Aerospace medicine and human performance最新文献

{"title":"Space Radiation Effects on the Glutathione Redox Cycle and Cataract Formation.","authors":"Blake Douglas Katsev, Ryung Lee, Ji Hyun Kim, Arnold Leigh, Joshua Ong, Ethan Waisberg, Aaron J Lacy, Thomas H Mader, C Robert Gibson, John Berdahl, Andrew G Lee","doi":"10.3357/AMHP.6809.2026","DOIUrl":"https://doi.org/10.3357/AMHP.6809.2026","url":null,"abstract":"<p><strong>Introduction: </strong>With increasingly ambitious space ventures, astronauts face numerous hazards, including radiation, isolation, altered gravity fields, and hostile environments. Cataracts pose a significant challenge to astronauts' health and performance, both in space and upon returning to Earth. These concerns intensify with deep space exploration, where exposure to high-energy ionizing radiation in the form of galactic cosmic rays, solar particle events, and heavy ions accelerate cataract development.</p><p><strong>Methods: </strong>This review synthesizes research from Embase, Google Scholar, Web of Science, Grey Literature, PubMed, and NASA sources on cataracts, radiation, and spaceflight.</p><p><strong>Results: </strong>Of 3308 articles identified, 595 duplicates were removed, 476 met inclusion criteria, and 392 were included in the analysis.</p><p><strong>Discussion: </strong>Radiation-induced cataract pathophysiology consists of ionizing radiation induced oxidative stress, which increases free radicals while depleting glutathione. Glutathione is a key antioxidant that interacts with ascorbic acid to protect the lens. Once glutathione levels are compromised, oxidative damage promotes protein aggregation and opacification of the lens, resulting in cataract formation. Countermeasures include optimizing antioxidant defenses, intraocular lens placement, and implementing operational and biomedical strategies such as radiation shielding and protective eyewear. Understanding and addressing these risks is essential for ensuring astronaut visual health and mission success in prolonged space exploration. Katsev BD, Lee R, Kim JH, Leigh A, Ong J, Waisberg E, Lacy AJ, Mader TH, Gibson CR, Berdahl J, Lee AG. Space radiation effects on the glutathione redox cycle and cataract formation. Aerosp Med Hum Perform. 2026; 97(5):354-361.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 5","pages":"354-361"},"PeriodicalIF":0.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Bistable Perception Stability and Performance in Simulated Flight Operations.","authors":"Xue Zhang, Lin Wei, Xiuyi Li, Yuchuan Luo, Jiajun Yuan, Qilong Tan, Haiying Mu","doi":"10.3357/AMHP.6739.2026","DOIUrl":"https://doi.org/10.3357/AMHP.6739.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Bistable perception, where the brain alternates between two interpretations of ambiguous stimuli, has individual-specific switching rates. Although it is related to neural activities, no prior research has investigated its correlation with external behavioral performance. This study aimed to explore the relationship between the stability of bistable perception and behavioral performance, and the corresponding application prospects in the selection of special talents, such as pilots.</p><p><strong>Methods: </strong>We chose to use simulated flight operations in this research. Two experiments were conducted on ab initio pilot cadets. In Experiment 1, 38 cadets completed a simulated flight and then observed a bistable point-light rotating sphere (with or without rhythmic information) and reported its rotation direction. Experiment 2 involved 54 cadets divided into two groups observing either rhythmic or nonrhythmic spheres, with pre- and postflight tests.</p><p><strong>Results: </strong>The perceptual switch rate of the rotating sphere was negatively correlated with simulated flight scores (rhythmic: r = -0.547; nonrhythmic: r = -0.484). After observing three sessions of 3-min trials of rhythmic stimuli, the perceptual switch rate increased, which led to an increase in the dominant frequency of flight altitude fluctuations (t = 2.440).</p><p><strong>Discussion: </strong>Bistable perception stability can predict the performance of external behaviors in simulated flight. The change of perception stability will change operational stability. This research provides support for the application of bistable rhythmic rotating spheres in assessing the perceptual stability of flight candidates in pilot selection, and for enhancing the perceptual stability of pilot cadets in flight training. Zhang X, Wei L, Li X, Luo Y, Yuan J, Tan Q, Mu H. The association between bistable perception stability and performance in simulated flight operations. Aerosp Med Hum Perform. 