Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia最新文献

{"title":"Cesarean delivery on maternal request in Brazil: an analysis based on the perceptions of survivors of the placenta accreta spectrum.","authors":"Bruna Molina Begalli, Silvana Maria Quintana, Alessandra Cristina Marcolin, Conrado Milani Coutinho, Geraldo Duarte, Marcos Masaru Okido","doi":"10.61622/rbgo/2025rbgo79","DOIUrl":"10.61622/rbgo/2025rbgo79","url":null,"abstract":"<p><strong>Objective: </strong>To analyze maternal request cesarean section (CDMR) through the perceptions of placenta accreta spectrum (PAS) survivors.</p><p><strong>Methods: </strong>This retrospective observational study was conducted at a university hospital, a reference center for the management of placenta accreta spectrum (PAS). Case identification was performed through a review of medical records, based on diagnoses related to placental disorders and postpartum hemorrhage. Only women who underwent puerperal hysterectomy between 2005 and 2023, with a PAS diagnosis confirmed by ultrasound conducted at the institution, were included. Eligible participants were contacted via instant messaging apps and invited to complete an online structured questionnaire, which included questions about their prior knowledge and post-event perceptions regarding cesarean delivery. Responses were compared between women in the cesarean delivery on maternal request (CDMR) group and those who underwent cesarean delivery for other indications.</p><p><strong>Results: </strong>A total of 89 cases of hysterectomy for PAS were identified during the study period. Of the 60 eligible women contacted, 41 responded to the questionnaire. Among them, 11 (26.8%) reported having requested the cesarean delivery, while 30 (73.2%) underwent the procedure for other reasons. It was found that 81.8% of women in the CDMR group had private health insurance, compared to 46.6% in the \"other indications\" group. High parity (≥3 pregnancies) was more common in the \"other indications\" group (80.0%) than in the CDMR group (36.4%). Overall, 36.6% were unaware of the risks of cesarean delivery, 48.8% did not receive adequate counseling during prenatal care, and 85.4% of participants were unaware of PAS. In the CDMR group, these values were 36.4%, 45.5%, and 72.7%, respectively. After the adverse experience, 51.2% of participants reported a change in their perception of cesarean delivery, 53.7% stated that they would have made a different choice if they had more information at the time, and 78.0% believed that the general population was unaware of the risks associated with cesarean delivery.</p><p><strong>Conclusion: </strong>The perceptions of women who experienced a \"near miss\" contributed to a better understanding of the process behind Brazilian women's preference for cesarean section. Decisions influenced by a pro-cesarean cultural context and misinformation tend to be poorly founded and more prone to regret. In Brazil, while CDMR is framed as an expression of autonomy, inadequate information and limited freedom can exacerbate inequalities, disproportionately affecting women in vulnerable situations.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145672402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Randomized clinical trial of vaginal microbiota in menopausal genitourinary syndrome using radiofrequency and topical estriol.","authors":"Ana Ximena Zunino, Priscila de Almeida Torre, Susana Cristina Aidé Viviani, Isabel Cristina Chulvis do Val Guimarães, Caroline Alves de Oliveira Martins, Douglas Guedes Ferreira, Luiza Oliveira Ribeiro, Faustino Ramón Pérez-López","doi":"10.61622/rbgo/2025rbgo85","DOIUrl":"10.61622/rbgo/2025rbgo85","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the vaginal microbiota before and after the treatment with vaginal microablative fractional radiofrequency (FRAXX) and compare it with topical estriol treatment in women with GMS.</p><p><strong>Methods: </strong>Pilot clinical trial, double-blind, randomized, and placebo-controlled. Thirty women diagnosed with SGM were evaluated regarding the vaginal microbiota before and one month after the end of the treatment protocol, through culture, bacterioscopy by Gram and pHmetry. Then, they were randomized into two groups: one with application of topical estriol for 21 days of attack and then 3 times a week until completing 3 months, together with placebo radiofrequency (RF) pulses, and the other group, with monthly radiofrequency pulses for 3 months, together with placebo vaginal cream.