Postepy psychiatrii neurologii最新文献

{"title":"Transient shortening of activated partial thromboplastin time and prothrombin time associated with transient global amnesia.","authors":"Dariusz Dziubek, Karolina Dziubek, Marcelina Stodolak","doi":"10.5114/ppn.2025.149970","DOIUrl":"https://doi.org/10.5114/ppn.2025.149970","url":null,"abstract":"<p><strong>Purpose: </strong>Transient global amnesia (TGA) manifests as acute short-term memory disturbances lasting up to 24 hours. The pathophysiology of the disease remains unclear. This paper presents the case of a patient with recurrent TGA, in whom a shortening of coagulation times and high blood pressure peaks were observed during each acute phase of the disease, suggesting transient increased blood coagulability and transient dysregulation of autonomic blood pressure control.</p><p><strong>Case description: </strong>A 59-year-old patient with medical history of migraine and arterial hypertension was diagnosed with recurrent TGA (two episodes within a year). Each time, upon admission to hospital, high blood pressure peaks were recorded and activated partial thromboplastin time (aPTT) and prothrombin time (PT) were shortened with gradual normalization over the following days.</p><p><strong>Comment: </strong>The shortening of aPTT and PT may suggest a relationship between TGA and transient blood coagulation disorders in the acute phase.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"34 1","pages":"54-57"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The real-life reliability of the modified Rankin scale used in a stroke unit and a rehabilitation ward.","authors":"Natalia A Pożarowszczyk, Iwona Kurkowska-Jastrzębska, Iwona M Sarzyńska-Długosz, Maciej Nowak, Michał Karliński","doi":"10.5114/ppn.2025.149879","DOIUrl":"10.5114/ppn.2025.149879","url":null,"abstract":"<p><strong>Purpose: </strong>The modified Rankin scale (mRS) is the gold standard for measuring stroke-related disability in clinical trials and everyday practice. However, inter-observer variability is a source of bias that may undermine the reliability of retrospective studies. It may also depend on clinical backgrounds of different assessing physician. Our aim was to prospectively assess real-life consistency between stroke unit physicians (SUPs) and physical and rehabilitation medicine physicians (PRMPs) using mRS in patients transferred directly from a stroke unit (SU) to a rehabilitation ward (RW).</p><p><strong>Methods: </strong>We enrolled 48 consented stroke patients transferred within the same hospital from SU to RW. Patients were scored in mRS by a SUP and a PRMP at the day of transfer as a standard of care. The reference mRS score (REF) was obtained by a single- blinded stroke physician using the Rankin Focused Assessment form to guide an interview.</p><p><strong>Results: </strong>An mRS score was reported for all patients admitted to the RW and 33 patients discharged from the SU. The overall agreement was 75.8% between the assessments of SUPs and PRMPs (κ = 0.58), 72.7% between SUPs and the REF (κ = 0.55) and 70.0% between PRMPs and the REF (κ = 0.49). A similar agreement was observed for PRMPs and the REF in the sensitivity cohort of 48 patients (66.7%; κ = 0.46). Patients with the REF mRS of 2 (<i>n</i> = 6) were often scored as 3 both by SUPs (4/6) and PRMPs (5/6). In patients with the REF mRS of 3 or 4 there was no clear tendency towards overrating disability.</p><p><strong>Conclusions: </strong>The reliability of mRS scoring in everyday practice is modest and does not seem to depend on clinical background of assessing physician.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"34 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravenous tissue plasminogen activator in functional stroke mimics.","authors":"Magdalena M Kowalska, Małgorzata M Michałowska, Marta M Leńska-Mieciek","doi":"10.5114/ppn.2025.149942","DOIUrl":"https://doi.org/10.5114/ppn.2025.149942","url":null,"abstract":"<p><strong>Purpose: </strong>Time pressure in the treatment of acute ischemic stroke patients generates difficult decisions for neurologists, sometimes resulting in stroke mimic patients receiving intravenous thrombolytic therapy. Proper diagnosis and appropriate treatment for these patients are crucial, yet incredibly challenging in cases of functional stroke mimics (FSM).</p><p><strong>Views: </strong>Functional neurological disorders, including FSM, are increasingly diagnosed. However, their pathophysiology and underlying mechanisms are poorly understood, even though the diagnostic criteria for diagnosing FSM exist, and various clinical indicators support them. Functional neurological symptoms often result in serious disability for patients but the effective treatment is unknown. Neurologists need to examine the symptoms and the key clinical findings to distinguish between FSM and stroke. The intravenous thrombolytic therapy appears safe for FSM, but the potential harm of thrombolysis should be a concern. FSMdiagnosed patients require long-term treatment, starting with open and clear communication about their condition and followed by psychoeducation and physiotherapy.