American Journal of Men's Health最新文献

{"title":"Sex-Specific Clinical Characteristics and Mortality Predictors in Patients With Usual Interstitial Pneumonia Pattern: A Retrospective Cohort Study Highlighting Male Health Risks.","authors":"Suat Konuk, Alp Ozel, Emine Ozsari, Sena Melis Sert","doi":"10.1177/15579883251397902","DOIUrl":"10.1177/15579883251397902","url":null,"abstract":"<p><p>Usual Interstitial Pneumonia (UIP) is a progressive fibrotic lung condition most commonly observed in older men, yet sex-specific clinical outcomes remain underexplored. This retrospective cohort study aimed to examine demographic, clinical, radiological, and mortality-related characteristics of patients diagnosed with a UIP pattern based on high-resolution computed tomography (HRCT), using real-world data from a tertiary chest clinic in Turkey between 2015 and 2025. A total of 100 patients were included, of whom 72% were male. The mean age was 68.4 years, and the average smoking burden was 32.5 pack-years. Radiological progression occurred in 48% of cases, and overall mortality was 26%. Malignancy was an independent predictor of mortality (adjusted odds ratio [OR] = 2.85, 95% confidence interval [CI]: [1.10, 7.43]; <i>p</i> = .032), alongside older age (per year: adjusted OR = 1.06, 95% CI = [1.01, 1.12]; <i>p</i> = .041). Despite the high smoking prevalence, no significant association was found between smoking load and mortality. These findings underscore the disproportionate burden of UIP among older men and highlight the importance of routine malignancy screening and individualized follow-up strategies in this population. The study supports the integration of interstitial lung disease surveillance into comprehensive men's health care frameworks and calls for increased awareness of UIP's clinical implications in at-risk male populations.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251397902"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12686373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145699556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional Evaluation of Vascular Dysfunction in Diabetic Erectile Dysfunction: Synergistic Application of ICP Measurement, Laser Speckle Blood Perfusion Imaging, and Ex Vivo Microvascular Tension Measurement.","authors":"Siyi Pan, Huangfu Ma, Zhongliao Zeng, Jingwei Wang, Jie Huang, Jianxiong Ma","doi":"10.1177/15579883251394309","DOIUrl":"10.1177/15579883251394309","url":null,"abstract":"<p><p>Diabetic erectile dysfunction (DMED) is a complex condition primarily characterized by impaired vasodilation and inadequate blood perfusion. As of 2023, the available techniques for evaluating vascular function are limited. Intracavernous pressure (ICP) measurement is regarded as the gold standard for assessing erectile function in animals, yet this approach struggles to differentiate between vascular endothelial dysfunction and smooth muscle dysfunction. This study assessed erectile function in DMED rats and analyzed the hemorheology of the penile corpus cavernosum in conjunction with laser speckle blood perfusion imaging (LSBPI). The vasomotor function of the internal iliac artery (IIA) was evaluated using ex vivo microvascular tension measurement. Masson staining was applied to investigate structural alterations in the IIA and cavernous arteries, and immunofluorescence was utilized to measure the protein expression levels of vascular cell adhesion molecule (VCAM), vascular endothelial growth factor (VEGF), and endothelial nitric oxide synthase (eNOS), revealing vascular functional status at both tissue and molecular levels. The model group showed lower ICP values, diminished blood flow, and reduced vasoconstrictive capacity compared to the control group. High-potassium stimulation caused a more pronounced decrease in vascular tension in the model group. Sodium nitroprusside produced comparable vasodilatory responses in both groups; following incubation with N-nitro-L-arginine methyl ester, the model group demonstrated decreased vascular tension. The model group exhibited fibrosis in penile tissue, elevated levels of VCAM-1 and VEGF, and decreased expression of eNOS protein. The integration of ICP with LSBPI and vascular tensiometry enables simultaneous in vivo hemodynamic monitoring and ex vivo functional dissection of endothelial-smooth muscle interactions in DMED.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251394309"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12686376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145699454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative Study of Men's Experiences of Becoming a Father for the First-Time in Pakistan: A Critical Realist Perspective.","authors":"Sadaf Zindani, Julie Chartrand, Jean Hannan, J Craig Phillips","doi":"10.1177/15579883251396539","DOIUrl":"10.1177/15579883251396539","url":null,"abstract":"<p><p>There is a knowledge gap about fathers' experiences during the perinatal period globally. Limited literature addresses experiences of first-time fathers during the perinatal period in the sociocultural context of Pakistan. This is the first study to explore the experiences of first-time fathers during the perinatal period in Pakistan and seeks to clarify those experiences from the father's