Michael-Luke Jones, Joseph K Britton, Nicholas D C Green, Ross D Pollock
{"title":"G-Induced Alterations of Consciousness in UK Military Aviation.","authors":"Michael-Luke Jones, Joseph K Britton, Nicholas D C Green, Ross D Pollock","doi":"10.3357/AMHP.6452.2026","DOIUrl":"10.3357/AMHP.6452.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Despite multiple risk mitigations, the adverse effects of +Gz acceleration on cerebral circulation continue to cause military aircraft incidents. A previous survey of Royal Air Force aircrew in 2012 reported that 37.2% had experienced at least one episode of G-induced alteration of consciousness. The aim of the present study was to determine whether the introduction of updated centrifuge training and improved countermeasures in training aircraft has reduced the prevalence of these incidents.</p><p><strong>Methods: </strong>An anonymous online survey of all UK Armed Forces pilots was carried out in 2023 to reassess the prevalence of G-induced alterations of consciousness and to investigate perceptions of G-related risk factors and mitigations in pilots exposed to the high-G environment.</p><p><strong>Results: </strong>Responses were received from 403 pilots, with a response rate of 11.9%. At least one incident of G-induced alteration of consciousness was reported by 21.6% of pilots. Frontline jet pilots reported a higher proportion of incidents compared to previous surveys, with more recent incidents involving the Eurofighter Typhoon than any other aircraft type (29.0% from 2015-2023, N = 38). Recency of +Gz exposure was rated as the most important factor affecting the risk of G-induced incidents.</p><p><strong>Discussion: </strong>An overall reduction in prevalence of G-induced alteration of consciousness incidents was observed, with frontline jet pilots reporting a higher proportion of incidents over time. The reported importance of high-G recency as a risk factor suggests that additional risk assessment for the G-layoff effect may be beneficial for UK frontline jet pilots. Jones M-L, Britton JK, Green NDC, Pollock RD. G-induced alterations of consciousness in UK military aviation. Aerosp Med Hum Perform. 2026; 97(4):257-263.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 4","pages":"257-263"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147525316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Norbert Guettler, David Holdsworth, Lysette Broekhuizen, Thomas Syburra, Joanna D'Arcy, Denis Bron, Olivier Manen, Eddie Davenport
{"title":"Cardiac Rhythm and Conduction Abnormalities in Aircrew.","authors":"Norbert Guettler, David Holdsworth, Lysette Broekhuizen, Thomas Syburra, Joanna D'Arcy, Denis Bron, Olivier Manen, Eddie Davenport","doi":"10.3357/AMHP.6678.2026","DOIUrl":"10.3357/AMHP.6678.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiac rhythm and conduction abnormalities are common findings in aircrew and are a frequent cause of a loss of flying privileges. Given the great variety of electrophysiological disorders, risk assessment is challenging for the aviation medical examiner. For aeromedical assessment, important aspects of an electrophysiological evaluation are the presence or absence of symptoms and prognosis of the arrhythmia. In young fit people with increased vagal tone, some abnormal electrocardiogram findings are acceptable and do not require further investigation.</p><p><strong>Case series: </strong>This article provides recommendations for a stepwise screening approach and enhanced investigation of rhythm and conduction abnormalities for those which increase the risk to flight safety. Four cases of common arrhythmias are presented, namely premature ventricular complexes, nonsustained ventricular tachycardia, supraventricular tachycardia, and atrial fibrillation. The most important factors for the aviation medical examiner regarding evaluation, treatment, and aeromedical assessment will be provided in a brief discussion of each case.</p><p><strong>Discussion: </strong>This paper presents the current benchmark for assessing aircrew with rhythm and conduction abnormalities with data derived from current aeromedical and clinical literature, as well as the expert consensus of the NATO Working Groups on Occupational Cardiology (HFM WG 251, 316). Guettler N, Holdsworth D, Broekhuizen L, Syburra T, D'Arcy J, Bron D, Manen O, Davenport E. Cardiac rhythm and conduction abnormalities in aircrew. Aerosp Med Hum Perform. 2026; 97(4):289-295.