Parasites, hosts and diseases最新文献_第10页

Diagnosing Balamuthia mandrillaris amebic meningoencephalitis in a 64-year-old woman from the Southwest of China. 中国西南地区1例64岁妇女阿米巴氏脊膜脑炎的诊断

Parasites, hosts and diseases Pub Date : 2023-05-01 DOI: 10.3347/PHD.23039

Suhua Yao, Xiaoting Chen, Lian Qian, Shizheng Sun, Chunjing Zhao, Zongkai Bai, Zhaofang Chen, Youcong Wu

{"title":"Diagnosing Balamuthia mandrillaris amebic meningoencephalitis in a 64-year-old woman from the Southwest of China.","authors":"Suhua Yao, Xiaoting Chen, Lian Qian, Shizheng Sun, Chunjing Zhao, Zongkai Bai, Zhaofang Chen, Youcong Wu","doi":"10.3347/PHD.23039","DOIUrl":"https://doi.org/10.3347/PHD.23039","url":null,"abstract":"Balamuthia mandrillaris amebic encephalitis (BAE) can cause a fatal condition if diagnosis is delayed or effective treatment is lacking. Patients with BAE have been previously reported in 12 provinces of China, with skin lesions being the primary symptom and encephalitis developing after several years. However, a significantly lower number of cases has been reported in Southwest China. Here we report an aggressive BAE case of a 64-year-old woman farmer with a history of skin lesions on her left hand. She was admitted to our hospital due to symptoms of dizziness, headache, cough, vomiting, and gait instability. She was initially diagnosed with syphilitic meningoencephalitis and received a variety of empirical treatment that failed to improve her symptoms. Finally, she was diagnosed with BAE combined with amebic pneumonia using next-generation sequencing (NGS), qRT-PCR, sequence analysis, and imaging studies. She died approximately 3 weeks after the onset. This case highlights that the rapid development of encephalitis can be a prominent clinical manifestation of Balamuthia mandrillaris infection.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 2","pages":"183-193"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/37/55/phd-23039.PMC10234826.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9620307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lophomonas blattarum-like organism in bronchoalveolar lavage from a pneumonia patient: current diagnostic scheme and polymerase chain reaction can lead to false-positive results. 肺炎患者支气管肺泡灌洗液中的blattarm样生物:目前的诊断方案和聚合酶链反应可导致假阳性结果。

Parasites, hosts and diseases Pub Date : 2023-05-01 DOI: 10.3347/PHD.22107

Moses Lee, Sang Mee Hwang, Jong Sun Park, Jae Hyeon Park, Jeong Su Park

{"title":"Lophomonas blattarum-like organism in bronchoalveolar lavage from a pneumonia patient: current diagnostic scheme and polymerase chain reaction can lead to false-positive results.","authors":"Moses Lee, Sang Mee Hwang, Jong Sun Park, Jae Hyeon Park, Jeong Su Park","doi":"10.3347/PHD.22107","DOIUrl":"https://doi.org/10.3347/PHD.22107","url":null,"abstract":"Lophomonas blattarum is an anaerobic protozoan living in the intestine of cockroaches and house dust mites, with ultramicroscopic characteristics such as the presence of a parabasal body, axial filament, and absence of mitochondria. More than 200 cases of Lophomonas infection of the respiratory tract have been reported worldwide. However, the current diagnosis of such infection depends only on light microscopic morphological findings from respiratory secretions. In this study, we attempted to provide more robust evidence of protozoal infection in an immunocompromised patient with atypical pneumonia, positive for Lophomonas-like protozoal cell forms. A direct search of bronchoalveolar lavage fluid via polymerase chain reaction (PCR), transmission electron microscopy (TEM), and metagenomic next-generation sequencing did not prove the presence of protozoal infection. PCR results were not validated with sufficient rigor, while de novo assembly and taxonomic classification results did not confirm the presence of an unidentified pathogen. The TEM results implied that such protozoal forms in light microscopy are actually non-detached ciliated epithelial cells. After ruling out infectious causes, the patient's final diagnosis was drug-induced pneumonitis. These findings underscore the lack of validation in the previously utilized diagnostic methods, and more evidence in the presence of L. blattarum is required to further prove its pathogenicity.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 2","pages":"202-209"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f7/49/phd-22107.PMC10234821.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9620310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular detection and genotype analysis of Kudoa septempunctata from food poisoning outbreaks in Korea. 韩国食物中毒事件中七星虫的分子检测和基因型分析。

