Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia最新文献

{"title":"Exploring endometriosis before surgical treatment: unraveling pain, sexual function and quality of life patterns.","authors":"Juliana Olavo Pereira, Jaime Kulak","doi":"10.61622/rbgo/2025rbgo47","DOIUrl":"10.61622/rbgo/2025rbgo47","url":null,"abstract":"<p><strong>Objective: </strong>To identify pain, sexual function, and quality of life patterns in women with endometriosis, taking into consideration the American Society for Reproductive Medicine (ASRM) classification for endometriosis.</p><p><strong>Methods: </strong>A cross-sectional study of quantitative descriptive nature was conducted, including women with surgical recommendation due to endometriosis. The Numeric Pain Rating Scale, Endometriosis Health Profile, and Female Sexual Function Index tools were used for data collection. Descriptive and frequency analysis were employed. Using the K-means algorithm, cluster analysis was performed to group participants based on response similarities.</p><p><strong>Results: </strong>104 women with endometriosis were included with a median age of 35 years. The majority were classified as grade III (57.69%) and IV (25.96%) for endometriosis. There was a significant difference in the division of two clusters concerning ASRM, with ASRM IV women more frequently associated with Cluster B, while Cluster A being predominantly formed by ASRM III women. Cluster B showed significantly worse data for dyspareunia and dysuria pain levels and for all variables in the FSFI and EHP-30 instruments, except for infertility, which did not differ between the groups.</p><p><strong>Conclusion: </strong>ASRM classification is not directly related to clustering. Women diagnosed with endometriosis, mostly ASRM III and IV, exhibit two distinct patterns, with one group having worse pain, sexual function and quality of life scores compared to the other group. Infertility is a crucial aspect to study concerning the quality of life of women living with the disease and aspiring for motherhood irregardless of the clustering.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leptin receptor polymorphism increases the risk of painful symptoms in Brazilian women with endometriosis.","authors":"Jéssica Vilarinho Cardoso, Daniel Escorsim Machado, Fernanda Nunes de Almeida, Plínio Tostes Berardo, Rui Medeiros, Jamila Alessandra Perini","doi":"10.61622/rbgo/2025rbgo43","DOIUrl":"10.61622/rbgo/2025rbgo43","url":null,"abstract":"<p><strong>Objective: </strong>Endometriosis pain is associated with inflammatory cytokines, such as leptin (LEP), through activation with its receptor (LEPR), and its expression can be influenced by the presence of genetic polymorphisms. Therefore, this study aims to evaluate the role of the <i>LEP</i> rs7799039 and <i>LEPR</i> rs1137100 polymorphisms in the painful symptoms of endometriosis in Brazilian women.</p><p><strong>Methods: </strong>A retrospective study was carried out in two Brazilian public hospitals with 237 cases of endometriosis, divided into two comparison groups according to the painful symptoms associated with the disease (absence or presence of severe and disabling symptoms). Genetic analysis was performed by real-time PCR technique, and association analyses were estimated using odds ratio (OR) and 95% confidence interval (CI), using a non-conditional logistic regression model.</p><p><strong>Results: </strong>Endometriosis cases showed a high prevalence of painful symptoms: 82% dysmenorrhea, 67% dyspareunia, 53% chronic pelvic pain, and 52% cyclical intestinal and 25% urinary complaints. Regarding genetic analyses, cases had 32.7% of the A allele and 11.4% of the AA genotype for the <i>LEP</i> rs7799039 G>A SNP, and 17.5% of the G allele and 2.5% for of GG genotype for the <i>LEPR</i> rs1137100 A>G SNP. There is a significant association of the <i>LEPR</i> rs1137100 polymorphism with chronic pelvic pain (OR=1.75; CI 95%=1.05-2.89) and dyspareunia (OR=1.78; CI 95%=1.01-3.12) in women with endometriosis.</p><p><strong>Conclusion: </strong>Our findings suggest that the <i>LEPR</i> rs1137100 polymorphism is associated with increased endometriosis-related gynecological pain and may be a potential target for molecular diagnosis of the disease and development of individualized treatment strategies.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voiding urodynamics parameters for women with and without symptomatic pelvic organ prolapse.","authors":"José Tadeu Carvalho Martins, Gisele Vissoci Marquini, Laura Aparecida Xavier de Abreu, Zsuzsanna Ilona Katalin de Jármy Di Bella, Marair Gracio Ferreira Sartori","doi":"10.61622/rbgo/2025rbgo52","DOIUrl":"10.61622/rbgo/2025rbgo52","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to characterize voiding urodynamics parameters suggestive of bladder outlet obstruction (BOO) diagnosis in women with and without symptomatic pelvic organ prolapse (POP).