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 4","pages":"289-295"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147525336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"No Significant Effect of Mild Urinary Tract Infection-Like Symptoms on Psychomotor Vigilance.","authors":"Cammi Borden, Kaila A Vento","doi":"10.3357/AMHP.6787.2026","DOIUrl":"10.3357/AMHP.6787.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Aircrew reluctance to urinate during flights, coupled with the risk of urinary tract infections (UTIs), represents an under-explored occupational health issue. The effects of UTIs on aviation-relevant tasks are not well understood; however, they may lead to disruptions and distractions, potentially affecting aviators' flight safety.</p><p><strong>Methods: </strong>This observational study sought to investigate whether UTI-like symptoms impair psychomotor vigilance. A total of 38 healthy female subjects (N = 18 symptom group; N = 20 no symptom group) completed questionnaires and a 10-min Psychomotor Vigilance Task. Stepwise linear regression models (i.e., Model 1, primary symptoms; and Model 2, secondary symptoms) assessed whether symptom presence predicted reaction time, minor lapses, or major lapses. Additionally, independent t-tests were conducted on symptom severity/discomfort and performance to compare between groups.</p><p><strong>Results: </strong>Models 1 and 2 for the linear regression did not have a statistically significant explained variance; therefore, the models were a poor fit. The factors predicting psychomotor vigilance performance cannot be interpreted. Further, there were no significant differences in psychomotor vigilance metrics between the symptom and no symptom groups.</p><p><strong>Discussion: </strong>This study found no measurable impact of UTI-like symptoms on vigilance within the tested sample. However, UTIs remain a pertinent aeromedical concern affecting flight status and operational readiness. Proactive preventive medicine strategies, such as screening for a history of UTIs, are essential to reduce UTI incidence. While mild UTI symptoms may, under close clinical supervision, permit flight, prioritizing aircrew health and safety remain paramount. Borden C, Vento KA. No significant effect of mild urinary tract infection-like symptoms on psychomotor vigilance. Aerosp Med Hum Perform. 2026; 97(4):284-288.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 4","pages":"284-288"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147525318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards Digital Periodontology in Space Medicine.","authors":"Ruqaiyyah Siddiqui, Naveed Ahmed Khan","doi":"10.3357/AMHP.6830.2026","DOIUrl":"10.3357/AMHP.6830.2026","url":null,"abstract":"<p><strong>Background: </strong>During spaceflight, microgravity, radiation, and altered immune function can disrupt balance, increasing susceptibility to both oral and systemic inflammation. We propose a periodontal digital twin, a computational model that integrates oral microbiome, immune, and metabolic data to simulate individual health in real time. The proposed framework conceptualizes a data-driven model linking multiomic and physiological inputs from astronauts to personalized simulations of oral ecosystem dynamics. By continuously updating with new biological and environmental data, the digital twin can predict early deviations from homeostasis. A periodontal digital twin could function as an early warning system for immune dysregulation and microbial imbalance during long-duration missions, supporting targeted preventive or therapeutic interventions. Beyond its application to astronaut health, this approach provides a new lens to study host-microbe coadaptation and establishes a foundation for precision and predictive healthcare in both terrestrial and extraterrestrial contexts. Siddiqui R, Khan NA. Towards digital periodontology in space medicine. Aerosp Med Hum Perform. 2026; 97(4):300-302.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 4","pages":"300-302"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147525217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Initial Head-Neck Posture Affects Neck Injury Risk in Pilot Emergency Ejection.","authors":"Cheng-Fei Du, Xiao-Yang Zhang, Hua Zhao, Song-Yang Liu, Tian-Cheng Li, Xiao-Wang Wang, Kun-Tao Zhou","doi":"10.3357/AMHP.6751.2026","DOIUrl":"10.3357/AMHP.6751.