Parasites, hosts and diseases Pub Date : 2023-02-01 DOI: 10.3347/PHD.22034

Gyung-Hye Sung, In-Ji Park, Hee-Soo Koo, Eun-Hee Park, Mi-Ok Lee

{"title":"Molecular detection and genotype analysis of Kudoa septempunctata from food poisoning outbreaks in Korea.","authors":"Gyung-Hye Sung, In-Ji Park, Hee-Soo Koo, Eun-Hee Park, Mi-Ok Lee","doi":"10.3347/PHD.22034","DOIUrl":"https://doi.org/10.3347/PHD.22034","url":null,"abstract":"Concerns about foodborne illnesses caused by Kudoa septempunctata are steadily growing, but reports of K. septempunctata in clinical and food specimens related to food poisoning in Korea are limited. This study aimed to genetically identify K. septempunctata in patients with acute diarrhea and in clinical and food samples related to food poisoning caused by sashimi consumption. Both real-time and nested polymerase chain reaction assays were performed to detect K. septempunctata 18S and 28S rDNA genes in the stools of 348 patients with acute diarrhea, 11 samples (6 stool and 5 rectal swab samples) from patients with food poisoning, and 2 raw Paralichthys olivaceus samples collected from a restaurant where a food poisoning incident occurred. K. septempunctata was identified in 5 clinical specimens (4 stools and 1 rectal swab) and 1 P. olivaceus sashimi sample. All detected K. septempunctata were of genotype ST3. This is the first study to identify K. septempunctata in both patients and food samples with epidemiological relevance in Korea, providing evidence that it is a pathogen that causes food poisoning. Also, this is the first study to confirm the presence of K. septempunctata genes in rectal swabs. Despite continuing suspected occurrences of Kudoa foodborne outbreaks, the rate of identification of K. septempunctata is very low. One reason for this is the limitation in obtaining stool and vomit samples for the diagnosis of Kudoa infection. We strongly suggest the inclusion of rectal swabs among the diagnostic specimens for Kudoa food poisoning.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 1","pages":"15-23"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e3/f6/phd-22034.PMC10230659.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9543739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular sparganosis: comment. 眼部疏松症：评论。

Parasites, hosts and diseases Pub Date : 2023-02-01 Epub Date: 2023-02-22 DOI: 10.3347/PHD.23005

Amnuay Kleebayoon, Viroj Wiwanitkit

引用次数: 0

Updates on parasite infection prevalence in the Joseon period based on parasitological studies of human coprolites isolated from archaeological sites in the cities of Euijeongbu, Gumi, and Wonju. 根据义政府、龟尾和原州考古遗址中分离的人类粪化石的寄生虫学研究，对朝鲜时期寄生虫感染流行情况的最新研究。

Parasites, hosts and diseases Pub Date : 2023-02-01 DOI: 10.3347/PHD.22129

Chang Seok Oh, Jong-Yil Chai, Sori Min, Kyong Taek Oh, Jeonghwan Seol, Mi Kyung Song, Dong Hoon Shin, Min Seo

{"title":"Updates on parasite infection prevalence in the Joseon period based on parasitological studies of human coprolites isolated from archaeological sites in the cities of Euijeongbu, Gumi, and Wonju.","authors":"Chang Seok Oh, Jong-Yil Chai, Sori Min, Kyong Taek Oh, Jeonghwan Seol, Mi Kyung Song, Dong Hoon Shin, Min Seo","doi":"10.3347/PHD.22129","DOIUrl":"https://doi.org/10.3347/PHD.22129","url":null,"abstract":"Parasite infection rates estimated by examining ancient coprolites can provide insights into parasitism in Joseon society. Using newly discovered Joseon period cases is essential to regularly update the parasite infection rates and reinforce the reliability of our previous estimations. In the present study, we investigated parasite infections in Joseon coprolites newly isolated from the cities of Euijeongbu, Gumi, and Wonju. We then updated the overall parasite infection rates of Joseon period samples (n= 30) as follows: 86.7% (26/30) for Trichuris trichiura, 56.7% (17/30) for Ascaris lumbricoides, 30.0% (9/30) for Clonorchis sinensis, and 30.0% (9/30) for Paragonimus westermani. The parasite infection rates in the Joseon society, estimated through coprolite examination, were very similar to those determined previously despite the addition of new cases to the existing data pool.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 1","pages":"89-93"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/0c/phd-22129.PMC10230661.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory response to Trichomonas vaginalis in the pathogenesis of prostatitis and benign prostatic hyperplasia. 阴道毛滴虫炎症反应在前列腺炎和良性前列腺增生发病机制中的作用。

