Neuroimage. Reports最新文献

{"title":"Teaching-induced changes in neural networks: Toward a model of the creative universe","authors":"Camilo J. Cela-Conde ,&nbsp;Sara Lumbreras ,&nbsp;Sandra Pusil ,&nbsp;Brenda Chino ,&nbsp;José M. Caamaño ,&nbsp;Laura Gismera ,&nbsp;Fernando Maestú ,&nbsp;Luis Rojas-Marcos","doi":"10.1016/j.ynirp.2025.100280","DOIUrl":"10.1016/j.ynirp.2025.100280","url":null,"abstract":"<div><div>According to the standard definition, a creative act requires originality and effectiveness. Creativity is widely considered an exclusively human characteristic, linked to the activity of brain networks such as the Default Mode Network (DMN), the Fronto-Parietal Network (FPN), and, to a lesser extent, the Salience Network (SN). A significant body of literature explores the viability of teaching creativity, often reporting positive results. However, little attention has been paid to the neural network modifications induced by creativity training.</div><div>This study investigates changes of creativity-related brain networks over time in the resting state (participants without specific cognitive activities). The stages considered were before and after a learning process focused on visual aesthetic creation tasks (Gabarron Method). High-density electroencephalography (EEG) was used to record brain activity. 51 female volunteers participated in the research.</div><div>The results show a significant increase in the activation of the DMN and FPN, with a more limited effect in the SN. The DMN and FPN are neural networks commonly activated during artistic creation and aesthetic perception tasks. This finding supports the existence of what could be called a 'creative universe,' encompassing capacities such as creation, perception, and divergent thinking.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100280"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling trauma memory: Differential functional connectivity profiles of anterior and posterior hippocampus in post-traumatic stress disorder and its dissociative subtype","authors":"Mohammad Chaposhloo ,&nbsp;Margaret C. McKinnon ,&nbsp;Breanne E. Kearney ,&nbsp;Saurabh B. Shaw ,&nbsp;Ruth Lanius ,&nbsp;Suzanna Becker","doi":"10.1016/j.ynirp.2025.100279","DOIUrl":"10.1016/j.ynirp.2025.100279","url":null,"abstract":"<div><div>Post-traumatic stress disorder (PTSD) has long been viewed by many as a disorder of memory. Consequently, the hippocampal brain networks have been an important focus of research on the neural circuitry of PTSD given its core involvement in episodic memory and mechanisms underlying traumatic memory. The primate hippocampus is functionally divided along its long axis into the anterior (aHipp) and posterior parts (pHipp), with the anterior portion playing a greater role in emotion-related memories, while the posterior region is more involved in cognitive and spatial processing. This suggests that the aHipp may be more actively involved in PTSD. Critically, however, little research has investigated the differential involvement of these hippocampal subregions in PTSD, and most research in this area has been conducted during rest rather than during the active recall of traumatic or extremely emotional memories. It is an open question whether anterior and posterior hippocampal regions might play differential roles during trauma-related memory recall. Here, we addressed this question by investigating the activity and the whole-brain functional connectivity of the aHipp and pHipp during the recall of traumatic/moral injury (MI) related trauma memories versus neutral memories in three groups: those with PTSD without dissociative symptoms, referred to as PTSD (DS-; n = 49), those with the dissociative subtype, referred to as PTSD (DS+; n = 19), and trauma-exposed healthy controls (n = 36). Both anterior and posterior hippocampal subregions displayed abnormal functional connectivity with various brain regions in PTSD (DS+) during trauma memory recall, with the pHipp showing more extensive abnormalities compared to the anterior part. For example, the pHipp showed abnormal functional connectivity with areas such as the anterior cerebellum, the parahippocampal and fusiform gyri, sensorimotor cortex, and early visual areas of the occipital lobe in PTSD (DS+) compared to PTSD (DS-) and controls during the recall of traumatic/MI memories. Collectively, these results suggest differential involvement of the anterior and posterior hippocampus in the recall of traumatic memories in traumatic/MI-related PTSD and its dissociative subtype, which may relate to the decontextualized and fragmented nature of traumatic memories.