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Neck injuries are commonly sustained during emergency aircraft ejections, with head-neck posture identified as a critical factor influencing injury risk. Despite this, the relationship between the initial head-neck posture and neck injury during emergency ejection has not been comprehensively studied. The objective of the present study was to investigate the effects of head-neck postures on the dynamic neck response of pilots during ejection.</p><p><strong>Methods: </strong>Using the Total Human Model for Safety, simulations were conducted involving four initial postures (i.e., rotation, flexion, extension, and lateral bending), each set at 15°, and four initial rotation angles (0°, 15°, 30°, 45°). Ejection acceleration curves were also simulated to the T1 vertebra and its inferior segments.</p><p><strong>Results: </strong>Neutral posture poses no risk of injury. In all the non-neutral postures (15°), only the rotation of 15° may cause risk of neck injury, and notably, this risk increases as the rotational angle increases.</p><p><strong>Discussion: </strong>Initial head-neck posture markedly influences cervical loading and injury risk during ejection. Axial rotation presents the greatest risk by elevating vertebral stress and ligament tension, emphasizing the critical importance of maintaining a neutral posture to protect the cervical spine during pilot ejection. Du C-F, Zhang X-Y, Zhao H, Liu S-Y, Li T-C, Wang X-W, Zhou K-T. Initial head-neck posture affects neck injury risk in pilot emergency ejection. Aerosp Med Hum Perform. 2026; 97(3):145-150.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"145-150"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jia Hao Alvin Woo, Ross D Pollock, Brian See, Shawn W Y Lim
{"title":"Electromyography vs. Foot Pedal Force Assessment During High-G Centrifuge Qualification Testing.","authors":"Jia Hao Alvin Woo, Ross D Pollock, Brian See, Shawn W Y Lim","doi":"10.3357/AMHP.6826.2026","DOIUrl":"10.3357/AMHP.6826.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Traditional assessment of the anti-G straining maneuver through foot pedal force measurements has limitations in capturing muscle engagement. This study evaluated surface electromyography (EMG) as an alternative tool during routine centrifuge qualification.</p><p><strong>Methods: </strong>There were 19 aircrew trainees who underwent centrifuge testing with concurrent EMG monitoring of 4 muscle groups and pedal force measurements during gradual onset runs and rapid onset runs. EMG data from lower limb and abdominal muscles were compared with pedal forces to assess correlation and timing differences across acceleration profiles.</p><p><strong>Results: </strong>EMG-pedal correlations were limited and profile dependent. Only right pedal force demonstrated consistent correlation with right vastus medialis activity across profiles (gradual onset: r = 0.756; rapid onset +6 Gz: r = 0.620; rapid onset +8 Gz: r = 0.463). No significant correlations were observed between pedal forces and hamstring or abdominal muscle activity. Duration analysis showed systematic differences, with right pedal force duration (46.36 ± 17.92 s) exceeding both rectus abdominis (28.98 ± 17.27 s) and vastus medialis activation (38.35 ± 14.90 s) during gradual onset runs. Rectus abdominis activation remained consistently lower than other muscles during rapid onset high-G exposure, reaching 48.67 ± 20.45% maximum voluntary contraction at +8 Gz compared with 72.28-82.56% in other groups.</p><p><strong>Discussion: </strong>EMG provides more comprehensive assessment than pedal force alone, delineating muscle activation patterns and timing differences that conventional methods cannot detect. The profile-dependent correlations and duration discrepancies highlight limitations of foot pedal measurements. These findings support incorporating EMG into routine centrifuge qualification to improve assessment accuracy and enable more targeted training interventions. Woo JHA, Pollock RD, See B, Lim SWY. Electromyography vs. foot pedal force assessment during high-G centrifuge qualification testing. Aerosp Med Hum Perform. 2026; 97(3):204-209.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"204-209"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathryn A Feltman, Jordayne Wilkins, Isaiah Persson, Spencer Stonehouse