Parasites, hosts and diseases Pub Date : 2023-02-01 DOI: 10.3347/PHD.22160

Ik-Hwan Han, Jung-Hyun Kim, Jae-Sook Ryu

{"title":"Inflammatory response to Trichomonas vaginalis in the pathogenesis of prostatitis and benign prostatic hyperplasia.","authors":"Ik-Hwan Han, Jung-Hyun Kim, Jae-Sook Ryu","doi":"10.3347/PHD.22160","DOIUrl":"https://doi.org/10.3347/PHD.22160","url":null,"abstract":"Trichomonas vaginalis is a flagellated protozoan that causes trichomoniasis, a common nonviral sexually transmitted infection. T. vaginalis infection is asymptomatic in most infected men but can lead to chronic infection. The inflammatory response to chronic T. vaginalis infection may contribute to prostatic diseases, such as prostatitis and benign prostatic hyperplasia (BPH); however, studies on the relationship between T. vaginalis infection and prostate diseases are scarce. In this review, we discuss evidence from our studies on the involvement of T. vaginalis in the pathogenesis of prostate diseases, such as prostatitis and BPH. Studies of prostatitis have demonstrated that the attachment of T. vaginalis trophozoite to prostate epithelial cells (PECs) induces inflammatory cytokine production and inflammatory cell migration, leading to prostatitis. T. vaginalis also causes pathological changes, such as inflammatory cell infiltration, acinar changes, interstitial fibrosis, and mast cell infiltration, in prostate tissues of infected rats. Thus, T. vaginalis is considered an infectious agent that triggers prostatitis. Meanwhile, studies of prostatic hyperplasia revealed that mast cells activated by T. vaginalis-infected prostate cells secreted inflammatory mediators, such as β-hexosaminidase and tryptase, which promoted proliferation of prostate stromal cell (PSC). Moreover, interleukin-6 produced by proliferating PSCs induced the multiplication of BPH-1 epithelial cells as a result of stromal-epithelial interaction, suggesting that the proliferation of T. vaginalis-infected prostate cells can be induced through crosstalk with mast cells. These collective findings suggest that T. vaginalis contributes to the progression of prostatitis and prostatic hyperplasia by creating an inflammatory microenvironment involving PECs and PSCs.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 1","pages":"2-14"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/94/phd-22160.PMC10230662.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9555383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of head louse infestation among primary schoolchildren in the Republic of Korea: nationwide observation of trends in 2011-2019. 大韩民国小学生头虱感染率：2011-2019 年全国趋势观察。

Parasites, hosts and diseases Pub Date : 2023-02-01 Epub Date: 2023-02-22 DOI: 10.3347/PHD.22134

Seungwan Ryoo, Sooji Hong, Taehee Chang, Hyejoo Shin, Jae Young Park, Jeonggyu Lee, Eun-Hee Nah, Eun Hee Lee, Bong-Kwang Jung, Jong-Yil Chai