</p><p><strong>Methods: </strong>Cross-sectional research. Patients were selected and clinically evaluated with anamnesis, pelvic organ prolapse quantification system and standard Urodynamic Testing, performed according to International Continence Society and International Urogynecological Association guidelines (noninvasive uroflowmetry, followed by invasive cystometry and a Pressure/Flow Study). Included criteria: women aged 18 to 94 years with and without symptomatic POP and lower urinary tract symptoms . Exclusion criteria: patients who were not clinically feasible, undesirable, or impossible urodynamic test, or patients with urinary tract infection or neurological lower urinary tract dysfunction.</p><p><strong>Results: </strong>Voiding urodynamics parameters suggestive of BOO diagnosis found in women with POP were: maximum flow rate (Qmax) in the uroflowmetry ≤12mL/s; detrusor pressure at maximum flow (PdetQmax) >20cmH2O. When evaluating the differences between patients with and without POP, it was observed that those who presented some type of pPOP were mean age (y) older (67.6 × 58.9); had higher post-void residue volume (mL) (85.9 × 33.9); higher PdetQmax (cmH₂O) values (41.3 × 28.5); lower Qmax (mL/s) values on uroflowmetry (8.5 × 20.4), lower maximum cystometric capacity (mL) (325.7 × 381.2), lower bladder compliance (mL/cmH2O) (39.8 × 46.1) and lower Qmax (mL/cmH2O) in the flow/pressure study (8.4 × 18.0) (<i>p</i><0.001).</p><p><strong>Conclusion: </strong>The voiding urodynamics parameters listed in this study allows the evaluation of variables suggestive of BOO diagnosis in women with and without POP.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing reproductive health inequities in Brazil's open drug scenes: the case for improving uptake of etonogestrel subdermal implant.","authors":"Clarice Sandi Madruga, Katia Isicawa de Sousa Barreto, Danilo Seabra, André Miguel, Claudio Jerônimo da Silva, Guilherme Sabino de Godoy, Lidiane Nogueira Rebouças, Natália Alexandre Ferreira, Rogerio Adriano Bosso, Carmen Silvia Molleis Galego Miziara, Martha Canfield, Quirino Cordeiro, Ronaldo Ramos Laranjeira","doi":"10.61622/rbgo/2025rbgo60","DOIUrl":"10.61622/rbgo/2025rbgo60","url":null,"abstract":"","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different testosterone formulations discontinuation and dose spacing on hematocrit and testosterone levels in transgender individuals with erythrocytosis.","authors":"Sérgio Henrique Pires Okano, Silvio Antônio Franceschini, Luiz Gustavo Oliveira Brito, Lucia Alves da Silva Lara","doi":"10.61622/rbgo/2025rbgo35","DOIUrl":"10.61622/rbgo/2025rbgo35","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to compare the effect of Gender Affirming Hormone Therapy with Testosterone (GAHT-T) discontinuation and dose spacing on Hct, hemoglobin (Hb) and total testosterone levels in users of testosterone cypionate and testosterone undecanoate.</p><p><strong>Methods: </strong>This retrospective cohort analyzed data collected from the medical records of trans men older than 18 years who developed erythrocytosis during GAHT-T between 2020 and 2023. Participants were divided into three groups according to formulation in use when the diagnosis of erythrocytosis occurred and analyzed according to therapeutic approaches: discontinuation of GAHT-T for 3 months or, for the testosterone cypionate fourthly users, dose spacing.</p><p><strong>Results: </strong>A total of 49 trans men (mean age, 28.0 ± 7.8 years) were diagnosed with erythrocytosis, totalizing 104 tests. After discontinuing GAHT-T, a greater decrease in Hct, Hb and total T levels was observed in the testosterone cypionate (Cip 14 and Cip 28) users than in the testosterone undecanoate users (Und90). In Und90, discontinuation resulted in decrease of Hct and Hb levels, without difference in total T levels. Cip14 and Cip28 exhibited greater reductions in the Hct level than Und90 did with discontinuation. In Cip14, dose spacing had no effect on decreasing Hb, Hct and total T levels.</p><p><strong>Conclusion: </strong>Discontinuation of testosterone undecanoate for 3 months in trans men undergoing GAHT-T who had developed erythrocytosis reduces hemoglobin and hematocrit levels without a significant reduction in testosterone levels. Dose spacing in fortnightly testosterone cypionate users was not effective to reduce hematocrit and hemoglobin.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation and Cultural Adaptation of the Creighton Model FertilityCare™ System Follow-up Form to Brazilian Portuguese.","authors":"Carolina de Souza Delage Faria, Carla Ferreira Kikuchi Fernandes, José Maria Cordeiro Ruano, Marair Gracio Ferreira Sartori","doi":"10.61622/rbgo/2025rbgo48","DOIUrl":"10.61622/rbgo/2025rbgo48","url":null,"abstract":"<p><strong>Objective: </strong>To develop the Brazilian Portuguese version of the Follow-up Form for the Creighton Model FertilityCare™ System.