Osteoarthritis and cartilage open最新文献

{"title":"Optimizing osteoarthritis care through clinical and community partnership: Results of an exploratory trial","authors":"Kelli D. Allen ,&nbsp;Liubov Arbeeva ,&nbsp;Leigh F. Callahan ,&nbsp;Katherine Combs ,&nbsp;Tamara Godfrey ,&nbsp;Yvonne M. Golightly ,&nbsp;Derek Hales ,&nbsp;Carla Hill ,&nbsp;Katie F. Huffman ,&nbsp;Amanda E. Nelson ,&nbsp;Jennifer Rees ,&nbsp;Todd A. Schwartz","doi":"10.1016/j.ocarto.2025.100588","DOIUrl":"10.1016/j.ocarto.2025.100588","url":null,"abstract":"<div><h3>Background/Purpose</h3><div>To conduct an exploratory trial of a clinic-community care model (OA CARE) for managing osteoarthritis (OA).</div></div><div><h3>Design</h3><div>Participants (n ​= ​60) with symptomatic knee or hip OA and overweight/obesity were randomized to OA CARE or a usual care control group (UC). Participants in the OA CARE group received a 12-month medical membership to a local YMCA, which included a 12-week weight loss program and access to exercise programming, as well as referrals to rehabilitation, nutrition, sleep-related and psychological services. Participants’ primary care clinicians were given a video-based summary of OA treatment guidelines. Feasibility metrics included engagement with the weight loss program and exercise resources. Outcomes were assessed at baseline, 6-months and 12-months. The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Outcomes were analyzed between groups across time points using general linear mixed models.</div></div><div><h3>Results</h3><div>Eighty-seven percent of the OA CARE group participated in the weight loss program, with a mean attendance of 9.2 sessions; 57 ​% participated in an exercise class. At 6-months, there was a statistically significant between-group difference in change in WOMAC total scores, with the OA CARE group showing greater improvement (−11.0, 95 ​% Confidence Interval −20.1, −1.9). At 12-months, the between-group change in WOMAC score was not statistically significant, though there was a small difference in favor of OA CARE Group (−4.9, 95 ​% Confidence Interval −14.1, 4.3).</div></div><div><h3>Conclusion</h3><div>Feasibility metrics were positive, but effects of OA CARE were modest, and a more intensive approach may be needed to enhance impacts.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100588"},"PeriodicalIF":0.0,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explanatory factors for the survival benefit among hip and knee arthroplasty patients with osteoarthritis","authors":"Jan M. Heijdra Suasnabar ,&nbsp;Maaike Gademan ,&nbsp;Liza van Steenbergen ,&nbsp;Ewout Steyerberg ,&nbsp;Rob Nelissen ,&nbsp;Wilbert van den Hout","doi":"10.1016/j.ocarto.2025.100587","DOIUrl":"10.1016/j.ocarto.2025.100587","url":null,"abstract":"<div><h3>Objective</h3><div>Studies have shown that osteoarthritis patients who underwent a primary total hip or knee arthroplasty (THA/TKA) experience better survival than the general population, yet there is limited evidence explaining this counter-intuitive difference. We investigated whether this better survival is also present in the Netherlands and to what extent it could be explained by a patient selection effect, whereby patients with more favorable health and socioeconomic status (SES) are more likely to receive THA/TKA.</div></div><div><h3>Design</h3><div>In this registry-based study, we compared the survival, health and SES of THA/TKA osteoarthritis patients to those of the general Dutch population. The patient cohort included 224,785 THA and 198,691 TKA patients who underwent an arthroplasty between 2010–2020. The proportions of the survival differences explained by better health (as measured by the EQ-5D) and SES (postcode-level) were estimated using spline-based survival models and Dutch lifetables.</div></div><div><h3>Results</h3><div>The eleven-year survival of THA and TKA patients were 8.7% and 8.1% better than the general population. Although health and SES predicted individual survival, they explained only ≈7% of the survival benefit.</div></div><div><h3>Conclusions</h3><div>Our study confirmed that Dutch osteoarthritis THA/TKA patients experience better survival than the general population, but raises important questions as to the explanation. A more favorable health status and/or SES did not explain most of the survival benefit. This may be partly due to limitations of the available measures of health and SES in our study, but also leaves other explanations (e.g. barriers to receive access to care, lifestyle changes) open for further research.