</p><p><strong>Results: </strong>The average age of participants was 56.33 ± 7.10 (minimum 42 and maximum 69 years of age), average age at onset of menopause 44.70 ± 5.74. In the estriol group, the participants showed no significant difference after treatment in relation to the number of basal and parabasal cells (p = 1.000), type of vaginal microbiota (p = 0.544), presence (or absence) of <i>Lactobacillus</i> (p = 1.000), presence (or absence) of <i>Coccobacillus</i> (p = 1.000), presence (or absence) of grouped or chained <i>Cocci</i> (p = 1.000), except for the presence of <i>Candida</i> (p = 0.025) and decrease in vaginal hydrogen potential (pH) (p = 0.006). In the group treated with FRAXX, it was observed that the participants showed no significant difference after treatment regarding the number of basal and parabasal cells (p = 0.500), type of vaginal microbiota (p = 0.637), presence (or absence) of <i>Lactobacillus</i> (p = 1.000), presence (or absence) of <i>Cocobacilli</i> (p = 1.000), presence (or absence) of grouped or chained <i>Cocci</i> (p = 1.000) and presence (or absence) of <i>Candida</i> (p = 1.000), except for pH variation (p = 0.037). Comparing the groups, women treated with FRAXX had a higher proportion of <i>Lactobacillus</i> (type I) than women treated with estriol (66.7% and 26.7%, respectively; p = 0.057). On the other hand, the proportional presence of other bacteria, but with a predominance of <i>Lactobacillus</i> (type II a) was higher in the group treated with estriol, when compared to the FRAXX group (46.6% and 6.7%, respectively; p = 0.057). And the application of estriol significantly increased the <i>Candida</i> concentration when compared to FRAXX (p = 0.042).</p><p><strong>Conclusion: </strong>There was improvement in the parameters analyzed regarding the vaginal microbiota in the intervention with FRAXX with a higher proportion of <i>Lactobacillus</i> and a decrease in pH. And there was no superiority of FRAXX in relation to the use of topical estriol.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12711237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Did COVID-19 impact perinatal outcomes differently in public and private maternity hospitals in Brazil?","authors":"Ellen Machado Arlindo, Renato Teixeira Souza, Maria Laura Costa, Jose Guilherme Cecatti, Edson Vieira da Cunha, Janete Vettorazzi","doi":"10.61622/rbgo/2025rbgo80","DOIUrl":"10.61622/rbgo/2025rbgo80","url":null,"abstract":"<p><strong>Objective: </strong>To compare maternal and perinatal outcomes in pregnant and postpartum women with severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) infection among admissions in public and private maternity hospitals before COVID-19 vaccination.</p><p><strong>Methods: </strong>We performed a secondary analysis of the REBRACO (in Portuguese, the Brazilian Network of COVID-19 During Pregnancy) initiative, a national multicenter cohort study in Brazil, considering pregnant and postpartum women with suspected or confirmed SARS-CoV-2 infections (from February 2020 to February 2021) in 15 maternity centers (2 private and 13 public facilities). Sociodemographic and obstetric characteristics were compared according to the type of hospital care. The clinical and laboratory findings and maternal and perinatal outcomes were compared between the two groups. The prevalence ratio and its 95% confidence interval for each predictor and outcome were calculated.</p><p><strong>Results: </strong>Of the 559 symptomatic cases tested, 289 confirmed COVID-19 cases were included, with 213 (72.7%) and 76 (27.3%) women in public and private hospitals, respectively. The frequency of SARS-CoV-2 infection did not differ significantly between the groups. Women treated at public hospitals had lower education levels (p<0.001), and 50% declared that their pregnancy was unplanned. We recorded 13 maternal deaths among women treated at public hospitals and no maternal deaths among pregnant women treated at private hospitals (p=0.024). Pregnant women in public hospitals had higher rates of fever (p=0.041), tachypnea (p=0.003), abnormal laboratory findings of liver enzymes (p=0.005), and severe acute respiratory syndrome (SARS) (p=0.014), and their neonates presented with more neonatal respiratory distress (p=0.020).