</p><p><strong>Conclusions: </strong>FSM should be diagnosed using the diagnostic criteria. Electronic health information exchange among healthcare providers is necessary to avoid unnecessary thrombolytic treatments in this group of patients.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"34 1","pages":"33-43"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mommy, am I good? Case report of a 12-year-old boy with abused child syndrome.","authors":"Oliwia Froń, Rafał Szmajda, Aleksandra Lewandowska","doi":"10.5114/ppn.2024.147367","DOIUrl":"10.5114/ppn.2024.147367","url":null,"abstract":"<p><strong>Purpose: </strong>Abused child syndrome remains a significant public health concern with profound physical and psychological implications.</p><p><strong>Case description: </strong>We present a case report of a 12-year-old child who was admitted to the child inpatient psychiatric unit of a paediatric hospital with signs and symptoms of abuse. The child was malnourished but did not exhibit physical injuries. A detailed medical history revealed inconsistent explanations regarding the diets used by the mother, allegedly recommended by a neurologist. Diagnostic evaluation, including medical examination, laboratory tests, and imaging studies supported the suspicion of child maltreatment. The case was reported to the police and the court. Appropriate interventions were initiated, including treatment, social work involvement, and psychosocial support.</p><p><strong>Comment: </strong>This case highlights the importance of early recognition, comprehensive assessment, and multidisciplinary cooperation in addressing child abuse. Medical professionals play a critical role in child safety and should be vigilant in identifying and reporting suspected cases of child abuse and neglect. How they respond and whether they notify the justice authorities may determine the child's future fate and even his or her life.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"267-271"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacotherapy and psychotherapy in depression - complementarity or exclusion?","authors":"Anna Mosiołek, Marlena Podlecka","doi":"10.5114/ppn.2024.147104","DOIUrl":"10.5114/ppn.2024.147104","url":null,"abstract":"<p><strong>Purpose: </strong>This article attempts to outline the dilemma regarding the use of pharmacotherapy and psychotherapy in the treatment of mental disorders with particular emphasis on depression. Depressive disorder is one of the most common mental disorders suffered by society; it affects from 5% to over 12% of the population [1]. It is also a growing problem as the number of diagnoses has increased over the last decades.</p><p><strong>Views: </strong>The numerous organisations working to improve mental health have constructed guidelines focused on shaping preventive intervention and therapeutic procedures. However, the method of selecting a procedure remains unclear, with the choice between pharmacotherapy and psychotherapy being particularly troublesome. This begs the question of whether these forms of interaction are complementary or exclusive. The article provides an overview of the current discussion on the legitimacy of using multiple forms of interactions when treating depression. Currently, the treatment of depression is based primarily on pharmacotherapy using antidepressants and psychotherapy as well as combined treatment.</p><p><strong>Conclusions: </strong>Although a diverse range of psychotherapeutic approaches are used to treat depression, research indicates that all leading approaches are similarly effective. Pharmacotherapy and psychotherapy offer comparable effectiveness in reducing depressive symptoms and demonstrate similar effects on neuronal activity. Combined treatment may offer optimal effectiveness, especially with moderate and severe symptoms of depression.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"257-266"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of fatty acids in the emotional well-being of young adults: associations between fatty acid levels and symptoms of depression, anxiety, stress, and sleep disturbances.","authors":"Hanna Karakuła-Juchnowicz, Agnieszka Banaszek, Ryszard Sitarz, Kaja Karakuła, Zuzanna Wingralek, Zuzanna Rząd, Ewa Stachowska, Natalia Jakubiak, Ewa Urbańska, Dariusz Juchnowicz, Joanna Rog","doi":"10.5114/ppn.2024.144224","DOIUrl":"10.5114/ppn.2024.144224","url":null,"abstract":"<p><strong>Purpose: </strong>Young adults experience high stress levels, leading to mood disorders. This study investigates the associations between specific fatty acid levels, lipid profiles, inflammatory markers, and emotional well-being among young adults.</p><p><strong>Methods: </strong>Seventy-two young adults aged 18-35 participated in this study. Participants completed self-assessments of depression severity (PHQ-9), stress (PSS-10), insomnia (ISI), and anxiety (GAD-7). Blood samples were collected and analyzed for plasma fatty acid profiles, lipid profiles, C-reactive protein (CRP) and kynurenine pathway metabolites. Classification and Regression Tree (C&RT) and multivariate stepwise regression analyses were employed to identify potential predictors of mental health outcomes.