2026; 97(5):337-343.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 5","pages":"337-343"},"PeriodicalIF":0.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Patterns of U.S. Navy Personnel Transitioning from Training to Fleet Assignments.","authors":"Nita Lewis Shattuck, Panagiotis Matsangas","doi":"10.3357/AMHP.6732.2026","DOIUrl":"https://doi.org/10.3357/AMHP.6732.2026","url":null,"abstract":"<p><strong>Introduction: </strong>It is often assumed that the sleep received by military personnel when they are in training is better than that they receive in their fleet assignments. The current study assessed this assumption.</p><p><strong>Methods: </strong>Using wearable devices, this prospective naturalistic study monitored the sleep patterns of 99 fit-for-duty (median age = 38 yr; 91 males) U.S. Navy surface warfare officers for a median of 340 d per subject. Data were collected while the subjects attended standardized training in a shore-based facility and during their follow-on fleet assignments.</p><p><strong>Results: </strong>Subjects slept on average 6.79 ± 0.578 h/d (64.7% slept on average <7 h/d and 6.06% slept <6 h/d). Sleep deprivation was evident in both environments but was more pronounced in the fleet assignment. Subjects slept more on weekends (+0.54 h/d in training and +0.84 h/d in fleet assignment); however, this extra sleep was not enough to account for the sleep loss during weekdays. In addition, sleep patterns were more irregular in the fleet. For subjects' major sleep episodes, heart rate, lowest heart rate, respiratory rate, and respiratory rate variability were higher in training. Sleep efficiency and heart rate variability did not differ between the two settings.</p><p><strong>Discussion: </strong>Our results shed light on the differences in sleep patterns and cardiac/respiratory activity indices between a training environment and fleet assignments. Daily sleep duration and sleep regularity are better in a training environment. The changes we identified in cardiac activity, respiration, and sleep efficiency need to be further assessed by focusing more closely on sleep stages. Shattuck NL, Matsangas P. Sleep patterns of U.S. Navy personnel transitioning from training to fleet assignments. Aerosp Med Hum Perform. 2026; 97(5):327-332.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 5","pages":"327-332"},"PeriodicalIF":0.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Demographic Makeup of Aerospace Medicine Specialists.","authors":"Andrew Z Lam","doi":"10.3357/AMHP.6084.2026","DOIUrl":"https://doi.org/10.3357/AMHP.6084.2026","url":null,"abstract":"<p><strong>Introduction: </strong>The flying population is diversifying, but the demographic composition of aerospace medicine specialists remains understudied. Nevertheless, comparing figures on the racial, ethnic, and gender makeup of pilots and astronauts with analog data from preventive medicine physicians and recent aerospace medicine residents reveals that certain minority groups served by aerospace medicine are likely underrepresented among aerospace medicine practitioners. Arguments regarding the potential advantages and challenges of diversity in aerospace medicine are presented, accompanied by supporting examples and research. Regardless of how its constituency ultimately decides to address the issue of diversity, an accurate collection of demographic data would provide the aerospace medicine profession with the information required for an evidence-based approach. Lam AZ. The demographic makeup of aerospace medicine specialists. Aerosp Med Hum Perform. 2026; 97(5):389-391.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 5","pages":"389-391"},"PeriodicalIF":0.9,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electromyography vs. Foot Pedal Force Assessment During High-G Centrifuge Qualification Testing.","authors":"Jia Hao Alvin Woo, Ross D Pollock, Brian See, Shawn W Y Lim","doi":"10.3357/AMHP.6826.2026","DOIUrl":"10.3357/AMHP.6826.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Traditional assessment of the anti-G straining maneuver through foot pedal force measurements has limitations in capturing muscle engagement. This study evaluated surface electromyography (EMG) as an alternative tool during routine centrifuge qualification.