481 patients using next-generation sequencing (NGS)-based techniques. We conducted a Logistic regression analysis to determine the relationship between maternal age and the rate of aneuploidy; additionally, the most commonly affected chromosome and the characteristics of the detected alterations were evaluated. Statistical analysis was performed using STATA v17.</p><p><strong>Results: </strong>Among all patients, the observed aneuploidy rate was 55.85%. In patients younger than 30 years, the aneuploidy rate was 26.92%, with a progressive increase to 62% in women older than 40 years. Chromosomes 22, 21, 16, and 15 were the most frequently affected. Logistic regression indicated that age is a significant predictive factor for aneuploidy (coefficient = 0.0956; p < 0.001), with an odds ratio of 1.10 (95% CI: 1.07-1.13), meaning that the probability of aneuploidy increases by approximately 10% for each additional year of age.</p><p><strong>Conclusion: </strong>Our results indicate that an increase in maternal age is significantly associated with a higher incidence of aneuploidy in embryos that underwent PGT-A. These findings are significant for patient counseling and optimizing embryo selection in assisted reproduction treatments.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145672995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Looking back to the recent past: the influence of national health policies and vaccination during the COVID-19 pandemic on maternal health.","authors":"Renato Teixeira Souza, Maria Laura Costa, Jessica Lynn Schue, Emily Miller, Rupali Jayant Limaye, Jose Guilherme Cecatti","doi":"10.61622/rbgo/2025rbgoedt11","DOIUrl":"10.61622/rbgo/2025rbgoedt11","url":null,"abstract":"","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quarterly injectable hormonal contraceptive does not increase the activity of the renin-angiotensin-aldosterone system in women without cardiovascular risk factors.","authors":"Alice Miranda de Oliveira, Priscilla Araújo Dos Santos, Pedro Elias Santos Souza, Marvyn de Santana do Sacramento, Clóvis Figueiredo Souza, Ana Marice Texeira Ladeia, Jefferson Petto","doi":"10.61622/rbgo/2025rbgo71","DOIUrl":"10.61622/rbgo/2025rbgo71","url":null,"abstract":"<p><strong>Objective: </strong>To test the hypothesis that the quarterly injectable contraceptive increases the activity of the renin-angiotensin-aldosterone system.</p><p><strong>Methods: </strong>This was a cross-sectional observational study that included eutrophic, irregularly active women, aged between 18 and 30 years, who had been taking quarterly injectable contraceptive (150mg of medroxyprogesterone acetate) for at least 6 months or who had not used any type of hormonal contraceptive for at least 6 months. At first the volunteers underwent a physical examination and answered a standard questionnaire. They were then sent for blood collection of laboratory variables: plasma renin activity and concentration, angiotensin-converting enzyme 1 (ACE 1), and aldosterone. The data was analyzed using the two-tailed Student's t-test, with significance <0.05.</p><p><strong>Results: </strong>Sixty-two women were included in this study, divided into the Injectable Contraceptive Group (ICG) with n=23 and the No Contraceptive Group (NCG) with n=39. ICG had lower mean plasma renin activity values than NCG, respectively 0.4 ± 0.17 vs 1 ± 0.6 (p <0.01). The mean values for plasma renin concentration, ACE 1, and aldosterone did not differ between the groups (respectively, p= 0.21; 0.66; 0.09).</p><p><strong>Conclusion: </strong>Women using quarterly injectable contraceptives do not show greater activity of the renin-angiotensin-aldosterone system than their counterparts who do not use this drug.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal sacrocolpopexy: could we simplify the technique?","authors":"Edilson Benedito de Castro, Andressa Soares Castro Alves, Luiz Gustavo de Oliveira Brito, Glaucia Miranda Varella Pereira, Juliana do Carmo Fazzolari, Cássia Raquel Teatin Juliato","doi":"10.61622/rbgo/2025rbgo74","DOIUrl":"10.61622/rbgo/2025rbgo74","url":null,"abstract":"<p><strong>Objective: </strong>To compare the efficacy of a traditional open ASC technique (ASC-T) to an open modified technique (ASC-M).