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100587"},"PeriodicalIF":0.0,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients with unilateral patellofemoral pain have altered bone turnover in the painful knee compared to the pain-free knee at rest and after acute knee loading","authors":"Rudi Hansen ,&nbsp;Bryan Haddock ,&nbsp;René B. Svensson ,&nbsp;Markus Nowak Lonsdale ,&nbsp;Lisbeth Marner ,&nbsp;Lene Rørdam ,&nbsp;Inge Lise Rasmussen ,&nbsp;Christoffer Brushøj ,&nbsp;S. Peter Magnusson ,&nbsp;Marius Henriksen ,&nbsp;Christian Couppé","doi":"10.1016/j.ocarto.2025.100583","DOIUrl":"10.1016/j.ocarto.2025.100583","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to investigate subchondral bone turnover at rest and after acute loading using Fluorine-18-labeled sodium fluoride (Na[¹⁸F]F) Positron Emission Tomography (PET), in patients with unilateral PFP.</div></div><div><h3>Design</h3><div>Twenty-seven patients with unilateral PFP were recruited from the Institute of Sports Medicine Copenhagen. Participants underwent Na[¹⁸F]F-PET imaging before and after a bout of single-leg squats. Bone turnover measures, including mean and maximal standardized uptake value (SUV_mean and SUV_max), rate of bone perfusion (K1), rate of tracer uptake into bone (Ki), and extraction fraction of tracer absorbed into bone mineral were assessed for patella and trochlea.</div></div><div><h3>Results</h3><div>At rest, the painful knees showed lower SUV_max, K₁, and K_i compared to the pain-free knees in the superficial part of the patella. No significant differences were found in the profound part of the patella or trochlea at rest. Following knee loading, the acute increases in SUV_mean, SUV_max, K_i and blood flow were reduced in the superficial patella of the painful knees compared to the pain-free knees. In the trochlea, painful knees showed larger increases in SUV_mean and K_i in the lateral part, whereas the medial part showed greater increases in K₁, K_i, and a larger decrease in extraction fraction after loading.</div></div><div><h3>Conclusion</h3><div>Patella displayed decreased bone metabolism at rest and reduced response to loading in the painful versus pain-free knees. Trochlea in the painful knees showed significantly larger increases in subchondral bone metabolism following knee loading compared to the pain-free knees. These novel findings highlight potential differences in bone turnover between the patellar and trochlear regions.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100583"},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contralateral knee osteoarthritis severity relates to magnetic resonance imaging findings in knees with and without osteoarthritis: Data from the osteoarthritis initiative","authors":"Jeffrey B. Driban ,&nbsp;Jonggyu Baek ,&nbsp;Julieann C. Patarini ,&nbsp;Emily Kirillov ,&nbsp;Nhung Vo ,&nbsp;Michael J. Richard ,&nbsp;Ming Zhang ,&nbsp;Matthew S. Harkey ,&nbsp;Grace H. Lo ,&nbsp;Shao-Hsien Liu ,&nbsp;Charles B. Eaton ,&nbsp;Jamie MacKay ,&nbsp;Mary F. Barbe ,&nbsp;Timothy E. McAlindon","doi":"10.1016/j.ocarto.2025.100585","DOIUrl":"10.1016/j.ocarto.2025.100585","url":null,"abstract":"<div><h3>Objective</h3><div>We explored whether a magnetic resonance imaging (MRI)-based composite score of bone marrow lesion and effusion-synovitis volumes related to contralateral knee osteoarthritis disease severity.</div></div><div><h3>Design</h3><div>Using data from the Osteoarthritis Initiative, we conducted cross-sectional knee-based analyses among participants with bilateral knee MRIs and at least one knee with Kellgren–Lawrence (KL) grade ≥1 and a WOMAC pain score ≥10/100 (n ​= ​693). Bone marrow lesion and effusion-synovitis volumes on MRIs were used to calculate a composite score (“disease activity”). We divided the disease activity score into tertiles. We used multinomial logistic models to explore the association between disease activity in knees with and without radiographic osteoarthritis (outcome) and the contralateral disease severity (KL grade or disease activity; exposure).</div></div><div><h3>Results</h3><div>We included 1386 knees from participants with an average age of 62 (standard deviation ​= ​9) years. Most participants were overweight and had mild-to-moderate radiographic osteoarthritis. Disease activity among knees without radiographic osteoarthritis had statistically significant relationships with contralateral disease activity (range of odds ratios: 4.86–23.22) but not contralateral KL grade (range of odds ratios: 0.86–1.01). Disease activity among knees with radiographic osteoarthritis had statistically significant relationships with contralateral disease activity and KL grade; however, the association was stronger for contralateral disease activity than KL grade (range of odds ratios: 3.67–21.29 versus 1.96–2.20).