{"title":"[Ghosts and half-shadows-Shedding light on the mysterious world of inflammations and infections of the bone].","authors":"Maximilian Reiser, Annie Horng","doi":"10.1007/s00117-025-01490-6","DOIUrl":"https://doi.org/10.1007/s00117-025-01490-6","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":"65 9","pages":"639-641"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hematogenous osteomyelitis in children : A feared pediatric emergency].","authors":"Markus Uhl, Markus Hufnagel","doi":"10.1007/s00117-025-01469-3","DOIUrl":"10.1007/s00117-025-01469-3","url":null,"abstract":"<p><strong>Clinical/methodological issue: </strong>Hematogenously disseminated osteomyelitis in children and adolescents is an acute disease with a substantial threat to the health of a child or adolescent. Due to the destruction of bones or joints within hours to days and the risk of bacterial sepsis, it is a feared pediatric emergency that requires hospitalization in a children's hospital and rapid action.</p><p><strong>Standard radiological methods: </strong>The standard radiological procedures are X‑ray, sonography and magnetic resonance imaging (MRI).</p><p><strong>Methodological innovations/performance: </strong>Contrast-enhanced MRI has established itself as the gold standard for the detection of osteomyelitis.</p><p><strong>Achievements: </strong>It is characterized by a very high sensitivity and high specificity.</p><p><strong>Practical recommendations: </strong>If there is a clinical suspicion of bacterial osteomyelitis, an MRI diagnosis must be carried out quickly.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"650-655"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Spondylitis and spondylodiscitis].","authors":"Torsten Diekhoff, Dominik Deppe","doi":"10.1007/s00117-025-01478-2","DOIUrl":"10.1007/s00117-025-01478-2","url":null,"abstract":"<p><strong>Background: </strong>Inflammatory spinal disorders include infectious spondylodiscitis and noninfectious spondyloarthritis. Their clinical differentiation and distinction from degenerative conditions are crucial.</p><p><strong>Objective: </strong>This review aims to clearly describe infectious and noninfectious spondylitis, highlighting diagnostic and therapeutic challenges.</p><p><strong>Materials and methods: </strong>Analysis of current literature and clinical experience regarding infection pathways, clinical symptoms, and characteristic findings in imaging modalities (magnetic resonance imaging [MRI], computed tomography [CT], X‑ray).</p><p><strong>Results: </strong>Infectious spondylodiscitis typically arises through hematogenous or iatrogenic routes, predominantly affecting older patients and presenting specific changes detectable by MRI and CT. Noninfectious spondylarthritis, such as axial spondyloarthritis, typically manifests as enthesitis with characteristic structural lesions. MRI is highly sensitive in identifying active inflammatory lesions, while CT and X-ray are advantageous for visualizing chronic structural changes.</p><p><strong>Conclusion: </strong>Diagnosing inflammatory spinal disorders remains challenging and requires a combination of clinical and imaging findings. Unified definitions and standardized diagnostic procedures are essential to minimize incorrect assessment and facilitate targeted therapy.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"688-699"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Diagnosis and treatment of acute pulmonary embolism].","authors":"M Hecker, M Bayer, G A Krombach, N Sommer","doi":"10.1007/s00117-025-01505-2","DOIUrl":"10.1007/s00117-025-01505-2","url":null,"abstract":"<p><p>Acute pulmonary embolism is a common and potentially fatal condition in intensive care and emergency medicine. The mortality rate within the first few hours of its occurrence is particularly high; thus, even in the event of clinical suspicion, immediate initiation of diagnostics and treatment is crucial. The current European and national guidelines on acute pulmonary embolism provide valuable and practical support on this topic and form the basis of this review. A particular focus lies in the presentation of a risk-adapted and algorithm-based diagnostic and therapeutic approach. In particular, there are new recommendations regarding risk stratification and differentiated therapy, which are discussed in this article.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"705-718"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Nonbacterial osteitis: innovations in imaging : Advances in radiology and clinical management].","authors":"Haroun Bel Hadj Jrad, Markus Hufnagel","doi":"10.1007/s00117-025-01479-1","DOIUrl":"10.1007/s00117-025-01479-1","url":null,"abstract":"<p><strong>Background: </strong>Nonbacterial osteitis (NBO) is a rare autoinflammatory bone disease primarily affecting children and adolescents. The absence of a unified definition and standardized diagnostic criteria complicates clinical diagnosis and management.</p><p><strong>Objectives: </strong>This study aims to systematically review the current literature regarding the definition of NBO and assess the role of imaging particularly whole-body magnetic resonance imaging (MRI) as well as the use of the radiologic index for nonbacterial osteitis (RINBO) score in diagnosis and disease monitoring.</p><p><strong>Materials and methods: </strong>A thorough literature review was conducted, focusing on radiological methods including whole-body magnetic resonance imaging (WB MRI) and the application of the RINBO score.</p><p><strong>Results: </strong>Whole-body MRI demonstrates high sensitivity for detecting inflammatory bone lesions and proves useful for both diagnosis and follow-up. Conventional X‑ray imaging offers additional information about structural bone damage. The RINBO score serves as a practical tool for standardizing diagnostic interpretation.</p><p><strong>Conclusion: </strong>The combination of whole-bodyMRI and the RINBO score enables structured and reproducible evaluation of NBO. Establishing uniform diagnostic criteria remains a central goal for future research.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"674-680"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Osteomyelitis, septic arthritis, nonbacterial osteomyelitis, SAPHO syndrome in children : What clinicians want to know from the radiologist?]","authors":"Johannes-Peter Haas","doi":"10.1007/s00117-025-01470-w","DOIUrl":"10.1007/s00117-025-01470-w","url":null,"abstract":"<p><strong>Clinical issue: </strong>Monofocal and multifocal bone lesions in children and adolescents may result from various diseases. Apart from inflammatory entities malignancy is the most important issue to be ruled out.