Minerva gastroenterologica e dietologica最新文献_第5页

Helicobacter pylori and non-alcoholic fatty liver disease. 幽门螺杆菌与非酒精性脂肪肝

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 DOI: 10.23736/S1121-421X.20.02671-9

György M Buzás

{"title":"Helicobacter pylori and non-alcoholic fatty liver disease.","authors":"György M Buzás","doi":"10.23736/S1121-421X.20.02671-9","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02671-9","url":null,"abstract":"Helicobacter pylori is the most prevalent infection worldwide, while non-alcoholic fatty liver disease emerged as the most frequent liver disease. The common occurrence can be either by chance or due to certain pathogenetic factors. Epidemiologic studies revealed that the risk of non-alcoholic liver disease is increased in patients infected with Helicobacter pylori. DNA fragments of Helicobacter pylori were rarely identified in human samples of liver carcinoma and fatty liver. Helicobacter pylori could influence the development of non-alcoholic fatty liver either by hormonal (ghrelin? gastrin? insulin?), or by effect of pro-inflammatory cytokines (interleukin 1 and 8, tumor necrosis factor ɑ, interferon ɣ) and by changes of gut microbiome as well. Probiotic supplementation could improve some clinical parameters of non-alcoholic fatty liver disease and eradication rates of Helicobacter pylori. Regimens used for eradication can be safely administered, although non-alcoholic fatty liver increases the risk of drug-induced liver damage. Controlled studies of the effect of eradication on the development and progression of non-alcoholic fatty liver are warranted.","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":" ","pages":"267-279"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38202882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Factors influencing inpatient colonoscopy bowel preparation quality. 影响住院患者结肠镜下肠准备质量的因素。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 DOI: 10.23736/S1121-421X.20.02657-4

Shiva Poola, Nannaya Jampala, Dmitry Tumin, Eslam Ali

{"title":"Factors influencing inpatient colonoscopy bowel preparation quality.","authors":"Shiva Poola, Nannaya Jampala, Dmitry Tumin, Eslam Ali","doi":"10.23736/S1121-421X.20.02657-4","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02657-4","url":null,"abstract":"Background: Colonoscopy is highly sensitive for the visualization of the entire colon. Inpatient colonoscopies pose a special risk of poor preparation. We reviewed bowel preparation methods and patient factors to identify predictors of inadequate bowel preparation for inpatient colonoscopy at our institution. The purpose of this study was to identify factors that predict inadequate bowel preparation for inpatient colonoscopies.Methods: All patients ages >18 years of age undergoing inpatient colonoscopy in 2017-2018 were reviewed. The primary outcome was inadequate bowel preparation and secondary outcomes were successful cecal intubation, duration of colonoscopy, and hospital length of stay (LOS). Outcomes were compared using multivariable regression with stepwise covariate selection.Results: The analysis included 315 patients (median age =67 years; 45% female). Visualization was deemed adequate in 56%, fair in 27%, and poor in 17% of cases. Cecal intubation was successful in 84% of cases. The median duration of colonoscopy was 25 min and LOS was 2 days. Unsuccessful cecal intubation was most likely with poor visualization compared to adequate visualization (36% vs. 11%, P=0.014). There was no increased colonoscopy duration with poor visualization (P=0.075). There was no significant LOS with worse visualization quality (P=0.185). Factors predicting worse visualization quality included older age, history of congestive heart failure (CHF), cirrhosis, and motility disorders.Conclusions: At our institution, patients who were older or had significant comorbid conditions (chronic artery disease, CHF, chronic obstructive pulmonary disease, motility disorders, or cirrhosis) were more likely to have inadequate inpatient bowel preparation. Bowel preparation type did not affect the duration, quality of visualization, or successful cecal intubation.","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":"66 3","pages":"194-200"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10850962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Management of alcohol-related liver disease in liver transplant candidate patients. 肝移植候选者酒精相关性肝病的治疗

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-03-24 DOI: 10.23736/S1121-421X.20.02689-6