</p><p><strong>Methods: </strong>Translation and cultural adaptation of the Follow-up Form for use in Brazil, in 6 steps: Translation, Expert Panel, Back-Translation, Pre-test, Review, and Final Version, according to the World Health Organization methodology.</p><p><strong>Results: </strong>The 25 sections comprising the Follow-up Form were translated with 14 sections undergoing an adaptation process in one of the stages. In order to maximize semantic, idiomatic, experiential, and conceptual equivalence of the items from the original English version to Portuguese. The need for adaptation was due to four reasons: first, the format of paired and seemingly repetitive questions. Second, the difference in cultural reality, such as hygiene and consumption habits, between the United States and Brazil. Third, the use of technical terms, medical vocabulary. And fourth, sentences that contain many concepts related to the use of the Creighton Model FertilityCare™ System. The sample included 127 Creighton Model FertilityCare™ System users, with an average age of 33.7 years, and 88.2% were married. The majority, 68 (53.5%), were not using any family planning method when they started Creighton Model FertilityCare™ System 49.2% were trying to conceive in the past year.</p><p><strong>Conclusion: </strong>The translation of the Follow-up Form into Brazilian Portuguese resulted in a final version that maintained the intercultural and conceptual equivalence to the original English version. This instrument can be used by all practitioners in Brazil with the assurance that the standardization in the application of Creighton Model FertilityCare™ System reflects the original purpose of the method.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 10-year cesarean section rate analysis in a Brazilian referral maternity hospital using the Robson's ten group classification system.","authors":"Maria Laura Alves de Melo Silva, José Paulo de Siqueira Guida, Giuliane Jesus Lajos, Maria Laura Costa, Adriana Gomes Luz","doi":"10.61622/rbgo/2025rbgo51","DOIUrl":"10.61622/rbgo/2025rbgo51","url":null,"abstract":"<p><strong>Objective: </strong>The Robson Ten Group Classification System categorizes women into groups based on obstetric characteristics. For each group there is a suggested cesarean section rate. Robson Ten Group Classification System allows for surveillance and evaluation of increasing cesarean section rate. This study aimed to evaluate deliveries in a Brazilian referral maternity hospital in the last decade using the Robson Ten Group Classification System.</p><p><strong>Methods: </strong>This was a retrospective cross-sectional study performed in a referral hospital, analyzing deliveries from January 2009 to August 2022. Women were classified into Robson's 10 groups based on electronic medical charts. Overall rates per year and cesarean section rate within each group were calculated and compared.</p><p><strong>Results: </strong>There was an increasing cesarean section rate over time (46.23% in 2009 vs 62.99% in 2022) in all groups. Groups 1-4, 5 and 10 had a significant increase. Among Groups 1-4 cesarean section rate increased from 34.06% to 38.59% (PR 1.132, CI 1.007-1.274), group 5 from 67.66% to 83.53% (PR 1.234, CI 1.151-1.323) and group 10 from 51.55% to 60% (PR 1.163, CI 1.017-1.332). In global analysis, groups 1-4 corresponded to 57.3% of included cases and its relative contribution to cesarean section rate was 31.6%, while group 5 represented 18.9% of cases and its relative contribution to cesarean section rate was 28.5%.</p><p><strong>Conclusion: </strong>Groups 1-4 and 5 contributed significantly to cesarean section rate in our analysis and group 10 (preterm birth) also had a major impact, considering the high risk setting. Cesarean section rate increased over time. Groups 1, 2, 5, and 10 contribute significantly to such an increase.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of vaginal laxity in primiparous women six months after birth.","authors":"Marina Resende Godoy, Gláucia Miranda Varella Pereira, Clara Vale Viegas, Marilene Vale de Castro Monteiro","doi":"10.61622/rbgo/2025rbgo61","DOIUrl":"10.61622/rbgo/2025rbgo61","url":null,"abstract":"<p><strong>Objective: </strong>To assess the prevalence of VL in primiparous women undergoing vaginal birth or caesarean section; and its association with obstetric, urinary, intestinal and sexual factors for its occurrence.</p><p><strong>Methods: </strong>This is a cross-sectional study carried out between July 2021 and January 2023. Primiparous women who underwent vaginal birth or caesarean section without complaints of VL during pregnancy were included. Clinical and obstetric data were collected and participants completed questionnaires on the impact of urinary incontinence (ICIQ-SF), vaginal symptoms (ICIQ-VS) and sexual distress (FSDS-R) at recruitment and six-months postpartum. Univariate and multivariate logistic regression was performed, considering VL as the outcome and p=0.05.