</p><p><strong>Results: </strong>The analyses revealed significant associations between certain fatty acids, lipid markers, and mental health conditions. Lauric acid, myristic acid, and eicosatrienoic acid were identified as potential indicators of mental health issues. Higher levels of palmitoleic acid were linked to increased depressive symptoms, while higher oleic acid levels were associated with reduced depression. Anxiety was influenced by myristoleic acid and docosahexaenoic acid. Stress and sleep disturbances correlated with specific fatty acids. The models explained a significant percentage of variability in mental health outcomes, accounting for 25% in both depressive symptoms and anxiety, 23% in stress, and 43% in sleep disturbances.</p><p><strong>Conclusions: </strong>Specific fatty acids, associated with lipid profiles, kynurenic acid, and CRP, significantly impact the mental health of young adults. Monitoring biomarkers may assist in managing mental health disorders. Personalized dietary interventions could improve well-being and sleep quality. Further research is needed to confirm these findings and establish causal relationships.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"201-212"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manual therapy compared to surgery in the treatment of moderate carpal tunnel syndrome.","authors":"Przemysław T Wielemborek, Katarzyna Kapica-Topczewska, Marek Bielecki, Rafał Kułakowski, Dagmara Mirowska-Guzel, Jan Kochanowicz, Alina Kułakowska","doi":"10.5114/ppn.2024.147102","DOIUrl":"10.5114/ppn.2024.147102","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to assess the efficacy of manual therapy, specifically using the Maitland concept, in treating carpal tunnel syndrome (CTS), and to compare its effectiveness with surgical decompression of the median nerve.</p><p><strong>Methods: </strong>A total of 69 patients were enrolled and divided into two groups: a control group (undergoing surgery) and treatment group (receiving manual therapy). Subgroups were formed based on gender, considering factors such as grip strength. Inclusion criteria comprised active symptoms of CTS and electrophysiological evidence of nerve lesion. Exclusion criteria included diabetes, thyroid diseases, trauma to the upper limb, and pregnancy. Baseline and 10-12 month post-intervention assessments encompassed EQ-5D-5L, CTS6, DASH, grip strength and electrophysiological studies. The treatment group (43 patients) underwent five weekly manual therapy sessions. A physiotherapist individually assessed and treated patients, emphasizing passive techniques and prescribing home self-neuromobilization. The control group (26 patients) underwent carpal tunnel release surgery.</p><p><strong>Results: </strong>Both surgical and manual therapy interventions significantly reduced symptom severity (<i>p</i> < 0.001). Manual therapy improved hand function in females (<i>p</i> < 0.001) and showed positive trends in the control group. The treatment group demonstrated higher grip strength, with significant improvements in females (<i>p</i> < 0.001). Quality of life also improved in females (<i>p</i> < 0.001). No significant differences in distal motor latency though sensory latency showed positive trends in females.</p><p><strong>Conclusions: </strong>This research offers a comprehensive understanding of the effectiveness of manual therapy and surgical release in treating CTS. The findings suggest that both interventions can result in improvements in grip strength and quality of life with variations in based on gender and specific outcome measures.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"248-256"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MoodMon: novel optimization of bipolar disorder monitoring through patient-driven voice parameter submission and AI technology.","authors":"Marlena Sokół-Szawłowska, Olga Kamińska, Małgorzata Sochacka","doi":"10.5114/ppn.2024.147100","DOIUrl":"10.5114/ppn.2024.147100","url":null,"abstract":"<p><strong>Purpose: </strong>Behavioral data collected from smartphones can assist artificial intelligence (AI) in assessing and predicting fluctuations in mental states in patients with bipolar disorder (BD). In Poland, the MoodMon online system is used to integrate passive and active data, including voice parameters, for analysis and the issue of alerts based on changes in individual's mental state. The study aims to explore whether active engagement of the patient enhances the efficacy of the advanced MoodMon tool. This clinical trial is embedded in a broader research initiative.</p><p><strong>Methods: </strong>Methodologically, smartphones were used to automatically collect daily activity data from wristbands and phones of 75 BD patients. Clinical evaluations, using the Hamilton Depression and Young Mania Rating Scales were conducted via a web app, regular visits, calls, or system-initiated contacts after alerts. The MoodMon system, trained on patient data, was compared against clinical evaluations, successfully predicting mental states.