</p><p><strong>Methods: </strong>Retrospective cohort study with stage 3 or 4 apical prolapse women, who operated on using one of the two techniques were included in the study: ASC-T (vaginal mesh is secured with eight sutures) and ASC-M (four sutures). The POP-Q was used to objectively assess anatomical improvement. Women with less than one year of follow-up, without POP-Q classification, or with incomplete data were excluded.</p><p><strong>Results: </strong>A total of 223 women underwent ASC: 120 in ASC-T and 103 in ASC-M. The average age was 65.3 (±6.5) years in the ASC-T group and 65 (±8.5) years in the ASC-M group, with no difference between them (p=0.706). There was no difference in intraoperative increased bleeding (p=1.000) and bladder injury (p=0.706) in both groups. Comparing the POP-Q points pre- and postoperatively, we observed improvement in all points in both groups (p<0.001) without difference between them. The analysis of variance for repeated measures was used to compare the outcomes between the two groups. The postoperative prolapse stage was similar between the two groups in the apical (p=0.251) and anterior (p=0.052) vaginal compartments. In the subjective evaluation, we observed a high rate of cure and improvement in both groups, respectively 81.7% and 16.7% in the ASC-T group, and 91.3% and 8.7% in the ASC-M group (p=0.100).</p><p><strong>Conclusion: </strong>Both sacrocolpopexy techniques were effective in treating apical prolapse, as evidenced by both objective and subjective cure rates, with a low complication rate.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subsequent mammography reduces recall and increases breast cancer detection: an audit of a screening program.","authors":"Erika Marina Solla Negrao, Mariana Alves Almeida, Emanuele Françoso Cardoso, Alvaro Silva Almeida, Samanta Santos Sousa, Cassio Cardoso-Filho, Rodrigo Menezes Jales, Diama Bhadra Vale","doi":"10.61622/rbgo/2025rbgo89","DOIUrl":"10.61622/rbgo/2025rbgo89","url":null,"abstract":"<p><strong>Objective: </strong>To analyze recall rates in a public breast cancer screening facility in Campinas, Brazil.</p><p><strong>Methods: </strong>A prospective assessment of outcomes on screening mammographies (MMG) between July 2023 and August 2024. BI-RADS® 0,4/5 indicated positive results, and women recalled. The variables were age, whether first or subsequent MMG, and biopsy (cancer positive or negative). The outcomes were recall rate and cancer detection rate on the recall (CDR). Prevalence ratio with 95% confidence interval (PR) estimated the risk.</p><p><strong>Results: </strong>There were included 19,377 MMG on women over 40: 15,983 subsequent MMG (82.5%), and 1,646 women recalled (BR 0,4/5). Adherence to recall was over 99%. The recall rates were 12.4% at first and 7.7% at subsequent MMG. Recall rate was 1.6 times higher at first than at subsequent MMG (PR 1.61;1.45-1.79). CDR was higher at subsequent MMG. A first MMG reduced the risk of cancer detection by 71% (PR 0.29-0.15;0.58). Compared to women 50-69, there were no differences in the risks of recall and cancer detection at first MMG. At subsequent MMG the recall risk was higher in women 40-49 (PR 1.16;1.03-1.30), and over 69 (PR 1.47;1.03-2.12). The risk of cancer detection was 60% lower in women 40-49 (PR 0.60;0.36-0.99), and 2.7 times higher in women over 69 (PR 2.78;1.32-5.84).</p><p><strong>Conclusion: </strong>The recall rates were 12.4% at first and 7.7% at subsequent MMG. Adherence was high. Screening efficiency was higher in women 50-69. At subsequent screenings women 40-49 showed a higher recall rate and a lower CDR when compared to women 50-69.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in artificial intelligence for the early detection of cervical cancer in adult women: a scoping review.","authors":"Laura Vanesa Henao Ramírez, Hanna Eljach Forero, María Paula Novoa Grosso, Erwin Hernando Hernández Rincón","doi":"10.61622/rbgo/2025rbgo76","DOIUrl":"10.61622/rbgo/2025rbgo76","url":null,"abstract":"<p><strong>Objective: </strong>To synthesize current scientific evidence on the benefits and potential contributions of integrating AI-based technologies with traditional diagnostic methods used for the detection and early diagnosis of cervical cancer in adult women.