Radiologie (Heidelberg, Germany)最新文献

{"title":"[Pulmonary involvement in rare systemic diseases-part 2 : Pulmonary manifestations in the context of lysosomal and metabolic storage diseases, phacomatosis, and neuromuscular disorders].","authors":"Jasmin Happe, Thomas Frauenfelder","doi":"10.1007/s00117-025-01498-y","DOIUrl":"10.1007/s00117-025-01498-y","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary manifestations of systemic diseases represent a complex and diagnostically challenging field. While pulmonary involvement in immunological and hematological disorders is well described, lung involvement in rare genetic and congenital systemic diseases-such as systemic storage diseases, neuromuscular disorders, and phacomatoses-is only gradually gaining increased attention in radiological diagnostics.</p><p><strong>Results: </strong>The pulmonary component often manifests secondarily, frequently after years of progression and worsening of the underlying disease. Early detection of pulmonary manifestations is crucial for therapeutic management and the overall disease outcome. In imaging, high-resolution computed tomography (HRCT) plays a key role. As a technological innovation, photon-counting detector CT (PCD-CT) offers new diagnostic opportunities by providing significantly improved spatial resolution and an optimized signal-to-noise ratio compared to state-of-the-art energy-integrating detector CT (EID-CT) systems.</p><p><strong>Conclusion: </strong>The targeted application of these advanced CT technologies can thus not only improve the differential diagnostic classification of pulmonary manifestations but also enable timely therapeutic intervention.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"777-787"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Residency training in clinical practice].","authors":"Mina Soltani, Isabel Molwitz, Mike Notohamoprodjo","doi":"10.1007/s00117-025-01517-y","DOIUrl":"https://doi.org/10.1007/s00117-025-01517-y","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Postoperative imaging following spinal surgery for traumatic injuries].","authors":"A Haußmann, U Yilmaz","doi":"10.1007/s00117-025-01515-0","DOIUrl":"https://doi.org/10.1007/s00117-025-01515-0","url":null,"abstract":"<p><strong>Background: </strong>The number of surgically treated fractures has increased significantly in recent years and requires solid neuroradiological expertise.</p><p><strong>Objective: </strong>This article provides an overview of the most common early and late complications associated with surgical procedures, as well as their appropriate imaging-based diagnosis.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric spinal MRI for differentiating benign and malignant vertebral compression fractures.","authors":"Erdinç Tanlak, Rifat Özpar, Eren Tobcu, Mehmet Fatih İnecikli, Ömer Fatih Nas, Bahattin Hakyemez","doi":"10.1007/s00117-025-01512-3","DOIUrl":"https://doi.org/10.1007/s00117-025-01512-3","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the efficacy of multiparametric spinal MRI, utilizing conventional techniques, dynamic contrast-enhanced MRI, and diffusion MRI, in distinguishing between benign and malignant vertebral compression fractures.</p><p><strong>Material and methods: </strong>This retrospective study included 42 consecutive patients who underwent biopsy and pre-biopsy multiparametric spinal MRI. Patients under 18 or with non-diagnostic imaging were excluded. Images were evaluated blinded by two radiologists. Quantitative DWI and DCE-MRI parameters were analyzed using the Tofts model. Statistical tests included ANOVA, Mann-Whitney U, chi-square, and ROC analysis.</p><p><strong>Results: </strong>A total of 50 vertebral fractures from 42 patients (18 men, 24 women; mean age 55.3 ± 3.3 years; range 31-82) were included in the study. Among these lesions, 23 were classified as malignant and 27 as benign based on histopathological analysis. A statistically significant difference was found between benign and malignant groups in terms of in perfusion MR curve type, volume transfer constant (Ktrans), flux rate constant (Kep), and apparent diffusion coefficient (ADC) parameters (p = 0.000-0.02). In the ROC analysis, the highest sensitivity and specificity values were 73.9% and 77.8% for Ktrans, 88% and 77.8% for Kep, and 63% and 87% for ADC in distinguishing between benign and malignant vertebral compression fracture. In the multiparametric evaluation made according to ADC, Ktrans, and Kep cut-off values, the highest sensitivity and specificity values were 91.30% and 96.29%, respectively.</p><p><strong>Conclusion: </strong>Combining the information of quantitative ADC, Kep, and Ktrans analysis, multiparametric spinal MRI can differentiate benign from malignant compression fracture with high diagnostic accuracy. In this way, the need for invasive procedures to be performed only for diagnostic purposes can be reduced.