Radiologie (Heidelberg, Germany)最新文献

{"title":"Mitteilungen des Berufsverbandes der Deutschen Radiologie.","authors":"","doi":"10.1007/s00117-026-01615-5","DOIUrl":"https://doi.org/10.1007/s00117-026-01615-5","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":"66 5","pages":"413-429"},"PeriodicalIF":0.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Transarterial periarticular embolization as a treatment option for chronic joint pain].","authors":"Elif Can, Martin Jonczyk, Katharina Vogt, Wibke Uller","doi":"10.1007/s00117-026-01611-9","DOIUrl":"https://doi.org/10.1007/s00117-026-01611-9","url":null,"abstract":"<p><strong>Clinical issue: </strong>Osteoarthritis-related chronic joint pain substantially impairs function and quality of life. A clinically relevant subgroup of patients remains insufficiently controlled by conservative care and is not yet eligible for, or declines, arthroplasty (\"treatment gap\").</p><p><strong>Standard treatment: </strong>First-line management includes weight reduction and physiotherapy, analgesics/nonsteroidal anti-inflammatory drugs (NSAIDs), intra-articular injections, and-when indicated-surgical options up to joint replacement.</p><p><strong>Treatment innovations: </strong>Transarterial periarticular embolization (TAPE) targets abnormal periarticular neovascularity/hypervascularity via superselective, blush-guided devascularization using temporary crystalline agents or resorbable/permanent microspheres.</p><p><strong>Diagnostic work-up: </strong>Accurate pain localization to the target joint and radiographic osteoarthritis (OA) grading are mandatory. Magnetic resonance imaging (MRI)/ultrasound may support selection by demonstrating inflammatory activity (synovitis/hypervascularity). Angiography identifies the pathological blush as the procedural endpoint.</p><p><strong>Evidence: </strong>Across studies, technical success is near 100% with clinically meaningful improvements (typically ~30-40 point pain reduction on a 0-100 visual analog scale) and gains in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)/Knee Injury and Osteoarthritis Outcome Score (KOOS); however, sham-controlled randomized controlled trials (RCTs) show mixed results. Adverse events are uncommon and mainly mild/self-limited; major complications are rare.</p><p><strong>Conclusion: </strong>TAPE is a promising minimally invasive option, but its incremental benefit over placebo and optimal selection criteria require confirmation.</p><p><strong>Practical recommendations: </strong>Consider TAPE in specialized centers for refractory mild-to-moderate OA (strongest evidence for the knee; emerging data for hip/hand), using standardized protocols, particle sizes ≥ 100 µm when applicable, and strict nontarget prevention (e.g., skin cooling).</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Imaging of visceral, retroperitoneal, and pelvic soft-tissue sarcomas : Review].","authors":"Aleksandar Milosevic, Michal-Kamil Chodyla, Rainer Hamacher, Johann Moritz Kaths, Johannes Haubold, Lale Umutlu","doi":"10.1007/s00117-026-01612-8","DOIUrl":"https://doi.org/10.1007/s00117-026-01612-8","url":null,"abstract":"<p><strong>Background: </strong>Abdominal and retroperitoneal sarcomas are rare but prognostically relevant tumors that pose significant diagnostic challenges due to their size and proximity to critical anatomical structures. Cross-sectional imaging is crucial for detection, characterization, staging, and treatment planning.</p><p><strong>Objective: </strong>To present the current standards of cross-sectional imaging and to convey relevant aspects for radiological assessment based on established guidelines.</p><p><strong>Methods: </strong>Summary of the morphological characteristics, recommendations for imaging and resectability criteria based on current guidelines and published literature.</p><p><strong>Results: </strong>Magnetic resonance imaging (MRI) and computed tomography (CT) are indispensable for the assessment of abdominal and retroperitoneal sarcomas, especially with regard to organ and vessel relationships. MRI offers significant advantages over CT in the pelvis and for functional analysis. Typical patterns such as fat content, dedifferentiated areas, or infiltration support entity assessment and therapy planning.</p><p><strong>Conclusion: </strong>Standardized, guideline-based imaging is essential for diagnosis, treatment planning, and follow-up care and should be performed in interdisciplinary sarcoma centers.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147791586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroimaging features of EBV-associated primary central nervous system lymphoproliferative disorder in HIV-positive individuals.","authors":"Hui Chen, Chun-Shuang Guan, Ru-Ming Xie, Jia-Min Chen, Bo Liang, Jing-Jing Li","doi":"10.1007/s00117-026-01609-3","DOIUrl":"https://doi.org/10.1007/s00117-026-01609-3","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the current study was to describe neuroimaging findings of Epstein-Barr virus (EBV)-associated primary central nervous system lymphoproliferative disorder (PCNS-LPD) in human immunodeficiency virus (HIV)-positive individuals.