Psychiatry research case reports最新文献_第4页

‘I wouldn't have become addicted to fruit machines if it wasn't for coin pushers’: A case report of adolescent coin pusher use leading to lifelong gambling-related harm “如果不是因为推币机，我不会对水果机上瘾”：一份青少年使用推币机导致终身赌博相关伤害的案例报告

Psychiatry research case reports Pub Date : 2025-01-12 DOI: 10.1016/j.psycr.2025.100246

Jamie Torrance , Jessica Smith , Philip Newall

{"title":"‘I wouldn't have become addicted to fruit machines if it wasn't for coin pushers’: A case report of adolescent coin pusher use leading to lifelong gambling-related harm","authors":"Jamie Torrance , Jessica Smith , Philip Newall","doi":"10.1016/j.psycr.2025.100246","DOIUrl":"10.1016/j.psycr.2025.100246","url":null,"abstract":"<div><div>While most previous adolescent gambling research focuses on the illegal use of age-restricted products, adolescents can also often gamble legally using machines such as coin pushers (aka ‘penny falls’ machines). Using a qualitative case report design, we use an in-depth interview to complement previous findings, which have associated recollected adolescent use of coin pusher machines with levels of adult gambling-related harm. We recruited a 57-year-old male with a history of significant gambling-related harm, whose initiation into gambling involved the adolescent use of coin pusher machines. The interview was audio recorded, transcribed, and analyzed using interpretative phenomenological analysis. Three themes were identified: the structural similarities between coin pushers and traditional gambling formats, the role of proximity and normalization in facilitating progression to riskier gambling, and the participant's suggestions for population-level harm prevention measures. This novel case report highlights how a person's lifelong struggles with severe gambling-related harms began with adolescent exposure to coin pusher machines. Greater awareness of this case could encourage more gamblers to share similar experiences, alongside helping to educate parents and policymakers about the potential harmful consequences of using coin pusher machines.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100246"},"PeriodicalIF":0.0,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Could psychedelics be useful in the treatment of patients with personality disorder? A case report of psychotherapy with concomitant use of psychedelics 迷幻药对治疗人格障碍患者有用吗？心理治疗同时使用致幻剂一例报告

Psychiatry research case reports Pub Date : 2025-01-08 DOI: 10.1016/j.psycr.2025.100245

Martin Blay , Inès Benmakhlouf , Mario Speranza

{"title":"Could psychedelics be useful in the treatment of patients with personality disorder? A case report of psychotherapy with concomitant use of psychedelics","authors":"Martin Blay , Inès Benmakhlouf , Mario Speranza","doi":"10.1016/j.psycr.2025.100245","DOIUrl":"10.1016/j.psycr.2025.100245","url":null,"abstract":"<div><div>Psychotherapy enhanced by psychedelics has recently been found to be helpful for the treatment of several psychiatric disorders, notably depressive disorders. However, it has only been considered scarcely in patients suffering from personality disorders. Here, we report the case of a 37 years-old woman suffering from severe mixed personality disorder and ADHD. Alongside the beginning of her GPM-based psychotherapeutic treatment, and despite our concerns, she started closely monitored psychedelic micro-dosing, using products bought online, punctuated by occasional macro-dosing After one-year of this psychotherapy associated with concomitant independent use of psychedelics, paranoid, narcissistic and borderline personality dimensions were largely improved, as well as emotion regulation, impulsivity, mentalization abilities, and social functioning. Given the actual evidence regarding the efficacy of psychedelics to improve the latter four dimensions, given the patient's reported experience, and despite important limits, we make the hypothesis that the concomitant use of psychedelics has enhanced psychotherapy efficacy. Overall, this case asks the question of the potential usefulness of psychedelics associated with psychotherapy in patients with PD. Further pilot studies should be conducted on this issue.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100245"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An actigraphy case series: Sleep disturbance associations with suicidal ideation, self-harm and desire to live 一个活动记录仪案例系列：睡眠障碍与自杀意念、自残和生存欲望的关联

Psychiatry research case reports Pub Date : 2025-01-04 DOI: 10.1016/j.psycr.2025.100244