</p><p><strong>Methods: </strong>An exhaustive search was conducted in academic databases (PubMed, Scopus and BIREME) using specific search terms and Boolean operators in December 2024. Independently conducted by three researchers across all databases, the selection process included articles involving adult women with either suspected or confirmed cervical cancer, in which the application of artificial intelligence (AI) technologies was examined across various techniques used for early diagnosis of the disease, such as cytology, colposcopy, and radiological imaging, among others. Only articles published between 1999 and 2022 were included. The included articles were reviewed in full text by all authors, and relevant data were extracted and organized into a chart comprising the following items: author and year of publication, title, study design, type of AI technology used, and a summary of the content.</p><p><strong>Results: </strong>AI, particularly through Machine Learning (ML) algorithms, demonstrated significant improvements in the accuracy, sensitivity, and efficiency of cervical lesion classification when combined with conventional diagnostic techniques like cervical cytology, colposcopy, and biopsy. This combined approach outperformed traditional methods used in isolation.</p><p><strong>Conclusion: </strong>The integration of AI with standard cervical cancer screening and diagnostic methods offers substantial benefits, including faster detection times, reduced workload for pathologists, and improved patient outcomes by facilitating earlier treatment initiation and reducing diagnostic variability. Considering the available literature, the use of AI may offer potential benefits; however, further studies are required.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: A new screening of preterm birth in gestation with short cervix after pessary plus progesterone.","authors":"Vittorio Unfer","doi":"10.61622/rbgo/2025rbgo98","DOIUrl":"10.61622/rbgo/2025rbgo98","url":null,"abstract":"","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145672473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newborn clavicle fractures: 5 year-review of a tertiary-care hospital.","authors":"Joana Rita Pinto Galvão, Mariana da Silva Leal, Margarida Neves Maciel da Silva, Nuno Miguel Sanches de Almeida, Carla Isabel Pereira Faustino Ferreira, Inês Maria Moreira Guedes Maia Nunes de Melo Seco","doi":"10.61622/rbgo/2025rbgo92","DOIUrl":"10.61622/rbgo/2025rbgo92","url":null,"abstract":"<p><strong>Objectives: </strong>Clavicle fractures are the most common birth-related fractures. They may cause pain, arm mobility impairment, and brachial nerve injury (temporary or definitive). Therefore, we aimed to review the incidence, risk factors and prognosis of neonatal clavicle fractures in our hospital.</p><p><strong>Methods: </strong>All cases of clavicle fractures diagnosed and registered during the neonatal period between 2018 and 2022, in a tertiary-care Portuguese hospital, were reviewed. Statistical descriptive analysis, odds ratios (ORs), and 95% confidence intervals(95%CI) were calculated.</p><p><strong>Results: </strong>A total of 8132 births and 91 clavicle fractures were identified (1.1% incidence) - 0.04% (1/2512) in cesarean sections and 1.7% (90/5453) in vaginal births. An instrumental vaginal birth doubled the probability of clavicle fractures (OR 2.072, 95%CI 1.365-3.145 compared to spontaneous births). In 15.4% of clavicle fractures, births were complicated by shoulder dystocia. Shoulder dystocia significantly increased the risk of clavicle fracture (OR 35.71; 95% CI 17.86-71.43). Of the 91 cases, 22% resulted from pregnancies complicated by gestational diabetes; in these cases, the risk of clavicle fractures increased 76% (OR 1.761, 95%CI 1.068-2.904). Most of the cases were referred to a Neonatology follow-up appointment (92.3%). Fifteen neonates had a clinical suspicion of brachial plexus injury, but all of them regained normal arm mobility after physiotherapy.