Parasites, hosts and diseases最新文献_第2页

Genotyping of Blastocystis species in hemodialysis patients from Makkah, Saudi Arabia. 沙特阿拉伯麦加血液透析患者囊虫种类基因分型研究。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-19 DOI: 10.3347/PHD.25052

Hattan S Gattan, Ebtihal O Bahwaireth, Majed H Wakid, Muslimah N Alsulami, Mohammed A Al-Matary, Asmaa M El-Kady

{"title":"Genotyping of Blastocystis species in hemodialysis patients from Makkah, Saudi Arabia.","authors":"Hattan S Gattan, Ebtihal O Bahwaireth, Majed H Wakid, Muslimah N Alsulami, Mohammed A Al-Matary, Asmaa M El-Kady","doi":"10.3347/PHD.25052","DOIUrl":"10.3347/PHD.25052","url":null,"abstract":"The human gut is host to a diversity of microorganisms, including a parasite called Blastocystis. While there are increasing reports characterizing Blastocystis subtypes (STs) among healthy individuals, only a few studies have investigated the Blastocystis STs in renal or dialysis patients. This study investigates the Blastocystis prevalence and STs in hemodialysis patients. Fifty healthy controls and 100 chronic kidney disease patients undergoing dialysis participated in the study. Blastocystis infection was identified by using microscopic and molecular diagnosis using 18S rRNA-PCR. Then all positive samples were sent for sequencing to identify which ST they belong to. Phylogenetic and pairwise distance analyses were performed to confirm the validity of the STs. Thirty-four hemodialysis patients were infected with Blastocystis while 17 patients in the control were infected with the parasite. All positive samples were then confirmed using PCR. Genetic sequencing analysis subsequently revealed that 66% of Blastocystis infection belonged to ST1 and ST3 (33% each), followed by ST10 (20%), and ST6 (14%). The nucleotide sequence analysis of the 385 bp 18S rRNA gene revealed a >97% identity with previously identified Blastocystis isolates. The genetic analysis showed that the 8 identified isolates correspond to previously observed alleles. Six ST1 isolates produced a high frequency of Blastocystis isolates matching allele 4, with very low genetic divergence. ST3 isolates showed relatively increased genetic diversity and matching allele 34, which is the most common allele worldwide.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":" ","pages":"62-69"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and validation of a species-specific loop-mediated isothermal amplification assay for rapid detection of Perkinsus marinus. 一种种特异性环介导的等温扩增快速检测方法的建立和验证。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-26 DOI: 10.3347/PHD.25083

S D N K Bathige, Seung-Hyeon Kim, Donghyun Lee, Hyung-Bae Jeon, Yu Chen, Kyung-Il Park

{"title":"Development and validation of a species-specific loop-mediated isothermal amplification assay for rapid detection of Perkinsus marinus.","authors":"S D N K Bathige, Seung-Hyeon Kim, Donghyun Lee, Hyung-Bae Jeon, Yu Chen, Kyung-Il Park","doi":"10.3347/PHD.25083","DOIUrl":"10.3347/PHD.25083","url":null,"abstract":"Perkinsus marinus is a major protozoan pathogen of oysters, responsible for severe mortality events and substantial economic losses in the global aquaculture industry. Rapid, sensitive, and reliable detection of this parasite is therefore essential for effective monitoring and timely control of dermo disease outbreaks. In this study, we developed and optimized a novel loop-mediated isothermal amplification (LAMP) assay, designated Pm-LAMP, for the specific detection of P. marinus in oyster tissues. The optimized Pm-LAMP assay, employing 5 primers and performed at 67°C, demonstrated high analytical sensitivity, consistently detecting DNA concentrations as low as 40 fg/µl and enabling accurate quantification down to 0.4 pg/µl. The assay exhibited linear amplification across a wide template range from 4 ng/µl to 0.4 pg/µl, with a strong inverse correlation between template concentration and threshold time. Specificity testing confirmed exclusive amplification of P. marinus, with no cross-reactivity observed for P. olseni, P. honshuensis, or P. chesapeaki. This study represents the first LAMP assay specifically designed for the detection of P. marinus. The Pm-LAMP assay was validated using Pacific oyster tissues and cultured P. marinus isolates originating from the USA and Korea and was benchmarked against quantitative real-time PCR (qPCR). Although qPCR exhibited higher sensitivity for detecting trace DNA levels, the Pm-LAMP assay produced results within 20 min while maintaining reliable detection at low DNA concentrations. Diagnostic performance evaluation showed 100% sensitivity and 90.91% specificity, with substantial agreement with qPCR (Cohen's κ=0.811). Overall, the Pm-LAMP assay provides a rapid, robust, and field-deployable diagnostic tool for P. marinus, supporting improved disease surveillance and sustainable oyster aquaculture management.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":" ","pages":"70-81"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12902072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146047472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic polymorphisms of merozoite surface protein-1 ICB 5-6 in Vietnamese Plasmodium vivax isolates. 越南间日疟原虫分离株卵裂子表面蛋白-1 icb5 -6的遗传多态性