</p><p><strong>Standard treatment: </strong>Various diseases. Apart from inflammatory origin malignancy is the most important issue to be ruled out. Imaging in particular magnetic resonance imaging (MRI) has an important role for the diagnostic process.</p><p><strong>Diagnostic work-up: </strong>Osteomyelitis and septic arthritis on the one hand and nonbacterial osteomyelitis and synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome (SAPHO) syndrome on the other may present with unspecific clinical symptoms and overlapping disease courses.</p><p><strong>Achievements: </strong>Radiology is important not only for diagnostics but for treatment planning.</p><p><strong>Practical recommendations: </strong>This review focusses on questions to the radiologist from the clinician's view.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"642-649"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcel Opitz, Luca Salhöfer, Johannes Haubold, Isabel Molwitz, Marco Das
{"title":"[Influence of artificial intelligence on decisions in radiology using the example of lung cancer screening].","authors":"Marcel Opitz, Luca Salhöfer, Johannes Haubold, Isabel Molwitz, Marco Das","doi":"10.1007/s00117-025-01496-0","DOIUrl":"10.1007/s00117-025-01496-0","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"700-704"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12390861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Osteomyelitis in adults].","authors":"L Camp, M-A Weber","doi":"10.1007/s00117-025-01482-6","DOIUrl":"10.1007/s00117-025-01482-6","url":null,"abstract":"<p><strong>Background: </strong>Osteomyelitis (OM) refers to inflammatory diseases of the bone caused by microorganisms. A continuous increase in the prevalence of osteomyelitis has been observed. Despite advances in medical care, early diagnosis remains challenging due to initially nonspecific symptoms, particularly in elderly or immunocompromised patients.</p><p><strong>Objective: </strong>This article aims to provide a structured overview of the pathogenesis of OM, the role of imaging, and the most important differential diagnoses.</p><p><strong>Methods: </strong>Narrative, literature-based review incorporating current guidelines, radiological protocols, and imaging characteristics.</p><p><strong>Results: </strong>Magnetic resonance imaging (MRI) is the diagnostic gold standard. It enables early detection of bone marrow edema and inflammatory changes. The \"penumbra sign\" and the \"ghost sign\" contribute in distinguishing tumors and Charcot arthropathy, respectively. Computed tomography (CT) is essential for chronic OM and sequestrum detection. Flourodeoxyglucose-18 positron emission tomography (FDG-PET) can be helpful in unclear cases, particularly in patients with prosthetic implants.</p><p><strong>Conclusion: </strong>A multidisciplinary, imaging-guided approach is critical for early diagnosis, treatment planning, and follow-up in OM. Radiological signs such as the penumbra and ghost signs assist in differentiating from other conditions. Advances in MRI techniques (e.g., zero time echo [ZTE] sequences) and the use of hybrid nuclear medicine procedures expand diagnostic capabilities, enhance surgical planning, and optimize therapy and follow-up.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"656-665"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Charcot's osteoarthropathy : How to identify a superimposed osteomyelitis?]","authors":"Karl-Friedrich Kreitner","doi":"10.1007/s00117-025-01488-0","DOIUrl":"10.1007/s00117-025-01488-0","url":null,"abstract":"<p><p>Charcot's osteoarthropathy is defined as an osteodestructive process characterized by peripheral neuropathy with lack of protective proprioception in which improper weight bearing leads to recurrent microtrauma, triggering of a proinflammatory process, pathological bone remodeling, joint instability, and subsequent joint destruction. The most common cause is diabetes which can lead to neuropathy over time. Magnetic resonance imaging is the most important imaging modality enabling subtle analysis of soft tissue and bony changes. Thus, it plays a key role in detection of early disease stages, assessment of disease activity during follow-up, and identification of superimposed infections and osteomyelitis. Soft tissue infections comprise cellulitis, phlegmons and abscesses. The ghost-sign is the most helpful diagnostic criterion for identification of osteomyelitis. The presence of a skin ulcer with surrounding soft tissue infection should give rise for a careful search for sinus tract and osseous involvement.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"666-673"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sacral fractures : Interface between spinal and pelvic ring injuries].","authors":"Lisa Goerens","doi":"10.1007/s00117-025-01501-6","DOIUrl":"https://doi.org/10.1007/s00117-025-01501-6","url":null,"abstract":"<p><strong>Aetiopathogenesis: </strong>Sacral fractures represent an often overlooked interface between spinal and pelvic ring injuries. They typically occur in high-energy trauma or in older patients with osteoporosis.</p><p><strong>Diagnostics: </strong>Due to their complex anatomy and deep location, they are difficult to detect using conventional radiography; thus, computed tomography (CT) is considered the diagnostic gold standard and allows precise fracture analysis. Magnetic resonance imaging (MRI) is particularly valuable for insufficiency or stress-related fractures to detect early bone marrow edema. Biomechanically, the sacrum plays a central role in transmitting load from the trunk to the lower limbs and protects critical neurovascular structures. Fractures can lead to significant instability and neurological deficits, especially when the sacral foramina (Denis zone II) or the sacral canal (Denis zone III) are involved. The AO classification distinguishes between stable (type A), potentially unstable (type B), and spinopelvic unstable (type C) fractures.</p><p><strong>Therapy: </strong>Therapy depends on fracture type, displacement, and neurological status. Nondisplaced fractures may be treated conservatively, whereas unstable or neurologically symptomatic injuries often require surgical stabilization. A structured radiology report that is understandable across specialties is crucial for effective treatment planning.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}