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100279"},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-CBT resting-state connectivity and white matter integrity in OCD remission: A multimodal MRI study","authors":"Yuki Ikemizu ,&nbsp;Yuko Isobe ,&nbsp;Yusuke Sudo ,&nbsp;Junko Ota ,&nbsp;Ritu Bhusal Chhatkuli ,&nbsp;Tubasa Sasaki ,&nbsp;Kohei Kurita ,&nbsp;Tokiko Yoshida ,&nbsp;Koji Matsumoto ,&nbsp;Masaru Kuno ,&nbsp;Naoko Kato ,&nbsp;Akiko Nakagawa ,&nbsp;Eiji Shimizu ,&nbsp;Yoshiyuki Hirano","doi":"10.1016/j.ynirp.2025.100275","DOIUrl":"10.1016/j.ynirp.2025.100275","url":null,"abstract":"<div><h3>Background</h3><div>Obsessive-compulsive disorder (OCD) is commonly treated with cognitive-behavioral therapy (CBT), yet many patients fail to achieve remission. Neuroimaging markers, such as pre-treatment functional and structural connectivity, may help elucidate OCD pathology and CBT mechanisms, and predict treatment outcomes. This study investigates the relationship between pre-treatment functional and structural connectivity and remission status in OCD patients following CBT.</div></div><div><h3>Methods</h3><div>Thirty-three OCD patients underwent multimodal MRI, including resting-state fMRI to assess pre-treatment functional connectivity and diffusion tensor imaging (DTI) to evaluate white matter integrity. Functional connectivity multivariate pattern analysis (fc-MVPA) identified patterns linked to treatment outcomes. TRACULA, a probabilistic tractography technique, analyzed white matter tracts, focusing on diffusion metrics such as fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (AD). Analysis of covariance (ANCOVA) was used to examine group differences.</div></div><div><h3>Results</h3><div>Remission was associated with significantly higher pre-treatment resting-state functional connectivity between the occipital pole and lateral occipital cortex (height threshold: p &lt; 0.001 uncorrected and cluster threshold: p &lt; 0.05 cluster-size FDR corrected for multiple comparisons), suggesting a role in visual processing. Differences in white matter integrity were found in the corpus callosum rostrum, left acoustic radiation, right dorsal cingulum bundle, and right superior longitudinal fasciculus II, though these results were not corrected for multiple comparisons.</div></div><div><h3>Conclusion</h3><div>Enhanced pre-treatment functional connectivity in visual processing regions and specific white matter tracts may serve as biomarkers for remission in OCD following CBT. These findings could improve understanding of CBT’s neural effects and guide personalized treatment strategies.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100275"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor and default mode network states of rest in frontal lobe epilepsy","authors":"Tahereh Rashnavadi ,&nbsp;Raphael F. Casseb ,&nbsp;Kristine E. Woodward ,&nbsp;Paolo Federico ,&nbsp;Bradley Goodyear","doi":"10.1016/j.ynirp.2025.100278","DOIUrl":"10.1016/j.ynirp.2025.100278","url":null,"abstract":"<div><div>Frontal lobe epilepsy (FLE), marked by recurrent seizures arising from the frontal lobes, can significantly impair cognitive and motor function, reducing quality of life. Recent studies suggest that epilepsies can involve functional networks throughout the brain that can be identified using resting-state functional magnetic resonance imaging (fMRI). In this study, we aimed to determine whether FLE is associated with a distinct functional network brain states. Using dynamic functional connectivity analysis in combination with <em>k</em>-means clustering, we investigated dynamic connectivity patterns of the somatomotor network (SMN) and default mode network (DMN) of ten right-hemisphere and six left-hemisphere FLE patients, as well as nine healthy controls. We found two distinct states of rest for both the SMN and DMN: a high connectivity state and a lower, more variable connectivity state that was often specific to individual patients. Both FLE groups showed reduced overall connectivity compared to controls, with the greatest differences emerging during the low connectivity state. Right FLE patients and controls exhibited relatively uniform reductions, whereas left FLE patients showed spatially specific disruptions, including reduced lateral-to-medial SMN connectivity and decreased connectivity in posterior and left-lateralized DMN regions. Our findings suggest that dynamic connectivity analysis can uncover the temporal complexity and patient-specific nature of brain network disruption in FLE, supporting the development of personalized diagnostic and treatment strategies. Further research with larger cohorts is necessary to validate these results and explore additional factors affecting brain functional connectivity.