</p><p><strong>Methods: </strong>The clinical data of four HIV-positive patients with confirmed EBV-associated PCNS-LPD were retrospectively analyzed from November 2018 to August 2024. All patients had undergone magnetic resonance imaging (MRI) examinations. The location, signal intensity, and enhancement pattern of the lesions on MRI were retrospectively evaluated.</p><p><strong>Results: </strong>The pathological diagnosis of EBV-associated PCNS-LPD was made in all four patients, in two cases by surgery and in two by biopsy. All four patients presented with limb motor dysfunction, and three had dizziness or headache. On MRI, lesions were located in the periventricular white matter in three patients; they involved the left cerebral peduncle and basal ganglia in two patients, the medulla oblongata in two patients, the right cerebellar peduncle and splenium of the corpus callosum in one patient, and the cortex and subcortex in one patient. All lesions showed hypointense to isointense signal intensity (SI) on T1-weighted imaging and isointense to hyperintense SI on T2-weighted imaging, as well as exhibiting restricted diffusion in the peripheral portions of the lesions. All lesions showed either ring-like or nodular inhomogeneous enhancement.</p><p><strong>Conclusion: </strong>In patients with HIV/acquired immune deficiency syndrome (AIDS) and EBV infection, multiple lesions in the periventricular regions and other intracranial sites should raise suspicion for EBV-associated PCNS-LPD. Although imaging findings may provide some evidence of EBV-associated PCNS-LPD, a differential diagnosis remains necessary.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Susceptibility-weighted imaging in acute ischemic stroke: correlation of susceptibility and prominent vessel signs with clinical severity.","authors":"Başak Atalay, Canberk Orundaş, Hüseyin Yıldız, Umut Perçem Orhan Söylemez","doi":"10.1007/s00117-026-01610-w","DOIUrl":"https://doi.org/10.1007/s00117-026-01610-w","url":null,"abstract":"<p><strong>Purpose: </strong>Susceptibility-weighted imaging (SWI) has emerged as a valuable tool in the evaluation of acute ischemic stroke. This study aimed to assess the correlation between the susceptibility vessel sign (SVS) and the National Institutes of Health Stroke Scale (NIHSS) scores, and as well as to explore the association between the grade of the prominent vessel sign (PVS) and clinical outcomes.</p><p><strong>Methods: </strong>The study population comprised consecutive patients with ischemic stroke evaluated at our institution over a 6-month period. A total of 124 patients (82 with anterior and 42 with posterior circulation stroke) were evaluated for the presence of the SVS and for thrombus length on SWI. Patients with anterior circulation stroke were further classified according to the grade of PVS. Admission and discharge NIHSS scores were also recorded. Associations between SWI findings, NIHSS scores, and treatment modality were assessed using correlation and group comparison analyses.</p><p><strong>Results: </strong>The mean age of the patients was 71.5 ± 13.8 years (range: 23-100). Patients with SVS had significantly higher admission NIHSS scores (p = 0.041), and SVS was more frequently observed in those with prominent veins (p < 0.001). The PVS grade correlated with both admission and discharge NIHSS scores (p = 0.005 and p < 0.001, respectively). Patients with higher PVS grades showed less improvement in NIHSS scores. Endovascular treatment was associated with a significantly greater reduction in NIHSS scores in the overall study population (p = 0.019).</p><p><strong>Conclusion: </strong>Susceptibility-weighted imaging provides essential information in acute ischemic stroke, with assessment of SVS presence and PVS grading serving as imaging biomarkers predicting clinical severity.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal large language models in brain tumor imaging: clinical applications and future perspectives.","authors":"Yixin Wang, Tao Ma, Hongzhi Wang","doi":"10.1007/s00117-026-01608-4","DOIUrl":"https://doi.org/10.1007/s00117-026-01608-4","url":null,"abstract":"<p><p>The use of multimodal data is essential for the precise diagnosis and treatment of brain tumors. In this context, multimodal data encompass multisequence magnetic resonance imaging, computed tomography, positron emission tomography, histopathological images, molecular and genomic profiles, structured clinical variables, and radiological reports. With the rapid advancement of artificial intelligence, integrating these heterogeneous data sources has become a central research direction for