{"title":"[Radiological imaging of spinal trauma in special situations].","authors":"Umut Yilmaz, Malvina Garner","doi":"10.1007/s00117-025-01516-z","DOIUrl":"https://doi.org/10.1007/s00117-025-01516-z","url":null,"abstract":"<p><p>Spinal trauma is rare but associated with considerable morbidity and mortality. Its diagnostic evaluation poses significant challenges for radiologists, particularly in specific patient groups and clinical scenarios. This review article highlights the role of computed tomography and magnetic resonance imaging in acute and specialized imaging of spinal trauma under particular circumstances. Special attention is given to pediatric injuries, normal variants (e.g., pseudosubluxation, os odontoideum), discoligamentous injuries, age- and medication-related osteoporotic fractures, imaging in pregnant patients with strict radiation protection requirements, as well as complex situations such as polytrauma, traumatic brain injury, or coagulopathies. In addition, pathological fractures caused by tumors or infections and imaging in postoperative patients are discussed. Classification systems such as Thoracolumbar Injury Classification and Severity Score (TLICS), AO Spine score, Osteoporotic Fracture (OF) score, and Spinal Instability Neoplastic Score (SINS) provide a structured basis for therapeutic decision-making. Radiologists play a key role, as imaging not only makes the diagnosis, but also directly influences classification and treatment planning. Future developments such as AI-supported fracture detection, dual-energy CT and artefact-reduced MRI sequences will further improve diagnostics.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pulmonary involvement in rare systemic diseases-part 1 : Pulmonary manifestations in the context of hematological, immunological, histiocytic, and hepatological diseases and chronic inflammatory bowel disease].","authors":"Jasmin Happe, Thomas Frauenfelder","doi":"10.1007/s00117-025-01497-z","DOIUrl":"10.1007/s00117-025-01497-z","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary manifestations occur in a wide range of multisystemic diseases and can affect the lung parenchyma, airways, vascular system, and respiratory musculature in various ways. In particular, severe and potentially life-threatening pulmonary complications are of major concern in systemic conditions such as immunological and hematological disorders. The increasing incidence of hematological, gastrointestinal, and hepatological diseases in recent years-driven in part by lifestyle factors in Western industrialized nations-highlights the growing clinical relevance of these entities and the need for a comprehensive understanding of their pulmonary manifestations. Additional diagnostic and therapeutic challenges arise from drug-induced lung injury and late complications of therapy, such as those following stem cell transplantation.</p><p><strong>Results: </strong>High-resolution computed tomography (HRCT) plays a pivotal role in this context. It allows for the early detection of characteristic pulmonary abnormalities and thus forms the basis for timely therapeutic intervention.</p><p><strong>Conclusion: </strong>Targeted HRCT imaging is therefore crucial to improving clinical outcomes and preserving the quality of life in affected patients.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"766-776"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sigmund Stuppner, F Baessato, Laurjan Hoxha, F Ferro
{"title":"[A special chamber view].","authors":"Sigmund Stuppner, F Baessato, Laurjan Hoxha, F Ferro","doi":"10.1007/s00117-025-01511-4","DOIUrl":"10.1007/s00117-025-01511-4","url":null,"abstract":"","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"788-792"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lukas Ebner, Helmut Prosch, Adrian Huber, Justus Roos
{"title":"[Sarcoidosis].","authors":"Lukas Ebner, Helmut Prosch, Adrian Huber, Justus Roos","doi":"10.1007/s00117-025-01503-4","DOIUrl":"10.1007/s00117-025-01503-4","url":null,"abstract":"<p><strong>Clinical/methodical issue: </strong>Sarcoidosis is a systemic inflammatory disease of unknown cause, characterized by the formation of noncaseating epithelioid cell granulomas, which can potentially affect nearly every organ. The lungs and mediastinal lymph nodes are most commonly affected-with granulomatous involvement found in approximately 90% of cases. Typically, younger adults are affected by sarcoidosis. The clinical picture and the course of the disease can vary significantly, which is why it is also referred to as the \"great mimicker\". The aim of this review is to provide an overview on the imaging findings in patients with sarcoidosis. In addition, the current diagnostic and therapeutic management will be elaborated.