{"title":"Neurophysiological Measures to Detect Spatial Disorientation.","authors":"Kathryn A Feltman, Jordayne Wilkins, Isaiah Persson, Spencer Stonehouse","doi":"10.3357/AMHP.6736.2026","DOIUrl":"10.3357/AMHP.6736.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Maintaining spatial orientation in flight remains a critical aspect of aviation safety. Monitoring an aviator's neurophysiological patterns may provide insight and opportunity to mitigate loss of spatial orientation. However, few studies have examined the utility of such measures. The purpose of the current study was to conduct a scoping review to document the research activities that have examined neurophysiological measures in relation to spatial orientation.</p><p><strong>Methods: </strong>Four databases were searched for literature using neurophysiological measures in studies assessing disorientation. The initial search yielded 110,135 articles. After removing duplicates and articles not meeting criteria, nine articles were reviewed.</p><p><strong>Results: </strong>One of the nine articles used an aviation-relevant task. From the nine articles, evidence suggested roles of the parietal and frontal lobes maintaining orientation. Regarding the aviation-relevant task, the frontal lobe was supported for its involvement in the experience of unidentified spatial disorientation. Across all, the frontal lobe was consistently implicated (support from six studies) for its role in orientation. However, the studies differed in neurophysiological measures and outcomes evaluated. Electroencephalography emerged as a potential candidate for detecting disorientation, with six studies using it as the neurophysiological measurement device.</p><p><strong>Discussion: </strong>Although the literature is limited on aviation-relevant tasks, there is strong support for activation patterns in the parietal and frontal lobes for orientation. This provides a starting point for experimental studies to further capture what patterns can be detected from neurophysiology when disorientation is experienced. Further research on aviation applications and using consistent measures is needed to further develop this area of research. Feltman KA, Wilkins J, Persson I, Stonehouse S. Neurophysiological measures to detect spatial disorientation. Aerosp Med Hum Perform. 2026; 97(3):194-203.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"194-203"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael J Boyle, Michael Pohlen, Kris Lehnhardt, Prashant Parmar, Benjamin Easter
{"title":"X-Ray and Ultrasound for Human Spaceflight Using the NASA IMPACT Conditions List.","authors":"Michael J Boyle, Michael Pohlen, Kris Lehnhardt, Prashant Parmar, Benjamin Easter","doi":"10.3357/AMHP.6649.2026","DOIUrl":"10.3357/AMHP.6649.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Imaging is central to modern clinical medicine and advancing the level of care on exploration-class missions will require imaging capabilities to reduce medical risk. The NASA Informing Mission Planning via Analysis of Complex Tradespaces (IMPACT) tool suite was designed for exploration-class mission probabilistic risk assessment and trade space analysis. The associated IMPACT Conditions List includes 119 in-flight medical conditions of high likelihood and/or consequence as established by flight and terrestrial data, as well as expert opinion. This study evaluates the utility of ultrasound (US) and radiography (XR) for these conditions.</p><p><strong>Methods: </strong>For each condition, two reviewers performed a rapid review of professional society guidelines and scientific literature, supplemented with subject-matter expertise, to semiquantitatively score the utility of US and XR for both diagnosis and management.</p><p><strong>Results: </strong>XR was diagnostically highly useful in 36 conditions and US in 38 conditions. Conversely, for 63 (52.9%) conditions, neither XR nor US had any diagnostic utility. For management, XR was highly useful for 24 conditions, while US was highly useful for 21.</p><p><strong>Discussion: </strong>In over one-third of conditions, XR possesses unique capabilities either complementary or superior to US. XR possesses superior diagnostic utility for bony injuries, dental conditions, and some pulmonary conditions, and superior management capability for orthopedic reductions and device placement confirmation. This analysis suggests future missions may consider augmenting the medical system with portable radiography if resource constraints allow, and future work should quantify the risk reduction provided by this capability. Boyle MJ, Pohlen M, Lehnhardt K, Parmar P, Easter B. X-ray and ultrasound for human spaceflight using the NASA IMPACT conditions list. Aerosp Med Hum Perform. 2026; 97(3):176-184.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"176-184"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cold Protection and Manual Performance Assessment of Aircrew Gloves.","authors":"Andrew S Weller, Jonathan W R Boyd","doi":"10.3357/AMHP.6701.2026","DOIUrl":"10.3357/AMHP.6701.