Expanding the role of metoclopramide in Tardive Dyskinesia: A case report

Psychiatry research case reports Pub Date : 2024-11-03 DOI:10.1016/j.psycr.2024.100238

Evaristus Chino Ezema , Ngozi Akueme , Precious Okpechi , Omotola Emmanuel , Omosumwen Ede , Sanmi Michael Obe , Ndukaku Ogbonna , Maureen Obi , Nnenna Bessie Emejuru , Ogochukwu Agazie , Vivien Obitulata Ugwu , John Mmaduabuchi , Emmanuel Chiebuka , Valentine Keke , Chinenye Loveth Aleke

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Abstract

Tardive dyskinesia is a medication-induced movement disorder commonly caused by the blockade or depletion of dopamine in the basal ganglia, seen mostly in the psychiatric setting following prolonged use of antipsychotic medications. It is also reported in other settings where patients receive non-antipsychotic medications. The prevalence of tardive dyskinesia varies across age, gender, and race, with women of middle age being more prone to develop tardive dyskinesia more than men. Therefore, we report a case of tardive dyskinesia, post-delivery, in an African woman, who received metoclopramide as part of premedication for spinal anesthesia for an emergency cesarean delivery. The debriefing period following the resolution of the symptoms offered a clue to prior utilization of metoclopramide for the treatment of hyperemesis gravidarum as provided by the patient's family. Hence, fulfilling the diagnostic criteria of prolong usage of the implicating agent.

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扩大甲氧氯普胺在迟发性运动障碍中的作用：病例报告

迟发性运动障碍是一种由药物引起的运动障碍，通常是由于基底神经节中的多巴胺被阻断或耗竭所致，多见于长期服用抗精神病药物后的精神病患者。在其他接受非抗精神病药物治疗的环境中也有报道。迟发性运动障碍的发病率因年龄、性别和种族而异，中年女性比男性更容易患上迟发性运动障碍。因此，我们报告了一例非洲裔产妇分娩后出现迟发性运动障碍的病例，该产妇在进行紧急剖宫产的脊髓麻醉前服用了甲氧氯普胺。症状缓解后的情况汇报提供了一条线索，即患者家属提供的甲氧氯普胺曾用于治疗妊娠剧吐。因此，符合长期使用相关药物的诊断标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Psychiatry research case reports Medicine and Dentistry (General)

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