perspectives. Critical realism (CR) philosophy was integrated with the socioecological model (SEM) framework to guide this qualitative descriptive study. Eight first-time fathers were recruited and interviewed individually at their homes by male research assistants. Four fathers were experiencing the prenatal phase and four were experiencing the postnatal phase up to 6 months after delivery. Interview data were analyzed using inductive content analysis technique. Results revealed the multifaceted relationship between agents and social structures in contributing to the perinatal experiences of first-time fathers in Pakistan. Religion played a strong role in shaping first-time Pakistani fathers' experiences in both prenatal and postnatal phases of the perinatal period. Economic conditions in Pakistan contributed to fathers' stress about providing for family expenses and their child's future. Hospital and government policies were a major concern for postnatal fathers. All fathers developed a sense of responsibility after receiving news about becoming a father. Integration of CR and SEM facilitated new insights. This multilevel perspective may offer hope for improving the experiences of first-time fathers during their wives' perinatal period. These new insights can also assist policymakers and researchers in developing strategies and interventions for successful transition to fatherhood in Pakistan.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251396539"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12665812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mendelian Randomization Analyses Support Causal Relationships Between Psychiatric Disorders and Risk of Urinary Tract Infections.","authors":"Minghui Ke, Haolang Wen, Binghao Bao, Yuan Liu, Lei Zhang, Chenglong Zheng, Baoxing Liu","doi":"10.1177/15579883251400693","DOIUrl":"10.1177/15579883251400693","url":null,"abstract":"<p><p>Observational studies have identified a significant co-morbidity between urinary tract infections (UTIs) and psychiatric disorders, yet the causal relationship remains uncertain. We conducted a bidirectional Mendelian randomization (MR) analysis to evaluate the causal relationship between psychiatric disorders (schizophrenia [SC], bipolar disorder [BD], major depressive disorder [MDD], autism spectrum disorder [ASD], attention-deficit/hyperactivity disorder [ADHD], obsessive-compulsive disorder [OCD], anorexia nervosa [AN]) and UTIs using data from the Psychiatric Genomics Consortium and UK Biobank. To account for potential confounding factors and investigate the independent effects of multiple psychiatric disorders, we further employed multivariable Mendelian randomization (MVMR). Inverse variance weighted analysis demonstrated that genetic susceptibilities of MDD and ASD increased UTI risk with odds ratios (ORs) of 1.31 (95% CI: 1.15-1.48, <i>p</i> < .001) and 1.08 (95% CI: 1.03-1.15, <i>p</i> = .004), respectively. UTIs were associated with a slight increase in the risk of MDD, evidenced by an OR of 1.061 (95% CI: 1.01-1.12, <i>p</i> = .019). Multivariate MR analysis revealed that MDD, after adjusting for type 2 diabetes mellitus and urinary stones, increased UTI risk (OR = 1.25, 95% CI: 1.08-1.45, <i>p</i> = .002), with smoking mediating 13.6% (<i>p</i> = .006) of MDD's effect on UTIs. Our study establishes a causal relationship between psychiatric disorders and UTIs, identifying smoking as a mediator. These findings provide valuable guidance for clinicians to develop effective prevention and management strategies for patients with coexisting mental disorders and UTIs.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251400693"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12686375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145699495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Study of Changes in Fertility Awareness and Lifestyle Behaviors Among Men in Japan After Viewing an Educational Video Focused on Enhancing Sperm Quality.","authors":"Kaori Nakada-Nakagomi, Fumi Atogami","doi":"10.1177/15579883251394806","DOIUrl":"10.1177/15579883251394806","url":null,"abstract":"<p><p>Lifestyle factors greatly affect fertility, making improving the fertility awareness of men an urgent matter. This study aimed to assess changes in fertility awareness and lifestyle behaviors among men after viewing a video focusing on sperm quality. The participants in this single-group, longitudinal study were employed men in their 20s and 30s without children. They were administered an online questionnaire survey three times: before, immediately after, and 2 weeks after viewing the video. This study was conducted in January 2024 after undergoing institutional ethics review. A total of 69 participants were included in the analysis. The results indicated that the proportion of participants interested in fertility after viewing the video increased significantly, from 44.9% (<i>n</i> = 31) to 76.8% (<i>n</i> = 53; <i>p</i> < .001). Of the 13 lifestyle behaviors covered in the survey, a significant difference was seen for only one after 2 weeks: walking for approximately 5 min after sitting for approximately 1 hr (<i>p</i> = .035). The percentage of participants whose awareness of improvements in their lifestyle behavior had changed 2 weeks after viewing the video ranged from 19.1% to 39.1% lower for all 13 items. The change in awareness of each lifestyle behavior was analyzed based on participants who had already regularly engaged in the behavior and participants who had not, and significant differences were seen for seven behaviors. These results indicate that the video was effective for stimulating men's interest in their own fertility. However, challenges remain in changing lifestyle behaviors.