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-14 DOI: 10.3347/PHD.25087

Thu Hằng Nguyễn, Đăng Thùy Dương Nguyễn, Hương Giang Lê, Tuấn Cường Võ, Nguyen Thi Minh Trinh, Minkyoung Cho, Chau Van Khanh, Huynh Hong Quang, Byoung-Kuk Na

{"title":"Genetic polymorphisms of merozoite surface protein-1 ICB 5-6 in Vietnamese Plasmodium vivax isolates.","authors":"Thu Hằng Nguyễn, Đăng Thùy Dương Nguyễn, Hương Giang Lê, Tuấn Cường Võ, Nguyen Thi Minh Trinh, Minkyoung Cho, Chau Van Khanh, Huynh Hong Quang, Byoung-Kuk Na","doi":"10.3347/PHD.25087","DOIUrl":"10.3347/PHD.25087","url":null,"abstract":"Plasmodium vivax merozoite surface protein-1 (PvMSP-1) is one of the major polymorphic markers for molecular epidemiological purposes. In particular, the interspecies conserved block 5-6 (ICB 5-6) of PvMSP-1 is a region exhibiting extensive genetic polymorphism. In this study, we analyzed polymorphic characters of the pvmsp-1 ICB 5-6 region from P. vivax isolates collected in 4 provinces of Vietnam (Dak Lak, Dak Nong, Gia Lai, and Khanh Hoa) between 2018 and 2022. A comparative analysis of pvmsp-1 ICB 5-6 sequences was also conducted between Vietnam and other endemic regions. A total of 139 pvmsp-1 ICB 5-6 sequences were obtained from 117 Vietnamese P. vivax isolates. Vietnam pvmsp-1 ICB 5-6 were clustered into 34 distinct haplotypes at the amino acid level, with the recombinant types being predominant. The pvmsp-1 ICB 5-6 from the Central Highlands, Dak Lak, Dak Nong, and Gia Lai, exhibited high genetic polymorphism, while the sequences from the South-Central region, Khanh Hoa, were less polymorphic. Highly diverse patterns of poly-glutamine (poly-Q) variants were identified in Vietnam pvmsp-1 ICB 5-6. Comparable features of genetic polymorphism were also identified in the global pvmsp-1 ICB 5-6 populations. Phylogenetic analysis of global pvmsp-1 ICB 5-6 revealed no significant country- or region-specific clustering. This study suggests that Vietnam pvmsp-1 ICB 5-6 exhibited a substantial genetic diversity with regional variations, implying the genetic heterogeneity of the Vietnamese P. vivax population. These findings emphasize the importance of continuous molecular surveillance to understand the genetic nature of the parasite in the country.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":" ","pages":"52-61"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nucleolar organization and divergent transcriptional machinery in Giardia lamblia: Structural insights and implications for drug targeting. 兰氏贾第鞭毛虫的核仁组织和不同的转录机制：结构见解和药物靶向的意义。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-29 DOI: 10.3347/PHD.25093

Carlos Gaona-López

引用次数: 0

Identification of maternal antibodies targeting a cystatin-like protein of Trichinella spiralis in offspring. 旋毛虫子代胞抑素样蛋白母源抗体的鉴定。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-14 DOI: 10.3347/PHD.25078