</p><p><strong>Standard radiological methods: </strong>The conventional chest radiograph has long been considered a fundamental examination in suspected sarcoidosis. Traditionally, staging is performed according to the Scadding classification (stages 0-IV). However, computed tomography (CT) is increasingly used due to its higher accuracy and availability.</p><p><strong>Methodical innovations: </strong>Recently, seven dedicated radiologic phenotypes of sarcoidosis have been identified on CT, comprising four nonfibrotic and three fibrotic subtypes. Given the superior accuracy of CT and its potential role in therapy monitoring, baseline high-resolution CT (HRCT) is increasingly recommended.</p><p><strong>Practical recommendations: </strong>Sarcoidosis is an inflammatory multisystem disease involving the lungs and thoracic lymph nodes in approximately 90% of cases. Current guidelines still recommend chest radiography as the initial imaging modality for diagnosis and staging; however, CT is increasingly being used.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"756-765"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna M Hunkemöller, Hoen-Oh Shin, Cornelia Schaefer-Prokop
{"title":"[Pulmonary manifestations of ANCA-associated vasculitis in imaging].","authors":"Anna M Hunkemöller, Hoen-Oh Shin, Cornelia Schaefer-Prokop","doi":"10.1007/s00117-025-01507-0","DOIUrl":"10.1007/s00117-025-01507-0","url":null,"abstract":"<p><strong>Clinical/methodical issue: </strong>Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) such as granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA) are rare autoimmune diseases that frequently involve the lungs and may present with life-threatening complications. Their differentiation can be challenging due to overlapping clinical and radiological findings.</p><p><strong>Standard radiological methods: </strong>High-resolution computed tomography (HRCT) is the key imaging modality for detecting pulmonary changes such as nodules, ground-glass opacities, and consolidations. Chest X‑ray and contrast-enhanced computed tomography (CT) are also used.</p><p><strong>Methodical innovations: </strong>Newer techniques such as low-dose CT, perfusion CT, and structured serial imaging offer improved detection of diffuse alveolar hemorrhage (DAH), granulomatous inflammation, and airway involvement.</p><p><strong>Performance: </strong>HRCT achieves sensitivities up to 90% in pulmonary AAV manifestations like DAH. Specificity remains limited, requiring integration of clinical and serological findings. Advanced methods enhance lesion characterization and assessment of disease activity.</p><p><strong>Achievements: </strong>Radiology enables early identification of distinct pulmonary patterns (e.g., cavitary nodules in GPA, peripheral migratory consolidations in EGPA, perihilar DAH in MPA). Although not pathognomonic, imaging is highly valuable when interpreted in context.</p><p><strong>Practical recommendations: </strong>Diagnostic work-up is best conducted in interdisciplinary centers. HRCT should be performed in suspected pulmonary AAV. Contrast-enhanced CT is useful in suspected hemorrhage or necrosis. Radiological interpretation must be combined with clinical data, ANCA serology, and potentially histology.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"748-755"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Connective tissue disease-associated interstitial lung diseases : A pattern-based approach to diagnosis].","authors":"Rebecca Mura, Daria Kifjak, Kastriot Kastrati, Nino Bogveradze, Lucian Beer, Helmut Prosch","doi":"10.1007/s00117-025-01492-4","DOIUrl":"10.1007/s00117-025-01492-4","url":null,"abstract":"<p><p>Connective tissue diseases (CTD) encompass a heterogeneous group of systemic immune-mediated disorders affecting connective tissue throughout the body. Pulmonary involvement is a common and clinically significant manifestation of CTD, with interstitial lung disease (ILD) representing a major contributor to both morbidity and mortality. Therefore, early detection of CTD-ILD is critical, and a multidisciplinary approach is paramount for both diagnosis and patient management. In this context, high-resolution computed tomography (HRCT) plays a pivotal role not only in recognizing characteristic ILD patterns but also in monitoring disease progression and guiding further management. Although the most frequent imaging pattern in CTD-ILD is nonspecific interstitial pneumonia (NSIP), the spectrum of pulmonary manifestations is complex and heterogeneous. Other patterns such as usual interstitial pneumonia (UIP), organizing pneumonia (OP), lymphocytic interstitial pneumonia (LIP), and diffuse alveolar damage (DAD) can also occur, showing distinct associations with specific CTD. Moreover, overlap and transition between patterns are not uncommon, further complicating the diagnostic process. This review aims to provide a comprehensive overview of the most relevant pulmonary manifestations of CTD, particularly ILD, with a focus on HRCT-based pattern recognition in order to enhance radiologist's familiarity with their spectrum of imaging appearances.