Alex Demarsh, Pedro Nascimento de Lima, Cassidy Nelson, Javier Rojas Aguilera, Nathan Duarte, Sella Nevo, Henry H Willis
{"title":"Strategies to Improve Detection of Novel Pandemic Pathogens: Cost Versus Detection Performance for Promising Pathogen-Agnostic Detection Workflows.","authors":"Alex Demarsh, Pedro Nascimento de Lima, Cassidy Nelson, Javier Rojas Aguilera, Nathan Duarte, Sella Nevo, Henry H Willis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This RAND analysis compares three pathogen-agnostic biosurveillance strategies-syndromic, wearable, and environmental-using modeling to assess cost versus detection performance. Environmental sampling detected outbreaks fastest, followed by wearable sensors, although both lost advantage with highly transmissible or symptomatic diseases. Limited pilot deployments could refine real-world costs and validate early-warning performance.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Rollison, Skye A Miner, Elaine Li, Michael W Robbins, Daniel Shinnick, Danielle Schlang
{"title":"Exploring Contraceptive Care and Access Experiences of Veterans.","authors":"Julia Rollison, Skye A Miner, Elaine Li, Michael W Robbins, Daniel Shinnick, Danielle Schlang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Practical access to contraceptive care and the ability to choose care that meets one's needs and preferences are important for an individual's health and well-being in the United States. Although a significant amount of research has been done to examine access to contraceptive care, particularly among civilian women, there is significantly less understanding about the needs, preferences, and experiences of veterans. The body of evidence on veterans' contraceptive use and knowledge of and experiences with contraceptive care shows significant gaps. Additionally, veterans' ability to use their preferred methods of contraception is uneven and influenced by the quality of counseling they receive, the availability of trained providers, and systemic disparities in access. To address these gaps, the authors of this study conducted a nationally representative survey of men and women veterans' access to, knowledge of, and use of contraception and contraceptive care within and outside the Veterans Health Administration (VHA) and its network of community care providers. This survey was supplemented by in-depth interviews. The authors aimed to better understand gaps in contraceptive access and choice for U.S. veterans of reproductive age and how these gaps might vary by certain characteristics, such as sex or where veterans receive or access care. The authors also present recommendations for care providers and veteran-serving organizations to address gaps in contraceptive knowledge, access, and care for veteran men and women.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"8"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Bouey, Carrie Dolan, Agnes Xiangzhen Wang, Rakesh Pandey
{"title":"China's Global Health Activities in Africa: Historical Perspectives and Case Studies.","authors":"Jennifer Bouey, Carrie Dolan, Agnes Xiangzhen Wang, Rakesh Pandey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this study, the authors describe the evolution of the People's Republic of China's global health activities and related policies in Africa from the 1960s through the present and provide field case studies of two African nations-Sierra Leone and Kenya-that have received health aid from China. They then analyze China's use of global health support in Africa as a tool of soft power. The need to understand China's global health activities has intensified, given that Western, particularly U.S., foreign health aid policies are changing, prompting questions about whether China will shift its policies to strengthen its soft power in Africa and away from the decade-old Belt and Road Initiative's overarching Sino-centric trade focus. This analysis of China's health aid history, its current role in African health aid, and its recent reform called for by President Xi Jinping's Global Development Initiative is intended to help U.S. policymakers understand China's decisionmaking and implementation strategy for foreign aid. The analysis of the advantages and weaknesses of China's approaches can offer lessons to both donor countries and African countries that receive global health aid from China. The authors offer policy recommendations for the United States and for African countries.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Graham DiGuiseppi, Dana Schultz, Rebecca L Collins, Elizabeth Roth, Nicole K Eberhart
{"title":"Evaluation of \"Live Beyond\": A Public Awareness Campaign to Address Adverse Childhood Experiences and Toxic Stress in California.","authors":"Graham DiGuiseppi, Dana Schultz, Rebecca L Collins, Elizabeth Roth, Nicole K Eberhart","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Adverse childhood experiences (ACEs) are potentially traumatic events, such as abuse, neglect, and household stress, that occur before the age of 18. ACEs are common: Almost two-thirds of U.S. adults report at least one ACE, and nearly one-fifth report four or more. ACEs can have wide-ranging effects on mental and physical health and social relationships. These negative health outcomes come about through a process known as toxic stress, a condition characterized by heightened and prolonged physiological and psychological changes that can persist into adulthood. Given the substantial cost of ACEs to society and their potential to affect future generations, broad population-level interventions are needed. For this study, the authors evaluated Live Beyond, a public awareness campaign funded by the Office of the California Surgeon General and carried out by Civilian, a social marketing and communications agency. Civilian used social marketing to reach two priority populations: youth and young adults ages 16 to 25, and caregivers of youth ages 8 to 16 in California. The study presents findings of a process evaluation that used document review to detail the planning, development, and implementation of the campaign, and an outcome evaluation that used surveys precampaign and ten months postimplementation to examine the campaign's impact on transition-age youth's and caregivers' ACE-related knowledge and awareness, attitudes and beliefs, skills and actions, and well-being. The authors concluded that, if continued for a longer time, Live Beyond could make headway in addressing the high prevalence and cost of ACEs and toxic stress in California.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978669/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessie Wang, R Gordon Rinderknecht, Daniel Hicks, Hankyung Kate Jun, Temusa Rukundo-Ayeh