{"title":"Prevalence of head louse infestation among primary schoolchildren in the Republic of Korea: nationwide observation of trends in 2011-2019.","authors":"Seungwan Ryoo, Sooji Hong, Taehee Chang, Hyejoo Shin, Jae Young Park, Jeonggyu Lee, Eun-Hee Nah, Eun Hee Lee, Bong-Kwang Jung, Jong-Yil Chai","doi":"10.3347/PHD.22134","DOIUrl":"10.3347/PHD.22134","url":null,"abstract":"Head louse infestation is a significant public health problem across the world, particularly among preschool and primary schoolchildren. This study investigated the trends of head louse infestation in the Republic of Korea over a 9-year period (2011-2019), targeting primary schoolchildren in 3 areas of Seoul, 4 other large cities, and 9 provinces. A survey was administered annually by the health staff of each regional office (n= 16) of the Korea Association of Health Promotion (KAHP). The branch offices of KAHP examined a total of 51,508 primary schoolchildren, comprising 26,532 boys and 24,976 girls. Over the 9-year survey, a total of 1,107 (2.1%) schoolchildren tested positive for adults and/or nits of Pediculus humanus capitis. The prevalence was 2.8% (133/4,727) in 2011-2012 and gradually decreased to 0.8% (49/6,461) in 2019 (P< 0.05). Head lice were found more frequently in girls (3.0%; 746/24,976) than in boys (1.4%; 361/26,532) (P< 0.05). In terms of geographic localities, the highest infestation rate, 4.7% (average prevalence over 9 years), was observed in southern Seoul (Gangnam branch of KAHP), whereas the lowest infestation rate, 0.7%, was seen in Gyeongsang (north and south provinces) and western Seoul. Although the prevalence decreased significantly during the 9-year period, head louse infestation remains a health and hygiene issue among primary schoolchildren in the Republic of Korea. Regular surveys along with health education are needed to further improve children's hair hygiene.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 1","pages":"53-59"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/db/b7/phd-22134.PMC10230657.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic diversity of Plasmodium falciparum erythrocyte membrane protein 1 in field isolates from central Myanmar. 缅甸中部地区恶性疟原虫红细胞膜蛋白1的遗传多样性

Parasites, hosts and diseases Pub Date : 2023-02-01 DOI: 10.3347/PHD.22165

Sylvatrie-Danne Dinzouna-Boutamba, Sanghyun Lee, Zin Moon, Dong-Il Chung, Yeonchul Hong, Moe Kyaw Myint, Haung Naw, Byoung-Kuk Na, Youn-Kyoung Goo

引用次数: 1

Positive rates for Enterobius vermicularis eggs among preschool children in Yeosu-si, Jeollanam-do, Korea (2017-2021). 全罗南道丽水市学龄前儿童蛲虫卵阳性率(2017-2021年)

Parasites, hosts and diseases Pub Date : 2023-02-01 DOI: 10.3347/PHD.22121

Myoung-Ro Lee, Hee-Eun Shin, Seon-Ok Back, Young-Ju Lee, Jung-Won Ju, Chun Soon Park, Hee-Il Lee

{"title":"Positive rates for Enterobius vermicularis eggs among preschool children in Yeosu-si, Jeollanam-do, Korea (2017-2021).","authors":"Myoung-Ro Lee, Hee-Eun Shin, Seon-Ok Back, Young-Ju Lee, Jung-Won Ju, Chun Soon Park, Hee-Il Lee","doi":"10.3347/PHD.22121","DOIUrl":"https://doi.org/10.3347/PHD.22121","url":null,"abstract":"This study aimed to evaluate the positive rates for Enterobius vermicularis eggs among preschool children in Yeosu-si, Jeollanam-do, the Republic of Korea (Korea) over a period of 5 years (2017-2021). Perianal swab samples, obtained using cellotape, from 10,392 preschool children in 26 districts were examined microscopically for E. vermicularis eggs. The test results were notified through the local health center, and the families of children who tested positive were advised to provide them anthelmintics treatment. The annual positive rates were 5.0%, 5.2%, 4.4%, 2.2%, and 1.0% in 2017, 2018, 2019, 2020, and 2021, respectively. The overall positive rate was higher in boys than in girls (P< 0.05), and children aged 5-7 years were at a higher risk of being infected than those aged 0-4 years (P< 0.05). Although the rates of infection by E. vermicularis in the survey area, Yeosu-si, were still in the 1% range , the results of this study suggest that they can be significantly reduced through continuous intervention centered around the test-treatment strategy.","PeriodicalId":74397,"journal":{"name":"Parasites, hosts and diseases","volume":"61 1","pages":"84-88"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c5/b0/phd-22121.PMC10230655.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9549912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imported human babesiosis in the Republic of Korea, 2019: two case reports. 2019年韩国输入性人间巴贝斯虫病:两例报告

Parasites, hosts and diseases Pub Date : 2023-02-01 DOI: 10.3347/PHD.22168

Hyun Jung Kim, Min Jae Kim, Hyun-Il Shin, Jung-Won Ju, Hee-Il Lee

引用次数: 0