Gianni Testino, Patrizia Balbinot, Silvia Leone, Rinaldo Pellicano

引用次数: 8

Pilot study on non-celiac gluten sensitivity: effects of Bifidobacterium longum ES1 co-administered with a gluten-free diet. 非乳糜泻麸质敏感性的初步研究:长双歧杆菌ES1与无麸质饮食共同施用的影响。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-05-12 DOI: 10.23736/S1121-421X.20.02673-2

Francesco Di Pierro, Francesca Bergomas, Paolo Marraccini, Maria R Ingenito, Lorena Ferrari, Luisella Vigna

{"title":"Pilot study on non-celiac gluten sensitivity: effects of Bifidobacterium longum ES1 co-administered with a gluten-free diet.","authors":"Francesco Di Pierro, Francesca Bergomas, Paolo Marraccini, Maria R Ingenito, Lorena Ferrari, Luisella Vigna","doi":"10.23736/S1121-421X.20.02673-2","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02673-2","url":null,"abstract":"Background: Bifidobacterium longum ES1 is a strain probiotic, colonizing the human gut and capable of a degradative action on gliadin. In an attempt to find new nutritional solutions aimed at improving the quality of life of patients with non-celiac gluten sensitivity (NCGS) we evaluated the effectiveness of this strain, in association with a gluten-free diet, comparing its efficacy versus diet therapy alone.Methods: The experimental design included a non-randomized, open-label, 1:1 intervention study in parallel groups. Enrolled patients with symptoms attributable to NCGS, and with negative diagnoses of both wheat allergy and celiac disease, were included in this three-month trial divided into four outpatient visits (baseline, T1, T2 and T3). Fifteen patients for each group completed the experimental protocol.Results: Our results showed that a combination of diet and probiotic determined a more significant reduction in the frequency and intensity of intestinal and extra-intestinal symptoms, and a clear improvement in stool consistency.Conclusions: Although the study was carried out on a small number of patients, the results of our pilot trial suggest that a combined strategy of naturally gluten-free diet therapy with administration of the probiotic strain ES1 appears to offer a greater advantage than the dietary regime alone in improving the clinical symptomatic picture and in stabilizing the intestinal microbiota.","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":" ","pages":"187-193"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37927370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The efficacy of fasting regimens on health outcomes: a systematic overview. 禁食方案对健康结果的功效:系统概述。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 DOI: 10.23736/S1121-421X.20.02757-9

A. Sarro, A. B. Payedimarri, D. Concina, M. Farsoni, N. Piu, M. Panella

{"title":"The efficacy of fasting regimens on health outcomes: a systematic overview.","authors":"A. Sarro, A. B. Payedimarri, D. Concina, M. Farsoni, N. Piu, M. Panella","doi":"10.23736/S1121-421X.20.02757-9","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02757-9","url":null,"abstract":"INTRODUCTION\u0000Fasting can be defined as abstinence or reduction from food, drink, or both, for a defined period. There are many different types of fasting regimens, such as Ramadan fasting, Intermittent fasting, Christian Orthodox fasting. The aim of this overview is to provide an exhaustive summary on the beneficial effects and harms associated with fasting regimens and discuss mechanisms by which this non - pharmacological approach might lead to improve human health.\u0000\u0000\u0000EVIDENCE ACQUISITION\u0000A systematic search was performed on MEDLINE (PubMed), Embase, Cochrane Library and CINHAL. We included systematic reviews (SRs) that report on impact of different types of fasting regimens on health. Selection of SRs, data extraction and quality assessment were undertaken in duplicate.\u0000\u0000\u0000EVIDENCE SYNTHESIS\u0000A total of 21 SRs were included. Cumulatively, 97 health outcomes were identified. Of them, cardiovascular risk factors were the most frequently analyzed. Ramadan fasting is associated with significant improvements in body weight and visceral lean mass, high-density lipoprotein cholesterol (HDL-c), and with reductions in low-density lipoprotein cholesterol (LDL-c) and total cholesterol (T-chol), especially in cardiac patients. Similarly, reviews on Intermittent and Orthodox fasting proved benefits of those on weight, BMI, lipidic and glucose profile, inflammatory markers.\u0000\u0000\u0000CONCLUSIONS\u0000Fasting regimens showed potential beneficial effects on several health indicators in adult populations. Nevertheless, evidence on some specific health dimensions (cognitive function, well-being, quality of life) is limited. Thus, in the future, further RCTs or cohort studies with good methodological quality and larger sample sizes are warranted to better understand the underlying biological mechanism and the benefits on multidimensional aspects of health.","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88114537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Fecal gluten immunogenic peptides as indicators of dietary compliance in celiac patients. 粪便谷蛋白免疫原性肽作为乳糜泻患者饮食依从性的指标。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-03-24 DOI: 10.23736/S1121-421X.20.02662-8