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100278"},"PeriodicalIF":0.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural and effective brain connectivity in focal epilepsy","authors":"S.B. Jelsma ,&nbsp;M. Zijlmans ,&nbsp;I.B. Heijink ,&nbsp;F.W.A. Hoefnagels ,&nbsp;M. Raemaekers ,&nbsp;W.M. Otte ,&nbsp;N.E.C. van Klink ,&nbsp;D. van Blooijs","doi":"10.1016/j.ynirp.2025.100274","DOIUrl":"10.1016/j.ynirp.2025.100274","url":null,"abstract":"<div><div>Epilepsy surgery is usually based on the removal of a local epileptogenic zone. If epilepsy is considered a network disease, a network approach might be more suitable. Insight into patient-specific epileptic brain networks is necessary to establish network-based surgical strategies.</div><div>We included epilepsy surgery candidates who underwent diffusion-weighted imaging and intracranial EEG implantation with single pulse electrical stimulation (SPES, 0.2 Hz, 1–8 mA, 1 ms, monophasic stimuli) during presurgical evaluation. We reconstructed structural connectivity using fiber tractography taking intracranial electrodes as nodes. We reconstructed effective connectivity with SPES cortico-cortical evoked responses. We determined the inter-modal similarity between structural and effective connectivity with the Jaccard index, and compared network topologies using degree and betweenness centrality. We constructed a linear multilevel model to evaluate the relation between structural and effective connectivity at subject group level. The seizure onset zone nodes (SOZ), node proximity, and the volume of the electrode contact areas (VEA) were added to the model as possible predictors to accommodate for epilepsy and irregular spatial sampling.</div><div>We included 13 patients (five with electrocorticography, eight with stereo-EEG). The median Jaccard index was 0.25 (IQR: 0.20–0.29), which means there is a higher overlap than expected by chance (median expected Jaccard index = 0.1 (IQR: 0.07–0.17)) with a considerable amount of connections that did not overlap. The structural connectivity degree showed a significant positive correlation with the effective connectivity degree in 9/13 patients and at group level after accommodating for node proximity (β = 0.13, 95 %-CI = [0.04, 0.21], t(852) = 2.79, p = 0.0054). SOZ and VEA were no significant predictors for the correlation between structural and effective connectivity.</div><div>We showed a moderate overlap between non-invasive structural (measured with DWI) and invasive effective (measured with SPES) connectivity in epileptic brain networks. This overlap supports using non-invasively determined connectivity along with intracranial EEG to understand the epileptic brain. Future research needs to translate these findings towards network-based surgical strategies.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100274"},"PeriodicalIF":0.0,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of protocol factors and participant characteristics on functional near-infrared spectroscopy data quality after stroke","authors":"Erin L. Meier ,&nbsp;Lisa D. Bunker ,&nbsp;Hana Kim ,&nbsp;Alexandra Zezinka Durfee ,&nbsp;Victoria Tilton-Bolowsky ,&nbsp;Voss Neal ,&nbsp;Argye E. Hillis","doi":"10.1016/j.ynirp.2025.100276","DOIUrl":"10.1016/j.ynirp.2025.100276","url":null,"abstract":"<div><div>Functional Near-Infrared Spectroscopy (fNIRS) is an emerging neurotechnology that has several advantages over fMRI, but questions remain about factors that affect data quality and activity in stroke survivors. We examined the effect of protocol factors (Aim 1) and participant characteristics (Aim 2) on raw fNIRS signal quality and tested associations between quality control metrics and brain activity and connectivity (Aim 3) in a sample of 107 individuals with a history of left or right hemisphere stroke. Participants completed tasks that varied by cognitive and motor speech demands (from low to high): Resting State, Discourse Comprehension, and Picture Naming. Scalp-coupling indices, peak spectral power values, and number of bad channels from each task were extracted from the Quality Testing of Near Infrared Scans (QT-NIRS) toolbox (Montero-Hernandez and Pollonini, 2020) and used to index raw data quality. Data quality did not vary by session location or protocol experience, but all data quality metrics from Picture Naming were significantly lower than those from the other tasks. fNIRS signals were generally worse for Black women compared to Black men and White individuals regardless of gender. No significant associations between the raw fNIRS signal quality and Resting State functional connectivity were found. However, relative changes in Picture Naming hemoglobin concentrations were associated with scalp-coupling indices for certain channels. These results highlight the need for careful data preprocessing of already collected data and a systematic approach in future studies to mitigate inherent biases of optical instruments, thereby enhancing the inclusion of underrepresented groups in neuroscience research.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100276"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144470059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Headache-specific hyperexcitation sensitises and habituates on different time scales: An event related potential study of pattern-glare","authors":"Cihan Dogan ,&nbsp;Claire E. Miller ,&nbsp;Tom Jefferis ,&nbsp;Margarita Saranti ,&nbsp;Austyn J. Tempesta ,&nbsp;Andrew J. Schofield ,&nbsp;Ramaswamy Palaniappan ,&nbsp;Howard Bowman","doi":"10.1016/j.ynirp.2025.100271","DOIUrl":"10.1016/j.ynirp.2025.100271","url":null,"abstract":"<div><div>Cortical hyperexcitability is a key pathophysiological feature in several neurological disorders, including migraine, epilepsy, tinnitus, and Alzheimer's disease. We examined the temporal characteristics of Event Related Potentials (ERPs) in a healthy population using the Pattern Glare Test, a diagnostic tool used to assess patients with sensitivity to cortical hyperexcitability. In pre-experiment questionnaires, participants reported their susceptibility to a range of symptoms. A factor analysis over these responses identified three variables, with the one we investigate in this paper loading strongly on headache symptoms, e.g. headache frequency. We investigated two timeframes: habituation over the course of the entire experiment and sensitization over the course of a sequence of stimulus presentations. We found evidence of hyperexcitability at electrodes over visual cortex, for the aggravating stimulus (grating of ∼3 cycles/deg). Participants higher on the headache factor exhibited a higher degree of habituation and sensitization, with evidence that the level of sensitization habituated through the course of the experiment. These findings suggest that the same experimental paradigm and analysis should be performed on a clinically diagnosed population.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100271"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative susceptibility mapping of paramagnetic rim lesions in early multiple sclerosis: A cross-sectional study of brain age and disability","authors":"Lars Skattebøl ,&nbsp;Rigmor Lundby ,&nbsp;Mathias H. Øverås ,&nbsp;Piotr Sowa ,&nbsp;Elisabeth G. Celius ,&nbsp;Hanne F. Harbo ,&nbsp;Wibeke Nordhøy ,&nbsp;Einar A. Høgestøl ,&nbsp;Gro O. Nygaard","doi":"10.1016/j.ynirp.2025.100277","DOIUrl":"10.1016/j.ynirp.2025.100277","url":null,"abstract":"<div><h3>Objective</h3><div>Chronic inflammation in multiple sclerosis is associated with neurodegeneration and progressive functional decline. Quantitative susceptibility mapping (QSM) is an MRI technique that visualizes paramagnetic rim lesions (PRLs), which are indicative of chronic inflammation. In this cross-sectional study, we explored the prevalence of PRLs in multiple sclerosis and assessed their associations with clinical disability, tissue magnetic susceptibility, and brain age predictions.