</p><p><strong>Methods: </strong>There were 19 aircrew trainees who underwent centrifuge testing with concurrent EMG monitoring of 4 muscle groups and pedal force measurements during gradual onset runs and rapid onset runs. EMG data from lower limb and abdominal muscles were compared with pedal forces to assess correlation and timing differences across acceleration profiles.</p><p><strong>Results: </strong>EMG-pedal correlations were limited and profile dependent. Only right pedal force demonstrated consistent correlation with right vastus medialis activity across profiles (gradual onset: r = 0.756; rapid onset +6 Gz: r = 0.620; rapid onset +8 Gz: r = 0.463). No significant correlations were observed between pedal forces and hamstring or abdominal muscle activity. Duration analysis showed systematic differences, with right pedal force duration (46.36 ± 17.92 s) exceeding both rectus abdominis (28.98 ± 17.27 s) and vastus medialis activation (38.35 ± 14.90 s) during gradual onset runs. Rectus abdominis activation remained consistently lower than other muscles during rapid onset high-G exposure, reaching 48.67 ± 20.45% maximum voluntary contraction at +8 Gz compared with 72.28-82.56% in other groups.</p><p><strong>Discussion: </strong>EMG provides more comprehensive assessment than pedal force alone, delineating muscle activation patterns and timing differences that conventional methods cannot detect. The profile-dependent correlations and duration discrepancies highlight limitations of foot pedal measurements. These findings support incorporating EMG into routine centrifuge qualification to improve assessment accuracy and enable more targeted training interventions. Woo JHA, Pollock RD, See B, Lim SWY. Electromyography vs. foot pedal force assessment during high-G centrifuge qualification testing. Aerosp Med Hum Perform. 2026; 97(3):204-209.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"204-209"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial Head-Neck Posture Affects Neck Injury Risk in Pilot Emergency Ejection.","authors":"Cheng-Fei Du, Xiao-Yang Zhang, Hua Zhao, Song-Yang Liu, Tian-Cheng Li, Xiao-Wang Wang, Kun-Tao Zhou","doi":"10.3357/AMHP.6751.2026","DOIUrl":"10.3357/AMHP.6751.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Neck injuries are commonly sustained during emergency aircraft ejections, with head-neck posture identified as a critical factor influencing injury risk. Despite this, the relationship between the initial head-neck posture and neck injury during emergency ejection has not been comprehensively studied. The objective of the present study was to investigate the effects of head-neck postures on the dynamic neck response of pilots during ejection.</p><p><strong>Methods: </strong>Using the Total Human Model for Safety, simulations were conducted involving four initial postures (i.e., rotation, flexion, extension, and lateral bending), each set at 15°, and four initial rotation angles (0°, 15°, 30°, 45°). Ejection acceleration curves were also simulated to the T1 vertebra and its inferior segments.</p><p><strong>Results: </strong>Neutral posture poses no risk of injury. In all the non-neutral postures (15°), only the rotation of 15° may cause risk of neck injury, and notably, this risk increases as the rotational angle increases.</p><p><strong>Discussion: </strong>Initial head-neck posture markedly influences cervical loading and injury risk during ejection. Axial rotation presents the greatest risk by elevating vertebral stress and ligament tension, emphasizing the critical importance of maintaining a neutral posture to protect the cervical spine during pilot ejection. Du C-F, Zhang X-Y, Zhao H, Liu S-Y, Li T-C, Wang X-W, Zhou K-T. Initial head-neck posture affects neck injury risk in pilot emergency ejection. Aerosp Med Hum Perform. 2026; 97(3):145-150.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"145-150"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"X-Ray and Ultrasound for Human Spaceflight Using the NASA IMPACT Conditions List.","authors":"Michael J Boyle, Michael Pohlen, Kris Lehnhardt, Prashant Parmar, Benjamin Easter","doi":"10.3357/AMHP.6649.2026","DOIUrl":"10.3357/AMHP.6649.