{"title":"Time as Resource and Experience: An Interdisciplinary Framework for Understanding the True Cost of Caregiving.","authors":"Jessie Wang, R Gordon Rinderknecht, Daniel Hicks, Hankyung Kate Jun, Temusa Rukundo-Ayeh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors of this study develop an interdisciplinary time use framework for measuring caregiving costs. Using survey data, they show that caregivers' well-being depends less on total hours and more on experiences, such as time fragmentation, unpredictability, and reduced time quality. Findings highlight heterogeneous caregiver needs and support data-driven, targeted policy interventions.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"6"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mallika Bhandarkar, Stephanie Brooks Holliday, Kami Ehrich, Alexandra Bilder, Elizabeth Marsolais
{"title":"Evaluation of the Peaceful Connections Violence Prevention Program: Local Evaluation Report.","authors":"Mallika Bhandarkar, Stephanie Brooks Holliday, Kami Ehrich, Alexandra Bilder, Elizabeth Marsolais","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Peaceful Connections program, implemented by the Boys & Girls Clubs (BGC) of Santa Monica and eight partner Clubs, was launched using a California grant to address youth violence in seven cities disproportionately affected by violence in Los Angeles County. The targeted communities also experience systemic barriers related to poverty, academic underachievement, and justice system involvement. The overarching purpose of Peaceful Connections was to leverage Club-based, evidence-informed interventions, including group and individualized services, to reduce risk factors for youth violence, strengthen protective factors, and improve educational and career-readiness outcomes for youth who are most at risk. The program built on existing group-based programming available through BGC, which focuses on social-emotional, leadership, and career skills, and added a case management component for higher-risk youth. In this study, the authors share their findings from a process and outcome evaluation of the Peaceful Connections program, and they include recommendations for how BGC could improve both the program and evaluation efforts going forward.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Hoch, Jose Martinez, Rushil Bakhshi, Maggie Hieber, Aaron Presser, Thomas Tartaglia
{"title":"A Review of U.S. Military Traumatic Brain Injury Studies: Trends, Gaps, and Opportunities.","authors":"Emily Hoch, Jose Martinez, Rushil Bakhshi, Maggie Hieber, Aaron Presser, Thomas Tartaglia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this scoping review of military service-related traumatic brain injury (TBI) studies, authors map the progress of TBI research from January 2015 through June 2025 and identify overlaps and gaps in specific areas. They also highlight areas that received the most-focused investment. Service-related TBI is a signature wound of war, affecting more than 500,000 service members since 2000, and special operations forces (SOF) are at particularly high risk because of frequent blast exposures and repetitive neurological stresses. Many TBIs go undiagnosed or are mild, yet they often co-occur with such conditions as posttraumatic stress disorder and depression and lead to significant long-term health impacts. Despite substantial federal and private investment, TBI research remains fragmented and siloed, highlighting the need for a comprehensive assessment of research efforts and funding in this critical area. By highlighting both research achievements and persistent gaps, this study provides a road map for policymakers, funders, and researchers to align priorities to close knowledge gaps. A more coordinated research agenda is essential to advance prevention, diagnosis, treatment, and long-term recovery and ensure comprehensive care and support for all service members and veterans living with TBI.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing Development of LRRK2-Targeted Therapeutics for Parkinson's Disease: Conference Proceedings and Roadmap for Research.","authors":"Zachary Predmore, Shannon D Donofry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In June 2025, the Michael J. Fox Foundation for Parkinson's Research (MJFF) hosted an in-person workshop, LRRK2-Targeted Therapeutics Roundtable: Advancing Clinical Development for Parkinson's Disease, convening researchers, clinicians, industry representatives, and funders to discuss opportunities for communication, coordination, and collaboration to advance the development of therapeutics that target leucine-rich repeat kinase 2 (LRRK2). The purpose of this multistakeholder workshop was to create a collaborative platform for researchers, clinicians, industry representatives, and funders to discuss the trade-offs and opportunities in using various clinical trial strategies, including trade-offs and opportunities related to target populations, endpoints, treatment durations, and target labels. By fostering precompetitive dialogue on clinical development for LRRK2-targeted therapies, MJFF sought to ensure that sponsors design robust and informative clinical trials that can accelerate drug development and meaningfully advance efforts to deliver effective treatments to patients. In this study, the authors highlight the topics discussed in the workshop and outline the roundtable participants' immediate- and medium-term goals for advancing LRRK2-targeted research and therapeutic development. Key immediate actions mentioned during the roundtable include developing a comprehensive inventory of existing LRRK2 cohorts and their associated clinical and biologic data and biospecimens to find opportunities for data acquisition and harmonization. The authors also discuss what participants cited as the need to develop and validate LRRK2 pathway biomarkers to facilitate population identification and assessment of therapeutic efficacy, and to use these biomarkers to identify \"LRRK2-like\" individuals with idiopathic Parkinson's disease who exhibit LRRK2 pathway dysfunction.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter from the Editor.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"letter"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Rollison, Zara Fatima Abdurahaman, Lisa H Jaycox, Viviana Mercado
{"title":"Developing a Research Agenda to Improve Rural Health Access and Quality in West Virginia.","authors":"Julia Rollison, Zara Fatima Abdurahaman, Lisa H Jaycox, Viviana Mercado","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study presents West Virginia's rural health challenges-workforce shortages, chronic disease, infrastructure gaps, and access barriers-and describes a preliminary research agenda to guide improvements. The authors identify practical research priorities, highlight promising programs, and emphasize culturally responsive, community-engaged approaches to improve health outcomes in rural health services throughout the state.</p>","PeriodicalId":74637,"journal":{"name":"Rand health quarterly","volume":"13 2","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12978671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}