Aerospace medicine and human performance最新文献_第3页

Modafinil Subjectively Does Not Impair Sleep in Aviators After a Period of Extended Wakefulness. 莫达非尼主观上不会影响长时间清醒后飞行员的睡眠。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-06-01 DOI: 10.3357/AMHP.6390.2024

Yara Q Wingelaar-Jagt, Thijs T Wingelaar, Willem J Riedel, Johannes G Ramaekers

{"title":"Modafinil Subjectively Does Not Impair Sleep in Aviators After a Period of Extended Wakefulness.","authors":"Yara Q Wingelaar-Jagt, Thijs T Wingelaar, Willem J Riedel, Johannes G Ramaekers","doi":"10.3357/AMHP.6390.2024","DOIUrl":"10.3357/AMHP.6390.2024","url":null,"abstract":"INTRODUCTION: Modafinil is used as a countermeasure to limit the effects of fatigue in military aviation. However, literature is conflicting about its negative effects on subsequent sleep.METHODS: This randomized placebo-controlled trial conducted by the Center of Man in Aviation of the Royal Netherlands Airforce is part of a larger study. It included 32 subjects (mean age 35 yr old, 84% male) who followed a normal daily routine and stayed awake the subsequent night. At midnight, all subjects received either 300 mg caffeine, 200 mg modafinil, or placebo. At the end of the test night, subjects were awake for a median period of 26 h. Afterwards, sleep questionnaires containing qualitative (Groningen Sleep Quality Scale) and quantitative parameters of sleep for the subsequent day (recovery sleep) and consecutive night (post-test sleep) were completed and statistically analyzed using Friedman and Wilcoxon signed rank tests.RESULTS: A statistically significant difference in the reported recovery sleep was observed. The modafinil group slept 30% shorter than placebo, but sleep efficiency was not statistically different. Quantitatively post-test sleep did not vary statistically significantly between the three groups. However, Groningen Sleep Quality Scale scores were lower post-test than pre-test in the modafinil group, while this was not the case in the caffeine and placebo group.DISCUSSION:This study found that modafinil subjectively does not negatively impact recovery sleep or subsequent nighttime sleep after an extended period of wakefulness and suggests it may decrease the need for recovery sleep compared to placebo or caffeine.Wingelaar-Jagt YQ, Wingelaar TT, Riedel WJ, Ramaekers JG. Modafinil subjectively does not impair sleep in aviators after a period of extended wakefulness. Aerosp Med Hum Perform. 2024; 95(6):290-296.","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"95 6","pages":"290-296"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141092293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orbital Solitary Fibrous Tumor in a Commercial Airline Pilot. 一名商业航空公司飞行员的眼眶孤立性纤维瘤。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-06-01 DOI: 10.3357/AMHP.6385.2024

Munise Altinbas, Ayse Ozpınar, Müslime Akbaba, Senay A Nacaroglu, Mohammad Sargolzaeimoghaddam, Maral Sargolzaeimoghaddam

{"title":"Orbital Solitary Fibrous Tumor in a Commercial Airline Pilot.","authors":"Munise Altinbas, Ayse Ozpınar, Müslime Akbaba, Senay A Nacaroglu, Mohammad Sargolzaeimoghaddam, Maral Sargolzaeimoghaddam","doi":"10.3357/AMHP.6385.2024","DOIUrl":"10.3357/AMHP.6385.2024","url":null,"abstract":"BACKGROUND: In the literature, central serous retinopathy (CSR) accompanying solitary fibrous tumors (SFT) in a pilot has not been reported. In airline pilots, mass effect-related symptoms such as diplopia, ptosis, etc., seen with orbital tumors may endanger flight safety.CASE REPORT: A 62-yr-old male commercial airline pilot presented with blurred vision in the right eye. He had been receiving treatment for 2 mo because of CSR. His visual acuity was 10/20 in the right eye and 20/20 in the left. During examination, ptosis and exophthalmos were noticed in the right eye. Ocular movements were free in all cardinal directions and there was downward displacement in the right eye. There was no diplopia. Magnetic resonance imaging revealed a 1.5- to 2-cm well-defined contrast-enhancing mass in the lateral extraconal orbit. His medical flight certificate was suspended for 3 mo due to decreased visual acuity and superior visual defect. Superior orbitotomy was performed without any complication. Ptosis and CSR had regressed 1 wk after surgery. All systemic and ophthalmological examinations met aviation medical certificate requirements. He returned to flight on the condition of being checked every 3 mo. At the 1-yr follow-up, there was no sign of recurrences of SFT or CSR.DISCUSSION: SFTs are slow-growing neoplasms that can manifest symptoms related to mass effect. In the current literature, there are no reported cases of the coexistence of orbital SFT and CSR or pilots able to resume flight duties only 1 wk after a successful orbitotomy and tumor resection surgery.Altinbas M, Ozpınar A, Akbaba M, Nacaroglu SA, Sargolzaeimoghaddam M, Sargolzaeimoghaddam M. Orbital solitary fibrous tumor in a commercial airline pilot. Aerosp Med Hum Perform. 2024; 95(6):333-336.","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"95 6","pages":"333-336"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141092295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional Dyspepsia and Tricyclic Antidepressant Use in a Naval Flight Officer. 一名海军飞行军官的功能性消化不良和三环类抗抑郁药的使用。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-06-01 DOI: 10.3357/AMHP.6404.2024