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251394806"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12686378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145699460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV Prevention in Men: A Narrative Review of Strategies, Risks, and Public Health Implications.","authors":"Martin S Lipsky, Bayler Gunnell, Justin Nguyen, Samantha Lee, Geo Wolfe, Man Hung","doi":"10.1177/15579883251391750","DOIUrl":"10.1177/15579883251391750","url":null,"abstract":"<p><p>Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide, impacting both males and females. In men, HPV causes genital warts, more than 90% of anal cancers, and 60% of oropharyngeal cancers. Given that one in three men are infected with HPV worldwide, there is a pressing need for enhanced public health strategies focusing on prevention. This comprehensive narrative review presents an overview of HPV in men, key risk factors, and primary prevention in men. The most effective preventive measure for HPV in males is vaccination. Males at high risk for HPV include those who smoke, have human immunodeficiency virus, consume alcohol, engage with multiple sexual partners, fail to use barrier methods, and are unvaccinated. HPV vaccinations prevent most HPV-associated diseases; however, numerous barriers to vaccine uptake remain, including misconceptions that men do not benefit from vaccination, safety concerns, limited accessibility, and inconsistent vaccine recommendations.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251391750"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12638683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145556057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>\"I'm a Work in Progress\"</i>: Rethinking Posttraumatic Growth Among Low-Income Black Men.","authors":"Cherrell Green, Melissa E Noel","doi":"10.1177/15579883251408383","DOIUrl":"10.1177/15579883251408383","url":null,"abstract":"<p><p>Low-income Black men in the United States experience cumulative trauma shaped by structural violence, including poverty, residential segregation, over-policing, mass incarceration, and community violence. These systemic harms disrupt identity, relationships, and opportunity, constraining both exposure to trauma and pathways for recovery and growth. Drawing on Tedeschi and Calhoun's posttraumatic growth (PTG) framework, integrated with socioecological and culturally grounded perspectives on resilience, this study examines how low-income Black men make meaning of trauma and pursue transformation amid structural constraints. Using in-depth qualitative case studies with 10 men, we highlight four focal cases to illustrate diverse trajectories of growth. Findings show that PTG unfolds as an iterative, contextually embedded process: some men achieved comprehensive transformation through prosocial engagement, fatherhood, and relational repair, whereas others navigated persistent structural barriers yet demonstrated growth through survival, persistence, and redefined purpose. By situating PTG within systemic inequality, relational networks, and cultural context, this study extends the framework beyond individual cognition, emphasizing how structurally and socially mediated pathways shape PTG among marginalized Black men.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251408383"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12717393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145779793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black Men's Prostate Cancer Knowledge, Attitudes, Beliefs, and Access to Health Information.","authors":"Linda Mermelstein, Jackelyn B Payne, Rose Martillotti, K Olivia Mock, Anne E Moyer, Linda Bily, Giuseppina Caravella, Jaclyn M Grimaldi, Yuri T Jadotte, Jedan P Phillips, Kathleen H Scarbrough, Jenna Francois, Barbara D Nemesure","doi":"10.1177/15579883251377306","DOIUrl":"10.1177/15579883251377306","url":null,"abstract":"<p><p>Disparities in prostate cancer incidence and mortality among Black men exist in Suffolk County, New York, indicating a need to provide effective educational interventions about prostate cancer screening for this population. We conducted a mixed-methods study exploring Black men's knowledge, attitudes, and beliefs about prostate cancer, and how they access health information. Three semi-structured virtual focus groups were conducted by Black male physicians with 18 Black men aged 40 years and over living in Suffolk County, New York. All were recorded, transcribed, and coded to identify key themes. Participants also completed surveys assessing prostate cancer knowledge and information preferences. Quantitative and qualitative results were analyzed using SPSS and NVivo software. Recruitment required extensive outreach. Even among relatively