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Military aircrew of rotary-wing aircraft often report cold and dysfunctional hands during cold-weather flying. Therefore, the cold protection and manual performance of in-service gloves was quantified in a laboratory study to support cold-weather advice to aircrew and glove procurement activities.</p><p><strong>Methods: </strong>There were 8 civilian men who undertook a 60-min thermal test simulating the metabolic cost of rear crew physical tasks and wearing representative clothing on 15 occasions, where 3 main glove types (Cape leather, C; Cape + silk liner, C + S; Gunner, G) and 5 air temperatures (TA; +20, +10, 0, -10, -20°C) were assessed. Physiological (including mean finger skin temperature, TFSK), subjective thermal, and manual performance (including bare-hand and gloved finger/hand dexterity) measures were obtained.</p><p><strong>Results: </strong>At a TA of 0°C, mean TSKF was 15.2 (C), 17.9 (C + S), and 22.4°C (G). Finger cold discomfort occurred at a TA of 0°C in C, and at -10°C in C + S and G. Gloved finger/hand dexterity was impaired relative to bare hands by 46/4 (C), 56/14 (C + S), and 73/44% (G). There was no relationship between TSKF and dexterity performance.</p><p><strong>Discussion: </strong>The performance of aircrew gloves has been baselined for male aircrew. Cape leather gloves are limited to a TA of +10°C. Adding silk liners and wearing the Gunner glove extended exposure down to a TA of 0°C but imposed considerable impairment on dexterity performance. Solutions are required to enhance cold protection at a lower cost to manual performance, which must demonstrate applicability to both male and female aircrew. Weller AS, Boyd JWR. Cold protection and manual performance assessment of aircrew gloves. Aerosp Med Hum Perform. 2026; 97(3):160-168.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"160-168"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michal A Kurek, Filip Kwiatkowski, Dariusz Popiela, Marcin Biernacki, Agata Gaździńska, Magdalena Rola
{"title":"Glycated Hemoglobin vs. Fasting Glucose in Routine Screening of Military Aircrew.","authors":"Michal A Kurek, Filip Kwiatkowski, Dariusz Popiela, Marcin Biernacki, Agata Gaździńska, Magdalena Rola","doi":"10.3357/AMHP.6755.2026","DOIUrl":"10.3357/AMHP.6755.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes screening is crucial in aviation medicine because of its impact on flight safety. This study compared the diagnostic performance of fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) in Polish Air Force pilots ages 45 yr and older and assessed their role in optimizing screening protocols. Additionally, the study examined the relationships between age, body mass index (BMI), body fat percentage, and prediabetes or diabetes prevalence in this population.</p><p><strong>Methods: </strong>This study included 175 military flight personnel who were undergoing periodic medical examinations. Individuals with diagnosed diabetes were excluded. FPG, HbA1c, age, BMI and body fat percentage were measured. A multivariate regression model was used to examine their associations.</p><p><strong>Results: </strong>Among 175 male pilots ages 45-60 yr (M = 50.05, SD = 3.74), 68.6% had normal HbA1c, 30.3% were prediabetic, and 1.1% were diabetic. FPG classified 43.4% of the subjects as normal, 53.1% as prediabetic, and 3.4% as diabetic. A normal BMI was found in 23.4% of the subjects, whereas a normal body fat percentage occurred in 37%. Regression revealed that body fat percentage was more strongly associated with HbA1c than was age or BMI.</p><p><strong>Discussion: </strong>HbA1c testing has proven to be a practical and cost-effective tool for detecting abnormal glucose metabolism in military aircrew, particularly when used alongside FPG. Its implementation has reduced the need for further testing and may streamline periodic evaluations. Additionally, body fat percentage emerged as a more reliable predictor of dysglycemia than BMI was, suggesting the value of including body composition assessments in routine screenings. Kurek MA, Kwiatkowski F, Popiela D, Biernacki M, Gaździńska A, Rola M. Glycated hemoglobin vs. fasting glucose in routine screening of military aircrew. Aerosp Med Hum Perform. 2026; 97(3):169-175.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"169-175"},"PeriodicalIF":0.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}