Robert Crutcher, Nathan Kolasinski

{"title":"Functional Dyspepsia and Tricyclic Antidepressant Use in a Naval Flight Officer.","authors":"Robert Crutcher, Nathan Kolasinski","doi":"10.3357/AMHP.6404.2024","DOIUrl":"10.3357/AMHP.6404.2024","url":null,"abstract":"BACKGROUND: Functional dyspepsia is a disorder of gut-brain interaction that has the potential to impact aviation performance. Proton pump inhibitors are well-tolerated but are only effective in one half of cases. Second-line treatments, including tricyclic antidepressants, are associated with drowsiness and are not routinely approved for use in aviators. We present a case of a Naval Flight Officer with functional dyspepsia who was successfully treated with amitriptyline and returned to flying status.CASE REPORT: A 23-yr-old male Naval Flight Officer presented with postprandial fullness and epigastric pain. His symptoms were refractory to trials of acid suppression and lifestyle modification. An extensive evaluation by Gastroenterology, including upper endoscopy, did not reveal an organic cause of his symptoms and he was diagnosed with functional dyspepsia. The patient's symptoms resolved with a trial of amitriptyline. Neuropsychological testing demonstrated no medication effect on cognitive performance. A waiver to resume flying duties on amitriptyline was submitted to the Naval Aerospace Medical Institute and was approved.DISCUSSION: We present the second known waiver issued in U.S. Naval aviation history for the use of amitriptyline to treat a gastrointestinal disorder. Amitriptyline is not commonly waived due to the potential for unacceptable cognitive side-effects in the flight environment. However, neuropsychological testing to assess for a possible medication effect on performance can be used to inform an aeromedical disposition and, in this case, allowed for a return to flight status.Crutcher R, Kolasinski N. Functional dyspepsia and tricyclic antidepressant use in a naval flight officer. Aerosp Med Hum Perform. 2024; 95(6):337-340.","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"95 6","pages":"337-340"},"PeriodicalIF":0.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141092287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wing meeting registration. Wing 会议注册。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01

引用次数: 0

An Honor to Serve. 服务的荣耀

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01 DOI: 10.3357/AMHP.955PP.2024

Joseph Dervay

引用次数: 0

Modern Magnetic Resonance Imaging Modalities to Advance Neuroimaging in Astronauts. 推进宇航员神经成像的现代磁共振成像模式。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01 DOI: 10.3357/AMHP.6395.2024

Lila Berger, Ford Burles, Tejdeep Jaswal, Rebecca Williams, Giuseppe Iaria

{"title":"Modern Magnetic Resonance Imaging Modalities to Advance Neuroimaging in Astronauts.","authors":"Lila Berger, Ford Burles, Tejdeep Jaswal, Rebecca Williams, Giuseppe Iaria","doi":"10.3357/AMHP.6395.2024","DOIUrl":"https://doi.org/10.3357/AMHP.6395.2024","url":null,"abstract":"INTRODUCTION: The rapid development of the space industry requires a deeper understanding of spaceflight's impact on the brain. MRI research reports brain volume changes following spaceflight in astronauts, potentially affecting cognition. Recently, we have demonstrated that this evidence of volumetric changes, as measured by typical T1-weighted sequences (e.g., magnetization-prepared rapid gradient echo sequence; MPRAGE), is error-prone due to the microgravity-related redistribution of cerebrospinal fluid in the brain. More modern neuroimaging methods, particularly dual-echo MPRAGE (DEMPRAGE) and magnetization-prepared rapid gradient echo sequence utilizing two inversion pulses (MP2RAGE), have been suggested to be resilient to this error. Here, we tested if these imaging modalities offered consistent segmentation performance improvements in some commonly employed neuroimaging software packages.METHODS: We conducted manual gray matter tissue segmentation in traditional T1w MRI images to utilize for comparison. Automated tissue segmentation was performed for traditional T1w imaging, as well as on DEMPRAGE and MP2RAGE images from the same subjects. Statistical analysis involved a comparison of total gray matter volumes for each modality, and the extent of tissue segmentation agreement was assessed using a test of similarity (Dice coefficient).RESULTS: Neither DEMPRAGE nor MP2RAGE exhibited consistent segmentation performance across all toolboxes tested.DISCUSSION: This research indicates that customized data collection and processing methods are necessary for reliable and valid structural MRI segmentation in astronauts, as current methods provide erroneous classification and hence inaccurate claims of neuroplastic brain changes in the astronaut population.Berger L, Burles F, Jaswal T, Williams R, Iaria G. Modern magnetic resonance imaging modalities to advance neuroimaging in astronauts. Aerosp Med Hum Perform. 2024; 95(5):245-253.","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"95 5","pages":"245-253"},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cover-to-Cover. 封面到封面