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Imaging is central to modern clinical medicine and advancing the level of care on exploration-class missions will require imaging capabilities to reduce medical risk. The NASA Informing Mission Planning via Analysis of Complex Tradespaces (IMPACT) tool suite was designed for exploration-class mission probabilistic risk assessment and trade space analysis. The associated IMPACT Conditions List includes 119 in-flight medical conditions of high likelihood and/or consequence as established by flight and terrestrial data, as well as expert opinion. This study evaluates the utility of ultrasound (US) and radiography (XR) for these conditions.</p><p><strong>Methods: </strong>For each condition, two reviewers performed a rapid review of professional society guidelines and scientific literature, supplemented with subject-matter expertise, to semiquantitatively score the utility of US and XR for both diagnosis and management.</p><p><strong>Results: </strong>XR was diagnostically highly useful in 36 conditions and US in 38 conditions. Conversely, for 63 (52.9%) conditions, neither XR nor US had any diagnostic utility. For management, XR was highly useful for 24 conditions, while US was highly useful for 21.</p><p><strong>Discussion: </strong>In over one-third of conditions, XR possesses unique capabilities either complementary or superior to US. XR possesses superior diagnostic utility for bony injuries, dental conditions, and some pulmonary conditions, and superior management capability for orthopedic reductions and device placement confirmation. This analysis suggests future missions may consider augmenting the medical system with portable radiography if resource constraints allow, and future work should quantify the risk reduction provided by this capability. Boyle MJ, Pohlen M, Lehnhardt K, Parmar P, Easter B. X-ray and ultrasound for human spaceflight using the NASA IMPACT conditions list. Aerosp Med Hum Perform. 2026; 97(3):176-184.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"176-184"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurophysiological Measures to Detect Spatial Disorientation.","authors":"Kathryn A Feltman, Jordayne Wilkins, Isaiah Persson, Spencer Stonehouse","doi":"10.3357/AMHP.6736.2026","DOIUrl":"10.3357/AMHP.6736.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Maintaining spatial orientation in flight remains a critical aspect of aviation safety. Monitoring an aviator's neurophysiological patterns may provide insight and opportunity to mitigate loss of spatial orientation. However, few studies have examined the utility of such measures. The purpose of the current study was to conduct a scoping review to document the research activities that have examined neurophysiological measures in relation to spatial orientation.</p><p><strong>Methods: </strong>Four databases were searched for literature using neurophysiological measures in studies assessing disorientation. The initial search yielded 110,135 articles. After removing duplicates and articles not meeting criteria, nine articles were reviewed.</p><p><strong>Results: </strong>One of the nine articles used an aviation-relevant task. From the nine articles, evidence suggested roles of the parietal and frontal lobes maintaining orientation. Regarding the aviation-relevant task, the frontal lobe was supported for its involvement in the experience of unidentified spatial disorientation. Across all, the frontal lobe was consistently implicated (support from six studies) for its role in orientation. However, the studies differed in neurophysiological measures and outcomes evaluated. Electroencephalography emerged as a potential candidate for detecting disorientation, with six studies using it as the neurophysiological measurement device.</p><p><strong>Discussion: </strong>Although the literature is limited on aviation-relevant tasks, there is strong support for activation patterns in the parietal and frontal lobes for orientation. This provides a starting point for experimental studies to further capture what patterns can be detected from neurophysiology when disorientation is experienced. Further research on aviation applications and using consistent measures is needed to further develop this area of research. Feltman KA, Wilkins J, Persson I, Stonehouse S. Neurophysiological measures to detect spatial disorientation. Aerosp Med Hum Perform. 2026; 97(3):194-203.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"194-203"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glycated Hemoglobin vs. Fasting Glucose in Routine Screening of Military Aircrew.","authors":"Michal A Kurek, Filip Kwiatkowski, Dariusz Popiela, Marcin Biernacki, Agata Gaździńska, Magdalena Rola","doi":"10.3357/AMHP.6755.2026","DOIUrl":"10.3357/AMHP.6755.