Brunetta Porcelli, Fabio Ferretti, Francesca Cinci, Ivano Biviano, Alessia Santini, Elisabetta Grande, Francesco Quagliarella, Lucia Terzuoli, Maria R Bacarelli, Nicola Bizzaro, Marina Vascotto, Mario Marini

{"title":"Fecal gluten immunogenic peptides as indicators of dietary compliance in celiac patients.","authors":"Brunetta Porcelli, Fabio Ferretti, Francesca Cinci, Ivano Biviano, Alessia Santini, Elisabetta Grande, Francesco Quagliarella, Lucia Terzuoli, Maria R Bacarelli, Nicola Bizzaro, Marina Vascotto, Mario Marini","doi":"10.23736/S1121-421X.20.02662-8","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02662-8","url":null,"abstract":"Background: It is important to have methods for evaluating dietary compliance in patients with celiac disease (CD). Determination of fecal gluten immunogenic peptides (GIPs) was recently proposed as a method of detecting gluten intake. The aim of this study was to evaluate whether determination of GIPs can be used as an indicator of compliance with a gluten-free diet (GFD).Methods: Twenty-five persons with CD on a gluten-free diet for at least one year were enrolled in the study. Compliance with the diet was assessed by the Biagi questionnaire, evaluation of symptoms and assay of IgA anti-tissue transglutaminase antibodies (IgA anti-tTG). GIPs were determined by iVYLISA GIP-S test (Biomedal S.L., Seville, Spain) on an automated Chorus analyzer (DIESSE Diagnostica Senese, Siena, Italy), after extraction of fecal samples by the method developed by DIESSE.Results: Four patients tested positive for GIPs (GIP+), two of whom complied strictly with the gluten-free diet according to the Biagi questionnaire. None of the four GIP-positive patients manifested symptoms. IgA anti-tTG was significantly higher in GIP+ than in GIP- subjects.Conclusions: Assay of fecal GIPs identified more patients who were not complying with the diet than the Biagi questionnaire or evaluation of symptoms. The anti-tTG and GIP results agreed perfectly; however, since anti-tTG antibodies remain high for longer and are not a completely reliable marker of GFD intake, detection of fecal GIPs offers a direct, objective, quantitative assessment of exposure, even occasional, to gluten and could be used to check dietary compliance.","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":" ","pages":"201-207"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37776184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Effects of Hoodia Parviflora on satiety, abdominal obesity and weight in a group of overweight subjects: a randomized, blinded, placebo-controlled trial. 细小花对一组超重受试者的饱腹感、腹部肥胖和体重的影响:一项随机、盲法、安慰剂对照试验。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-03-24 DOI: 10.23736/S1121-421X.20.02669-0

Simone Perna, Vittoria Infantino, Gabriella Peroni, Clara Gasparri, Milena A Faliva, Maurizio Naso, Tariq A Alalwan, Filippo Borsani, Martina Berardi, Zahra Ilyas, Zahraa Alaali, Layla Alsowaid, Daniele Spadaccini, Mariangela Rondanelli

