Postepy psychiatrii neurologii最新文献

{"title":"Are children with attention-deficit/ hyperactivity disorder (ADHD) more likely to develop celiac disease? A prospective study.","authors":"Mohammad Hasan Mohammadi,&nbsp;Mehran Hesaraki","doi":"10.5114/ppn.2023.127573","DOIUrl":"https://doi.org/10.5114/ppn.2023.127573","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate whether the prevalence of celiac among attention-deficit/hyperactivity disorder (ADHD) patients is higher than among the normal population.</p><p><strong>Methods: </strong>The present study was a prospective one investigating ADHD children referred to the Neurology Clinic and Pediatric Ward at Amir Al-Momenin Hospital of Zabol (Sistan and Baluchestan, Iran) in 2019 after their parents' signing of a consent form. All patients underwent Biocard™ Celiac and serology tests. Data were analyzed with SPSS version 21 software.</p><p><strong>Results: </strong>Of all 76 ADHD children undergoing a serum IgA antibodies concentration test, 58 (76%) were male and 18 (23.7%) were female. The mean age of the children was 6.9 ± 2.4, ranging from 2 years to 12 years. The diagnosis of IgA immunodeficiency was rejected for all children based on total serum IgA antibody results. The overall mean anti-tissue transglutaminase (TTG) level was 6.8 ± 5.3 U/ml, ranging from 0.2 to 37 U/ml. There was no significant difference regarding TTG levels between boys and girls (5.1 vs. 6.0) U/ml. Based on the anti-TTG level results, no celiac case was found among the ADHD patients.</p><p><strong>Conclusions: </strong>There is as yet no evidence suggesting a link between celiac disease and ADHD. Thus, routine celiac disease screening when evaluating for ADHD (and is not recommended). However, the possibility of untreated celiac disease predisposing an individual to ADHD-like behaviors should be considered. Hence, physicians are recommended to evaluate a broad range of physical symptoms, in addition to typical neuropsychiatric symptoms, when evaluating ADHD patients.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 2","pages":"92-95"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/07/a4/PPN-32-50704.PMC10367511.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bruns syndrome in a patient with intraventricular subependymoma: a case report.","authors":"Piotr Iwanowski,&nbsp;Sławomir Michalak,&nbsp;Dominik Kobylarek,&nbsp;Bartosz Sokół,&nbsp;Amelia Ilnicka,&nbsp;Piotr Stajgis,&nbsp;Pitchaya Wanleenuwat,&nbsp;Nattakarn Limphaibool,&nbsp;Wojciech Kozubski","doi":"10.5114/ppn.2023.129338","DOIUrl":"https://doi.org/10.5114/ppn.2023.129338","url":null,"abstract":"<p><strong>Purpose: </strong>Subependymoma is a slow-growing benign brain neoplasm, classified by the World Health Organization (WHO) as a grade I tumor, which typically presents in middle-aged male adults.</p><p><strong>Case description: </strong>A case of Bruns syndrome and an intraventricular subependymoma in a 49-year-old patient who presented with intractable headache and vertigo is discussed in this paper. Imaging revealed a well-delimited cystic and solid mass near the lateral ventricle.</p><p><strong>Comment: </strong>Complete surgical excision of the tumor resulted in the restoration of normal cerebrospinal fluid pathway and resolution of clinical symptoms with no signs of tumor recurrence in the 4-year follow-up period.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 2","pages":"110-114"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b4/90/PPN-32-51054.PMC10367514.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10240998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Young's early maladaptive schemas versus psychopathic traits in a non-clinical population.","authors":"Magdalena Doroszczyk,&nbsp;Monika E Talarowska","doi":"10.5114/ppn.2023.128737","DOIUrl":"https://doi.org/10.5114/ppn.2023.128737","url":null,"abstract":"<p><strong>Purpose: </strong>There is now evidence that certain psychopathic personality components have their roots in a dysfunctional family of origin. Looking at this phenomenon from the perspective of Jeffrey E. Young's theory, we can surmise that the early negative experiences of people with psychopathic personality traits may have influenced the formation of specific maladaptive schemas. The purpose of this study is to examine the relationship between Young's early maladaptive schemas and psychopathic personality traits in a non-clinical population.</p><p><strong>Methods: </strong>The study involved 150 individuals aged 18 to 45. Eighty-six percent of the study group were women. The Psychopathic Personality Traits Scale - Revised (PPTS-R) and the Triarchic Psychopathy Measure (TriPM), designed to test the intensity of psychopathic traits in the study group, were used. Young's Schema Questionnaire (YSQ-S3-PL) was applied to measure Young's early maladaptive schemas.</p><p><strong>Results: </strong>Statistical analyses revealed significant positive correlations between the severity of psychopathy as measured by the TriPM and the following schemas: Emotional Deprivation, Mistrust/Abuse, Entitlement/Grandiosity, Insufficient Self-Control/Self-Discipline, and Approval Seeking/Recognition Seeking. For the PPTS-R scale, positive correlations were found for thirteen of the eighteen schemas. The strongest correlations across questionnaires were found for the Entitlement/Grandiosity schema. The domain of early maladaptive schemas most strongly associated with psychopathy was Impaired Limits.