Asieh Mehramiri, Mehrsa Heidari, Mohammad Bahadoram, Esma'il Akade
{"title":"Severe headache as the first presentation of post-COVID-19 brain and spinal cord injury resembling neurosarcoidosis.","authors":"Asieh Mehramiri, Mehrsa Heidari, Mohammad Bahadoram, Esma'il Akade","doi":"10.5114/ppn.2024.144608","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Sarcoidosis, a multi-organ granulomatous disease, occasionally involves the nervous system, presenting as neurosarcoidosis. The following case demonstrates a potential association between COVID-19 and brain and spinal cord injury mimicking neurosarcoidosis.</p><p><strong>Case description: </strong>A 51-year-old woman presented with persistent holocranial headache, nausea, vertigo, and neurological deficits one month after a COVID-19 hospitalization. Neurological examination revealed hemiparesis, dysphagia, and ataxia. Imaging showed lesions in the central nervous system. A diagnosis of neurosarcoidosis was considered, supported by clinical criteria, imaging findings, and elevated ACE levels. Steroid therapy led to symptom improvement.</p><p><strong>Comment: </strong>This case underscores the broad range of the consequences of COVID-19 and challenges in diagnosing neurosarcoidosis, suggesting the need for further research in this area.</p>","PeriodicalId":74481,"journal":{"name":"Postepy psychiatrii neurologii","volume":"33 3","pages":"196-200"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11635430/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Postepy psychiatrii neurologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/ppn.2024.144608","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/5 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Purpose: Sarcoidosis, a multi-organ granulomatous disease, occasionally involves the nervous system, presenting as neurosarcoidosis. The following case demonstrates a potential association between COVID-19 and brain and spinal cord injury mimicking neurosarcoidosis.
Case description: A 51-year-old woman presented with persistent holocranial headache, nausea, vertigo, and neurological deficits one month after a COVID-19 hospitalization. Neurological examination revealed hemiparesis, dysphagia, and ataxia. Imaging showed lesions in the central nervous system. A diagnosis of neurosarcoidosis was considered, supported by clinical criteria, imaging findings, and elevated ACE levels. Steroid therapy led to symptom improvement.
Comment: This case underscores the broad range of the consequences of COVID-19 and challenges in diagnosing neurosarcoidosis, suggesting the need for further research in this area.
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