Challenges and recommendations of vaccination in immunosuppression.

•Address the types of immunodeficiency and the greater susceptibility to severe infections compared to the general population, as well as a less efficient response to vaccine stimuli. •Provide information on the negative impacts of infections on the health of immunodeficient individuals and their complications. •Provide knowledge of studies on the efficacy and safety of vaccines in the immunosuppressed population. •Clarify which vaccines should be indicated, the best time to administer them, and when to revaccinate. •Update gynecologists and obstetricians on the vaccination schedule for this population and on the position of the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) regarding the vaccines made available by the National Immunization Program, including by the Reference Centers for Special Immunobiologicals (Portuguese acronym: CRIEs) and private vaccination services.