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01

引用次数: 0

Photorefractive Keratectomy and Laser-Assisted In Situ Keratomileusis on 6-Month Space Missions. 为期 6 个月的太空任务中的光屈光性角膜切除术和激光辅助原位角膜磨镶术。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01 DOI: 10.3357/AMHP.6368.2024

C Robert Gibson, Thomas H Mader, William Lipsky, Steven C Schallhorn, William J Tarver, Rahul Suresh, Tyler N Hague, Tyson J Brunstetter

{"title":"Photorefractive Keratectomy and Laser-Assisted In Situ Keratomileusis on 6-Month Space Missions.","authors":"C Robert Gibson, Thomas H Mader, William Lipsky, Steven C Schallhorn, William J Tarver, Rahul Suresh, Tyler N Hague, Tyson J Brunstetter","doi":"10.3357/AMHP.6368.2024","DOIUrl":"10.3357/AMHP.6368.2024","url":null,"abstract":"BACKGROUND: This article documents the stability of photorefractive keratectomy (PRK) and laser-assisted in situ keratomileusis (LASIK) in two astronauts during 6-mo missions to the International Space Station.CASE REPORTS: Ocular examinations including visual acuity, cycloplegic refraction, slit lamp examination, corneal topography, central corneal thickness, optical biometry (axial length/keratometry), applanation tonometry, and dilated fundus examination were performed on each astronaut before and after their missions, and in-flight visual acuity testing was done on flight day 30, 90, and R-30 (30 d before return). They were also questioned regarding visual changes during flight.DISCUSSION: We documented stable vision in both PRK and LASIK astronauts during liftoff, entry into microgravity, 6 mo on the International Space Station, descent, and landing. Our results suggest that both PRK and LASIK are stable and well tolerated during long-duration spaceflight.Gibson CR, Mader TH, Lipsky W, Schallhorn SC, Tarver WJ, Suresh R, Hauge TN, Brunstetter TJ. Photorefractive keratectomy and laser-assisted in situ keratomileusis on 6-month space missions. Aerosp Med Hum Perform. 2024; 95(5):278-281.","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"95 5","pages":"278-281"},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival After Ditching in Motorized Aircraft, 1989-2022. 1989-2022 年机动飞机甩尾后的存活率。

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01 DOI: 10.3357/AMHP.6332.2024

Volker C Schick, Douglas D Boyd, Catherina Hippler, Jochen Hinkelbein

{"title":"Survival After Ditching in Motorized Aircraft, 1989-2022.","authors":"Volker C Schick, Douglas D Boyd, Catherina Hippler, Jochen Hinkelbein","doi":"10.3357/AMHP.6332.2024","DOIUrl":"https://doi.org/10.3357/AMHP.6332.2024","url":null,"abstract":"INTRODUCTION: Although an unintended aircraft landing on water (referred to as ditching) is a rare event, the potential for occupant injury/fatality increases immediately following the event due to adverse conditions. However, to date, few studies have addressed the subject. Herein, ditching events and post-ditching survival were investigated.METHODS: Ditchings (1982-2022) in the United States were identified from the National Transportation Safety Board database. Occupant injury severity, aircraft type, pilot experience, flight conditions, and number of occupants were extracted. Poisson distribution, the Chi-squared test (2-tailed), Mann-Whitney U test, and Kruskal-Wallis one-way analysis of variance were employed.RESULTS: A total of 96 ditchings were identified. A systematic survey was hampered by the lack of a standardized reporting matrix in the reports. In total, 77 reports were included in the analysis. Across all ditchings, 128 of 169 (76%) occupants survived ditching and were rescued. Importantly, the initial ditching event was survived by 95% of all occupants. However, 32 (19%) occupants died post-ditching by drowning (21/32 cases) or for undetermined reasons. Considering probability per ditching event, in 26 (34%) of all ditchings, one or more occupants was/were fatally injured.DISCUSSION: Initial survival of the emergency ditching is high. Drowning was the leading cause of death after ditching and reduced the overall survival to 76%. Further investigation is needed to identify risk factors for fatal outcomes and/or improve probability of survival after ditching.Schick VC, Boyd DD, Hippler C, Hinkelbein J. Survival after ditching in motorized aircraft, 1989-2022. Aerosp Med Hum Perform. 2024; 95(5):254-258.","PeriodicalId":7463,"journal":{"name":"Aerospace medicine and human performance","volume":"95 5","pages":"254-258"},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140875480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

This Month in Aerospace Medicine History: May. 航空航天医学史上的这个月：五月

IF 0.9 4区医学

Aerospace medicine and human performance Pub Date : 2024-05-01 DOI: 10.3357/AMHP.6458.2024

引用次数: 0