</p><p><strong>Results: </strong>One hundred participants were included for data analysis. The prevalence of VL was 8%. In the univariate analysis, SUI, urgency urinary incontinence (UUI), coital incontinence, constipation and the ICIQ-VS and ICIQ-SF scores were associated with VL. The ICIQ-VS, FSDS-R and ICIQ-SF scores increased the risk of VL by one-fold. However, only UUI (OR 10.50(CI 95% 1.90-58.10), coital incontinence (OR 42.00(CI 95% 3.11-566.38), and ICIQ-VS (vaginal symptoms OR 1.32(CI 95% 1.05-1.66) and ICIQ-SF (OR 1.25(CI 95% 1.02-1.54), scores remained associated with VL in multivariate-analysis.</p><p><strong>Conclusion: </strong>The prevalence of VL in primiparous women was lower than that reported in other studies and showed an association with the occurrence of vaginal symptoms, UUI and coital incontinence, six- months postpartum.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual Quality of Life-Female (SQoL-F): Translation, cultural adaptation and validation of the Brazilian Portuguese version in postpartum women.","authors":"Dulciane Martins Vasconcelos Barbosa, Denise Nicodemo, Edmércia Holanda Moura, Silvania de Cassia Vieira Archangelo, Lydia Masako Ferreira, Daniela Francescato Veiga","doi":"10.61622/rbgo/2025rbgo32","DOIUrl":"10.61622/rbgo/2025rbgo32","url":null,"abstract":"<p><strong>Objective: </strong>Sexuality plays an important role in quality of life, and the postpartum period may negatively affect women's sexual function. This study aimed to translate, culturally adapt, and validate the Sexual Quality of Life - Female (SQoL-F) for use for use in Brazilian women in the postpartum period.</p><p><strong>Methods: </strong>The original version of the SQoL-F was translated and back translated by four independent sworn translators. A sample of 125 women in the late postpartum phase participated in the cultural adaptation (n=30) and convergent validation (n=95) phases. For the latter, the instrument was compared with the Brazilian version of the Female Sexual Function Index (FSFI). To assess reproducibility, 25 of the 95 women who participated in the validation phase completed the SQoL-F twice, at different times (two interviewers administered the SQoL-F, 15 to 20 days apart).</p><p><strong>Results: </strong>Cronbach's alpha was 0.905 (intraclass correlation=0.974; 95%CI: 0.943-0.988; p<0.001). Significant, moderate, positive correlations were observed between the SQoL-F score and the FSFI total score (r=0.572; p<0.001) and domains 'Desire' (r=0.502; p<0.001), 'Arousal' (r =0.576; p<0.001), and 'Satisfaction' (r=0.637; p<0.001). Excellent reproducibility was obtained for the SQoL-F score (intraclass correlation=0.974; 95%; CI: 0.943-0.988; p<0.001).</p><p><strong>Conclusion: </strong>The SQoL-F was adapted to the cultural context of Brazilian postpartum women, proved reproducible, and exhibited face, content, and construct validity.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The accuracy of the fullPIERS model in predicting adverse maternal and perinatal outcomes: evidence from a tertiary care maternity unit.","authors":"Iury Gomes, Franz Marçal, João Victor de Carvalho Reis, Ana Paula Dos Santos Silva, Lucas Sampaio, Leonardo Alves Moreira, Guilherme Lelis Costa, Mário Dias Correa, Zilma Silveira Nogueira Reis, Jussara Mayrink","doi":"10.61622/rbgo/2025rbgo39","DOIUrl":"10.61622/rbgo/2025rbgo39","url":null,"abstract":"<p><strong>Objective: </strong>Low- and middle-income countries face significant challenges in managing women diagnosed with pre-eclampsia, from making the clinical decision about whether to deliver to transferring these women to healthy facilities where they can receive appropriate care. The aim of this study was to evaluate the performance and accuracy of the fullPIERS model in a referral Brazilian maternity hospital - to assess maternal and fetal morbidity and impatient mortality at birth admission.</p><p><strong>Methods: </strong>A cross-sectional study analyzed pregnant women with preeclampsia diagnosis, between 2014 and 2023. The full PIERS model was applied to a database retrospectively collected and its accuracy to predict maternal and perinatal outcomes during the hospital stay was determined through a receiver operating curve.</p><p><strong>Results: </strong>Analyzing 207 pregnant women with fullPIERS had an Area Under the Curve (AUC) for adverse maternal outcome discrimination of 0.672 (0.576-0.767 95% CI, p<0.001) and AUC 0.582, (0.504-0.6661 95% CI, p = 0.041) for maternal and perinatal outcomes. Nevertheless, the model had no discrimination utility to assess perinatal outcomes (AUC 0.561, 0.480-0.642 95% CI, p = 0.642).</p><p><strong>Conclusion: </strong>The fullPIERS model had limited performance in identifying women at increased risk of adverse outcomes birth admission and absent utility to assess perinatal outcomes. Future studies, combining different tools and validated in low- and middle-income countries should be carried out to improve maternal health.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}