improving diagnostic accuracy, prognostic assessment, and therapeutic decision-making in neuro-oncology. However, substantial discrepancies exist across data modalities in terms of spatial resolution, semantic representation, and measurement scales, posing significant challenges for effective cross-modal integration. Multimodal large language models (MLLMs) enhance both interpretative and generative capabilities by jointly modeling visual, textual, and structured data, thereby offering a unified framework for addressing these challenges in brain tumor analysis. This review provides a comprehensive overview of MLLMs, covering their methodological foundations, representation learning strategies, and cross-modal alignment mechanisms. We further summarize their applications in both research and emerging clinical settings, including diagnosis support, prognosis prediction, treatment planning assistance, and radiology report generation. Finally, we discuss current limitations, such as data scarcity, interpretability constraints, and clinical deployment barriers, and outline future directions toward robust, explainable, and clinically translatable MLLM systems in neuro-oncology.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Transarterial microembolization in tendinopathies : Overview and current state of research].","authors":"A Taheri Amin, Peter Minko","doi":"10.1007/s00117-026-01604-8","DOIUrl":"https://doi.org/10.1007/s00117-026-01604-8","url":null,"abstract":"<p><strong>Background: </strong>Chronic tendinopathies are common causes of persistent musculoskeletal pain. In refractory cases, pathological hypervascularization and neo-innervation play a key role in pain generation. Transarterial microembolization (TAME) aims to reduce this abnormal vascularity using a minimally invasive approach.</p><p><strong>Purpose: </strong>This review summarizes current evidence regarding the efficacy and safety of TAME in selected tendinopathies.</p><p><strong>Materials and methods: </strong>A narrative review of recent literature on TAME for adhesive capsulitis, medial and lateral epicondylitis, Achilles tendinopathy, and plantar fasciitis was conducted, focusing on technical aspects, embolic agents, and clinical outcomes.</p><p><strong>Results: </strong>Available studies consistently demonstrate significant pain reduction and functional improvement following TAME across all indications. The strongest evidence exists for adhesive capsulitis and Achilles tendinopathy, with reported clinical success rates of approximately 80-90%. Procedures are typically performed catheter-guided using a superselective approach and temporary embolic agents, most commonly imipenem/cilastatin. No major complications have been reported.</p><p><strong>Conclusion: </strong>TAME represents a safe and effective minimally invasive treatment option for selected refractory tendinopathies and may bridge the gap between conservative management and surgery. Further randomized controlled trials are required to define long-term outcomes and optimal patient selection.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147679452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[An unusual mass in the breast].","authors":"A Ruiu, N Cortellini, S Stuppner, P Auricchio, M Lüthy, C Mian, C Mayr, R Polato, F Ferro","doi":"10.1007/s00117-026-01603-9","DOIUrl":"https://doi.org/10.1007/s00117-026-01603-9","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Multiple soft tissue swellings : Computed tomography as the basis for complex tumour detection].","authors":"Melisa Özgüneyli, Daaje Reents, Suzan Abu Zanat, Sophia Engel","doi":"10.1007/s00117-026-01590-x","DOIUrl":"https://doi.org/10.1007/s00117-026-01590-x","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Trinucleotide repeat disorders].","authors":"Armin Bachhuber","doi":"10.1007/s00117-026-01561-2","DOIUrl":"10.1007/s00117-026-01561-2","url":null,"abstract":"<p><strong>Background: </strong>Trinucleotide disorders are a heterogeneous group that lead to neurodegeneration with severe motor and psychiatric impairments. Neither the clinical presentation nor the radiological signs are specific, leading to frequent misdiagnoses.</p><p><strong>Objectives: </strong>Neuroradiological signs in trinucleotide disorders.</p><p><strong>Methods: </strong>A search in pubmed.gov was conducted to identify studies reflecting the current state of knowledge.</p><p><strong>Results: </strong>An overview of the most common trinucleotide disorders and their characteristic radiological features is provided.</p><p><strong>Conclusion: </strong>As in many degenerative diseases, imaging represents only one piece of the puzzle and primarily provides guidance as to the diagnostic direction.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"258-263"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146204092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}