American Journal of Men's Health最新文献_第4页

Mental Health Literacy, Stigma, and Help-Seeking Behavior Among Black Male College Students in Historically Black Universities. 传统黑人大学黑人男大学生心理健康素养、耻感与求助行为

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883251318214

Bryan Gere, Nahal Salimi

{"title":"Mental Health Literacy, Stigma, and Help-Seeking Behavior Among Black Male College Students in Historically Black Universities.","authors":"Bryan Gere, Nahal Salimi","doi":"10.1177/15579883251318214","DOIUrl":"10.1177/15579883251318214","url":null,"abstract":"Studies indicate that mental health literacy (MHL) is low among college students. Previous studies report that male college students score lower on MHL than female college students. MHL is connected to mental health help-seeking behavior. Black male college students are shown to be at higher risk for mental health problems such as depression, anxiety, and post-traumatic stress disorder, yet are less likely to seek help for these problems compared with other racial groups. Challenges with mental health can lead to significant negative consequences, such as poor academic performance, social isolation, and even suicide attempts. Stigma has been identified as an important factor that can influence the help-seeking behavior of male college students. Previous research has indicated that Black male college students in predominantly White institutions (PWIs) often struggle with seeking mental health compared with those in Historically Black Universities and Colleges (HBCUs). The purpose of the descriptive cross-sectional study was to investigate the relationships among MHL, stigma, and help-seeking behavior among Black males at HBCUs. The results indicate that having better mental health knowledge is linked to seeking help more often, stressing the need to enhance mental health understanding for better support-seeking. Seeking help was positively associated with reduced stigma. The implications for practitioners, policymakers, and administrators were explored, emphasizing the need for targeted, culturally sensitive interventions for young Black men in higher education. This study underscores the importance of addressing their specific challenges to enhance mental health and academic outcomes.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883251318214"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11848867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Clinical Effect of Acupuncture on Chronic Prostatitis: Meta Analysis. 针刺治疗慢性前列腺炎的临床疗效评价：Meta分析。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883241290035

Wen Fang, Shi Wang, Jin-Kai Dong, Jing-Yun Zhang, Xue-Chao Li, Cheng-Wei Fu, Qing-Guo Liu

{"title":"Evaluation of Clinical Effect of Acupuncture on Chronic Prostatitis: Meta Analysis.","authors":"Wen Fang, Shi Wang, Jin-Kai Dong, Jing-Yun Zhang, Xue-Chao Li, Cheng-Wei Fu, Qing-Guo Liu","doi":"10.1177/15579883241290035","DOIUrl":"10.1177/15579883241290035","url":null,"abstract":"This study aims to evaluate the clinical efficacy of acupuncture and moxibustion in CP treatment and assess the quality of clinical literature. Controlled clinical trials (CCT) and randomized controlled trials (RCTs) from PubMed, Web of Science, NLM, CNKI, and Wanfang (January 2003 to January 2023) were analyzed. Relevant data were extracted and statistically analyzed using RevMan 5.1 software. Twenty high-quality papers (JADAD≥3) involving 1,661 patients were included. Meta-analysis showed a significant difference in the overall response rate between the test and control groups in CP treatment (odds ratio [OR] = 4.08 [95% CI = 3.13, 5.33], p < .001). The National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) posttreatment comparison showed significantly better symptom improvement in the acupuncture and moxibustion group (mean difference [MD] = -4.87 [95% CI = -6.145, -3.59]). Acupuncture and moxibustion significantly improve response rates and symptom scores in CP treatment compared with control treatments (drugs, sham acupuncture). This suggests that acupuncture and moxibustion are effective for CP and worth promoting, though further exploration of their mechanisms is needed.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241290035"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11696988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Matrix Metalloproteinases and Risk of Urologic Cancers: A Bidirectional Mendelian Randomization Study. 血清基质金属蛋白酶与泌尿系统癌症的风险：一项双向孟德尔随机研究。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883241311229