</p><p><strong>Results: </strong>Results showed high alert accuracy: true positive ratio (TPR) at 86.6% (sensitivity) and true negative ratio (TNR) at 98.59% (specificity). Active patient voice data submissions notably improved the prediction of changes or stability in mental states.</p><p><strong>Conclusions: </strong>Active patient participation in data submission enhances MoodMon's effectiveness as an AI-driven monitoring tool for BD. This underscores the potential of behavioral markers and mobile health applications in mental health care.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"230-240"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous flexibility, attentional set shifting and cognitive control in men with alcohol dependence.","authors":"Ewa Zawadzka, Łucja Domańska","doi":"10.5114/ppn.2024.147099","DOIUrl":"10.5114/ppn.2024.147099","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to assess spontaneous flexibility, attentional set shifting and cognitive control in alcohol- dependent men in the process of therapy in alcohol addiction treatment units, and to recognise the use of production strategies in visual-spatial mode in this clinical group.</p><p><strong>Methods: </strong>A total of 72 men participated in the study, 43 were alcohol-dependent (ADS) and 29 were controls (CTR). The Ruff Figural Fluency Test (RFFT), the Color Trails Test part 2 (CTT-2) and the Montreal Cognitive Assessment (MoCA) were administered.</p><p><strong>Results: </strong>The findings showed that alcohol dependence significantly impacted performance CTT-2 and RFFT, beyond and above age and education. The ADS group performed significantly worse than controls in CTT-2 and all indices of RFFT. A significant interaction effect was observed between group and task type for perseverations, with ADS patients producing fewer perseverations for the first part of RFFT compared to other parts of the test. They also used fewer production strategies than controls.</p><p><strong>Conclusions: </strong>Our findings highlight that alcohol dependence specifically contributes to explaining the results in terms of reactive flexibility in the aspect of attentional set shifting, as well as spontaneous flexibility in tasks requiring the generation of unique designs in limited time. The alcohol-dependent group demonstrated poor cognitive control, as evidenced by significantly higher number of perseverations. Furthermore, an analysis of the production strategies employed by alcohol-dependent men provided important information about their control and planning capacities. These findings support the recommendation to work with cognitive stimulation in therapeutic work with this population.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"222-229"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Affective neuroscience correlates of personality and the formation of early maladaptive schemas - preliminary reports.","authors":"Monika E Talarowska, Małgorzata Juraś-Darowny","doi":"10.5114/ppn.2024.147098","DOIUrl":"10.5114/ppn.2024.147098","url":null,"abstract":"<p><strong>Purpose: </strong>The concept of emotional needs occupies a key place in Young's theory of early maladaptive schemas (EMS). The primary caregiver's attitude that is ineffective from the point of view of such needs leads to frustration, which is expressed in the personality of the child and in the resulting disorders. The purpose of this paper is to examine the relationship between retrospective evaluation of parenting as a tool for meeting basic emotional needs and the neural correlates of personality - affective neuroscience emotional systems, according to the theory by Panksepp.</p><p><strong>Methods: </strong>The study involved 65 individuals between the age of 18 and 62 years (mean age: <i>M</i> = 34.09). The following instruments were used: Young Parenting Inventory (YPI) and Affective Neuroscience Personality Scales (ANPS).</p><p><strong>Results: </strong>Meaningful statistical differences in mothers' and fathers' behavior are related to one domain - Impaired Autonomy and/or Performance (<i>p</i> < 0.001). Within this domain, all schemas reached statistical significance, with fathers showing the strongest influence on the formation of the Failure schema (<i>p</i> = 0.022). Across all schema, the majority of statistically significant results were found in two domains: Disconnection/Rejection and the Impaired Autonomy and/or Performance. Significant statistical correlations between EMS and neural emotional systems were predominantly associated with the Anger and Sadness systems.</p><p><strong>Conclusions: </strong>Retrospective assessments of maternal and paternal behaviors show the strongest associations with schemas in two EMS domains: Disconnection/Rejection and Impaired Autonomy/Performance. These two domains are further linked to the activation of two neural emotional systems: Anger and Sadness.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 1","pages":"213-221"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}