Effects of Hoodia Parviflora on satiety, abdominal obesity and weight in a group of overweight subjects: a randomized, blinded, placebo-controlled trial.

Minerva gastroenterologica e dietologica Pub Date : 2020-09-01 Epub Date: 2020-03-24 DOI:10.23736/S1121-421X.20.02669-0

Simone Perna, Vittoria Infantino, Gabriella Peroni, Clara Gasparri, Milena A Faliva, Maurizio Naso, Tariq A Alalwan, Filippo Borsani, Martina Berardi, Zahra Ilyas, Zahraa Alaali, Layla Alsowaid, Daniele Spadaccini, Mariangela Rondanelli

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引用次数: 1

Abstract

Background: This study aimed to assess the effects of supplementation with Hoodia Parviflora (H. Parviflora) at 9 mg+200 mg of fructo-oligosaccharides on weight loss, body composition, hydration and satiety parameters.

Methods: A randomized blinded controlled trial was conducted in a sample of 30 overweight and obese patients (5 males and 25 females). Patients were randomly assigned in 2 groups: the intervention group, which received H. Parviflora twice a day for 4 weeks and the control group, which received a placebo.

Results: After a 4-week follow-up period, the study results showed an improvement of Δ=-1.632 kg (Confidence Interval [CI]95% -2.545; -0.719) and a statistically significant decrease in waist circumference (WC) compared with the placebo group -2.080 cm ([CI]95% -4.082; -0.078). The visual analogue scale reported an improvement of satiety sensation after day 5 (P=0.001).

Conclusions: This study shows for the first time the simultaneous effect of H. Parviflora on weight loss, decreasing satiety, and improving fat mass, in particular Visceral Adipose Tissue (VAT).

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细小花对一组超重受试者的饱腹感、腹部肥胖和体重的影响:一项随机、盲法、安慰剂对照试验。

背景:本研究旨在评估添加9 mg+200 mg低聚果糖对体重减轻、体成分、水合作用和饱腹感参数的影响。方法:对30例超重肥胖患者(男5例，女25例)进行随机盲法对照试验。患者被随机分为两组:干预组，每天两次，连续4周;对照组，给予安慰剂。结果:随访4周后，研究结果显示改善Δ=-1.632 kg(置信区间[CI]95% -2.545;-0.719)，腰围(WC)与安慰剂组-2.080 cm相比有统计学意义的降低([CI]95% -4.082;-0.078)。视觉模拟量表报告第5天后饱腹感改善(P=0.001)。结论:本研究首次显示了细小菌群在减肥、降低饱腹感和改善脂肪量方面的同时作用，特别是内脏脂肪组织(VAT)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Minerva gastroenterologica e dietologica

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