BoWen Yang, XiaoYu Zeng, HanYu Wang, JiuHuan Feng, ShuFang Hou

{"title":"Serum Matrix Metalloproteinases and Risk of Urologic Cancers: A Bidirectional Mendelian Randomization Study.","authors":"BoWen Yang, XiaoYu Zeng, HanYu Wang, JiuHuan Feng, ShuFang Hou","doi":"10.1177/15579883241311229","DOIUrl":"10.1177/15579883241311229","url":null,"abstract":"Many observational epidemiological studies have reported an association between matrix metalloproteinases (MMPs) and urologic cancers. However, the causal relationship between these two phenotypes remains uncertain. This study aims to examine the bidirectional causal relationship between serum MMPs and three urologic cancers: kidney, prostate, and bladder cancer. Using data from large-scale genome-wide association studies (GWAS), we employed two-sample Mendelian randomization (MR) methods to assess the causal relationship between serum MMPs and urologic cancers. We performed inverse variance-weighted MR as the primary method for calculating the overall effects of multiple instruments, while implementing additional MR methods and sensitivity analyses. Odds ratios (ORs) were employed to evaluate the causal relationship between serum MMPs and urologic cancers risk. Our findings indicated a causal relationship between serum MMP-3 levels and prostate cancer risk (OR = 1.07, 95% confidence interval [CI] = [1.02, 1.11], p = .003). There was a possible causal relationship between serum MMP-1 and prostate cancer (OR = 0.95, 95% CI = [0.92, 0.99], p = .02). Serum MMP-1 may also increase the risk of bladder cancer (OR = 1.24, 95% CI = [1.04, 1.49], p = .016). We did not find significant associations of the remaining MMPs with prostate, bladder, and kidney cancer. In reverse MR, no significant results were observed supporting the effect of urologic cancers on MMPs (p > .05). Our study provides evidence of a potential causal relationship between serum MMPs and both prostate cancer and bladder cancer. However, large-scale studies are necessary to confirm and reveal the underlying mechanisms of this association.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241311229"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the Comfort Zone: Strenuous Sports as a Preventive Tactic Against Benign Prostatic Hyperplasia. 超越舒适区：剧烈运动作为预防良性前列腺增生的策略。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883241311209

Wei Zhang, Gang Li, Chengya Hao, Aijun Cheng

{"title":"Beyond the Comfort Zone: Strenuous Sports as a Preventive Tactic Against Benign Prostatic Hyperplasia.","authors":"Wei Zhang, Gang Li, Chengya Hao, Aijun Cheng","doi":"10.1177/15579883241311209","DOIUrl":"10.1177/15579883241311209","url":null,"abstract":"Strenuous sports are associated with an enlarged prostate. However, the genetic causality of this association remains unclear. In this study, Mendelian randomization (MR) was used to explore the potential causal relationship between strenuous sports and prostatic hypertrophy. The study utilizes single nucleotide polymorphisms (SNPs) associated with strenuous sports obtained from published genome-wide association studies (GWAS), alongside summarized genetic data related to benign prostatic hyperplasia (BPH) from published GWAS. The primary analytical method used is the Inverse Variance-Weighted (IVW) approach for two-sample MR analysis. Heterogeneity of the results is assessed using Cochran's Q-statistic, while horizontal pleiotropy is evaluated using MR-Egger. Sensitivity analyses include \"leave-one-out\" tests. The findings indicate a protective causal effect of strenuous sports on BPH (OR = 0.927, 95% CI: [0.870, 0.988]; p = .020). Results from the Weighted Median (WM) method (OR = 0.904, 95% CI: [0.837, 0.978]; p = .011) support this discovery. Using Mendelian randomization, the study provides reliable causal evidence linking high-intensity exercise to a reduced risk of BPH, overcoming biases seen in traditional observational studies. The study demonstrates a causal protective effect of strenuous sports on BPH, suggesting exercise as a preventive strategy for prostate health.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241311209"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hirudin-Based Treatment of Diabetes-Induced Erectile Dysfunction Through Inhibition of the HIF-1α to Regulate RhoA/ROCK Signaling Pathway: An In Vivo Animal Experiment. 水蛭素通过抑制HIF-1α调节RhoA/ROCK信号通路治疗糖尿病性勃起功能障碍：体内动物实验