</p><p><strong>Conclusion: </strong>Adverse maternal and perinatal outcomes were worse in the public hospital group, with increased rates of SARS and neonatal respiratory distress. The alarming difference in the number of deaths between patients treated in the public and private sectors highlights the urgency of better understanding the social determinants of health and calls the attention of leaders and policymakers to take action in mitigating their impact.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12671685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145672689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on: \"Relationship involving sexual function, distress symptoms of pelvic floor dysfunction, and female genital self-image\".","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.61622/rbgo/2025rbgo83","DOIUrl":"10.61622/rbgo/2025rbgo83","url":null,"abstract":"","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12711238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145783913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges and recommendations of vaccination in immunosuppression.","authors":"Caroline Alves de Oliveira Martins, Isabella Ballalai, Juarez Cunha, Susana Aidé","doi":"10.61622/rbgo/2025FPS7","DOIUrl":"10.61622/rbgo/2025FPS7","url":null,"abstract":"<p><p>•Address the types of immunodeficiency and the greater susceptibility to severe infections compared to the general population, as well as a less efficient response to vaccine stimuli. •Provide information on the negative impacts of infections on the health of immunodeficient individuals and their complications. •Provide knowledge of studies on the efficacy and safety of vaccines in the immunosuppressed population. •Clarify which vaccines should be indicated, the best time to administer them, and when to revaccinate. •Update gynecologists and obstetricians on the vaccination schedule for this population and on the position of the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) regarding the vaccines made available by the National Immunization Program, including by the Reference Centers for Special Immunobiologicals (Portuguese acronym: CRIEs) and private vaccination services.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurotrimin, a neural adhesion molecule, expression in early and advanced stage endometriosis.","authors":"Derya Iliman, Cihan Kaya, Sibel Kuras, Alev Kural, Murat Ekin, Levent Yasar","doi":"10.61622/rbgo/2025rbgo57","DOIUrl":"10.61622/rbgo/2025rbgo57","url":null,"abstract":"<p><strong>Objective: </strong>Endometriosis, a gynecological condition characterized by the presence of endometrial tissue outside the uterus, affects millions of women worldwide. This study aimed to investigate neurotrimin (NTM)'s expression, a glycerophosphatidylinositol-anchored neural adhesion molecule, in endometriotic lesions and eutopic endometrial tissue.</p><p><strong>Methods: </strong>In this laboratory based observational study NTM expression was measured in patients with early- and advanced-stage endometriosis and controls (patients without endometriosis who underwent gynecological surgery. Peritoneal endometriosis (peritoneum for controls) and eutopic endometrial tissue samples were collected from patients. Polymerase chain reaction and immunohistochemistry (IHC) were used to detect NTM in the tissue samples. Additionally, NTM levels in peripheral blood samples of all participants were measured using an enzyme-linked immunosorbent assay.</p><p><strong>Results: </strong>NTM mRNA and protein levels were significantly higher in the endometriotic foci of the stage 3-4 endometriosis group than in the control group (p<0.01). Stage 1-2 endometriotic foci showed significantly higher NTM IHC staining than the control group; however, no significant difference was found between the mRNA levels. Eutopic endometrial tissue from the stage 3-4 group had significantly higher NTM mRNA levels than the other groups. No significant difference was found between the control and stage 1-2 groups for eutopic tissue. Eutopic endometrial NTM IHC staining did not differ between groups. No significant difference was observed in peripheral blood NTM levels.</p><p><strong>Conclusion: </strong>This study found increased NTM expression, a neural adhesion molecule, especially in advanced endometriosis. The endometrial tissue of patients with early-stage endometriosis also showed increased NTM expression in ectopic locations but not in eutopic tissue.