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"734-747"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pulmonary involvement in systemic diseases : Possibilities and limitations of radiology].","authors":"Okka Hamer","doi":"10.1007/s00117-025-01491-5","DOIUrl":"10.1007/s00117-025-01491-5","url":null,"abstract":"<p><p>The diagnosis of pulmonary involvement in systemic diseases presents a major challenge. This challenge can only be met through close interdisciplinary collaboration and by discussing all available examination results, including radiological findings, in a comprehensive and integrative manner. The role of the radiologist is to possess in-depth knowledge of systemic diseases and their pulmonary manifestations. The radiological report should not be limited to a mere description of the morphological pattern. In appropriate contexts, the possibility of systemic disease should be indicated, and, where applicable, recommendations for further diagnostic measures ideally by pulmonologists or rheumatologists should be provided.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"731-733"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144981831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Spinal dural arteriovenous malformations].","authors":"Wolfgang Reith, Anne Udelhoven, Michael Kettner","doi":"10.1007/s00117-025-01509-y","DOIUrl":"10.1007/s00117-025-01509-y","url":null,"abstract":"<p><p>Vascular malformations of the spinal cord are a rare and complex clinical entity and can lead to severe morbidity with progressive spinal cord symptoms if not treated properly. In early stages the disease is characterized by slowly progressive, nonspecific symptoms, such as gait disturbance, paresthesia, diffuse sensory symptoms and radicular pain. In the late stages, bowel and bladder incontinence, erectile dysfunction, and urinary retention may develop. In recent decades the understanding and treatment of spinal vascular malformations have improved with the evolution of diagnostic tools and treatment modalities; however, it is still difficult to treat these cases because of the complexity of the pathology. All spinal dural arteriovenous fistulas (sdAVF) are most likely acquired; however, the exact etiology remains unknown. They typically present as a progressive myelopathy and have a poor prognosis if left untreated. Delayed diagnosis and intervention are associated with an increased risk of neurological deficits and a reduced likelihood of recovery. The general aim of treatment is disconnection of the arteriovenous shunt, which can be achieved by either open surgery or endovascular techniques. The surgical treatment of sdAVFs should be regarded as a combination of techniques with the shared goal of disconnecting the fistula.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"793-804"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pulmonary involvement in rare systemic diseases-part 2 : Pulmonary manifestations in the context of lysosomal and metabolic storage diseases, phacomatosis, and neuromuscular disorders].","authors":"Jasmin Happe, Thomas Frauenfelder","doi":"10.1007/s00117-025-01498-y","DOIUrl":"10.1007/s00117-025-01498-y","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary manifestations of systemic diseases represent a complex and diagnostically challenging field. While pulmonary involvement in immunological and hematological disorders is well described, lung involvement in rare genetic and congenital systemic diseases-such as systemic storage diseases, neuromuscular disorders, and phacomatoses-is only gradually gaining increased attention in radiological diagnostics.</p><p><strong>Results: </strong>The pulmonary component often manifests secondarily, frequently after years of progression and worsening of the underlying disease. Early detection of pulmonary manifestations is crucial for therapeutic management and the overall disease outcome. In imaging, high-resolution computed tomography (HRCT) plays a key role. As a technological innovation, photon-counting detector CT (PCD-CT) offers new diagnostic opportunities by providing significantly improved spatial resolution and an optimized signal-to-noise ratio compared to state-of-the-art energy-integrating detector CT (EID-CT) systems.</p><p><strong>Conclusion: </strong>The targeted application of these advanced CT technologies can thus not only improve the differential diagnostic classification of pulmonary manifestations but also enable timely therapeutic intervention.</p>","PeriodicalId":74635,"journal":{"name":"Radiologie (Heidelberg, Germany)","volume":" ","pages":"777-787"},"PeriodicalIF":0.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}