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883241310763

Longji Sun, Nianwen Huang, Chao Yang, Junlong Feng, Hui Chen, Weidong Feng, Zixiang Gao, Bin Wang, Jisheng Wang

{"title":"Hirudin-Based Treatment of Diabetes-Induced Erectile Dysfunction Through Inhibition of the HIF-1α to Regulate RhoA/ROCK Signaling Pathway: An In Vivo Animal Experiment.","authors":"Longji Sun, Nianwen Huang, Chao Yang, Junlong Feng, Hui Chen, Weidong Feng, Zixiang Gao, Bin Wang, Jisheng Wang","doi":"10.1177/15579883241310763","DOIUrl":"10.1177/15579883241310763","url":null,"abstract":"Diabetes-induced erectile dysfunction (DIED) is a type of refractory erectile dysfunction which can be clinically treated using the traditional Chinese medicine leech whose main ingredient is hirudin. Oxidative stress can damage vascular endothelial cells, affect blood circulation, and induce fibrosis of smooth muscle cells. This study assessed the efficacy of hirudin in treating DIED before exploring its potential mechanism of action. DIED was induced in rats using streptozotocin, while experimental apomorphine was used to screen for erectile dysfunction models. The rats were then divided into four groups: a blank control group (NC group), a model group (M group), a hirudin group (H group), and an inhibitor group (YC group). After 2 weeks, the serum levels of malondialdehyde (MDA), superoxide dismutase (SOD), and nitric oxide (NO) were determined. The histological features and HIF-1α/RhoA/ROCK signaling pathway-related proteins of the penile corpus cavernosum were detected. Erectile function improved in the H and YC groups without significantly affecting body weight and blood glucose levels, with histopathological analysis also showing improvement in penile structure in these groups. In addition, the expression of HIF-1α/RhoA/ROCK signaling pathway-related proteins was lower in the penile cavernous tissue of rats in the H and YC groups (p < .05), with the serum levels of NO and SOD also being higher in these groups (p < .05). The serum level of MDA decreased in the YC and H groups (p < .05). In this study, only animal experiments were conducted to investigate the regulation of Rho/ROCK pathway by HIF-1α. Cellular studies of the underlying mechanisms are lacking.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241310763"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11815967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can We Predict the Outcome of Micro Testicular Sperm Extraction in Non-Obstructive Azoospermia From Preoperative Hormonal Profile, Testicular Volume, and Patients Health Factors: A Retrospective Cross-Sectional Study. 我们能否从术前激素水平、睾丸体积和患者健康因素预测非阻塞性无精子症患者微睾丸精子提取的结果：一项回顾性横断面研究。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883251320017

Mohammad Al-Zubi, Sawsan Al-Khawaldeh, Mos'ab Mallak, Muthanna Al-Dghaim, Raneem Zytoon, Rahaf Abbas, Ahmad Alhabahbeh, Marah Alfadel, Saleh Abuorouq, Mohammad Radhi Al-Magableh, Ahmed Nemer Alkhateeb, Mosab Radwan Alboon, Saddam Al Demour, Samer Fathi Al-Rawashdah