Annabelle M. Mournet, Allison K. Ruork, Evan M. Kleiman, Shireen L. Rizvi

{"title":"An actigraphy case series: Sleep disturbance associations with suicidal ideation, self-harm and desire to live","authors":"Annabelle M. Mournet, Allison K. Ruork, Evan M. Kleiman, Shireen L. Rizvi","doi":"10.1016/j.psycr.2025.100244","DOIUrl":"10.1016/j.psycr.2025.100244","url":null,"abstract":"<div><h3>Introduction</h3><div>Sleep disturbances are a well-established suicide risk factor. This case series represents an investigation into the individual-level associations between objectively measured sleep using actigraphy and fatigue on next-day suicidal ideation, self-harm urges, and desire to be alive.</div></div><div><h3>Methods</h3><div>This case series utilizes data from seven adults with borderline personality disorder receiving dialectical behavioral therapy (DBT). Participants wore a Phillips HealthBand wearable device to collect actigraphy data and completed ecological momentary assessment (EMA). Data was collected for one week per month for each of the six months of treatment. We conducted a series of individual linear regressions.</div></div><div><h3>Results</h3><div>For participant 1, fatigue was associated with self-injury urges. Sleep duration and time in bed were predictive of desire to be alive. For participant 3, fatigue was associated with suicidal ideation. Sleep efficiency was predictive of desire to be alive. Participant 5′s WASO was predictive of suicidal ideation and desire to be alive. For participant 6, WASO predicted desire to be alive. For participant 7, fatigue was predictive of desire to be alive.</div></div><div><h3>Discussion</h3><div>This case series provides evidence that certain aspects of sleep, as measured by actigraphy, is predictive of SI, self-harm urges, and desire to be alive among certain DBT patients. Results points to the importance of examining actigraphy findings on an individual level. Future research should continue to utilize multimodal data to advance understanding of the associations between sleep metrics with STBs, as well as how to continue to best leverage actigraphy data in combination with other methodologies.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100244"},"PeriodicalIF":0.0,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The many faces of psilocybin-related psychosis: A case series 裸盖菇素相关精神病的多个方面：一个案例系列

Psychiatry research case reports Pub Date : 2024-12-07 DOI: 10.1016/j.psycr.2024.100243

Yumin Kim , Rachel Bigley , Aubrey DeVinney , Paul S. Nestadt

{"title":"The many faces of psilocybin-related psychosis: A case series","authors":"Yumin Kim , Rachel Bigley , Aubrey DeVinney , Paul S. Nestadt","doi":"10.1016/j.psycr.2024.100243","DOIUrl":"10.1016/j.psycr.2024.100243","url":null,"abstract":"<div><h3>Background</h3><div>Psilocybin use has been increasingly popular in the United States, and its use as a novel therapeutic treatment for psychiatric conditions has led to greater public acceptance as a recreational substance. Consequently, clinicians are faced with managing complications and adverse effects associated with psilocybin use.</div></div><div><h3>Basic Procedures/Main Findings</h3><div>We present three cases seen in a dual diagnosis inpatient psychiatry unit during a four-week period in 2023: Case 1: the case of intermittent psilocybin use associated with a particularly prolonged psychosis requiring treatment with higher doses and a longer course of neuroleptic medication; Case 2: the case of a short period of frequent psilocybin use culminating into increasing paranoia and a medically serious suicide attempt treated with neuroleptics; and Case 3: the case of long-term “microdosing” followed by mania-like symptoms including grandiosity, irritability, and physical aggression towards others, but with resolution of symptoms after discontinuing psilocybin use.</div></div><div><h3>Conclusions</h3><div>Amidst psilocybin's increasing prevalence and acceptance, clinicians are faced with managing the complications and adverse effects of psilocybin use with minimal guidelines or evidence. This case series aims to highlight varied presentations, management strategies, and treatment responses to contribute some insight into this unknown territory.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100243"},"PeriodicalIF":0.0,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Schema-therapeutic exposure for treatment resistant anxiety and obsessive-compulsive disorders: A multiple baseline case series design study 图式治疗暴露治疗难治性焦虑和强迫症：多基线病例系列设计研究

Psychiatry research case reports Pub Date : 2024-12-01 DOI: 10.1016/j.psycr.2024.100241