</p><p><strong>Conclusions: </strong>The Entitlement/Grandiosity, Insufficient Self-Control/Self-Discipline, Mistrust/Abuse, and Emotional Deprivation schemas are all associated with psychopathic personality traits. The strongest correlations are in the Entitlement/Grandiosity schema. The domain of early maladaptive schemas most strongly associated with psychopathy is the Impaired Limits domain.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 2","pages":"83-91"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/67/5a/PPN-32-50868.PMC10367516.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10241000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are YouTube videos a reliable source of information about body dysmorphic disorder?","authors":"Maria Dobosz,&nbsp;Miłosz Lewandowski,&nbsp;Zuzanna Świerczewska,&nbsp;Wioletta Barańska-Rybak,&nbsp;Wiesław J Cubała","doi":"10.5114/ppn.2023.128706","DOIUrl":"https://doi.org/10.5114/ppn.2023.128706","url":null,"abstract":"<p><strong>Purpose: </strong>Body dysmorphic disorder (BDD) is characterized by a preoccupation with a non-existing or minimal defect in appearance. It affects around 2% of the population, causes distress in daily functioning and reduces the quality of life. The aim of this study was to evaluate the usefulness and the quality of the most viewed videos regarding BDD on YouTube.</p><p><strong>Methods: </strong>YouTube was searched for the keywords \"body dysmorphia\" and \"dysmorphophobia\". The validated DISCERN instrument and the Global Quality Score (GQS) were used to assess video quality. The Video Power Index (VPI) score was used to evaluate the popularity of videos.</p><p><strong>Results: </strong>Only 3 videos were rated as good quality based on the DISCERN criteria. The mean DISCERN score between the raters was 32.89 ± 9.23, while the mean GCQ score was 2.84 ± 1.03. Even though only 23.7% of the videos were uploaded by a healthcare source, there was a significant difference between DISCERN scores depending on the source of the video: healthcare - 42 mean vs. non-healthcare - 30.07 mean (<i>p</i> = 0.0035). The mean score for the VPI was 2757 (range, 244.57-11,647.12).</p><p><strong>Conclusions: </strong>Our study showed that the quality of BDD-related videos on YouTube is poor. Physicians or healthcare organizations should publish more medical content on YouTube, increasing the amount of more reliable and better-quality content for patients.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 2","pages":"76-82"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3e/c8/PPN-32-50860.PMC10367510.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10240999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body mass index and sleep disturbances: a systematic review and meta-analysis.","authors":"Sohrab Amiri","doi":"10.5114/ppn.2023.129067","DOIUrl":"https://doi.org/10.5114/ppn.2023.129067","url":null,"abstract":"<p><strong>Purpose: </strong>Overweight and obesity have been common non-communicable diseases in recent years that have far-reaching health effects. This study aimed to study the risk of sleep disturbances based on overweight and obesity using a systematic review and meta-analysis.</p><p><strong>Views: </strong>Three sources of scientific information, namely PubMed, Scopus, and Embase, were selected as scientific databases and searched for articles published in English until May 2021. Also, a manual search on related articles was done. The resulting data required a meta-analysis based on odds ratios, which were extracted and then pooled. The odds ratio was calculated based on the random-effects method. Publication bias and the degree of heterogeneity were studied. Twenty-one longitudinal studies were selected for this meta-analysis. The odds ratio (OR) in this association between body mass index (BMI) ≥ 25 and sleep disturbances was 1.33 and the confidence interval (CI) was between 1.16-1.51. This OR was 1.12 and CI was between 0.98-1.29 in overweight. The OR was 1.24 and CI was between 1.07-1.44 in obesity. The OR was 1.92 and CI was between 0.89-4.15 in men. The OR was 1.47 and CI was between 1.15-1.89 in women. Publication bias and heterogeneity were evident in the meta-analysis.</p><p><strong>Conclusions: </strong>Obesity increases the risk of sleep disturbances in the long term, and both obesity and sleep disturbances have negative effects on health, so it is necessary to develop appropriate interventions to improve obesity.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 2","pages":"96-109"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/be/PPN-32-50959.PMC10367528.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional assessment and evaluation of health problems with the cervical spine among dental assistants and hygienists.","authors":"Radosław Janczyk,&nbsp;Małgorzata Janczyk,&nbsp;Marcin Sibiński,&nbsp;Marek Drobniewski","doi":"10.5114/ppn.2023.129053","DOIUrl":"https://doi.org/10.5114/ppn.2023.129053","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to evaluate the mobility of the cervical spine, pain and function according to Neck Disability Index (NDI) scores among dental assistants and hygienists. Comparison between dental professionals and a control group was also performed.