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of physical activity in women with polycystic ovary syndrome: a systematic review and meta-analysis.","authors":"Diana Carvalho Braga Cavalcante, Thalita Basso Scandolara, Gislaine Satyko Kogure, Cainã Rodrigues, Carolina Gennari Verruma, Manoel Odorico de Moraes, Rosana Maria Dos Reis, Marcelo Borges Cavalcante, Cristiana Libardi Miranda Furtado","doi":"10.61622/rbgo/2025rbgo56","DOIUrl":"10.61622/rbgo/2025rbgo56","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of aerobic and resistance exercise on body mass index (BMI), insulin levels, lipid profiles, and hormonal parameters in women with polycystic ovary syndrome (PCOS).</p><p><strong>Data sources: </strong>We searched PubMed, Web of Science, and Embase databases for publications up to September 2024. Fully published articles involving reproductive-age women diagnosed with PCOS were included.</p><p><strong>Study selection: </strong>Randomized controlled trials comparing supervised aerobic or resistance exercise to no intervention in women diagnosed with PCOS based on Rotterdam or NIH criteria were included. The Rayyan Systematic Review tool was used to organize study data.</p><p><strong>Data collection: </strong>Data extraction was conducted independently by two reviewers. Meta-analysis employed random-effects modeling.</p><p><strong>Data synthesis: </strong>Ten randomized controlled trials with 382 women were analyzed. Aerobic exercise interventions (12-24 weeks) reduced BMI, waist circumference, insulin levels, total cholesterol, and low-density lipoprotein. Effects on fasting glucose, high-density lipoprotein, and triglycerides varied. Hormonal assessments showed reduced testosterone and increased sex hormone-binding globulin in some studies. Resistance exercise improved lean body mass and reduced body fat percentage but showed minimal effects on hormonal parameters. Meta-analysis revealed aerobic exercise decreased insulin, cholesterol, and triglycerides compared to no intervention, while other metabolic and hormonal markers showed inconsistent changes.</p><p><strong>Conclusion: </strong>Aerobic and resistance exercise improve anthropometric measures, metabolic health, and hormonal balance in women with PCOS. These findings highlight exercise as a valuable therapeutic strategy for managing PCOS and enhancing overall health outcomes.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of auriculotherapy on labor pain severity and labor duration: a clinical trial.","authors":"Somayehsadat Eslami, Omolbanin Heydari, Moghaddameh Mirzaee, Zahra Shad, Firoozeh Mirzaee","doi":"10.61622/rbgo/2025rbgo33","DOIUrl":"10.61622/rbgo/2025rbgo33","url":null,"abstract":"<p><strong>Objective: </strong>Pain is an unavoidable reality of labor and the most noticeable determinant of the labor experience. The present study was conducted to assess the effect of auriculotherapy on labor pain and labor duration.</p><p><strong>Methods: </strong>This double blind, randomized, controlled clinical trial was conducted from 2021-2022 in Kerman, Iran. The sample consisted of 60 primiparous women assigned to an Intervention Group (<i>n</i> = 30) and a Control Group (<i>n</i> = 30). The study began after participants entered the active phase of labor at 37-40 weeks of pregnancy. In the Intervention Group, the researcher stimulated the desired points (uterus, pituitary gland, pelvis, cerebral, autonomous, sensory, endocrine gland, shen men, zero, external genitalia, and thalamus). Sham auriculotherapy (patches without seeds at the same acupoints) was done in the Control Group. Pain intensity in the two groups was recorded using the VAS before and after the intervention, when the cervix was dilated 4, 6, and 8 cm. Duration of labor was also recorded. Data were analyzed using SPSS 21 statistical software.</p><p><strong>Results: </strong>Pain intensity was significantly lower in the Intervention Group than in the sham Control Group (<i>P</i> < 0.0001) in different cervical dilatations after intervention. Compared to the sham Control Group, the intervention group was significantly different in the average duration of labor (<i>P</i> < 0.0001).</p><p><strong>Conclusions: </strong>Auriculotherapy was demonstrated to attenuate the severity of labor pains and expedite the labor duration. Hence, policymakers in this field are recommended to pay greater attention to this non-invasive method.