</div></div><div><h3>Methods</h3><div>All participants from the NOR-MS study with a 3T MRI T1-weighted magnetization-prepared rapid gradient echo and QSM were included (n = 42, mean age = 39.4 years, 59.5 % females, median disease duration = 0.1 years [IQR: 0.02–5.42]). The presence and characteristics of PRLs were evaluated by an experienced neuroradiologist. PRL and non-PRL susceptibility were categorized into separate groups through manual segmentation and voxel-wise analysis. We utilized a validated simple fully convolutional network and T1-weighted images to estimate brain age, and its derivative – brain age gap (BAG). Clinical disability was assessed using the Expanded Disability Status Scale (EDSS).</div></div><div><h3>Results</h3><div>PRLs were identified in 14.3 % (n = 6) of study participants, and correlated with EDSS (rho = 0.86, p = 0.03). The mean paramagnetic rim susceptibility was 25.6 ± 14.1 parts per billion and correlated with EDSS (rho = 0.93, p = 0.008). EDSS was significantly higher in the PRL-positive group (median EDSS 2.25 vs 1.5, p = 0.02). The PRL-positive group exhibited a mean 5.6-year higher BAG (p = 0.01) than the PRL-negative group.</div></div><div><h3>Conclusion</h3><div>PRLs were present in a significant subset of study participants with MS and were associated with greater disability and higher BAG.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100277"},"PeriodicalIF":0.0,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"White matter changes with rehabilitation in children with Co-occurring autism spectrum disorder and developmental coordination disorder","authors":"Melika Kangarani-Farahani ,&nbsp;Jill G. Zwicker","doi":"10.1016/j.ynirp.2025.100272","DOIUrl":"10.1016/j.ynirp.2025.100272","url":null,"abstract":"<div><h3>Purpose</h3><div>Up to 88 % of children with autism spectrum disorder (ASD) experience motor difficulties consistent with developmental coordination disorder (DCD). Cognitive Orientation to daily Occupational Performance (CO-OP) intervention is effective for children with co-occurring ASD and DCD to learn motor skills, but it is unknown if treatment-induced brain changes occur in this clinical population. Our objectives were to: (1) investigate changes in white matter microstructure in children with ASD + DCD after CO-OP intervention; (2) determine whether these brain changes are maintained three months after intervention; and (3) explore the relationship of white matter changes with improvements in motor function.</div></div><div><h3>Methods</h3><div>In this quasi-experimental study, 24 children with ASD + DCD (aged 8–12 years) underwent an initial MRI and were randomly assigned to either a treatment or waitlist group. The treatment group received CO-OP intervention (once weekly for 10 weeks), had a second MRI post-intervention, and a follow-up scan three months later. The waitlist group waited three months for their second MRI, received the intervention, and then had a post-treatment scan. Diffusion tensor imaging data were analyzed using tract-based spatial statistics.</div></div><div><h3>Results</h3><div>Children with ASD + DCD showed increased fractional anisotropy in cerebellar white matter in vermal lobule VI and middle cerebellar peduncle after CO-OP (Cohen's d = 0.88 and 0.85, respectively). Brain changes were maintained three months post-intervention. Regression analysis found no relationship between white matter changes and motor outcomes.</div></div><div><h3>Conclusions</h3><div>Improvements in cerebellar white matter pathways in children with ASD + DCD highlight the efficacy of CO-OP interventions as a therapeutic approach for this clinical population.</div></div><div><h3>Clinical trials registration</h3><div>ClinicalTrials.gov ID: NCT04119492.</div></div>","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative MRI-based decision model for early-stage parkinsonism diagnosis: a pilot feasibility study","authors":"Laura Nunez-Gonzalez ,&nbsp;Elise G.P. Dopper ,&nbsp;Anke W. van der Eerden ,&nbsp;Samy Abo Seada ,&nbsp;Agnita J.W. Boon ,&nbsp;Marcel M. Verbeek ,&nbsp;Bastiaan R. Bloem ,&nbsp;Frederick Jan Anton Meijer ,&nbsp;Juan Antonio Hernandez-Tamames","doi":"10.1016/j.ynirp.2025.100273","DOIUrl":"10.1016/j.ynirp.2025.100273","url":null,"abstract":"","PeriodicalId":74277,"journal":{"name":"Neuroimage. Reports","volume":"5 3","pages":"Article 100273"},"PeriodicalIF":0.0,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144279814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}