</p><p><strong>Methods: </strong>In the study, 338 dental assistants and hygienists with a mean age of 35.8 were evaluated. Of these, 195 were measured with the CROM 3 device, and 143 with a classic tape measure, for the range of motion of their cervical spine. A non-dental professional group consisting of 60 women (whose work was not related to repetitive movements of cervical spine) was also tested, 30 with the CROM 3 device, and 30 with a classic tape measure. The dental and control groups were also surveyed with the NDI questionnaire and Visual Analogue Scale (VAS).</p><p><strong>Results: </strong>Dental assistants and hygienists had significantly reduced functional ROM in all directions in comparison to the control group. Among the 338 volunteers form the study group the VAS pain score was higher than in the control group. NDI scores were also worse in the study group, compared to the control group. Functional results in all subgroups of the NDI questionnaire were better in the control group. Among dental workers the cervical spine typically demonstrated significantly greater mobility in right-rotation, resulting from the position occupied at the unit at which they work.</p><p><strong>Conclusions: </strong>Our findings confirm a decrease in the mobility of the cervical spine, lower functional scores involving various everyday activities and greater intensity of pain among dental assistants and hygienists in comparison to participants whose work does not involve cervical spine overuse.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 2","pages":"68-75"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/63/ae/PPN-32-50953.PMC10367507.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of various diet patterns among patients with multiple sclerosis.","authors":"Magdalena Zielińska, Izabela Michońska","doi":"10.5114/ppn.2023.127246","DOIUrl":"10.5114/ppn.2023.127246","url":null,"abstract":"<p><strong>Purpose: </strong>The main aim of the study was to compare the effectiveness of the dietary patterns studied in the context of multiple sclerosis (MS), including anti-inflammatory, Mediterranean diet (MD), Mediterranean-DASH intervention for neurodegenerative delay (MIND), intermittent fasting (IF), gluten-free and ketogenic diets. In addition, another aim was to verify or otherwise the efficacy of other alternative dietary models, which include the Paleo diet, the Wahls diet, the McDougall diet and the Swank diet. Whether and to what extent the use of different dietary regimens can affect the course and reduction of individual MS symptoms was also examined. The advantages and disadvantages of selected diets and dietary patterns in the context of MS are discussed.</p><p><strong>Views: </strong>Autoimmune diseases are estimated to affect more than 3% of the world's people, the majority of whom are of working age. Therefore, delaying the first manifestation of the disease, reducing the number of relapses and alleviating symptoms are particularly welcome developments. In addition to finding effective pharmacotherapy, high hopes for patients lie in nutritional prevention and diet therapy. For years the medical literature has discussed supporting the treatment of diseases caused by an impairment of the body's immune system with the help of nutrition.</p><p><strong>Conclusions: </strong>An appropriate and balanced diet can be extremely helpful in improving the condition and well-being of patients with MS, and effectively support drug therapy.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 1","pages":"49-58"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/96/PPN-32-50653.PMC10243296.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9652984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between occupational burnout and work ability among firefighters: exploring the mediating effects of insomnia, depressive symptoms, loneliness and alcohol misuse.","authors":"Bogdan Stefanowski,&nbsp;Łukasz Mokros,&nbsp;Halina Sienkiewicz-Jarosz,&nbsp;Łukasz Baka,&nbsp;Joanna Bugajska,&nbsp;Piotr Świtaj","doi":"10.5114/ppn.2023.127181","DOIUrl":"https://doi.org/10.5114/ppn.2023.127181","url":null,"abstract":"<p><strong>Purpose: </strong>Firefighting is a profession associated with a high risk of elevated levels of occupational stress and burnout. The aim of this cross-sectional study was to explore the mediating effects of insomnia, depressive symptoms, loneliness and alcohol misuse in the relationship between two dimensions of burnout (i.e., exhaustion and disengagement) and work ability among firefighters.</p><p><strong>Methods: </strong>A total of 460 firefighters from various regions of Poland completed a set of self-report questionnaires to assess constructs of interest. A mediation model was constructed to verify hypothesized paths, adjusted for socio-demographic and work-related background characteristics. Model parameters were estimated using a bootstrapping procedure, with sampling set at <i>N</i> = 1000.