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes screening is crucial in aviation medicine because of its impact on flight safety. This study compared the diagnostic performance of fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) in Polish Air Force pilots ages 45 yr and older and assessed their role in optimizing screening protocols. Additionally, the study examined the relationships between age, body mass index (BMI), body fat percentage, and prediabetes or diabetes prevalence in this population.</p><p><strong>Methods: </strong>This study included 175 military flight personnel who were undergoing periodic medical examinations. Individuals with diagnosed diabetes were excluded. FPG, HbA1c, age, BMI and body fat percentage were measured. A multivariate regression model was used to examine their associations.</p><p><strong>Results: </strong>Among 175 male pilots ages 45-60 yr (M = 50.05, SD = 3.74), 68.6% had normal HbA1c, 30.3% were prediabetic, and 1.1% were diabetic. FPG classified 43.4% of the subjects as normal, 53.1% as prediabetic, and 3.4% as diabetic. A normal BMI was found in 23.4% of the subjects, whereas a normal body fat percentage occurred in 37%. Regression revealed that body fat percentage was more strongly associated with HbA1c than was age or BMI.</p><p><strong>Discussion: </strong>HbA1c testing has proven to be a practical and cost-effective tool for detecting abnormal glucose metabolism in military aircrew, particularly when used alongside FPG. Its implementation has reduced the need for further testing and may streamline periodic evaluations. Additionally, body fat percentage emerged as a more reliable predictor of dysglycemia than BMI was, suggesting the value of including body composition assessments in routine screenings. Kurek MA, Kwiatkowski F, Popiela D, Biernacki M, Gaździńska A, Rola M. Glycated hemoglobin vs. fasting glucose in routine screening of military aircrew. Aerosp Med Hum Perform. 2026; 97(3):169-175.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"169-175"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Artery Disease Detection and Disposition in Aircrew.","authors":"Gary Gray, David Holdsworth, Norbert Guettler, Lysette Broekhuizen, Thomas Syburra, Joanna d'Arcy, Denis Bron, Olivier Manen, Eddie Davenport","doi":"10.3357/AMHP.6677.2026","DOIUrl":"10.3357/AMHP.6677.2026","url":null,"abstract":"<p><strong>Introduction: </strong>Acute coronary events continue to represent a threat to aviation safety and mission completion and comprise a significant cause of loss of medical certification in both military and civilian aircrew. In the age range of active aircrew, coronary events often present as a plaque rupture event with acute incapacitation as the initial manifestation. The identification of asymptomatic aircrew with a high risk for an acute coronary event remains a major challenge to aviation medical practitioners. For aircrew who have had a coronary event or are have significant atherosclerosis, the challenge is to guide the appropriate evaluations to allow a risk assessment for consideration for continuing flight duties.</p><p><strong>Case series: </strong>Using a series of four case studies, this article will explore the evaluation, treatment, and proper aeromedical disposition of coronary artery disease (CAD). Cases will include CAD screening, asymptomatic non-obstructive CAD, asymptomatic obstructive/ischemic CAD, and symptomatic CAD with myocardial infarction.</p><p><strong>Discussion: </strong>This paper presents the current benchmark for assessing aircrew for occult coronary disease and for assessment and disposition of aircrew with known coronary disease with data derived from current aeromedical and clinical literature, as well as the expert consensus of the North Atlantic Treaty Organization Working Group on Occupational Cardiology (HFM WG 251, 316). Gray G, Holdsworth D, Guettler N, Broekhuizen L, Syburra T, D'Arcy J, Bron D, Manen O, Davenport E. Coronary artery disease detection and disposition in aircrew. Aerosp Med Hum Perform. 2026; 97(3):210-217.</p>","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"97 3","pages":"210-217"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146206462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}