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Pathological spine fractures].","authors":"Josef Mohamad","doi":"10.1007/s00117-025-01514-1","DOIUrl":"https://doi.org/10.1007/s00117-025-01514-1","url":null,"abstract":"<p><strong>Clinical issue: </strong>Pathological vertebral body fractures are nontraumatic fractures caused by metabolic diseases, tumor infiltration, inflammatory processes or other pathological changes. They often represent the first manifestation of an undiagnosed underlying condition. The clinical presentation is variable, most commonly involving acute back pain and, in some cases, neurological deficits up to paraplegia. Tumor-related fractures are often progressive and resistant to conservative treatment.</p><p><strong>Standard radiological methods: </strong>Diagnostic evaluation is stepwise, beginning with X‑ray (basic assessment), followed by computed tomography (detailed fracture and bone analysis), and magnetic resonance imaging (differentiation between benign vs. malignant causes, tumor infiltration, and spinal cord compression).</p><p><strong>Practical recommendations: </strong>Pathological vertebral body fractures should always be regarded as a potential first symptom of a serious underlying disease and must be promptly evaluated. This includes a thorough medical history, clinical examination, and appropriate stepwise imaging diagnostics. Therapeutic management depends on the underlying condition and the extent of the fracture, ranging from conservative treatment to surgical intervention.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine and deep learning for MRI-based quantification of liver iron overload: a systematic review and meta-analysis.","authors":"Mohammadreza Elhaie, Abolfazl Koozari, Qurain Turki Alshammari","doi":"10.1007/s00117-025-01513-2","DOIUrl":"https://doi.org/10.1007/s00117-025-01513-2","url":null,"abstract":"<p><strong>Background: </strong>Liver iron overload, associated with conditions such as hereditary hemochromatosis and β‑thalassemia major, requires accurate quantification of liver iron concentration (LIC) to guide timely interventions and prevent complications. Magnetic resonance imaging (MRI) is the gold standard for noninvasive LIC assessment, but challenges in protocol variability and diagnostic consistency persist. Machine learning (ML) and deep learning (DL) offer potential to enhance MRI-based LIC quantification, yet their efficacy remains underexplored.</p><p><strong>Objective: </strong>This systematic review and meta-analysis evaluates the diagnostic accuracy, algorithmic performance, and clinical applicability of ML and DL techniques for MRI-based LIC quantification in liver iron overload, adhering to PRISMA guidelines.</p><p><strong>Methods: </strong>A comprehensive search across PubMed, Embase, Scopus, Web of Science, Cochrane Library, and IEEE Xplore identified studies applying ML/DL to MRI-based LIC quantification. Eligible studies were assessed for diagnostic accuracy (sensitivity, specificity, AUC), LIC quantification precision (correlation, mean absolute error), and clinical applicability (automation, processing time). Methodological quality was evaluated using the QUADAS‑2 tool, with qualitative synthesis and meta-analysis where feasible.</p><p><strong>Results: </strong>Eight studies were included, employing algorithms such as convolutional neural networks (CNNs), radiomics, and fuzzy C‑mean clustering on T2*-weighted and multiparametric MRI. Pooled diagnostic accuracy from three studies showed a sensitivity of 0.79 (95% CI: 0.66-0.88) and specificity of 0.77 (95% CI: 0.64-0.86), with an AUC of 0.84. The DL methods demonstrated high precision (e.g., Pearson's r = 0.999) and automation, reducing processing times to as low as 0.1 s/slice. Limitations included heterogeneity, limited generalizability, and small external validation sets.</p><p><strong>Conclusion: </strong>Both ML and DL enhance MRI-based LIC quantification, offering high accuracy and efficiency. Standardized protocols and multicenter validation are needed to ensure clinical scalability and equitable access.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between masseter and temporal muscle measurements and sarcopenia and nutritional status in older adults.","authors":"Bahar Atasoy, Serdar Balsak, Alpay Alkan, Zeynep Donmez, Lee Smith, Fatma Çelik Yabul, Ozlem Toluk, Fazilhan Altintas, Yagmur Basak Polat, Pinar Soysal","doi":"10.1007/s00117-025-01504-3","DOIUrl":"https://doi.org/10.1007/s00117-025-01504-3","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to investigate the relationship between temporal muscle thickness (TMT) as well as temporal (TMA) and masseter muscle (MMA) area with nutritional status and sarcopenia in older individuals.