{"title":"Effects of Hoodia Parviflora on satiety, abdominal obesity and weight in a group of overweight subjects: a randomized, blinded, placebo-controlled trial.","authors":"Simone Perna, Vittoria Infantino, Gabriella Peroni, Clara Gasparri, Milena A Faliva, Maurizio Naso, Tariq A Alalwan, Filippo Borsani, Martina Berardi, Zahra Ilyas, Zahraa Alaali, Layla Alsowaid, Daniele Spadaccini, Mariangela Rondanelli","doi":"10.23736/S1121-421X.20.02669-0","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02669-0","url":null,"abstract":"Background: This study aimed to assess the effects of supplementation with Hoodia Parviflora (H. Parviflora) at 9 mg+200 mg of fructo-oligosaccharides on weight loss, body composition, hydration and satiety parameters.Methods: A randomized blinded controlled trial was conducted in a sample of 30 overweight and obese patients (5 males and 25 females). Patients were randomly assigned in 2 groups: the intervention group, which received H. Parviflora twice a day for 4 weeks and the control group, which received a placebo.Results: After a 4-week follow-up period, the study results showed an improvement of Δ=-1.632 kg (Confidence Interval [CI]95% -2.545; -0.719) and a statistically significant decrease in waist circumference (WC) compared with the placebo group -2.080 cm ([CI]95% -4.082; -0.078). The visual analogue scale reported an improvement of satiety sensation after day 5 (P=0.001).Conclusions: This study shows for the first time the simultaneous effect of H. Parviflora on weight loss, decreasing satiety, and improving fat mass, in particular Visceral Adipose Tissue (VAT).","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":" ","pages":"211-218"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37777667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Proctitis: a glance beyond inflammatory bowel diseases. 直肠炎:超越炎性肠病的一瞥。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-03-24 DOI: 10.23736/S1121-421X.20.02670-7

Stefano Rizza, Massimiliano Mistrangelo, Davide G Ribaldone, Mario Morino, Marco Astegiano, Giorgio M Saracco, Rinaldo Pellicano

{"title":"Proctitis: a glance beyond inflammatory bowel diseases.","authors":"Stefano Rizza, Massimiliano Mistrangelo, Davide G Ribaldone, Mario Morino, Marco Astegiano, Giorgio M Saracco, Rinaldo Pellicano","doi":"10.23736/S1121-421X.20.02670-7","DOIUrl":"https://doi.org/10.23736/S1121-421X.20.02670-7","url":null,"abstract":"Proctitis is an inflammation involving the anus and the distal part of the rectum, frequently diagnosed in the context of inflammatory bowel diseases (IBD). Nevertheless, when the standard therapy for IBD is ineffective, it becomes necessary for the clinician to review alternative etiologies, beginning from the broad chapter of infectious causes up to rare causes such as radiation, ischemia, diversion and traumatisms. While it is possible to find infectious proctitides caused by pathogens generally inducing extensive colitis, the growing incidence of both sexually transmitted infections and isolated proctitis reported in the recent years require a lot of attention. The risk appears to be higher in individuals participating in anal intercourse, especially men having sex with men (MSM) or subjects who use sex toys and participate to sex parties, dark rooms and so on. The commonest implicated pathogens are Neysseria gonorrhoeae, Chlamydia trachomatis, Herpes Simplex virus and Treponema pallidum. Herpes and Chlamydia infections mainly occur in HIV-positive MSM patients. Since symptoms and signs are common independently from etiology, performing a differential diagnosis based on clinical manifestations is complicated. Therefore, the diagnosis is supported by the combination of clinical history and physical examination and, secondly, by endoscopic, serologic and microbiologic findings. Particular emphasis should be given to simultaneous infections by multiple organisms. The involvement of experts in infectious diseases and in sexual health is crucial for the diagnostic and therapeutic management. The available therapies, empirically initiated or specific, in many cases are able to guarantee a good prognosis and to prevent relapses.","PeriodicalId":74201,"journal":{"name":"Minerva gastroenterologica e dietologica","volume":" ","pages":"252-266"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37777669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Acute pancreatitis: an overview. 急性胰腺炎:综述。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-04-08 DOI: 10.23736/S1121-421X.20.02681-1

Jean Le'clerc Nicolas, Lucia Romano, Antonio Giuliani

引用次数: 0

Hypertriglyceridemic pancreatitis. Hypertriglyceridemic胰腺炎。

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 DOI: 10.23736/S1121-421X.19.02641-2

Nicolò De Pretis, Giulia De Marchi, Luca Frulloni

引用次数: 4