</p><p><strong>Results: </strong>The proposed model explained 44% of variance in work ability. Higher levels of both exhaustion and disengagement predicted worsened work ability. When mediators were controlled for, these effects remained statistically significant. Depressive symptoms and feelings of loneliness were found to be partial mediators of the association between exhaustion and work ability, and between disengagement and work ability. The mediating effects of insomnia and alcohol misuse were non-significant.</p><p><strong>Conclusions: </strong>Interventions aimed at counteracting the decrement in work ability among firefighters should target not only occupational burnout, but also depressive symptoms and a sense of loneliness as factors mediating its detrimental effects.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/d9/PPN-32-50630.PMC10243294.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9600060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family history of stroke - a useful clue for the primary care physician and stroke neurologist: a narrative review.","authors":"Michał Błaż,&nbsp;Iwona Sarzyńska-Długosz","doi":"10.5114/ppn.2023.126482","DOIUrl":"https://doi.org/10.5114/ppn.2023.126482","url":null,"abstract":"<p><strong>Purpose: </strong>The heritability of ischemic stroke is a complex mechanism, involving the contribution of genetic traits and environmental factors, which is why in everyday practice clinicians often rely on the broad term \"family history of stroke\", defined as the case of any first-degree relative who has had a stroke. The aim of this review is to update the available data regarding family history of stroke in primary and secondary stroke prevention by searching the electronic Scopus database for the phrase TITLE-ABS-KEY (\"family history\" AND \"stroke\").</p><p><strong>Views: </strong>A total of 140 articles met the pre-specified criteria and were included in the review. The prevalence of family history of stroke ranged from 37% in stroke-free individuals to 52% in patients with ischemic stroke. In primary prevention, family history of stroke was associated with increased risk of stroke, transient ischemic attack, stroke risk factors and stroke-like symptoms. In patients with ischemic stroke, it was more often associated with small- and large-vessel disease, though not with a cardioembolic etiology. Family history of stroke did not influence long-term functional outcomes after rehabilitation. In young stroke victims, it was related to symptom severity and the risk of a second stroke.</p><p><strong>Conclusions: </strong>Consideration of family history of stroke in everyday practice may carry useful information both for primary care physicians and stroke neurologists.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 1","pages":"31-39"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/61/PPN-32-50514.PMC10243297.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9603150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bruton's tyrosine kinase inhibitors in the treatment of multiple sclerosis.","authors":"Olga Shulga,&nbsp;Anna Chabanova,&nbsp;Oleksandra Kotsiuba","doi":"10.5114/ppn.2023.126319","DOIUrl":"https://doi.org/10.5114/ppn.2023.126319","url":null,"abstract":"<p><strong>Purpose: </strong>In this review, we have highlighted a new class of drugs, Bruton's tyrosine kinase (BTK) inhibitors, and summarized the results of recent clinical trials in the treatment of multiple sclerosis.</p><p><strong>Views: </strong>Multiple sclerosis (MS) is considered an autoimmune disease of the central nervous system, in which B-lymphocytes and myeloid cells, such as macrophages and microglia, play an important role in the pathogenesis. B-cells induce pathological processes by presenting autoantigens to T-lymphocytes, secreting pro-inflammatory cytokines, and forming ectopic lymphoid follicle-shaped clusters. Accordingly, the activation of microglia contributes to the development of chronic inflammation due to the production of chemokines, cytokines, reactive oxygen, and nitrogen species. BTK is an enzyme important in the activation and function of both B-lymphocytes and microglia. The demand for highly effective and well-tolerated drugs still remains at all stages of MS despite the availability of a number of effective drugs against the disease. Thus, in recent years BTK inhibitors have been the newest approach in the treatment of MS, since they affect the leading links of the pathogenesis of this disease and are able to pass through the blood-brain barrier.</p><p><strong>Conclusions: </strong>The study of new mechanisms of the development of MS continues in combination with the elaboration of new treatment methods, i.e., Bruton's tyrosine kinase inhibitors. The review provided the analysis of core studies evaluating the safety and efficacy of these drugs. In the future, positive results of these studies will be able to greatly expand the therapy for various forms of MS.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"32 1","pages":"23-30"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/22/PPN-32-50480.PMC10243295.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9600059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}