well-educated participants, more prostate cancer knowledge was needed, and 11% had not obtained screening because they were not aware they needed it. Family history prompted prostate cancer concerns, and fear of dying from prostate cancer motivated screening. Health information from reputable website sources was preferred, with social media drawing attention to educational opportunities and education portraying individuals to whom Black men could relate. Participants expressed desire for further engagement between their community, the academic hospital, and physicians. Our results indicated that despite being relatively knowledgeable about prostate cancer, Black men desire stronger ties and trust between their community and health care providers to facilitate screening. These data may assist health care professionals in designing practical educational tools and tailored programs about prostate cancer screening among Black men who are at increased risk of disease.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251377306"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12592645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Restorative Masculine Integration Theory.","authors":"Todd Angelucci, Julian L Gallegos","doi":"10.1177/15579883251391763","DOIUrl":"10.1177/15579883251391763","url":null,"abstract":"<p><p>The Restorative Masculine Integration Theory (RMIT) introduces a strengths-based, systems-oriented framework for promoting healthy masculinity through healing, leadership, and relational engagement. Developed in response to the adverse effects of masculine suppression, such as emotional disengagement, burnout, and polarity collapse, RMIT outlines a five-phase Cycle of Masculine Restoration: reclaimed masculinity, emotional safety and trust, grounded leadership, rebalanced gender polarity, and healing with cultural renewal. These stages are underpinned by core concepts including psychological safety, peer mentorship, emotional literacy, and authentic masculinity. Drawing from interdisciplinary foundations in gender studies, emotional intelligence, trauma-informed practice, polarity theory, and servant leadership, RMIT offers an adaptable framework for use across clinical, educational, organizational, and policy settings. Its alignment with the MANifest Health Theory further strengthens its applicability in men's health promotion. This manuscript elaborates the theory's conceptual development, visual model, and practical implications, while identifying future directions for empirical validation and inclusive application. RMIT advances a timely and restorative model for transforming masculine identity into a source of individual and collective resilience.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 6","pages":"15579883251391763"},"PeriodicalIF":2.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12665813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145627496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"No Evidence of Temporal Decline in Semen Parameters Over 17 Years Among Men Who Underwent Fertility Evaluation from Indian Southern States.","authors":"Huidrom Yaiphaba Meitei, Nithyashree Kadiregowda, Dhakshanya Predheepan, Vani R Lakshmi, Shubhashree Uppangala, Padmaraj Hegde, Guruprasad Kalthur, Stefan Schlatt, Satish Kumar Adiga","doi":"10.1177/15579883251383438","DOIUrl":"10.1177/15579883251383438","url":null,"abstract":"<p><p>Over the past four decades, reports have emphasized the spatial and temporal trends in human semen quality and other markers of male reproductive health, which have sparked significant debate among fertility professionals. This trend appears limited to specific geographical regions rather than being global. The study aimed to retrospectively review the comprehensive distribution of semen characteristics and analyze their temporal changes over a period of 17 years at a single center in the southern parts of India. Ejaculates of 12,151 sub-fertile men undergoing infertility workup at the University Andrology Laboratory from 2006 to 2022 were included. Semen analysis was performed as per the World Health Organization (WHO, 1999, 2010) recommendations. The primary outcome of interest was temporal changes in semen parameters, whereas data regarding the distribution of semen characteristics were also measured. Sperm concentration, total sperm number, motility, vitality, and morphology showed no significant variations over time. The fifth percentile of semen volume, sperm concentration, total motility, vitality, and normal morphology were 0.5 mL, 1.5 million/mL, 21.0%, 28.0%, and 7.0%, respectively. This study revealed no temporal decline in sperm concentration, motility, and morphology in 17 years, and found fifth percentile sperm characteristics were lower than WHO reference values, marking the extensive long-term semen quality analysis from a single Indian laboratory. The findings reported here do not support an alarming temporal decline in semen quality.</p>","PeriodicalId":7429,"journal":{"name":"American Journal of Men's Health","volume":"19 5","pages":"15579883251383438"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12553896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145336021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}