Nancy Peeters , Boris van Passel , Gert-Jan Hendriks , Eni Becker , Julie Krans

{"title":"Schema-therapeutic exposure for treatment resistant anxiety and obsessive-compulsive disorders: A multiple baseline case series design study","authors":"Nancy Peeters , Boris van Passel , Gert-Jan Hendriks , Eni Becker , Julie Krans","doi":"10.1016/j.psycr.2024.100241","DOIUrl":"10.1016/j.psycr.2024.100241","url":null,"abstract":"<div><div>Exposure is effective for patients with anxiety disorders or obsessive-compulsive disorders (OCD). Yet, a significant minority does not recover with current guideline treatments due to comorbid personality disorder symptoms. For these patients, no further guideline treatments exist. Schema therapy (ST) is an evidence-based treatment for personality disorders and integrating ST and exposure could provide a solution. We tested a new schema-therapeutic exposure treatment in patients with treatment-resistant anxiety or OCD. Using the latest methodological and statistical insights in a well-powered single-case experimental design (SCED; <em>N</em> = 6), we administered weekly measures of psychological malfunctioning, anxiety/OCD symptoms, and schema modes over the course of treatment (29–32 weeks). Schema-therapeutic exposure was effective for 33.33 % of our sample, with improvement on all or most outcome measures. Another 33.33 % demonstrated partial improvements, and 33.33 % remained stable. Given the historical chronicity of symptoms in our sample, these effects are highly encouraging. Secondary findings showed that changes in schema modes did not precede changes in anxiety/OCD symptoms or psychological malfunctioning, and that 66.66 % of the sample continued to improve in the second half of the treatment. Future research is wanted to unravel the interactive and additive effects of schema-therapeutic exposure to further optimize treatment.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"4 1","pages":"Article 100241"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143145845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic and management challenges of a patient with schizophrenia and comorbid anorexia nervosa 精神分裂症并发神经性厌食症患者的诊断和管理难题

Psychiatry research case reports Pub Date : 2024-11-20 DOI: 10.1016/j.psycr.2024.100240

Ho Teck Tan , Cecilia Sze Nga Kwok , Huei Yen Lee , Giles Ming Yee Tan

{"title":"Diagnostic and management challenges of a patient with schizophrenia and comorbid anorexia nervosa","authors":"Ho Teck Tan , Cecilia Sze Nga Kwok , Huei Yen Lee , Giles Ming Yee Tan","doi":"10.1016/j.psycr.2024.100240","DOIUrl":"10.1016/j.psycr.2024.100240","url":null,"abstract":"<div><div>The prevalence of comorbid schizophrenia in patients with eating disorders is between 3 and 10% while symptoms of anorexia nervosa has been observed in 1–4% of patients with schizophrenia. However, there is a lack of comprehensive studies available to better understand and manage this complex dual diagnosis at present.</div><div>Here, we present a case of treatment-resistant schizophrenia and comorbid anorexia nervosa in a young woman in a long-stay ward of a tertiary psychiatric hospital requiring 1-1 nursing care. She exhibited disordered eating behaviors, a distorted body image, and persistent food refusal. A diagnostic dilemma presented due to the overlap in symptomatology between her eating disorder-related restrictive behaviors and psychosis-driven food refusal. Efforts to engage her in various therapies for her anorexia nervosa has been hampered by her regressed and disorganized behavior, with concerns of the metabolic side effects of anti-psychotics potentially worsening her eating disorder cognitions. She required constant monitoring of her bloods and vitals due to her severely low body mass index (BMI). Different combinations of psychotropics, neurostimulation and psychotherapies were trialed with limited efficacy. The diagnostic overlap and treatment challenges highlights the need for interdisciplinary approaches and tailored management strategies for complex comorbid cases of schizophrenia and anorexia nervosa.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"3 2","pages":"Article 100240"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of eye movement desensitization and reprocessing in a person with dementia and post-traumatic stress disorder: A case report 对一名患有痴呆症和创伤后应激障碍的患者进行眼动脱敏和再处理的可行性：病例报告

Psychiatry research case reports Pub Date : 2024-11-13 DOI: 10.1016/j.psycr.2024.100239