</p><p><strong>Conclusion: </strong>The incidence of clavicle fractures in our hospital is comparable to the literature (1.1%). To reduce the incidence of clavicle fractures not only its risk factors must be reduced, but a simulation-based labor ward team training program on shoulder dystocia should also be implemented.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.","authors":"Gláucia Maria Moraes de Oliveira, Maria Cristina Costa de Almeida, Cynthia Melissa Valério, Fernando Giuffrida, Larissa Neto Espíndola, Maria Cristina de Oliveira Izar, Celi Marques-Santos, Claudia Maria Vilas Freire, Carlos Japhet da Matta Albuquerque, Antonio Carlos Pallandri Chagas, Dalton Bertolim Précoma, Evandro Tinoco Mesquita, José Francisco Kerr Saraiva, Maria Elizabeth Navegantes Caetano Costa, Viviana de Mello Guzzo Lemke, Alexandre Jorge Gomes de Lucena, Andréa Araujo Brandão, Antonio Aurelio de Paiva Fagundes, Ariane Vieira Scarlatelli Macedo, Carisi Anne Polanczyk, Cristiane Bauermann Leitão, Daniel Souto Silveira, Elaine Dos Reis Coutinho, Eliana Aguiar Petri Nahas, Elizabeth Regina Giunco Alexandre, Erika Maria Gonçalves Campana, Erika Olivier Vilela Bragança, Fernanda Marciano Consolim Colombo, Imara Correia de Queiroz Barbosa, Ivan Romero Rivera, Jaime Kulak, João Eduardo Nunes Salles, João Roberto de Sá, José Maria Soares, Larissa de Almeida Dourado, Lidia Zytynski Moura, Lucelia Batista Neves Cunha Magalhães, Luciano de Melo Pompei, Luiz Guilherme Passaglia, Marcelo Heitor Vieira Assad, Marcio Alexandre Hipólito Rodrigues, Maria Alayde Mendonça Rivera, Maria Antonieta Albanez Albuquerque de Medeiros Lopes, Maria Sanali Moura de Oliveira Paiva, Marildes Luiza de Castro, Milena Dos Santos Barros Campos, Olga Ferreira de Souza, Orlando Otávio de Medeiros, Rafaela Andrade Penalva Freitas, Regina Coeli Marques de Carvalho, Sheyla Cristina Tonheiro Ferro da Silva, Thais de Carvalho Vieira Rodrigues, Walkiria Samuel Avila, Wellington Santana da Silva, Willyan Issamu Nazima, Lucia Helena Simões da Costa-Paiva, Maria Celeste Osorio Wender","doi":"10.61622/rbgo/2025rbgo200","DOIUrl":"10.61622/rbgo/2025rbgo200","url":null,"abstract":"","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12674831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low adherence to aspirin and calcium carbonate for preeclampsia prevention in pregnant women with chronic hypertension in a brazilian hospital.","authors":"Bruno Verri Jardine, Priscila Oliveira Barbosa, Luiz Sérgio Lima-Júnior, Ranieri Andrade Alves, Taís Delazari de Carvalho, Samuel Luiz Nunes Santos, Ricardo Carvalho Cavalli","doi":"10.61622/rbgo/2025rbgo77","DOIUrl":"10.61622/rbgo/2025rbgo77","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate adherence to preeclampsia prophylaxis with aspirin and calcium carbonate among pregnant women with chronic hypertension attending a specialized hypertension in pregnancy center at a tertiary hospital in Brazil.</p><p><strong>Methods: </strong>A cross-sectional study was conducted at the Hospital das Clínicas de Ribeirão Preto. Adherence to aspirin and calcium carbonate was assessed using the Morisky-Green questionnaire. Additionally, we assessed the knowledge of these women regarding preeclampsia. A total of 101 pregnant women were interviewed, and 98 were included in the final analysis.</p><p><strong>Results: </strong>Non-adherence rates were 64.3% for aspirin and 59.2% for calcium carbonate. The overall incidence of preeclampsia was 22.4% with 11% requiring magnesium sulphate for blood pressure control. No significant differences in preeclampsia incidence were observed among adherent and non-adherent groups for either aspirin or calcium carbonate. Most participants demonstrated high (78.6%) or medium (18.4%) levels of knowledge about preeclampsia.</p><p><strong>Conclusion: </strong>There was low adherence to aspirin and calcium carbonate prophylaxis among pregnant women with chronic hypertension, with no difference in preeclampsia prevention between adherent and non-adherent groups. These findings raise important questions about the effectiveness of aspirin in reducing preeclampsia risk in chronic hypertension. Further studies should be conducted to evaluate the reasons for low adherence.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}