</div></div><div><h3>Conclusion</h3><div>Structural findings in one knee may relate to structural findings in the other knee. This highlights the need for future studies to explore how the contralateral knee could impact clinical trial screening, monitoring, and intervention strategies, especially when testing localized therapies.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100585"},"PeriodicalIF":0.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143478680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive validity of consensus-based MRI definition of osteoarthritis plus radiographic osteoarthritis for the progression of knee osteoarthritis: A longitudinal cohort study","authors":"Xing Xing ,&nbsp;Yining Wang ,&nbsp;Jianan Zhu ,&nbsp;Ziyuan Shen ,&nbsp;Flavia Cicuttini ,&nbsp;Graeme Jones ,&nbsp;Dawn Aitken ,&nbsp;Guoqi Cai","doi":"10.1016/j.ocarto.2025.100582","DOIUrl":"10.1016/j.ocarto.2025.100582","url":null,"abstract":"<div><h3>Objective</h3><div>Our previous study showed that magnetic resonance imaging (MRI)-defined tibiofemoral osteoarthritis (MRI-OA), based on a Delphi approach, in combination with radiographic OA (ROA) had a strong predictive validity for the progression of knee OA. This study aimed to compare whether the combination using traditional prediction models was superior to the Light Gradient Boosting Machine (LightGBM) models.</div></div><div><h3>Methods</h3><div>Data were from the Tasmanian Older Adult Cohort. A radiograph and 1.5T MRI of the right knee was performed. Tibial cartilage volume was measured at baseline, 2.6 and 10.7 years. Knee pain and function were assessed at baseline, 2.6, 5.1, and 10.7 years. Right-sided total knee replacement (TKR) were assessed over 13.5 years. The area under the curve (AUC) was applied to compare the predictive validity of logistic regression with the LightGBM algorithm. For significant imbalanced outcomes, the area under the precision-recall curve (AUC-PR) was used.</div></div><div><h3>Results</h3><div>574 participants (mean 62 years, 49 ​% female) were included. Overall, the LightGBM showed a clinically acceptable predictive performance for all outcomes but TKR. For knee pain and function, LightGBM showed better predictive performance than logistic regression model (AUC: 0.731–0.912 vs 0.627–0.755). Similar results were found for tibial cartilage loss over 2.6 (AUC: 0.845 vs 0.701, p ​&lt; ​0.001) and 10.7 years (AUC: 0.845 vs 0.753, p ​= ​0.016). For TKR, which exhibited significant class imbalance, both algorithms performed poorly (AUC-PR: 0.647 vs 0.610).</div></div><div><h3>Conclusion</h3><div>Compared to logistic regression combining MRI-OA, ROA, and common covariates, LightGBM offers valuable insights that can inform early risk identification and targeted prevention strategies.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100582"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143446074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived barriers and facilitators to exercise adherence in osteoarthritis: A thematic synthesis of qualitative studies","authors":"Benedetto Giardulli ,&nbsp;Davide Marazzi ,&nbsp;Alessandro Nespoli ,&nbsp;Gaia Leuzzi ,&nbsp;Andrea Dell'Isola ,&nbsp;Yeliz Prior ,&nbsp;Simone Battista","doi":"10.1016/j.ocarto.2025.100584","DOIUrl":"10.1016/j.ocarto.2025.100584","url":null,"abstract":"<div><h3>Objective</h3><div>Exercise is a first-line intervention for osteoarthritis (OA). However, exercise adherence remains low, and existing studies exploring factors influencing adherence have yielded inconclusive results based on quantitative data. This study aims to synthesise qualitative studies focused on the perceived facilitators and barriers affecting exercise adherence in individuals with OA.</div></div><div><h3>Design</h3><div>A thematic synthesis of qualitative studies was conducted. Relevant articles were sourced from MEDLINE, Cochrane Central Register of Controlled Trials, Embase, CINAHL, and PsychInfo until November 2024. Studies focused on adults (≥16 years) with hip or knee OA who had participated in exercise programmes to manage OA. The quality of the studies was assessed using the Critical Appraisal Skills Programme (CASP) tool. Data analysis followed Thematic Synthesis by Thomas &amp; Harden to identify descriptive and analytical themes. The confidence of the evidence was evaluated through the Confidence in Evidence from Reviews of Qualitative Research (CERQual).