{"title":"Can We Predict the Outcome of Micro Testicular Sperm Extraction in Non-Obstructive Azoospermia From Preoperative Hormonal Profile, Testicular Volume, and Patients Health Factors: A Retrospective Cross-Sectional Study.","authors":"Mohammad Al-Zubi, Sawsan Al-Khawaldeh, Mos'ab Mallak, Muthanna Al-Dghaim, Raneem Zytoon, Rahaf Abbas, Ahmad Alhabahbeh, Marah Alfadel, Saleh Abuorouq, Mohammad Radhi Al-Magableh, Ahmed Nemer Alkhateeb, Mosab Radwan Alboon, Saddam Al Demour, Samer Fathi Al-Rawashdah","doi":"10.1177/15579883251320017","DOIUrl":"10.1177/15579883251320017","url":null,"abstract":"Infertility is characterized by the inability to conceive even after engaging in regular unprotected sexual intercourse for a period of 12 months or longer. Azoospermia affects around 1% of men. Approximately 60% of men diagnosed with azoospermia will have non-obstructive azoospermia (NOA). The main aim of this study is to investigate the potential relationship between preoperative hormonal profiles, testicular volume, and patient health factors with microdissection testicular sperm extraction (micro-TESE) outcomes in individuals with NOA. A retrospective analysis of 152 patients who underwent a micro-TESE operation for NOA at our center from January 2020 to December 2022 was conducted. Both groups were compared for age, follicle-stimulating hormone (FSH), luteinizing hormone (LH), total and free testosterone, testicular volume before the operation, previous TESE, smoking, and medical illnesses. A relationship is considered significant when the p value is less than .05. A total of 152 NOA patients were enrolled in this study. Patients were divided into two groups: first group, in whom sperms were identified during the procedure, representing 72 (47.3%) of patients, and the second group (52.7%) of patients, in whom no sperms were found. Results reveal that free testosterone level, total testosterone level, smoking, and previous TESE operation are significantly related to positive surgical results (p value < .05). Our findings suggest that preoperative total and free testosterone levels, smoking status, and previous micro-TESE operation may significantly affect the outcomes of micro-TESE.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883251320017"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11848872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cyclosporine A Decreased Paclitaxel Resistance in Prostate Cancer Cells by Inhibiting MTDH Expression. 环孢素A通过抑制MTDH表达降低前列腺癌细胞紫杉醇耐药。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883241310834

Jiangtao Li, Yuzhi Li, Xiaohong Zhang, Kun Liu, Shiping Yang, Zhang Liu, Sheng Cao, Dongfei Ren, Menghui Cui, Jia Su, Zewang Zhen, Donghong Zhang

{"title":"Cyclosporine A Decreased Paclitaxel Resistance in Prostate Cancer Cells by Inhibiting MTDH Expression.","authors":"Jiangtao Li, Yuzhi Li, Xiaohong Zhang, Kun Liu, Shiping Yang, Zhang Liu, Sheng Cao, Dongfei Ren, Menghui Cui, Jia Su, Zewang Zhen, Donghong Zhang","doi":"10.1177/15579883241310834","DOIUrl":"10.1177/15579883241310834","url":null,"abstract":"This study aims to investigate the effect and mechanism of cyclosporine A (CsA) on paclitaxel-resistant prostate cancer cells. Paclitaxel-resistant prostate cancer cell lines were established by gradual increment method. The proliferation of cells was tested using MTT and colony formation assay. Western blot was used to detect protein expression. Expression levels of gene mRNA were detected using real-time polymerase chain reaction (RT-PCR). Xenografts in nude mice were used to validate the conclusion in vitro. The results showed that CsA could increase the sensitivity of prostate cancer cells to paclitaxel. Treatment of paclitaxel-resistant prostate cancer cell lines with CsA gradients decreased metadherin (MTDH) protein expression. RT-PCR showed that CsA could decrease the mRNA level of MTDH. Overexpression of MTDH in prostate cancer cells increases paclitaxel resistance in prostate cancer cells. Conversely, knockdown of MTDH reduced paclitaxel resistance in prostate cancer cells. Treating cells with CsA failed to reduce paclitaxel resistance in prostate cancer cells when MTDH was overexpressed. Xenografts in nude mice yielded consistent conclusions with the in vitro results. In conclusion, CsA can reduce the resistance of prostate cancer cells to paclitaxel. In vitro and in vivo experiments have shown that CsA can reduce paclitaxel resistance in prostate cancer cells by decreasing MTDH expression. In clinical practice, CsA can be used in combination with paclitaxel to improve the therapeutic effect on prostate cancer. MTDH may serve as a novel target for treating paclitaxel resistance in prostate cancer.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241310834"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thanks to Reviewers. 感谢评论者。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883251322307

引用次数: 0

Modulation of NLRP3 Inflammasome Activation by QYHT Decoction: Implications for the Treatment of Erectile Dysfunction in Hyperuricemia. 芪黄酮汤对NLRP3炎性体激活的调节：对高尿酸血症患者勃起功能障碍的治疗意义。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883251318307