</p><p><strong>Methods: </strong>This was a retrospective cross-sectional study. A total of 275 participants were evaluated to establish comprehensive geriatric assessment guidelines. Axial T1-weighted magnetic resonance imaging (MRI) was used for the measurement of TMT, TMA, and MMA. The Mini Nutritional Assessment, European Working Group on Sarcopenia in Older People (EWGSOP2) criteria, the Council on Nutrition Appetite Questionnaire, and the Eating Assessment Tool (EAT-10) scale were used to assess nutritional status, probable sarcopenia, and loss of appetite and dysphagia, respectively. Comparisons of continuous variables associated with nutritional analysis and sarcopenia were analyzed with the Mann-Whitney U test. Linear regression analyses were performed using the enter method, and dummy coding was used.</p><p><strong>Results: </strong>The mean age of participants was 82.4 ± 6.08 years. Overall, 14% were diagnosed as having malnutrition, and 40% patients were diagnosed with sarcopenia. The right TMT, left TMT, TMA, MMA, and mean_TMT values were significantly associated with malnutrition and sarcopenia (p < 0.05). A strong positive correlation was also found between the right TMT, left TMT, mean_TMT, TMA, MMA, and decreased appetite scores, calf and midarm circumference, and dominant hand grip score (p < 0.05), but no significant correlation was found between dysphagia and MRI measurements.</p><p><strong>Conclusion: </strong>Sarcopenia and malnutrition are associated with a decrease in temporal and masseter muscle area in older patients. There is also a connection between loss of appetite, indicators of decreased muscle strength and mass, and the weakening of the two muscles.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[SAPHO-Synovitis, acne, pustulosis, hyperosteosis, osteitis].","authors":"N Hesse, B Hoppe, P Reidler, R Schmitt","doi":"10.1007/s00117-025-01487-1","DOIUrl":"10.1007/s00117-025-01487-1","url":null,"abstract":"<p><strong>Clinical/methodological problem: </strong>SAPHO (synovitis, acne, pustulosis, hyperosteosis, osteitis) is a rare rheumatological disease characterized by combined osteoarticular and dermatological manifestations. Due to the nonspecific clinical presentation and skin findings, which may occur nonsimultaneously to the osteoarticular manifestations, diagnosis is usually delayed. Imaging plays a crucial role in identifying characteristic changes and distinguishing from differential diagnoses.</p><p><strong>Standard radiological procedures: </strong>X‑ray diagnostics, computed tomography (CT), and skeletal scintigraphy are established procedures for detecting typical osseous changes such as hyperostosis, sclerosis, and osteitis. Magnetic resonance imaging (MRI) allows early detection of inflammatory bone and soft tissue changes.</p><p><strong>Methodological innovations/performance: </strong>Whole-body MRI is used for the systematic detection of multifocal lesions. Compared to scintigraphy, MRI offers the possibility of differentiating between active and inactive lesions without the use of ionizing radiation.</p><p><strong>Achievements: </strong>Whole-body MRI is an important addition to conventional methods, especially for the early and noninvasive assessment of active disease processes and is an integral part of diagnostic evaluation.</p><p><strong>Recommendation for practice: </strong>In cases where the differential diagnosis is unclear, histological evaluation of the bone lesions must be performed.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"681-687"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cervical spine fractures].","authors":"Frederik Fries, Umut Yilmaz","doi":"10.1007/s00117-025-01508-z","DOIUrl":"https://doi.org/10.1007/s00117-025-01508-z","url":null,"abstract":"<p><strong>Background: </strong>Cervical spine injuries are a common and potentially serious injury in emergency medicine. Due to the complex anatomical relationships and the proximity to the spinal cord, early and targeted imaging is essential for accurate diagnosis and further management.</p><p><strong>Objective: </strong>This article provides a practice-oriented overview of the classification, imaging diagnostics, and clinical relevance of cervical spine fractures.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitteilungen des Berufsverbandes der Deutschen Radiologie.","authors":"","doi":"10.1007/s00117-025-01510-5","DOIUrl":"https://doi.org/10.1007/s00117-025-01510-5","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":"65 9","pages":"719-728"},"PeriodicalIF":0.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}