J.E. Ruisch , M. van Kordenoordt , C. Steins , M.A.M.J. Daamen , K.R.J. Schruers , S. Sobczak , E.M.J. Gielkens

{"title":"Feasibility of eye movement desensitization and reprocessing in a person with dementia and post-traumatic stress disorder: A case report","authors":"J.E. Ruisch , M. van Kordenoordt , C. Steins , M.A.M.J. Daamen , K.R.J. Schruers , S. Sobczak , E.M.J. Gielkens","doi":"10.1016/j.psycr.2024.100239","DOIUrl":"10.1016/j.psycr.2024.100239","url":null,"abstract":"<div><h3>Introduction</h3><div>Post-traumatic stress disorder (PTSD) is an independent risk factor for dementia. Case reports of poor-moderate quality indicate the feasibility of Eye Movement Desensitization and Reprocessing (EMDR) sessions in this population but lack a detailed description of the treatment and its challenges.</div></div><div><h3>Goal</h3><div>This report aimed to provide a detailed description of the feasibility and challenges of EMDR for a person with dementia to assist in the first step toward recognizing and treating PTSD in people with dementia.</div></div><div><h3>Methods</h3><div>In this case study, we describe an 89-year-old nursing home resident with mild–moderate dementia and trauma related symptoms. EMDR treatment was indicated, and four sessions, according to a standard child/youth protocol, were applied. Debriefing questionnaires were completed by a psychologist after each EMDR session. To monitor the effect of the EMDR therapy, a structured interview exploring PTSD symptoms (TRADE- TRAuma and DEmentia interview) was conducted between the treatment sessions.</div></div><div><h3>Results</h3><div>The debriefing questionnaires showed that EMDR was well tolerated and experienced as pleasant, but some challenges occurred; During the EMDR sessions she was easily distracted, requested multiple breaks, and required the use of shorter sentences, with a more directive approach. PTSD symptoms of recurring memories and negative thoughts were reduced.</div></div><div><h3>Conclusions</h3><div>This case report provides a detailed description showing the feasibility of EMDR therapy for a person with PTSD and dementia. It appeared necessary to adjust the EMDR standard child/youth protocol to a further simplified form, due to the reduced concentration and endurance.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"3 2","pages":"Article 100239"},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142699514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expanding the role of metoclopramide in Tardive Dyskinesia: A case report 扩大甲氧氯普胺在迟发性运动障碍中的作用：病例报告

Psychiatry research case reports Pub Date : 2024-11-03 DOI: 10.1016/j.psycr.2024.100238

Evaristus Chino Ezema , Ngozi Akueme , Precious Okpechi , Omotola Emmanuel , Omosumwen Ede , Sanmi Michael Obe , Ndukaku Ogbonna , Maureen Obi , Nnenna Bessie Emejuru , Ogochukwu Agazie , Vivien Obitulata Ugwu , John Mmaduabuchi , Emmanuel Chiebuka , Valentine Keke , Chinenye Loveth Aleke

{"title":"Expanding the role of metoclopramide in Tardive Dyskinesia: A case report","authors":"Evaristus Chino Ezema , Ngozi Akueme , Precious Okpechi , Omotola Emmanuel , Omosumwen Ede , Sanmi Michael Obe , Ndukaku Ogbonna , Maureen Obi , Nnenna Bessie Emejuru , Ogochukwu Agazie , Vivien Obitulata Ugwu , John Mmaduabuchi , Emmanuel Chiebuka , Valentine Keke , Chinenye Loveth Aleke","doi":"10.1016/j.psycr.2024.100238","DOIUrl":"10.1016/j.psycr.2024.100238","url":null,"abstract":"<div><div>Tardive dyskinesia is a medication-induced movement disorder commonly caused by the blockade or depletion of dopamine in the basal ganglia, seen mostly in the psychiatric setting following prolonged use of antipsychotic medications. It is also reported in other settings where patients receive non-antipsychotic medications. The prevalence of tardive dyskinesia varies across age, gender, and race, with women of middle age being more prone to develop tardive dyskinesia more than men. Therefore, we report a case of tardive dyskinesia, post-delivery, in an African woman, who received metoclopramide as part of premedication for spinal anesthesia for an emergency cesarean delivery. The debriefing period following the resolution of the symptoms offered a clue to prior utilization of metoclopramide for the treatment of hyperemesis gravidarum as provided by the patient's family. Hence, fulfilling the diagnostic criteria of prolong usage of the implicating agent.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"3 2","pages":"Article 100238"},"PeriodicalIF":0.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142660221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A unique case of iatrogenic hebephiliac behavior emerging late in life in a patient with Gordon Holmes Syndrome 戈登-霍姆斯综合征患者晚年出现先天性虹膜睫状体行为的独特病例