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation, cross-cultural adaptation into Brazilian Portuguese and electronic migration of the WERF EPHect endometriosis patient questionnaire.","authors":"Gabriele Barbosa Anelli, Rafael Zucco de Oliveira, Juliana Meola, Daniela Michelazzo, Ricardo Perussi-E-Silva, Julio Cesar Rosa-E-Silva, Christian Becker, Nilufer Rahmioglu, Lone Hummelshoj, Stacey Missmer, Krina Zondervan, Omero Benedicto Poli-Neto","doi":"10.61622/rbgo/2025rbgo40","DOIUrl":"10.61622/rbgo/2025rbgo40","url":null,"abstract":"<p><strong>Objectives: </strong>To translate and cross-culturally adapt the standard version of the WERF EPHect EPQ into Brazilian Portuguese and migrate it to an electronic version using REDCap.</p><p><strong>Methods: </strong>The study included 120 women aged 18-50 years, with half completing the paper version and half the electronic version. The sample comprised 80 individuals with chronic pelvic pain (CPP), including 60 with endometriosis, recruited from a tertiary referral centre, and 40 women from a primary healthcare unit with no diagnosis of CPP or endometriosis. Illiterate or cognitively impaired individuals were excluded. The electronic migration was implemented in REDCap.</p><p><strong>Results: </strong>The Brazilian Portuguese EPQ-S demonstrated linguistic accuracy and cultural equivalence to the original English version. The paper version consisted of 35 pages, and 86.7% of respondents commented on its length. Despite this, it was well-received, although minor difficulties were observed among participants with lower education levels. The electronic version provided a more accessible experience, with a significantly shorter completion time (52.1 ± 13.2 minutes) compared to the paper version (70.9 ± 21.4 minutes). Both formats exhibited similar rates of missing data for questions related to symptoms and contraceptive use.</p><p><strong>Conclusion: </strong>This study successfully translated, adapted, and migrated the WERF EPHect EPQ-S into Brazilian Portuguese using REDCap. The findings underscore the linguistic and cultural challenges of such adaptations and highlight the electronic version's advantages in accessibility, efficiency, and participant satisfaction. This research supports the development of cross-cultural assessment tools for endometriosis research and healthcare delivery.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of serum markers of inflammation in endometrioma and benign ovarian cysts.","authors":"Arife Akay, Berna Dilbaz, Yaprak Engin-Üstün","doi":"10.61622/rbgo/2025rbgo58","DOIUrl":"10.61622/rbgo/2025rbgo58","url":null,"abstract":"<p><strong>Objective: </strong>Endometriosis is known as a chronic inflammatory disease. This study investigates the differences in the inflammatory response between endometriomas and benign ovarian cysts during the preoperative and postoperative periods.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients who underwent laparoscopic cystectomy for endometriomas or non-endometriotic benign cysts between 2010 and 2021. The study compared demographic and gynecological characteristics, lesion size, serum follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and preoperative and postoperative values of erythrocyte distribution width (RDW), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and leukocytes between the two groups.</p><p><strong>Results: </strong>The study included 116 patients (48.13%) in the Study Group and 125 (51.87%) in the Control Group. The mean age of the Study and Control Groups was 27.76 years and 24.54 years, respectively (p<0.001). A non-significant discrepancy in preoperative AMH and FSH values was observed between the two groups (p>0.05). Preoperative RDW (14.50±1.56 vs. 14.04±1.40), PLR (160.82±44.52 vs. 136.83±48.72), and NLR (2.60±1.10 vs. 2.17±1.13) were significantly higher in the Study Group (p<0.05). Nevertheless, only in the Study Group NLR exhibited a notable increase in the postoperative period (p<0.05). Preoperative NLR was positively correlated with cyst size in endometriomas but was not correlated with rASRM score, AMH, or FSH levels.</p><p><strong>Conclusion: </strong>The inflammatory markers RDW, PLR, and NLR were significantly elevated in endometriomas compared to other benign cysts during preoperative and postoperative periods. The inflammatory response increased with cyst size but was not related to ovarian reserve as measured by serum AMH or the stage of endometriosis.</p>","PeriodicalId":74699,"journal":{"name":"Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia","volume":"47 ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}