</div></div><div><h3>Results</h3><div>A total of 21 studies involving 458 participants were included. From seven descriptive themes, three analytical themes were developed: (i) Mind-Body Connection, (ii) Social Support Systems, and (iii) Environmental Enablers. These themes underscore the importance of personal beliefs, experiences, and mindsets, alongside social and environmental factors, in promoting or hindering exercise adherence.</div></div><div><h3>Conclusion</h3><div>This study highlights the multifaceted cognitive, social, and environmental factors influencing exercise adherence in individuals with OA. The findings suggest that a ‘one-size-fits-all’ approach is insufficient for promoting sustained exercise engagement. Future quantitative research should build upon these insights to develop tailored strategies for enhancing exercise adherence in people with OA.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100584"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143452935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acknowledgement to Reviewers 2024","authors":"","doi":"10.1016/j.ocarto.2025.100581","DOIUrl":"10.1016/j.ocarto.2025.100581","url":null,"abstract":"","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 1","pages":"Article 100581"},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143422620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kellgren-Lawrence grading of knee osteoarthritis using deep learning: Diagnostic performance with external dataset and comparison with four readers","authors":"Elias Vaattovaara ,&nbsp;Egor Panfilov ,&nbsp;Aleksei Tiulpin ,&nbsp;Tuukka Niinimäki ,&nbsp;Jaakko Niinimäki ,&nbsp;Simo Saarakkala ,&nbsp;Mika T. Nevalainen","doi":"10.1016/j.ocarto.2025.100580","DOIUrl":"10.1016/j.ocarto.2025.100580","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the performance of a deep learning (DL) model in an external dataset to assess radiographic knee osteoarthritis using Kellgren-Lawrence (KL) grades against versatile human readers.</div></div><div><h3>Materials and methods</h3><div>Two-hundred-eight knee anteroposterior conventional radiographs (CRs) were included in this retrospective study. Four readers (three radiologists, one orthopedic surgeon) assessed the KL grades and consensus grade was derived as the mean of these. The DL model was trained using all the CRs from Multicenter Osteoarthritis Study (MOST) and validated on Osteoarthritis Initiative (OAI) dataset and then tested on our external dataset. To assess the agreement between the graders, Cohen's quadratic kappa (k) with 95 ​% confidence intervals were used. Diagnostic performance was measured using confusion matrices and receiver operating characteristic (ROC) analyses.</div></div><div><h3>Results</h3><div>The multiclass (KL grades from 0 to 4) diagnostic performance of the DL model was multifaceted: sensitivities were between 0.372 and 1.000, specificities 0.691–0.974, PPVs 0.227–0.879, NPVs 0.622–1.000, and AUCs 0.786–0.983. The overall balanced accuracy was 0.693, AUC 0.886, and kappa 0.820. If only dichotomous KL grading (i.e. KL0-1 vs. KL2-4) was utilized, superior metrics were seen with an overall balanced accuracy of 0.902 and AUC of 0.967. A substantial agreement between each reader and DL model was found: the inter-rater agreement was 0.737 [0.685–0.790] for the radiology resident, 0.761 [0.707–0.816] for the musculoskeletal radiology fellow, 0.802 [0.761–0.843] for the senior musculoskeletal radiologist, and 0.818 [0.775–0.860] for the orthopedic surgeon.</div></div><div><h3>Conclusion</h3><div>In an external dataset, our DL model can grade knee osteoarthritis with diagnostic accuracy comparable to highly experienced human readers.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 2","pages":"Article 100580"},"PeriodicalIF":0.0,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic syndrome is associated with more pain in hand osteoarthritis: Results from the DIGICOD cohort","authors":"Alix Charton ,&nbsp;Romane Lacoste-Badie ,&nbsp;Sophie Tuffet ,&nbsp;Alexandra Rousseau ,&nbsp;Emmanuel Maheu ,&nbsp;Bruno Fautrel ,&nbsp;Maxime Dougados ,&nbsp;Francis Berenbaum ,&nbsp;Alice Courties ,&nbsp;Jérémie Sellam","doi":"10.1016/j.ocarto.2025.100573","DOIUrl":"10.1016/j.ocarto.2025.100573","url":null,"abstract":"<div><h3>Background</h3><div>The role of metabolic syndrome (MetS) in osteoarthritis (OA) pain, particularly in non-weight-bearing joints like the hand (HOA), remains debated. This study assessed whether MetS is linked to increased hand pain in patients with HOA.