Psychiatry research case reports Pub Date : 2024-09-29 DOI: 10.1016/j.psycr.2024.100237

Riccardo Loconte , Gianluca Sesso , Cristina Scarpazza , Pietro Pietrini

{"title":"A unique case of iatrogenic hebephiliac behavior emerging late in life in a patient with Gordon Holmes Syndrome","authors":"Riccardo Loconte , Gianluca Sesso , Cristina Scarpazza , Pietro Pietrini","doi":"10.1016/j.psycr.2024.100237","DOIUrl":"10.1016/j.psycr.2024.100237","url":null,"abstract":"<div><h3>Background</h3><div>Pedophilic or hebephiliac behavior is defined iatrogenic when emerging for the first time as a side effect of medications. To date, pedophilic or hebephiliac behavior emerging after testosterone replacement therapy (TRT) has never been described.</div></div><div><h3>Case presentation</h3><div>a patient diagnosed with Gordon-Holmes syndrome (GHS), a genetic condition characterized by cerebellar ataxia and hypogonadotropic hypogonadism (HH), at the age of 55 developed hebephiliac attitudes after starting TRT. A multidisciplinary approach integrating psychiatric evaluation, general (IQ) and specific (social cognition) neuropsychological assessment, and structural brain MRI was important to characterize the patient's clinical and functional profile.</div></div><div><h3>Discussion</h3><div>We discuss how the co-occurrence of HH, requiring hormone replacement therapy, combined with the patient's borderline IQ explains the sexual offenses against pre-adolescents in light of the Insufficient but Non-Redundant Parts of Unnecessary but Sufficient Conditions (INUS) model of causation. In other words, both the administration of TRT and the borderline IQ are configured as INUS causes for understanding the illegal behavior.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"3 2","pages":"Article 100237"},"PeriodicalIF":0.0,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142417631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esketamine-Induced acute transient psychotic episode in treatment-resistant depression: A case report 艾司他敏诱发耐药抑郁症患者急性一过性精神病发作：病例报告

Psychiatry research case reports Pub Date : 2024-09-20 DOI: 10.1016/j.psycr.2024.100236

Özgür Değirmenci , Ezgi Key , Defne Dakota , Ali Saffet Gonul

{"title":"Esketamine-Induced acute transient psychotic episode in treatment-resistant depression: A case report","authors":"Özgür Değirmenci , Ezgi Key , Defne Dakota , Ali Saffet Gonul","doi":"10.1016/j.psycr.2024.100236","DOIUrl":"10.1016/j.psycr.2024.100236","url":null,"abstract":"<div><div>The approval of intranasal esketamine offers a novel therapeutic avenue for managing treatment-resistant depression (TRD), albeit concerns regarding its potential side effects persist. We present a case of esketamine-induced acute transient psychotic episode in a 55-year-old male with TRD who had no history of psychosis or substance abuse. The patient had a long history of depression with relapses after initial response to antidepressants or ECT (Electroconvulsive Therapy). In the recent treatment, esketamine was added to ongoing treatment with venlafaxine 300 mg/day and olanzapine 10 mg/day. Forty-eight hours after esketamine administration, he exhibited acute psychotic symptoms requiring emergency intervention. Subsequent treatment adjustments and electroconvulsive therapy led to partial remission. This case underscores the potential risk of psychosis associated with esketamine and highlights the need for further research into its short- and long-term adverse effects. Factors such as patient history, monitoring protocols, and optimal treatment duration remain uncertain, emphasizing the importance of careful patient selection and monitoring when using esketamine for TRD management.</div></div>","PeriodicalId":74594,"journal":{"name":"Psychiatry research case reports","volume":"3 2","pages":"Article 100236"},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0