[Pulmonary involvement in rare systemic diseases-part 1 : Pulmonary manifestations in the context of hematological, immunological, histiocytic, and hepatological diseases and chronic inflammatory bowel disease].

Background: Pulmonary manifestations occur in a wide range of multisystemic diseases and can affect the lung parenchyma, airways, vascular system, and respiratory musculature in various ways. In particular, severe and potentially life-threatening pulmonary complications are of major concern in systemic conditions such as immunological and hematological disorders. The increasing incidence of hematological, gastrointestinal, and hepatological diseases in recent years-driven in part by lifestyle factors in Western industrialized nations-highlights the growing clinical relevance of these entities and the need for a comprehensive understanding of their pulmonary manifestations. Additional diagnostic and therapeutic challenges arise from drug-induced lung injury and late complications of therapy, such as those following stem cell transplantation.

Results: High-resolution computed tomography (HRCT) plays a pivotal role in this context. It allows for the early detection of characteristic pulmonary abnormalities and thus forms the basis for timely therapeutic intervention.

Conclusion: Targeted HRCT imaging is therefore crucial to improving clinical outcomes and preserving the quality of life in affected patients.