</div></div><div><h3>Methods</h3><div>Using the DIGICOD cohort, 352 HOA patients (85 ​% women, mean age 66.4 ​± ​7.4 years) were analyzed. Pain levels were evaluated via visual analog scale (VAS), AUSCAN pain subscore, and AIMS2 pain subscore. The presence of MetS (Adult Treatment Panel III criteria) and its components were assessed alongside demographic and clinical characteristics, including BMI and radiological severity (KL sum score). Associations were adjusted for confounders (age, sex, KL score, and HAD scale). Outcomes were dichotomized into high/low pain levels, with results expressed as odds ratios (OR) and 95 ​% confidence intervals (CI).</div></div><div><h3>Results</h3><div>MetS was present in 36 ​% of patients and associated with higher pain levels during activity (VAS OR ​= ​1.61, 95 ​% CI 1.02–2.57) and overall OA pain (AIMS2 OR ​= ​1.85, 95 ​% CI 1.14–2.99). Adjusted AUSCAN pain subscore also correlated with MetS (OR ​= ​1.66, 95 ​% CI 1.05–2.62), but significance was reduced when adjusting for HAD (OR ​= ​1.56, 95 ​% CI 0.98–2.48). Elevated triglycerides, a MetS component, were significantly linked to higher AIMS2 pain scores (OR ​= ​2.58, 95 ​% CI 1.09–6.07). BMI was not found to be independently associated with pain.</div></div><div><h3>Conclusion</h3><div>MetS correlates with increased pain in HOA, independent of structural damage and anxiety/depression, underscoring its systemic impact on OA-related pain.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 1","pages":"Article 100573"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143388220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of quality indicators for hand osteoarthritis care – Results from an European consensus study","authors":"Daniel H. Bordvik ,&nbsp;Yeliz Prior ,&nbsp;Rachael Bamford ,&nbsp;Francis Berenbaum ,&nbsp;Mathilda Björk ,&nbsp;Thalita Blanck ,&nbsp;Barbara Slatkowsky Christensen ,&nbsp;Krysia Dziedzic ,&nbsp;John Edwards ,&nbsp;Nazemin Gilanliogullari ,&nbsp;Carol Graham ,&nbsp;Ida K. Haugen ,&nbsp;Margreet Kloppenburg ,&nbsp;Hellen Laheij ,&nbsp;Marco J.P.F. Ritt ,&nbsp;Tanja Stamm ,&nbsp;Anne Therese Tveter ,&nbsp;Nina Østerås ,&nbsp;Ingvild Kjeken","doi":"10.1016/j.ocarto.2025.100578","DOIUrl":"10.1016/j.ocarto.2025.100578","url":null,"abstract":"<div><h3>Background</h3><div>People with hand osteoarthritis (OA) often have poor access to recommended treatments. To enhance care quality, quality indicators (QIs) based on clinical recommendations are essential. Current QI sets, like the Osteoarthritis Quality Indicator Questionnaire (OA-QI v.2), primarily address hip- and knee OA, and not hand OA.</div></div><div><h3>Objectives</h3><div>To adapt the OA-QI v.2 for assessing patient-reported quality of hand OA care.</div></div><div><h3>Design</h3><div>We used the OA-QI v.2. set as a starting point and adapted it to reflect hand OA care. A literature search was performed to identify potential QIs for hand OA following the Rand/UCLA Appropriateness method. A European expert panel, comprising researchers, clinicians, and patient research partners, participated in online meetings to discuss adaptation and suggest new QIs based on treatment recommendations for hand OA, and anonymously rated each suggested QI regarding its importance, validity, usefulness, and feasibility. Consensus was defined by predefined rating cut-off scores. The adapted questionnaire was translated from English into Norwegian. Cognitive debriefing interviews with Norwegian and UK hand OA patients were conducted to ensure clarity.</div></div><div><h3>Results</h3><div>Our initial literature search provided 1670 articles, with none describing relevant QIs. After three voting rounds, sixteen QI items reached consensus, reflecting current hand OA care standards. Items were generally well understood, requiring only minor clarity amendments after patient interviews (N ​= ​28).</div></div><div><h3>Conclusion</h3><div>The OA-QI v.2 was successfully adapted into a 16-item Hand OA-QI set ensuring alignment with international care standards for hand OA through literature review, international expert panels and patient feedback on language and layout.</div></div>","PeriodicalId":74377,"journal":{"name":"Osteoarthritis and cartilage open","volume":"7 1","pages":"Article 100578"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}