Minkyoung Cho, Hak Sun Yu

{"title":"Identification of maternal antibodies targeting a cystatin-like protein of Trichinella spiralis in offspring.","authors":"Minkyoung Cho, Hak Sun Yu","doi":"10.3347/PHD.25078","DOIUrl":"10.3347/PHD.25078","url":null,"abstract":"Vertical transfer of maternal antibodies can provide passive protection to offspring against specific pathogens. In this study, we detected antibodies in the sera of uninfected offspring born to chronically Trichinella spiralis-infected female mice. Immunoblotting consistently revealed a distinct band at ~38 kDa in both T. spiralis excretory-secretory products and total somatic extracts. This band was identified by MALDI-TOF/TOF mass spectrometry as a cystatin-like protein of T. spiralis (Ts-CLP). Structural modeling and domain analysis indicated a typical cystatin-like fold comprising a central α-helix and an antiparallel β-sheet core. To confirm antigen identity, recombinant Ts-CLP protein was expressed and used to generate a polyclonal anti-recombinant Ts-CLP protein antibody. This antibody specifically recognized a ~38 kDa band in T. spiralis excretory-secretory products and total somatic extracts, consistent with that detected by offspring sera. Collectively, these findings demonstrate that maternal antibodies specific to Ts-CLP are vertically transferred and detectable in uninfected offspring. Although the functional significance remains to be determined, this observation provides a basis for future studies on passive immunity and host-parasite interactions.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":" ","pages":"82-86"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IKK2, calcium, MAP kinase, and PI3 kinase are required for exocytosis and interleukin-8 production in human mast cells stimulated by Trichomonas vaginalis-derived secretory products. IKK2、钙、MAP激酶和PI3激酶是阴道毛滴虫分泌产物刺激人肥大细胞胞吐和白细胞介素-8产生所必需的。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-09 DOI: 10.3347/PHD.25079

Shin Hye Park, Young Ah Lee, Myeong Heon Shin

引用次数: 0

A human case of cercarial dermatitis and molecular characterization of Trichobilharzia cercariae from Radix plicatula of paddy field in Tokyo, Japan. 日本东京地区1例人子宫颈皮炎及水田根棘毛线虫分子特征分析。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-22 DOI: 10.3347/PHD.25039

Azusa Banzai, Hiromu Sugiyama, Kentaro Wada, Hirotaka Katahira, Rei Hirasawa, Ryota Tanabe, Sou Saito, Kunitaka Kobayashi

{"title":"A human case of cercarial dermatitis and molecular characterization of Trichobilharzia cercariae from Radix plicatula of paddy field in Tokyo, Japan.","authors":"Azusa Banzai, Hiromu Sugiyama, Kentaro Wada, Hirotaka Katahira, Rei Hirasawa, Ryota Tanabe, Sou Saito, Kunitaka Kobayashi","doi":"10.3347/PHD.25039","DOIUrl":"10.3347/PHD.25039","url":null,"abstract":"Avian schistosomes, mainly belonging to the genus Trichobilharzia, are the etiological agents of cercarial dermatitis in humans. The aims of this study were to report a human case of cercarial dermatitis contracted in a paddy field in a natural regeneration area in Tokyo, Japan, and identify the etiological agents of this case using molecular phylogenetic analyses. A snail survey was conducted between 2021 and 2023 in a rice paddy field where a case of cercarial dermatitis occurred, and molecular phylogenetic analyses of the furcocercariae and parasitized lymnaeid snails were performed based on the partial sequence of the mtDNA cox1 gene. Furcocercariae were detected in 11 (2.7%) of the 413 lymnaeid snails examined, and all 120 pleurocerid snails tested negative for cercariae. The cercarial larvae possessed a pair of eye spots and a characteristic bifurcated tail. Phylogenetic analyses of the cox1 genes identified the furcocercariae as Trichobilharzia sp., and the lymnaeid snails were Radix plicatula. This study demonstrated that the life cycle of a Trichobilharzia sp., using R. plicatula as an intermediate host, is established in an urban natural restoration area in Tokyo, serving as a source of human cercarial dermatitis. This study emphasizes the need for an increased awareness of cercarial dermatitis as a potential public health concern.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"64 1","pages":"18-26"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of Legionella pneumophila infection on the encystation of Acanthamoeba castellanii. 嗜肺军团菌感染对卡斯特棘阿米巴感染的影响。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-29 DOI: 10.3347/PHD.25080

Hye-Jeong Jo, Hae-Ahm Lee, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon

{"title":"The effect of Legionella pneumophila infection on the encystation of Acanthamoeba castellanii.","authors":"Hye-Jeong Jo, Hae-Ahm Lee, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon","doi":"10.3347/PHD.25080","DOIUrl":"10.3347/PHD.25080","url":null,"abstract":"Acanthamoeba is a genus of free-living amoebae commonly found in soil, water, and other habitats. This organism undergoes 2 distinct stages in its life cycle, the trophozoite and the cyst. Under adverse conditions, trophozoites transform into cysts, which are notably resistant to harsh physical and chemical conditions. Infected by Legionella pneumophila has been shown to decrease the number of cysts in its host Acanthamoeba species, although the mechanisms responsible for this effect remain poorly understood. In this study, A. castellanii was co-cultured with either L. pneumophila or Escherichia coli to assess the impact on encystation and to explore the genes involved in this process. Following a 72-h encystation induction period, it was observed that Acanthamoeba infected with Legionella exhibited a 45.8% reduction in cyst formation compared to the control group. In contrast, Acanthamoeba that phagocytosed E. coli showed a 21.7% decrease. To identify the genes involved in this phenomenon, real-time PCR analysis was conducted on 20 genes known to be upregulated during encystation. This analysis was performed to verify their expression patterns at 24, 48, and 72 h. Notably, ten genes, including cyst-specific protein 21, glycosyltransferase, RSNARE, and cellulose synthase, did not exhibit increased expression in Legionella-infected Acanthamoeba. However, these genes showed elevated expression levels in both the control group and the bacteria-phagocytosed Acanthamoeba. This suggests that several cellular processes, including cell wall formation, are inhibited in Acanthamoeba infected with Legionella, resulting in reduced encystation.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"64 1","pages":"37-44"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feline heartworm (Dirofilaria immitis) infection in stray cats in Ulsan, Korea. 韩国蔚山流浪猫感染猫心丝虫。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-22 DOI: 10.3347/PHD.25076