Pingyu Ge, Yinxue Guo, Bangwei Che, Hang Jin, Lan Chen, Zhichao Chen, Kaifa Tang

{"title":"Modulation of NLRP3 Inflammasome Activation by QYHT Decoction: Implications for the Treatment of Erectile Dysfunction in Hyperuricemia.","authors":"Pingyu Ge, Yinxue Guo, Bangwei Che, Hang Jin, Lan Chen, Zhichao Chen, Kaifa Tang","doi":"10.1177/15579883251318307","DOIUrl":"10.1177/15579883251318307","url":null,"abstract":"Hyperuricemia (HUA) causes vascular endothelial dysfunction and oxidative stress, and simultaneously activates the NLRP3 inflammasome, leading to inflammatory reactions and erectile dysfunction (ED). This study aimed to investigate the effects of QYHT (Quyuhuatanerxian decoction) decoction on the NLRP3 inflammasome and explore its potential in treating HUA-induced ED. This study employed four treatment methods: (a) treating HUA-induced ED patients with QYHT and analyzing changes in gut microbiota abundance and fecal metabolites through 16S sequencing; (b) establishing an HUA-induced ED rat model, treating with different doses of QYHT, and examining changes in serum metabolites; (c) conducting fecal microbiota transplantation (FMT) therapy; evaluating erectile function, oxidative stress, inflammatory response, and NLRP3 inflammasome activation levels; and (d) exploring key monomeric compounds and potential targets in QYHT through network pharmacology and molecular docking. The treatment with QYHT and FMT increased testosterone levels, reduced oxidative stress and inflammatory marker levels, and inhibited the expressions of NLRP3-related factors. QYHT affected the gut microbiota structure and metabolite levels. The key components were linoleoyl acetate and mandanol, and the target was JAK2. QYHT decoction regulates the distribution of gut microbiota, improves amino acid metabolism, and effectively inhibits the activation of NLRP3 inflammasomes. This, in turn, enhances erectile function and reduces oxidative stress and inflammatory response levels, leading to successful treatment of HUA-induced ED.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883251318307"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relative Fat Mass, A Better Predictor of Erectile Dysfunction: Insights From the NHANES 2001-2004. 相对脂肪量，一个更好的预测勃起功能障碍：来自NHANES 2001-2004的见解。

IF 2.1 4区医学

American Journal of Men's Health Pub Date : 2025-01-01 DOI: 10.1177/15579883241311218

BoWen Yang, HanYu Wang, Luyi Tang, JiuHuan Feng, ShuFang Hou

{"title":"Relative Fat Mass, A Better Predictor of Erectile Dysfunction: Insights From the NHANES 2001-2004.","authors":"BoWen Yang, HanYu Wang, Luyi Tang, JiuHuan Feng, ShuFang Hou","doi":"10.1177/15579883241311218","DOIUrl":"10.1177/15579883241311218","url":null,"abstract":"Obesity is a significant factor contributing to erectile dysfunction (ED). Early detection of ED generally results in improved treatment outcomes. Our study aims to elucidate the association between relative fat mass (RFM) and ED by analyzing data from the National Health and Nutrition Inspection Survey (NHANES) spanning 2001 to 2004. We used data from NHANES 2001-2004, employing weighted, multivariable-adjusted logistic regression to assess the relationship between RFM and the risk of ED. Additional analyses included subgroup analysis, smooth curve fitting, and threshold effect analysis. Subsequently, the predictive utility of RFM, body mass index (BMI), and waist circumference (WC) for ED was evaluated using the receiver operating characteristic curve and area under the curve (AUC) calculations. A total of 3,947 American male participants were included in this retrospective study within NHANES. Weighted multivariate logistic regression analysis indicated that, after adjusting for potential confounding factors, RFM was positively associated with the risk of ED (OR = 1.03, 95% CI = 1.01-1.05, p < .001). No significant saturation effects between RFM and ED were observed (all ps > .05). In addition, RFM demonstrated superior predictive capability for ED (AUC = 0.644) compared with BMI (AUC = 0.525) and WC (AUC = 0.612). Our findings suggest that higher RFM levels are associated with an increased risk of ED, highlighting its potential utility as a predictive marker for this condition.","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 1","pages":"15579883241311218"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0