Jihyun Kim, Miryeng Kim, Seungjin Lee, Youngmin Yun

{"title":"Feline heartworm (Dirofilaria immitis) infection in stray cats in Ulsan, Korea.","authors":"Jihyun Kim, Miryeng Kim, Seungjin Lee, Youngmin Yun","doi":"10.3347/PHD.25076","DOIUrl":"10.3347/PHD.25076","url":null,"abstract":"Feline heartworm (Dirofilaria immitis) infection is an uncommon but clinically significant disease in Korea. A retrospective review of electronic medical records from a secondary referral animal hospital in Ulsan, Korea, identified 2 antigen-positive (1.5%) cases among 130 stray cats tested between 2019 and 2023, while no infections were detected in 298 client-owned cats. As antigen testing may yield false-negative results in cats with male-only infections, the true prevalence is likely underestimated. This report describes the clinical and echocardiographic findings of 2 infected stray cats. Case 1 involved successful long-term management of heartworm-associated respiratory disease, with the cat remaining healthy for 4 years following diagnosis. Case 2 demonstrated persistent evidence of adult heartworms and sudden death after an asymptomatic period of 1 year. Echocardiography in Case 2 revealed multiple hyperechoic double lines within the pulmonary arteries, consistent with intraluminal adult worms. These cases illustrate the diagnostic challenges and variable clinical outcomes of feline heartworm infection, emphasizing the need for increased awareness in Korea.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"64 1","pages":"92-97"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First record of 3 chewing louse species from the Oriental stork (Ciconia boyciana) in Korea: Insights into conservation of co-associated species. 韩国东方鹳（Ciconia boyciana） 3种咀嚼虱的首次记录：对共亲缘种保护的见解。

IF 1.3

Parasites, hosts and diseases Pub Date : 2026-01-01 Epub Date: 2026-01-14 DOI: 10.3347/PHD.25070

Jeong Hun Shim, Seongjun Choe, Sukyung Kim, Dongsoo Ha, Soo Hyung Eo

{"title":"First record of 3 chewing louse species from the Oriental stork (Ciconia boyciana) in Korea: Insights into conservation of co-associated species.","authors":"Jeong Hun Shim, Seongjun Choe, Sukyung Kim, Dongsoo Ha, Soo Hyung Eo","doi":"10.3347/PHD.25070","DOIUrl":"10.3347/PHD.25070","url":null,"abstract":"The Oriental stork (Ciconia boyciana Swinhoe, 1873) is an endangered species, with active restoration efforts ongoing in Korea. Despite the ecological importance of host-specific parasites, such as chewing lice (Phthiraptera), information on the chewing lice fauna associated with C. boyciana in Korea remains unclear. Previous records of 2 chewing louse species from the host have been questioned due to potential misidentification. To clarify the chewing lice fauna of the host, we conducted a survey of captive C. boyciana at Yesan Oriental Stork Park, Korea, in October 2022. Morphological identification of collected louse specimens revealed 3 species: Neophilopterus incompletes (Denny, 1842), Ardeicola ciconiae (Linnaeus, 1758) and Colpocephalum zebra Burmeister, 1838. These species are typical ectoparasites of Ciconiiform birds and represent the first verified louse records of chewing lice from C. boyciana in Korea. Unlike with a previous report, Cuclotogaster heterographus (Nitzsch, 1866) and Anaticola anseris (Linnaeus, 1758) were not detected. Our findings provide an updated checklist of chewing louse species for C. boyciana in Korea, contributing to a more accurate understanding of host-parasite associations and supporting future conservation efforts for both the host and its associated parasite fauna.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":" ","pages":"87-91"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0